STRINGSTRING
AXIN2 AXIN2 SCUBE2 SCUBE2 MMP13 MMP13 IHH IHH HOXA11 HOXA11 ANXA6 ANXA6 SOX9 SOX9 MATN1 MATN1 IFT80 IFT80 SHOX2 SHOX2 NPPC NPPC ZMPSTE24 ZMPSTE24 RARG RARG SERPINH1 SERPINH1 RARA RARA COL2A1 COL2A1 TRIP11 TRIP11 THBS3 THBS3 CBS CBS SMPD3 SMPD3 ENSSSCP00000073689 ENSSSCP00000073689 A0A5G2R4X1_PIG A0A5G2R4X1_PIG A0A5G2QZ07_PIG A0A5G2QZ07_PIG ENSSSCP00000069602 ENSSSCP00000069602 COL1A1 COL1A1 A0A5G2RF62_PIG A0A5G2RF62_PIG TRPV4 TRPV4 A0A5G2QET8_PIG A0A5G2QET8_PIG A0A5G2RMB4_PIG A0A5G2RMB4_PIG ATF2 ATF2 EXT1 EXT1 COMP COMP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AXIN2Axin-2. (843 aa)
SCUBE2CUB domain-containing protein. (539 aa)
MMP13Matrix metallopeptidase 13. (470 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (454 aa)
HOXA11Homeobox protein Hox-A11. (317 aa)
ANXA6Annexin. (672 aa)
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (511 aa)
MATN1Matrilin 1. (496 aa)
IFT80Intraflagellar transport 80. (767 aa)
SHOX2Short stature homeobox 2. (321 aa)
NPPCC-type natriuretic peptide; Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Specifically binds and stimulates the cGMP production of the NPR2 receptor. Binds the clearance receptor NPR3 (By similarity). (126 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
RARGRetinoic acid receptor gamma. (554 aa)
SERPINH1SERPIN domain-containing protein; Belongs to the serpin family. (418 aa)
RARARetinoic acid receptor alpha isoform X1. (462 aa)
COL2A1Collagen type II alpha 1 chain. (1486 aa)
TRIP11Thyroid hormone receptor interactor 11. (1974 aa)
THBS3Thrombospondin-3 isoform 1. (973 aa)
CBSCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (611 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (656 aa)
ENSSSCP00000073689annotation not available (469 aa)
A0A5G2R4X1_PIGUncharacterized protein. (88 aa)
A0A5G2QZ07_PIGGRIP domain-containing protein. (469 aa)
ENSSSCP00000069602annotation not available (97 aa)
COL1A1Collagen type I alpha 1 chain. (1477 aa)
A0A5G2RF62_PIGUncharacterized protein. (97 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (924 aa)
A0A5G2QET8_PIGGRIP domain-containing protein. (461 aa)
A0A5G2RMB4_PIGGRIP domain-containing protein. (469 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
COMPCartilage oligomeric matrix protein. (756 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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