STRINGSTRING
AGR2 AGR2 STRA6 STRA6 GATA6 GATA6 BMP4 BMP4 SHH SHH HOXA5 HOXA5 FGF10 FGF10 FOXJ1 FOXJ1 SOX9 SOX9 ADAMTSL2 ADAMTSL2 KRAS KRAS RCN3 RCN3 AIMP2 AIMP2 SAV1 SAV1 CTNNB1 CTNNB1 NFIB NFIB YAP1 YAP1 TMEM38B TMEM38B CREB1 CREB1 ERRFI1 ERRFI1 FOXA1 FOXA1 GRHL2 GRHL2 RBBP9 RBBP9 PKD1 PKD1 PPP3R1 PPP3R1 THRB THRB MAP2K1 MAP2K1 NKX2-1 NKX2-1 KLF2 KLF2 WNT2 WNT2 SPDEF SPDEF FNDC3B FNDC3B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGR2Anterior gradient 2, protein disulphide isomerase family member. (206 aa)
STRA6Stimulated by retinoic acid 6. (666 aa)
GATA6Transcription factor GATA-6; Transcriptional activator that regulates SEMA3C and PLXNA2. May regulate genes that protect epithelial cells from bacterial infection. Involved in gene regulation specifically in the gastric epithelium. Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. (592 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (440 aa)
HOXA5Homeobox domain-containing protein. (381 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
FOXJ1Forkhead box J1. (421 aa)
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (511 aa)
ADAMTSL2ADAMTS like 2. (958 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
RCN3Reticulocalbin 3. (335 aa)
AIMP2Uncharacterized protein. (319 aa)
SAV1Salvador family WW domain containing protein 1. (433 aa)
CTNNB1Catenin beta 1. (808 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
YAP1Yes associated protein 1. (432 aa)
TMEM38BTrimeric intracellular cation channel type B. (290 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform B. (341 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (461 aa)
FOXA1Forkhead box A1. (468 aa)
GRHL2Grainyhead like transcription factor 2. (626 aa)
RBBP9RB binding protein 9, serine hydrolase. (238 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4383 aa)
PPP3R1Uncharacterized protein. (188 aa)
THRBThyroid hormone receptor beta isoform X2. (476 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
NKX2-1NK2 homeobox 1. (399 aa)
KLF2Kruppel-like factor 2. (357 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
SPDEFSAM pointed domain containing ETS transcription factor. (363 aa)
FNDC3BFibronectin type III domain containing 3B. (1178 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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