STRINGSTRING
SMAD1 SMAD1 SMAD3 SMAD3 RUNX2 RUNX2 CCN1 CCN1 GDF6 GDF6 SCX SCX LOXL2 LOXL2 SOX6 SOX6 BMP10 BMP10 WNT5A WNT5A BMP2 BMP2 ZNF219 ZNF219 ZBTB16 ZBTB16 FGF18 FGF18 BMPR1B BMPR1B GDF5 GDF5 SOX9 SOX9 GLI3 GLI3 HOXA11 HOXA11 GDF2 GDF2 BMP1 BMP1 PKDCC PKDCC BMP4 BMP4 SMAD7 SMAD7 SOX5 SOX5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAD1Mothers against decapentaplegic homolog. (465 aa)
SMAD3Mothers against decapentaplegic homolog. (434 aa)
RUNX2Runt-related transcription factor 2 isoform a. (625 aa)
CCN1Cellular communication network factor 1. (382 aa)
GDF6Growth/differentiation factor 6 preproprotein. (459 aa)
SCXBasic helix-loop-helix transcription factor scleraxis. (310 aa)
LOXL2Lysyl oxidase like 2. (758 aa)
SOX6SRY-box transcription factor 6. (859 aa)
BMP10Bone morphogenetic protein 10 preproprotein. (423 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
BMP2Bone morphogenetic protein 2 preproprotein. (395 aa)
ZNF219Zinc finger protein 219. (716 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
BMPR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
GDF5Growth differentiation factor 5. (499 aa)
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (511 aa)
GLI3GLI family zinc finger 3. (1586 aa)
HOXA11Homeobox protein Hox-A11. (317 aa)
GDF2Growth differentiation factor 2. (427 aa)
BMP1Metalloendopeptidase. (987 aa)
PKDCCProtein kinase domain containing, cytoplasmic. (493 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
SOX5SRY-box transcription factor 5. (763 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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