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| | CD44 | CD44 molecule (Indian blood group). (767 aa) |
| | C3 | Complement C3c alpha' chain fragment 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates (By similarity). [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation. (1661 aa) |
| | ANGPTL4 | Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stre [...] (412 aa) |
| | GMIP | GEM interacting protein. (1090 aa) |
| | CAST | Calpastatin; Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue; Belongs to the protease inhibitor I27 (calpastatin) family. (835 aa) |
| | FNIP1 | Folliculin interacting protein 1. (1061 aa) |
| | SPINK9 | Serine peptidase inhibitor, Kazal type 9. (84 aa) |
| | PICALM | Phosphatidylinositol binding clathrin assembly protein. (700 aa) |
| | TMEM225 | Uncharacterized protein. (233 aa) |
| | TFPI2 | Tissue factor pathway inhibitor. (232 aa) |
| | HGF | Hepatocyte growth factor; Belongs to the peptidase S1 family. (814 aa) |
| | VIL1 | Villin-1; Epithelial cell-specific Ca(2+)-regulated actin-modifying protein that modulates the reorganization of microvillar actin filaments. Plays a role in the actin nucleation, actin filament bundle assembly, actin filament capping and severing. Binds phosphatidylinositol 4,5-bisphosphate (PIP2) and lysophosphatidic acid (LPA); binds LPA with higher affinity than PIP2. Binding to LPA increases its phosphorylation by SRC and inhibits all actin-modifying activities. Binding to PIP2 inhibits actin-capping and -severing activities but enhances actin-bundling activity. Regulates the inte [...] (826 aa) |
| | WAP | Whey acidic protein; Could be a protease inhibitor. May play an important role in mammary gland development and tissue remodeling. (132 aa) |
| | GZMA | Granzyme A; Belongs to the peptidase S1 family. (258 aa) |
| | GZMA-2 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (259 aa) |
| | BOD1 | Uncharacterized protein. (267 aa) |
| | PTTG1 | Securin; Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes. At the onset of anaphase, it is ubiquitinated, conducting to its destruction and to the liberation of ESPL1. Its function is however not limited to a blocking activity, since it is required to activate ESPL1. Negatively regulates the transcriptional activity a [...] (202 aa) |
| | WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (580 aa) |
| | LOC396905 | Sperm-associated acrosin inhibitor; Inhibits acrosin. (162 aa) |
| | DPEP1 | Dipeptidase 1; Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (409 aa) |
| | SPHK2 | Sphingosine kinase 2. (653 aa) |
| | USP14 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (505 aa) |
| | VTN | Vitronectin; Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway (By similarity). (523 aa) |
| | ECM1 | Extracellular matrix protein 1. (559 aa) |
| | CSTB | Cystatin-B; This is an intracellular thiol proteinase inhibitor; Belongs to the cystatin family. (98 aa) |
| | PCSK1N | Proprotein convertase subtilisin/kexin type 1 inhibitor. (259 aa) |
| | STYXL1 | Serine/threonine/tyrosine-interacting-like protein 1 isoform X1. (313 aa) |
| | LOC100524679 | Uncharacterized protein. (1397 aa) |
| | LEPR | Leptin receptor; Receptor for hormone LEP/leptin (By similarity). On ligand binding, mediates LEP central and peripheral effects through the activation of different signaling pathways such as JAK2/STAT3 and MAPK cascade/FOS. In the hypothalamus, LEP acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal metabolism, influences reproductiv [...] (1165 aa) |
| | URI1 | URI1 prefoldin like chaperone. (537 aa) |
| | PSMF1 | Uncharacterized protein. (351 aa) |
| | WFDC5 | WAP four-disulfide core domain 5. (166 aa) |
| | R3HDML | R3H domain containing like. (252 aa) |
| | AVP | Vasopressin-neurophysin 2-copeptin. (217 aa) |
| | CST7 | Cystatin domain-containing protein. (146 aa) |
| | CST8 | Cystatin domain-containing protein. (274 aa) |
| | LOC100515765 | Cystatin domain-containing protein. (128 aa) |
| | CST11 | Cystatin 11. (137 aa) |
| | CSTL1 | Cystatin like 1. (137 aa) |
| | MKKS | McKusick-Kaufman syndrome. (570 aa) |
| | IKBKB | Inhibitor of kappa light chain gene enhancer in B cells, kinase beta. (755 aa) |
| | TIPRL | TOR signaling pathway regulator. (267 aa) |
| | PI15 | Peptidase inhibitor 15; Belongs to the CRISP family. (258 aa) |
| | CRB2 | Crumbs cell polarity complex component 2. (1283 aa) |
| | DAB2IP | DAB2 interacting protein. (1196 aa) |
| | ANXA1 | Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...] (346 aa) |
| | SERPINB5 | Serpin family B member 5; Belongs to the serpin family. (375 aa) |
| | SERPINB7 | Serpin family B member 7; Belongs to the serpin family. (380 aa) |
| | SERPINB2 | Plasminogen activator inhibitor 2; Belongs to the serpin family. (440 aa) |
| | SERPINB10 | SERPIN domain-containing protein; Belongs to the serpin family. (397 aa) |
| | SERPINB8 | Serpin family B member 8; Belongs to the serpin family. (374 aa) |
| | THBS1 | Uncharacterized protein. (1170 aa) |
| | MICAL1 | Microtubule associated monooxygenase, calponin and LIM domain containing 1. (1122 aa) |
| | ANGPTL3 | Fibrinogen C-terminal domain-containing protein. (461 aa) |
| | DFFA | DNAation factor subunit alpha isoform 1. (330 aa) |
| | PARK7 | DJ-1 protein. (189 aa) |
| | PPP1R15A | Protein phosphatase 1 regulatory subunit 15A. (654 aa) |
| | TERF2 | Telomeric repeat-binding factor 2. (542 aa) |
| | LOC396684 | SERPIN domain-containing protein; Belongs to the serpin family. (411 aa) |
| | LOC106504545 | SERPIN domain-containing protein; Belongs to the serpin family. (417 aa) |
| | UABP-2 | Uteroferrin-associated basic protein 2. (420 aa) |
| | SERPINA11 | Serpin family A member 11; Belongs to the serpin family. (514 aa) |
| | SERPINA12 | Serpin family A member 12; Belongs to the serpin family. (414 aa) |
| | SERPINA1 | Alpha-1-antitrypsin; Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin (By similarity). (420 aa) |
| | SERPINA6 | Corticosteroid-binding globulin; Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. (434 aa) |
| | PAPLN | Papilin, proteoglycan like sulfated glycoprotein. (961 aa) |
| | PPP1R36 | Protein phosphatase 1 regulatory subunit 36. (283 aa) |
| | NEIL1 | Nei like DNA glycosylase 1. (463 aa) |
| | PI16 | SCP domain-containing protein; Belongs to the CRISP family. (460 aa) |
| | PPP1R11 | Protein phosphatase 1 regulatory inhibitor subunit 11. (126 aa) |
| | SERPINB1 | Leukocyte elastase inhibitor; Neutrophil serine protease inhibitor that plays an essential role in the regulation of the innate immune response, inflammation and cellular homeostasis. Acts primarily to protect the cell from proteases released in the cytoplasm during stress or infection. These proteases are important in killing microbes but when released from granules, these potent enzymes also destroy host proteins and contribute to mortality. Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Acts also as a [...] (413 aa) |
| | LRRK2 | Uncharacterized protein. (2501 aa) |
| | CD27 | CD27. (249 aa) |
| | A2ML1 | Alpha-2-macroglobulin like 1. (1457 aa) |
| | A2M | Alpha-2-macroglobulin. (1504 aa) |
| | WFDC8 | WAP four-disulfide core domain 8. (252 aa) |
| | TIMP4 | TIMP metallopeptidase inhibitor 4. (224 aa) |
| | BIRC3 | Baculoviral IAP repeat containing 3. (603 aa) |
| | MMP9 | Matrix metalloproteinase-9. (708 aa) |
| | SERPINF1 | Serpin family F member 1; Belongs to the serpin family. (433 aa) |
| | SERPINE2 | SERPIN domain-containing protein; Belongs to the serpin family. (378 aa) |
| | PTI | BPTI/Kunitz inhibitor domain-containing protein. (247 aa) |
| | GAS6 | Uncharacterized protein. (682 aa) |
| | A0A287AXL0_PIG | Uncharacterized protein. (502 aa) |
| | IFI6 | Interferon alpha inducible protein 6. (171 aa) |
| | NOS3 | Nitric oxide synthase, endothelial; Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets (By similarity). (1239 aa) |
| | TFPI | Tissue factor pathway inhibitor. (303 aa) |
| | SPAI-2 | Sodium/potassium ATPase inhibitor SPAI-2; Inhibits Na(+),K(+) ATPase by the competitive mode against Na(+). (187 aa) |
| | BIN1 | Bridging integrator 1. (588 aa) |
| | CRYAB | Alpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (237 aa) |
| | SIAH2 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (324 aa) |
| | KIF12 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (651 aa) |
| | PPP4R4 | Protein phosphatase 4 regulatory subunit 4. (912 aa) |
| | BAG4 | BAG family molecular chaperone regulator 4 isoform 1. (457 aa) |
| | NR4A1 | Nuclear receptor subfamily 4 group A member 1 isoform 2. (598 aa) |
| | RCC2 | Regulator of chromosome condensation 2. (554 aa) |
| | SERPINB13 | Serpin family B member 13; Belongs to the serpin family. (390 aa) |
| | LOC100621494 | SERPIN domain-containing protein; Belongs to the serpin family. (407 aa) |
| | A0A287AKL9_PIG | WAP four-disulfide core domain protein 15B. (79 aa) |
| | RPS6KA1 | Ribosomal protein S6 kinase. (856 aa) |
| | C5 | Complement C5a anaphylatoxin; Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation. (1677 aa) |
| | SH3BP4 | SH3 domain binding protein 4. (1016 aa) |
| | SPINK14 | Serine peptidase inhibitor, Kazal type 14 (putative). (98 aa) |
| | WFDC10AL | WAP four-disulfide core domain protein 10A. (108 aa) |
| | BIRC5 | Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] (142 aa) |
| | PIH1D1 | PIH1 domain containing 1. (289 aa) |
| | NLE1 | Notchless homolog 1. (487 aa) |
| | TMBIM6 | Bax inhibitor 1; Suppressor of apoptosis. Modulates unfolded protein response signaling. Modulates ER calcium homeostasis by acting as a calcium-leak channel. Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation; Belongs to the BI1 family. (275 aa) |
| | SERPINA5 | Plasma serine protease inhibitor preproprotein; Belongs to the serpin family. (408 aa) |
| | BST2 | Uncharacterized protein. (177 aa) |
| | SPINK6 | Serine peptidase inhibitor, Kazal type 6. (80 aa) |
| | WFDC11 | WAP four-disulfide core domain 11. (90 aa) |
| | XIAP | X-linked inhibitor of apoptosis. (514 aa) |
| | AGT | Angiotensinogen; Belongs to the serpin family. (482 aa) |
| | A0A5G2RGT7_PIG | Uncharacterized protein. (147 aa) |
| | A0A5G2RMR0_PIG | WAP domain-containing protein. (128 aa) |
| | BIRC7-2 | Uncharacterized protein. (428 aa) |
| | ABCE1 | ATP binding cassette subfamily E member 1. (589 aa) |
| | A0A5G2R112_PIG | BPTI/Kunitz inhibitor domain-containing protein. (84 aa) |
| | F11R | Uncharacterized protein. (347 aa) |
| | APOA2 | Apolipoprotein A-II preproprotein. (100 aa) |
| | RPS6KA3 | Ribosomal protein S6 kinase. (744 aa) |
| | KNG1 | Kininogen 1. (630 aa) |
| | SPRY2 | Sprouty RTK signaling antagonist 2. (315 aa) |
| | LOC100516119 | Cystatin domain-containing protein. (186 aa) |
| | SPINK8 | Serine peptidase inhibitor, Kazal type 8 (putative). (95 aa) |
| | SPRY1 | Sprouty RTK signaling antagonist 1. (319 aa) |
| | MASTL | Microtubule associated serine/threonine kinase like. (881 aa) |
| | SLC27A4 | Solute carrier family 27 member 4. (673 aa) |
| | SERPINC1 | SERPIN domain-containing protein; Belongs to the serpin family. (431 aa) |
| | TIMP2 | Uncharacterized protein. (257 aa) |
| | TNFSF14 | Tumor necrosis factor ligand superfamily member 14 isoform 1. (241 aa) |
| | BBS4 | Uncharacterized protein. (826 aa) |
| | LOC100158011 | BPTI/Kunitz inhibitor domain-containing protein. (128 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1128 aa) |
| | PPP1R1B | Protein phosphatase 1 regulatory subunit 1B; Inhibitor of protein-phosphatase 1. (200 aa) |
| | CSNK2A1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (398 aa) |
| | PPP1R14C | Protein phosphatase 1 regulatory inhibitor subunit 14C. (175 aa) |
| | RARRES1 | Retinoic acid receptor responder protein 1 isoform X1. (290 aa) |
| | TMEM225B | Uncharacterized protein. (257 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa) |
| | UBXN1 | UBX domain protein 1. (310 aa) |
| | RECK | Reversion-inducing cysteine-rich protein with Kazal motifs isoform 1. (971 aa) |
| | USP47 | Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1356 aa) |
| | APOC3 | Apolipoprotein C-III; Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors. Formed of several curved helices connected via semiflexible hinges, so that it can wrap tigh [...] (199 aa) |
| | SPINK5 | Serine peptidase inhibitor, Kazal type 5. (1023 aa) |
| | LOC100739218 | Uncharacterized protein. (143 aa) |
| | PPP1R14D | Protein phosphatase 1 regulatory inhibitor subunit 14D. (183 aa) |
| | PLIN5 | Perilipin 5. (736 aa) |
| | SPINK13 | Kazal-like domain-containing protein. (173 aa) |
| | SERPINI1 | Serpin family I member 1; Belongs to the serpin family. (502 aa) |
| | C4A | Uncharacterized protein. (1758 aa) |
| | PPP1R26 | Protein phosphatase 1 regulatory subunit 26. (1170 aa) |
| | LOC100517145 | Uncharacterized protein. (1670 aa) |
| | AQP1 | Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. (280 aa) |
| | ANXA8 | Annexin. (354 aa) |
| | TNFAIP8 | TNF alpha induced protein 8. (212 aa) |
| | GNAT1 | Guanine nucleotide-binding protein G(T) subunit alpha-1 isoform X2. (350 aa) |
| | FAM124A | Family with sequence similarity 124 member A. (591 aa) |
| | A0A287BQB3_PIG | Uncharacterized protein. (149 aa) |
| | ITIH3 | Inter-alpha-trypsin inhibitor heavy chain 3. (907 aa) |
| | SORL1 | Sortilin related receptor 1. (2213 aa) |
| | TMEM132D | Transmembrane protein 132D. (1098 aa) |
| | SPINK1 | Serine protease inhibitor Kazal-type 1; Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin- catalyzed premature activation of zymogens (By similarity). (79 aa) |
| | SERPINB9 | SERPIN domain-containing protein; Belongs to the serpin family. (495 aa) |
| | PZP | Uncharacterized protein. (1416 aa) |
| | LRP11 | LDL receptor related protein 11. (517 aa) |
| | NGF | Beta-nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (By similarity). The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone colla [...] (385 aa) |
| | SERPINA3-2 | SERPIN domain-containing protein; Belongs to the serpin family. (473 aa) |
| | SERPINB6 | SERPIN domain-containing protein; Belongs to the serpin family. (399 aa) |
| | BIRC7 | RING-type domain-containing protein. (151 aa) |
| | COL28A1 | Collagen type XXVIII alpha 1 chain. (1236 aa) |
| | SPINT2 | Serine peptidase inhibitor, Kunitz type 2. (252 aa) |
| | TTC8 | Tetratricopeptide repeat domain 8. (587 aa) |
| | FURIN | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (797 aa) |
| | SPINK2 | Serine protease inhibitor Kazal-type 2 isoform 1. (85 aa) |
| | PI3 | Elafin; Neutrophil and pancreatic elastase-specific inhibitor of skin. It may prevent elastase-mediated tissue proteolysis (By similarity). (167 aa) |
| | LOC100153783 | Ovalbumin isoform X1; Belongs to the serpin family. (385 aa) |
| | SPINT1 | Serine peptidase inhibitor, Kunitz type 1. (531 aa) |
| | AHSG | Alpha-2-HS-glycoprotein. (394 aa) |
| | CST3 | Cystatin C; Belongs to the cystatin family. (146 aa) |
| | RFFL | Uncharacterized protein. (799 aa) |
| | ABL1 | Tyrosine-protein kinase. (1146 aa) |
| | LAMTOR5 | Ragulator complex protein LAMTOR5; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. When complexed to BIRC5, interferes with apoptosome assem [...] (229 aa) |
| | SERPINF2 | Alpha-2-antiplasmin isoform X2; Belongs to the serpin family. (563 aa) |
| | A0A287B8V2_PIG | WAP domain-containing protein. (73 aa) |
| | PLAUR | Plasminogen activator, urokinase receptor. (330 aa) |
| | LOC100512873 | Antileukoproteinase. (157 aa) |
| | UBE2O | Ubiquitin conjugating enzyme E2 O. (1296 aa) |
| | TMEM132C | Transmembrane protein 132C. (1132 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | A0A287B396_PIG | WAP domain-containing protein. (73 aa) |
| | ITIH1 | Inter-alpha-trypsin inhibitor heavy chain H1; May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. (927 aa) |
| | ARL2 | ADP-ribosylation factor-like protein 2 isoform 1; Belongs to the small GTPase superfamily. Arf family. (211 aa) |
| | PTX4 | Pentraxin 4. (477 aa) |
| | NOL3 | Nucleolar protein 3. (237 aa) |
| | SEMA4D | Semaphorin-4D isoform X1; Belongs to the semaphorin family. (865 aa) |
| | AMBP | Inter-alpha-trypsin inhibitor light chain; Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization; In the N-terminal section; belongs to the calycin superfamily. Lipocalin family. (364 aa) |
| | CD109 | CD109 antigen isoform 1 preproprotein. (1449 aa) |
| | SLC39A14 | Solute carrier family 39 member 14. (531 aa) |
| | SPINK7 | Serine peptidase inhibitor, Kazal type 7 (putative). (85 aa) |
| | COL6A3 | Collagen type VI alpha 3 chain. (2911 aa) |
| | FAM124B | Family with sequence similarity 124 member B. (454 aa) |
| | CST9L | Cystatin-9-like. (149 aa) |
| | UBE2Z | Ubiquitin-conjugating enzyme E2 Z. (356 aa) |
| | LTF | Lactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity. Shows a preferential cleavage at -Arg-Ser-Arg-Arg-|- and -Arg-Arg-Ser-Arg-|-, and of Z-Phe-Arg-|-aminomethylcoumarin sites. (704 aa) |
| | SERPINE1 | Plasminogen activator inhibitor 1; Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase- type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. I [...] (401 aa) |
| | UPTI | Uterine plasmin/trypsin inhibitor; Inhibitor of plasmin and trypsin. Also has a weak affinity for chymotrypsin. Could serve to neutralize the activities of one or more serine proteinases generated by the proliferating trophoblast during the formation of the noninvasive placenta. (103 aa) |
| | LXN | Latexin. (222 aa) |
| | WFDC10A | WAP four-disulfide core domain 10A. (78 aa) |
| | SERPINB11 | Serpin family B member 11 (gene/pseudogene); Belongs to the serpin family. (392 aa) |
| | ATP5IF1 | ATPase inhibitor, mitochondrial; Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase. Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing FECH to efficiently catalyze the incorporation of iron i [...] (108 aa) |
| | SLPI | Antileukoproteinase; Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G. Modulates the inflammatory and immune responses after bacterial infection, and after infection by the intracellular parasite L.major. Down-regulates responses to bacterial lipopolysaccharide (LPS). Plays a role in regulating the activation of NF-kappa-B and inflammatory responses. Has antimicrobial activity against mycobacteria, but not against salmonella. Contributes to normal resistance against infection by M.tuberculosis. Required for normal resistance t [...] (170 aa) |
| | APLP2 | Amyloid beta precursor like protein 2. (770 aa) |
| | MGAT5 | Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase. (741 aa) |
| | SORT1 | Sortilin. (963 aa) |
| | TIMP3 | TIMP metallopeptidase inhibitor 3. (211 aa) |
| | RGS2 | Regulator of G-protein signaling 2; Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP- bound form (By similarity). It is involved in the negative regulation of the angiotensin-activated signaling pathway (By similarity). Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle (By similarity). Binds EIF [...] (212 aa) |
| | LOC106504547 | SERPIN domain-containing protein; Belongs to the serpin family. (445 aa) |
| | CMYA5 | Cardiomyopathy associated 5. (4077 aa) |
| | SERPINB12 | Serpin family B member 12; Belongs to the serpin family. (425 aa) |
| | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (398 aa) |
| | APCS | Serum amyloid P-component; Belongs to the pentraxin family. (224 aa) |
| | TGFB2 | Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (443 aa) |
| | TMED10 | Transmembrane emp24 domain-containing protein 10. (219 aa) |
| | PTGS2 | Prostaglandin G/H synthase 2. (604 aa) |
| | WFIKKN1 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (548 aa) |
| | CSTA | Cystatin-A8; This is an intracellular thiol proteinase inhibitor; Belongs to the cystatin family. (103 aa) |
| | PTPA | Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (332 aa) |
| | LOC110261265 | NTR domain-containing protein. (239 aa) |
| | ITIH4 | Inter-alpha-trypsin inhibitor heavy chain H4; Type II acute-phase protein (APP) involved in inflammatory responses to trauma. May also play a role in liver development or regeneration. (976 aa) |
| | RNF34 | E3 ubiquitin-protein ligase RNF34 isoform 2. (383 aa) |
| | KLRK1 | NKG2-D type II integral membrane protein; Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress- inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-exp [...] (221 aa) |
| | WFDC2 | WAP four-disulfide core domain protein 2; Broad range protease inhibitor. (123 aa) |
| | SERPINH1 | SERPIN domain-containing protein; Belongs to the serpin family. (418 aa) |
| | SPOCK1 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1. (439 aa) |
| | SERPINA4 | Serpin family A member 4; Belongs to the serpin family. (371 aa) |
| | CDKN2D | Cyclin dependent kinase inhibitor 2D. (166 aa) |
| | APOA1 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. (279 aa) |
| | LOC110261633 | SERPIN domain-containing protein; Belongs to the serpin family. (388 aa) |
| | MT3 | Metallothionein-3; Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro (By similarity); Belongs to the metallothionein superfamily. Type 1 family. (95 aa) |
| | ANXA2 | Annexin A2; Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9. (414 aa) |
| | BOD1L1 | Biorientation of chromosomes in cell division protein 1-like 1. (2994 aa) |
| | PAX2 | Paired box 2. (416 aa) |
| | ARFGEF1 | ADP ribosylation factor guanine nucleotide exchange factor 1. (1849 aa) |
| | AMOT | Angiomotin isoform X1. (1088 aa) |
| | SRC | Tyrosine-protein kinase. (559 aa) |
| | WFDC9 | WAP four-disulfide core domain 9. (88 aa) |
| | WFDC3 | WAP domain-containing protein. (94 aa) |
| | INTS1 | Integrator complex subunit 1. (2191 aa) |
| | PPP1R35 | Protein phosphatase 1 regulatory subunit 35. (268 aa) |
| | CRIM1 | Cysteine rich transmembrane BMP regulator 1. (1031 aa) |
| | BIRC6 | Baculoviral IAP repeat containing 6. (4843 aa) |
| | FKBP1B | Peptidylprolyl isomerase. (108 aa) |
| | SFRP2 | Uncharacterized protein. (294 aa) |
| | CSN2 | Beta-casein; Important role in determination of the surface properties of the casein micelles. (231 aa) |
| | SERPINE3 | Serpin family E member 3; Belongs to the serpin family. (408 aa) |
| | LRCH1 | Leucine rich repeats and calponin homology domain containing 1. (771 aa) |
| | PCID2 | PCI domain-containing protein 2 isoform X1. (399 aa) |
| | SH3RF1 | E3 ubiquitin-protein ligase SH3RF1 isoform X1. (849 aa) |
| | SPOCK3 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3. (436 aa) |
| | FZD10 | Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa) |
| | TMEM132B | Uncharacterized protein. (591 aa) |
| | SERPIND1 | Serpin family D member 1; Belongs to the serpin family. (517 aa) |
| | PRDX3 | Thioredoxin domain-containing protein. (261 aa) |
| | UCHL5 | Ubiquitin carboxyl-terminal hydrolase isozyme L5; Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1 (By similarity). (327 aa) |
| | SPINK4 | Serine protease inhibitor Kazal-type 4; Inhibits the glucose-induced insulin secretion from perfused pancreas; also plays a role in the immune system. Does not inhibit trypsin. (86 aa) |
| | ITIH2 | Inter-alpha-trypsin inhibitor heavy chain H2; May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. (923 aa) |
| | ITIH5 | Inter-alpha-trypsin inhibitor heavy chain 5. (944 aa) |
| | LOC100736951 | Uncharacterized protein. (177 aa) |
| | PTX3 | Pentraxin-related protein PTX3. (382 aa) |
| | SERPINI2 | Serpin family I member 2; Belongs to the serpin family. (405 aa) |
| | FETUB | Fetuin-B isoform 1. (377 aa) |
| | HRG | Uncharacterized protein. (561 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase. (524 aa) |
| | APP | Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (756 aa) |
| | DDX3X | ATP-dependent RNA helicase DDX3X isoform 1; Belongs to the DEAD box helicase family. (662 aa) |
| | TIMP1 | Metalloproteinase inhibitor 1; Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling (By similarity). (207 aa) |
| | SERPINA7 | Thyroxine-binding globulin; Major thyroid hormone transport protein in serum. Belongs to the serpin family. (420 aa) |
| | PLXNB3 | Plexin B3. (1894 aa) |
| | CST6 | Cystatin E/M; Belongs to the cystatin family. (149 aa) |
| | PRDX5 | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (170 aa) |
| | SERPING1 | Plasma protease C1 inhibitor isoform X1; Belongs to the serpin family. (491 aa) |
| | CRY2 | Cryptochrome circadian regulator 2. (615 aa) |
