(9 nodes) Epithelial cell proliferation involved in prostate gland development network (Sus scrofa)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

co-expression

protein homology

Your Input:
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (440 aa)
	STK11	Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (438 aa)
	WDR77	WD repeat domain 77. (342 aa)
	EAF2	ELL associated factor 2. (273 aa)
	NKX3-1	Homeobox protein Nkx-3.1 isoform 1. (247 aa)
	SERPINF1	Serpin family F member 1; Belongs to the serpin family. (433 aa)
	CDKN1B	p27Kip1. (198 aa)
	CTNNB1	Catenin beta 1. (808 aa)
	SOX9	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (511 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDKN1B	CTNNB1	ENSSSCP00000045015	ENSSSCP00000031836	p27Kip1.	Catenin beta 1.	0.464
CDKN1B	SHH	ENSSSCP00000045015	ENSSSCP00000017394	p27Kip1.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.546
CTNNB1	CDKN1B	ENSSSCP00000031836	ENSSSCP00000045015	Catenin beta 1.	p27Kip1.	0.464
CTNNB1	SHH	ENSSSCP00000031836	ENSSSCP00000017394	Catenin beta 1.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.621
CTNNB1	SOX9	ENSSSCP00000031836	ENSSSCP00000018278	Catenin beta 1.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.918
SHH	CDKN1B	ENSSSCP00000017394	ENSSSCP00000045015	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	p27Kip1.	0.546
SHH	CTNNB1	ENSSSCP00000017394	ENSSSCP00000031836	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Catenin beta 1.	0.621
SHH	SOX9	ENSSSCP00000017394	ENSSSCP00000018278	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.614
SOX9	CTNNB1	ENSSSCP00000018278	ENSSSCP00000031836	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	Catenin beta 1.	0.918
SOX9	SHH	ENSSSCP00000018278	ENSSSCP00000017394	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.614