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| | RNF165 | Ring finger protein 165. (365 aa) |
| | HOXC13 | Homeobox C13. (332 aa) |
| | TULP3 | TUB like protein 3; Belongs to the TUB family. (472 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (463 aa) |
| | TMEM231 | Transmembrane protein 231. (318 aa) |
| | SALL1 | Spalt like transcription factor 1. (1326 aa) |
| | MEGF8 | Multiple EGF like domains 8. (2789 aa) |
| | BAX | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; Belongs to the Gfo/Idh/MocA family. (480 aa) |
| | ECE1 | Endothelin converting enzyme 1. (771 aa) |
| | KDF1 | Keratinocyte differentiation factor 1. (398 aa) |
| | TBC1D32 | Protein broad-minded isoform X1. (1300 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog 4; Common SMAD (co-SMAD) is the coactivator and mediator of signal transduction by TGF-beta (transforming growth factor). Component of the heterotrimeric SMAD2/SMAD3-SMAD4 complex that forms in the nucleus and is required for the TGF-mediated signaling. Promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. Component of the multimeric SMAD3/SMAD4/JUN/FOS complex which forms at the AP1 promoter site; required for synergistic transcriptional activity in r [...] (552 aa) |
| | RAX | Retina and anterior neural fold homeobox. (346 aa) |
| | BMP4 | Bone morphogenetic protein 4. (409 aa) |
| | EXT1 | Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa) |
| | FZD6 | Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (711 aa) |
| | OSR2 | Odd-skipped related transciption factor 2. (312 aa) |
| | SULF1 | Sulfatase 1. (1108 aa) |
| | CHD7 | Chromodomain helicase DNA binding protein 7. (2863 aa) |
| | CRABP2 | FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa) |
| | NOTCH2 | Neurogenic locus notch homolog protein 2 isoform 1 preproprotein. (2471 aa) |
| | RSPO4 | R-spondin 4. (235 aa) |
| | BMP7 | Bone morphogenetic protein 7. (650 aa) |
| | IFT140 | Intraflagellar transport 140. (1477 aa) |
| | BCL2L11 | Uncharacterized protein. (433 aa) |
| | CYP26B1 | Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa) |
| | PKDCC | Protein kinase domain containing, cytoplasmic. (493 aa) |
| | MSX1 | Homeobox domain-containing protein. (303 aa) |
| | SFRP2 | Uncharacterized protein. (294 aa) |
| | FREM2 | FRAS1 related extracellular matrix 2. (3174 aa) |
| | TBX3 | T-box transcription factor TBX3 isoform 2. (745 aa) |
| | TBX5 | T-box transcription factor 5. (535 aa) |
| | HNF1A | Hepatocyte nuclear factor 1-alpha isoform 2. (631 aa) |
| | KREMEN1 | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (464 aa) |
| | ATRX | ATRX chromatin remodeler. (2486 aa) |
| | ZIC3 | Zic family member 3. (467 aa) |
| | FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) |
| | LRP5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1614 aa) |
| | COMP | Cartilage oligomeric matrix protein. (756 aa) |
| | C2CD3 | C2 domain containing 3 centriole elongation regulator. (2353 aa) |
| | MEOX2 | Homeobox domain-containing protein. (303 aa) |
| | FLVCR1 | Feline leukemia virus subgroup C receptor-related protein 1. (559 aa) |
| | EN1 | Homeobox protein engrailed-like. (367 aa) |
| | HOXD13 | Homeobox protein Hox-D13. (341 aa) |
| | HOXD12 | Homeobox protein Hox-D12. (270 aa) |
| | HOXD10 | Homeobox protein Hox-D10. (410 aa) |
| | HOXD9 | Homeobox D9. (351 aa) |
| | IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (454 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (440 aa) |
| | HOXA11 | Homeobox protein Hox-A11. (317 aa) |
| | GLI3 | GLI family zinc finger 3. (1586 aa) |
| | CPLANE1 | Ciliogenesis and planar polarity effector 1. (3098 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa) |
| | SOX9 | Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (511 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1517 aa) |
| | MKS1 | MKS transition zone complex subunit 1. (557 aa) |
| | FOXN1 | Forkhead box N1. (671 aa) |
| | IFT80 | Intraflagellar transport 80. (767 aa) |
| | SHOX2 | Short stature homeobox 2. (321 aa) |
| | PLXNA2 | Plexin A2. (1937 aa) |
| | TBX2 | T-box 2 protein. (714 aa) |
| | SEMA3C | Semaphorin-3C isoform 2; Belongs to the semaphorin family. (751 aa) |
| | HOXA9 | Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (272 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (491 aa) |
| | TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (217 aa) |
| | EVX2 | Even-skipped homeobox 2. (474 aa) |
| | GDF5 | Growth differentiation factor 5. (499 aa) |
| | MED31 | Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (131 aa) |
| | WDR19 | WD repeat domain 19. (1342 aa) |
| | HOXC11 | Homeobox C11. (304 aa) |
| | HOXA13 | Homeobox A13. (388 aa) |
| | HOXC10 | Homeobox C10. (342 aa) |
| | TBX4 | Uncharacterized protein. (549 aa) |
| | SLC7A11 | Solute carrier family 7 member 11. (515 aa) |
| | TMEM107 | Transmembrane protein 107 isoform 2. (140 aa) |
| | PTCH1 | Protein patched homolog 1 isoform L. (1452 aa) |
| | GNAS | Guanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2. (1045 aa) |
| | GPC3 | Glypican-3 isoform 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (579 aa) |
| | ITGA6 | Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1072 aa) |
| | CTNNB1 | Catenin beta 1. (808 aa) |
| | RSPO3 | Uncharacterized protein. (280 aa) |
| | RPGRIP1L | Protein fantom isoform X1. (1270 aa) |
| | ALDH1A2 | Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (527 aa) |
| | RSPO2 | Uncharacterized protein. (242 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1085 aa) |
| | GRHL2 | Grainyhead like transcription factor 2. (626 aa) |
| | RUNX2 | Runt-related transcription factor 2 isoform a. (625 aa) |
| | ITGB4 | Integrin beta. (1814 aa) |
| | FRAS1 | Fraser extracellular matrix complex subunit 1. (4013 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa) |
| | FBN2 | Fibrillin 2. (2910 aa) |
| | MAP3K20 | Mitogen-activated protein kinase kinase kinase 20. (799 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa) |
| | RECK | Reversion-inducing cysteine-rich protein with Kazal motifs isoform 1. (971 aa) |
| | SMOC1 | SPARC related modular calcium binding 1. (469 aa) |
| | FGF9 | Fibroblast growth factor 9; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors (By similarity). (228 aa) |
| | ALX3 | ALX homeobox 3. (362 aa) |
| | DLX6 | Distal-less homeobox 6. (333 aa) |
| | RC3H2 | Ring finger and CCCH-type domains 2. (1192 aa) |
| | LNPK | Lunapark, ER junction formation factor. (429 aa) |
| | LMBR1 | Limb region 1 protein homolog isoform b; Belongs to the LIMR family. (490 aa) |
| | PCSK5 | Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1886 aa) |
| | HAND2 | Heart-and neural crest derivatives-expressed protein 2. (217 aa) |
| | INTU | Inturned planar cell polarity protein. (937 aa) |
| | B9D1 | B9 domain containing 1. (204 aa) |
| | NIPBL | Nipped-B protein. (2804 aa) |
| | CHST11 | Carbohydrate sulfotransferase. (352 aa) |
| | NOG | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa) |
| | FMN1 | Formin 1. (1195 aa) |
| | TFAP2A | Transcription factor AP-2 alpha. (439 aa) |
| | SP8 | Sp8 transcription factor. (504 aa) |
| | SCX | Basic helix-loop-helix transcription factor scleraxis. (310 aa) |
| | PITX2 | Homeobox protein. (326 aa) |
| | NOTCH1 | Neurogenic locus notch homolog protein 1 preproprotein. (2560 aa) |
| | IFT52 | Intraflagellar transport protein 52 homolog isoform X1. (446 aa) |
| | SLC39A1 | Solute carrier family 39 member 1. (481 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (453 aa) |
| | KREMEN2 | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (461 aa) |
| | GNA12 | G protein subunit alpha 12. (382 aa) |
| | DLX5 | Homeobox protein DLX-5. (290 aa) |
| | LRP4 | LDL receptor related protein 4. (1918 aa) |
| | IRF6 | Interferon regulatory factor 6. (467 aa) |
| | PIAS4 | Protein inhibitor of activated STAT 4. (566 aa) |
| | IMPAD1 | Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase; Exhibits 3'-nucleotidase activity toward adenosine 3',5'- bisphosphate (PAP), namely hydrolyzes adenosine 3',5'-bisphosphate into adenosine 5'-monophosphate (AMP) and a phosphate. May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3',5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation. Has no activity toward 3'-phosphoadenosine 5'-phosphosulfate (PAPS) or inositol phosphate (IP) substrates including I(1)P, I(1,4)P2, [...] (359 aa) |
| | BMPR1A | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | TFAP2B | Transcription factor AP-2 beta. (469 aa) |
| | GREM1 | Gremlin 1, DAN family BMP antagonist. (240 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | PRRX1 | Paired mesoderm homeobox protein 1 isoform pmx-1b. (245 aa) |
| | ALX4 | ALX homeobox 4. (406 aa) |
| | COL2A1 | Collagen type II alpha 1 chain. (1486 aa) |
| | OSR1 | Odd-skipped related transcription factor 1. (267 aa) |
| | RARA | Retinoic acid receptor alpha isoform X1. (462 aa) |
| | ZNF219 | Zinc finger protein 219. (716 aa) |
| | RDH10 | Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa) |
| | PITX1 | Homeobox protein. (314 aa) |
| | SP9 | Sp9 transcription factor. (485 aa) |
| | ZBTB16 | Zinc finger and BTB domain containing 16. (673 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (429 aa) |
| | COL3A1 | Collagen alpha-1(III) chain preproprotein. (1471 aa) |
| | BAK1 | Uncharacterized protein. (266 aa) |
| | RARG | Retinoic acid receptor gamma. (554 aa) |
