STRINGSTRING
TBX3 TBX3 FRS2 FRS2 PROX1 PROX1 SIX1 SIX1 SIX4 SIX4 CTNNB1 CTNNB1 NRG3 NRG3 EDA EDA HDAC1 HDAC1 TBX2 TBX2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TBX3T-box transcription factor TBX3 isoform 2. (745 aa)
FRS2Fibroblast growth factor receptor substrate 2. (550 aa)
PROX1Prospero homeobox 1. (737 aa)
SIX1Six homeobox 1. (284 aa)
SIX4Homeobox domain-containing protein. (785 aa)
CTNNB1Catenin beta 1. (808 aa)
NRG3Neuregulin 3. (718 aa)
EDAEctodysplasin A; Belongs to the tumor necrosis factor family. (389 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (491 aa)
TBX2T-box 2 protein. (714 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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