STRINGSTRING
RUVBL1 RUVBL1 NFRKB NFRKB NUCKS1 NUCKS1 INO80C INO80C INO80D INO80D SELENOK SELENOK INO80E INO80E YY1 YY1 MCRS1 MCRS1 RUVBL2 RUVBL2 TFPT TFPT INO80 INO80 ACTR5 ACTR5 INO80B INO80B UCHL5 UCHL5 ACTR8 ACTR8 ACTL6A ACTL6A POT1 POT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
NFRKBNuclear factor related to kappaB binding protein. (1333 aa)
NUCKS1Nuclear casein kinase and cyclin dependent kinase substrate 1. (250 aa)
INO80CINO80 complex subunit C. (192 aa)
INO80DINO80 complex subunit D. (1028 aa)
SELENOKSelenoprotein K; Required for Ca(2+) flux in immune cells and plays a role in T-cell proliferation and in T-cell and neutrophil migration (By similarity). Involved in endoplasmic reticulum-associated degradation (ERAD) of soluble glycosylated proteins (By similarity). Required for palmitoylation and cell surface expression of CD36 and involved in macrophage uptake of low-density lipoprotein and in foam cell formation (By similarity). Together with ZDHHC6, required for palmitoylation of ITPR1 in immune cells, leading to regulate ITPR1 stability and function. Plays a role in protection o [...] (93 aa)
INO80EINO80 complex subunit E isoform 1. (244 aa)
YY1YY1 transcription factor. (438 aa)
MCRS1Microspherule protein 1. (487 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (525 aa)
TFPTTCF3 fusion partner isoform 1. (253 aa)
INO80INO80 complex ATPase subunit. (1566 aa)
ACTR5Actin-related protein 5; Belongs to the actin family. (608 aa)
INO80BINO80 complex subunit B. (356 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase isozyme L5; Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1 (By similarity). (327 aa)
ACTR8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa)
ACTL6AActin-like protein 6A isoform X1; Belongs to the actin family. (429 aa)
POT1Protection of telomeres 1. (813 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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