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| | TAL1 | TAL bHLH transcription factor 1, erythroid differentiation factor. (331 aa) |
| | COL2A1 | Collagen type II alpha 1 chain. (1486 aa) |
| | TMEM38B | Trimeric intracellular cation channel type B. (290 aa) |
| | RARA | Retinoic acid receptor alpha isoform X1. (462 aa) |
| | ATG9A | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (871 aa) |
| | SP5 | Sp5 transcription factor. (397 aa) |
| | MPIG6B | Ig-like domain-containing protein. (328 aa) |
| | RAB23 | RAB23, member RAS oncogene family. (206 aa) |
| | NOTUM | Notum, palmitoleoyl-protein carboxylesterase. (570 aa) |
| | PAFAH1B1 | Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa) |
| | SERPINH1 | SERPIN domain-containing protein; Belongs to the serpin family. (418 aa) |
| | COL3A1 | Collagen alpha-1(III) chain preproprotein. (1471 aa) |
| | SMAD5 | Mothers against decapentaplegic homolog. (465 aa) |
| | SPNS2 | Sphingolipid transporter 2. (561 aa) |
| | SMAD1 | Mothers against decapentaplegic homolog. (465 aa) |
| | RARG | Retinoic acid receptor gamma. (554 aa) |
| | PPIB | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (202 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | ANXA2 | Annexin A2; Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9. (414 aa) |
| | GPR68 | G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (370 aa) |
| | PAPSS2 | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 isoform b. (620 aa) |
| | SRC | Tyrosine-protein kinase. (559 aa) |
| | BGN | Biglycan; May be involved in collagen fiber assembly. (338 aa) |
| | AMER1 | APC membrane recruitment protein 1. (1108 aa) |
| | SEMA4D | Semaphorin-4D isoform X1; Belongs to the semaphorin family. (865 aa) |
| | GNAS | Guanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2. (1045 aa) |
| | PLS3 | Plastin 3. (589 aa) |
| | TRIM45 | Tripartite motif-containing protein 45 isoform 1. (580 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa) |
| | DCHS1 | Dachsous cadherin-related 1. (3294 aa) |
| | TMEM107 | Transmembrane protein 107 isoform 2. (140 aa) |
| | I3LSZ9_PIG | Uncharacterized protein. (169 aa) |
| | LTF | Lactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity. Shows a preferential cleavage at -Arg-Ser-Arg-Arg-|- and -Arg-Arg-Ser-Arg-|-, and of Z-Phe-Arg-|-aminomethylcoumarin sites. (704 aa) |
| | ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa) |
| | ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif 12. (1598 aa) |
| | GLG1 | Golgi glycoprotein 1. (1210 aa) |
| | CCDC154 | Coiled-coil domain containing 154. (524 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (396 aa) |
| | TTC9 | TPR_REGION domain-containing protein. (391 aa) |
| | BMPR1B | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | THPO | Thrombopoietin; Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. (477 aa) |
| | WASF2 | Wiskott-Aldrich syndrome protein family member 2 isoform 2. (498 aa) |
| | BNC2 | Basonuclin 2. (1085 aa) |
| | LEPR | Leptin receptor; Receptor for hormone LEP/leptin (By similarity). On ligand binding, mediates LEP central and peripheral effects through the activation of different signaling pathways such as JAK2/STAT3 and MAPK cascade/FOS. In the hypothalamus, LEP acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal metabolism, influences reproductiv [...] (1165 aa) |
| | MMP14 | Matrix metalloproteinase-14; Endopeptidase that degrades various components of the extracellular matrix, such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15 in association with pro-MMP2. Involved in the formation of the fibrovascular tissues in association with pro-MMP2. Cleaves ADGRB1 to release vasculostatin-40 which i [...] (606 aa) |
| | NPPC | C-type natriuretic peptide; Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Specifically binds and stimulates the cGMP production of the NPR2 receptor. Binds the clearance receptor NPR3 (By similarity). (126 aa) |
| | ECM1 | Extracellular matrix protein 1. (559 aa) |
| | I3LA07_PIG | Uncharacterized protein. (398 aa) |
| | EP300 | E1A binding protein p300. (2420 aa) |
| | SHOX2 | Short stature homeobox 2. (321 aa) |
| | I3L7W9_PIG | Uncharacterized protein. (373 aa) |
| | IFT80 | Intraflagellar transport 80. (767 aa) |
| | P3H1 | Prolyl 3-hydroxylase 1 isoform 1. (698 aa) |
| | MATN1 | Matrilin 1. (496 aa) |
| | HOXB4 | Homeobox B4. (278 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1517 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (339 aa) |
| | SOX9 | Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (511 aa) |
| | ANXA6 | Annexin. (672 aa) |
| | RANBP3L | RAN binding protein 3 like. (485 aa) |
| | GLI3 | GLI family zinc finger 3. (1586 aa) |
| | SNX10 | Sorting nexin-10 isoform 1. (200 aa) |
| | HOXA11 | Homeobox protein Hox-A11. (317 aa) |
| | IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (454 aa) |
| | PAPPA2 | Pappalysin 2. (1790 aa) |
| | MMP13 | Matrix metallopeptidase 13. (470 aa) |
| | SCUBE2 | CUB domain-containing protein. (539 aa) |
| | CDX1 | Caudal type homeobox 1. (311 aa) |
| | NEUROG1 | Neurogenin 1. (246 aa) |
| | MEF2C | Myocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...] (483 aa) |
| | COMP | Cartilage oligomeric matrix protein. (756 aa) |
| | EXT2 | Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (688 aa) |
| | LRP5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1614 aa) |
| | FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) |
| | BBX | BBX high mobility group box domain containing. (966 aa) |
| | PLXNB1 | Plexin B1. (2133 aa) |
| | PIP4K2A | Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha; Catalyzes the phosphorylation of phosphatidylinositol 5- phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation. May negatively regulate insulin-stimulated glucose uptake by lowering the levels of [...] (442 aa) |
| | ABI1 | Abl interactor 1 isoform b. (481 aa) |
| | SH2B3 | SH2B adaptor protein 3. (600 aa) |
| | TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (319 aa) |
| | MSX1 | Homeobox domain-containing protein. (303 aa) |
| | NSD2 | Histone-lysine N-methyltransferase NSD2 isoform 1. (1338 aa) |
| | CYP26B1 | Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa) |
| | SBDS | Ribosome maturation protein SBDS. (250 aa) |
| | SULF2 | Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (906 aa) |
| | ASXL1 | ASXL transcriptional regulator 1. (1542 aa) |
| | PAX1 | Paired box 1. (454 aa) |
| | LOC100517735 | Hexosyltransferase. (384 aa) |
| | BGLAP | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. (100 aa) |
| | DDR2 | Discoidin domain receptor tyrosine kinase 2. (866 aa) |
| | SULF1 | Sulfatase 1. (1108 aa) |
| | OSR2 | Odd-skipped related transciption factor 2. (312 aa) |
| | EXT1 | Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa) |
| | MIGA2 | Mitoguardin 2. (592 aa) |
| | BMP4 | Bone morphogenetic protein 4. (409 aa) |
| | GJA1 | Gap junction alpha-1 protein; Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli a [...] (382 aa) |
| | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa) |
| | DHRS3 | Short-chain dehydrogenase/reductase 3 isoform 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa) |
| | MEGF8 | Multiple EGF like domains 8. (2789 aa) |
| | SRF | Serum response factor. (512 aa) |
| | EPYC | Epiphycan. (320 aa) |
| | TULP3 | TUB like protein 3; Belongs to the TUB family. (472 aa) |
| | NAB2 | NGFI-A binding protein 2. (525 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | COL13A1 | Collagen type XIII alpha 1 chain. (726 aa) |
| | ENSSSCP00000073689 | annotation not available (469 aa) |
| | ACTN3 | Actinin alpha 3 (gene/pseudogene). (931 aa) |
| | VPS33B | Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (650 aa) |
| | PHOSPHO1 | Uncharacterized protein. (465 aa) |
| | A0A5G2R4X1_PIG | Uncharacterized protein. (88 aa) |
| | RUNX2 | Runt-related transcription factor 2 isoform a. (625 aa) |
| | A0A5G2QZ07_PIG | GRIP domain-containing protein. (469 aa) |
| | ENSSSCP00000069602 | annotation not available (97 aa) |
| | PHOSPHO2 | Pyridoxal phosphate phosphatase PHOSPHO2. (241 aa) |
| | SLC10A7 | Sodium/bile acid cotransporter; Does not show transport activity towards bile acids or steroid sulfates; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. (359 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa) |
| | KIT | Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (975 aa) |
| | SH3PXD2B | SH3 and PX domains 2B. (958 aa) |
| | COL1A1 | Collagen type I alpha 1 chain. (1477 aa) |
| | TGM2 | Transglutaminase 2. (696 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) |
| | A0A5G2RF62_PIG | Uncharacterized protein. (97 aa) |
| | TRPV4 | Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (924 aa) |
| | A0A5G2QET8_PIG | GRIP domain-containing protein. (461 aa) |
| | A0A5G2RMB4_PIG | GRIP domain-containing protein. (469 aa) |
| | ALPL | Alkaline phosphatase. (834 aa) |
| | LTBP3 | Latent transforming growth factor beta binding protein 3. (1332 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (192 aa) |
| | LRRC17 | Leucine rich repeat containing 17. (438 aa) |
| | BMP6 | TGF_BETA_2 domain-containing protein. (537 aa) |
| | EBP | Emopamil binding protein (Sterol isomerase). (230 aa) |
| | FREM1 | FRAS1 related extracellular matrix 1. (2182 aa) |
| | ZNF385A | Zinc finger protein 385A. (406 aa) |
| | AXIN2 | Axin-2. (843 aa) |
| | TIFAB | TIFA inhibitor. (197 aa) |
| | FOXN3 | Forkhead box protein N3; Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints) (By similarity). (485 aa) |
| | IFITM5 | Interferon induced transmembrane protein 5. (133 aa) |
| | TFAP2A | Transcription factor AP-2 alpha. (439 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | NPR2 | Guanylate cyclase. (1094 aa) |
| | SCX | Basic helix-loop-helix transcription factor scleraxis. (310 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (442 aa) |
| | PITX2 | Homeobox protein. (326 aa) |
| | EVC | Ellis-van Creveld syndrome protein isoform 2. (991 aa) |
| | CCN4 | WNT1-inducible-signaling pathway protein 1 isoform X1. (371 aa) |
| | VKORC1 | Vitamin K epoxide reductase complex subunit 1. (163 aa) |
| | ZFPM1 | Zinc finger protein, FOG family member 1. (965 aa) |
| | TBXT | T-box transcription factor T. (435 aa) |
| | A0A287AXH2_PIG | Uncharacterized protein. (284 aa) |
| | SMPD3 | Sphingomyelin phosphodiesterase 3. (656 aa) |
| | CSGALNACT1 | Hexosyltransferase. (525 aa) |
| | CBS | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (611 aa) |
| | RHOA | Transforming protein RhoA isoform 1. (193 aa) |
| | PEX7 | Peroxisomal biogenesis factor 7. (308 aa) |
| | OGN | Osteoglycin/mimecan. (298 aa) |
| | FOXP1 | Forkhead box P1. (692 aa) |
| | MMP16 | Matrix metalloproteinase-16. (607 aa) |
| | THBS3 | Thrombospondin-3 isoform 1. (973 aa) |
| | SLC38A10 | Solute carrier family 38 member 10. (1048 aa) |
| | DLX5 | Homeobox protein DLX-5. (290 aa) |
| | MEF2D | Myocyte enhancer factor 2D. (531 aa) |
| | INSIG2 | Insulin-induced gene 2 protein; Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins (SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Seems to regulate the ubiquitin-mediated proteasomal degradation of HMGCR (By similarity). (225 aa) |
| | IMPAD1 | Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase; Exhibits 3'-nucleotidase activity toward adenosine 3',5'- bisphosphate (PAP), namely hydrolyzes adenosine 3',5'-bisphosphate into adenosine 5'-monophosphate (AMP) and a phosphate. May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3',5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation. Has no activity toward 3'-phosphoadenosine 5'-phosphosulfate (PAPS) or inositol phosphate (IP) substrates including I(1)P, I(1,4)P2, [...] (359 aa) |
| | MYOC | Myocilin. (489 aa) |
| | LRRK1 | Leucine rich repeat kinase 1. (2030 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1092 aa) |
| | MEIS1 | Homeobox protein Meis1. (465 aa) |
| | GP9 | Glycoprotein IX platelet. (173 aa) |
| | OSTN | Musclin. (132 aa) |
| | ATP6AP1 | ATPase H+ transporting accessory protein 1. (469 aa) |
| | CHAD | Chondroadherin. (359 aa) |
| | SFRP4 | Secreted frizzled-related protein 4. (346 aa) |
| | TRIP11 | Thyroid hormone receptor interactor 11. (1974 aa) |
| | BMP2 | Bone morphogenetic protein 2 preproprotein. (395 aa) |
| | FLI1 | Fli-1 proto-oncogene, ETS transcription factor. (480 aa) |
| | INSIG1 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (308 aa) |
| | PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (612 aa) |
