(11 nodes) Embryonic skeletal joint morphogenesis network (Sus scrofa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BMP4	Bone morphogenetic protein 4. (409 aa)
	HYAL1	Hyaluronidase-1; May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth (By similarity); Belongs to the glycosyl hydrolase 56 family. (650 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	COL2A1	Collagen type II alpha 1 chain. (1486 aa)
	OSR1	Odd-skipped related transcription factor 1. (267 aa)
	CTNNB1	Catenin beta 1. (808 aa)
	HOXC11	Homeobox C11. (304 aa)
	SHOX2	Short stature homeobox 2. (321 aa)
	HOXA11	Homeobox protein Hox-A11. (317 aa)
	BMP7	Bone morphogenetic protein 7. (650 aa)
	OSR2	Odd-skipped related transciption factor 2. (312 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	BMP7	ENSSSCP00000005423	ENSSSCP00000007993	Bone morphogenetic protein 4.	Bone morphogenetic protein 7.	0.842
BMP4	COL2A1	ENSSSCP00000005423	ENSSSCP00000036099	Bone morphogenetic protein 4.	Collagen type II alpha 1 chain.	0.439
BMP4	CTNNB1	ENSSSCP00000005423	ENSSSCP00000031836	Bone morphogenetic protein 4.	Catenin beta 1.	0.604
BMP4	NOG	ENSSSCP00000005423	ENSSSCP00000053671	Bone morphogenetic protein 4.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.998
BMP4	SHOX2	ENSSSCP00000005423	ENSSSCP00000020186	Bone morphogenetic protein 4.	Short stature homeobox 2.	0.446
BMP7	BMP4	ENSSSCP00000007993	ENSSSCP00000005423	Bone morphogenetic protein 7.	Bone morphogenetic protein 4.	0.842
BMP7	COL2A1	ENSSSCP00000007993	ENSSSCP00000036099	Bone morphogenetic protein 7.	Collagen type II alpha 1 chain.	0.609
BMP7	CTNNB1	ENSSSCP00000007993	ENSSSCP00000031836	Bone morphogenetic protein 7.	Catenin beta 1.	0.507
BMP7	NOG	ENSSSCP00000007993	ENSSSCP00000053671	Bone morphogenetic protein 7.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.955
COL2A1	BMP4	ENSSSCP00000036099	ENSSSCP00000005423	Collagen type II alpha 1 chain.	Bone morphogenetic protein 4.	0.439
COL2A1	BMP7	ENSSSCP00000036099	ENSSSCP00000007993	Collagen type II alpha 1 chain.	Bone morphogenetic protein 7.	0.609
CTNNB1	BMP4	ENSSSCP00000031836	ENSSSCP00000005423	Catenin beta 1.	Bone morphogenetic protein 4.	0.604
CTNNB1	BMP7	ENSSSCP00000031836	ENSSSCP00000007993	Catenin beta 1.	Bone morphogenetic protein 7.	0.507
CTNNB1	NOG	ENSSSCP00000031836	ENSSSCP00000053671	Catenin beta 1.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.520
NOG	BMP4	ENSSSCP00000053671	ENSSSCP00000005423	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	Bone morphogenetic protein 4.	0.998
NOG	BMP7	ENSSSCP00000053671	ENSSSCP00000007993	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	Bone morphogenetic protein 7.	0.955
NOG	CTNNB1	ENSSSCP00000053671	ENSSSCP00000031836	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	Catenin beta 1.	0.520
SHOX2	BMP4	ENSSSCP00000020186	ENSSSCP00000005423	Short stature homeobox 2.	Bone morphogenetic protein 4.	0.446