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RSPO3 | Uncharacterized protein. (280 aa) | ||||
ADM | Proadrenomedullin N-20 terminal peptide; AM and PAMP are potent hypotensive and vasodilatator agents. (188 aa) | ||||
IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (219 aa) | ||||
FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (586 aa) | ||||
GRB2 | Growth factor receptor-bound protein 2 isoform 1. (217 aa) | ||||
SPINT1 | Serine peptidase inhibitor, Kunitz type 1. (531 aa) | ||||
GCM1 | Glial cells missing transcription factor 1. (431 aa) | ||||
ST14 | Suppressor of tumorigenicity 14 protein. (856 aa) | ||||
SOCS3 | Suppressor of cytokine signaling 3. (229 aa) | ||||
GRHL2 | Grainyhead like transcription factor 2. (626 aa) | ||||
SPINT2 | Serine peptidase inhibitor, Kunitz type 2. (252 aa) |