Your Input: | |||||
CHRDL2 | Chordin like 2. (452 aa) | ||||
ECM1 | Extracellular matrix protein 1. (559 aa) | ||||
SHOX2 | Short stature homeobox 2. (321 aa) | ||||
IFT80 | Intraflagellar transport 80. (767 aa) | ||||
TAPT1 | Transmembrane anterior posterior transformation 1. (779 aa) | ||||
MATN1 | Matrilin 1. (496 aa) | ||||
HOXB3 | Homeobox B3. (430 aa) | ||||
SOX9 | Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (511 aa) | ||||
ANXA6 | Annexin. (672 aa) | ||||
GLI3 | GLI family zinc finger 3. (1586 aa) | ||||
HOXA3 | Homeobox protein Hox-A3 isoform a. (443 aa) | ||||
HOXA5 | Homeobox domain-containing protein. (381 aa) | ||||
HOXA11 | Homeobox protein Hox-A11. (317 aa) | ||||
CREB3L2 | cAMP responsive element binding protein 3 like 2. (520 aa) | ||||
SNORC | Uncharacterized protein. (121 aa) | ||||
IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (454 aa) | ||||
HOXD3 | Homeobox protein Hox-D3. (432 aa) | ||||
DLX2 | Distal-less homeobox 2. (328 aa) | ||||
MMP13 | Matrix metallopeptidase 13. (470 aa) | ||||
SCUBE2 | CUB domain-containing protein. (539 aa) | ||||
EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (542 aa) | ||||
LOX | Protein-lysine 6-oxidase, short form; Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture (By similarity); Belongs to the lysyl oxidase family. (419 aa) | ||||
ARRDC3 | Arrestin domain-containing protein 3 isoform a. (414 aa) | ||||
MEF2C | Myocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...] (483 aa) | ||||
COMP | Cartilage oligomeric matrix protein. (756 aa) | ||||
CD44 | CD44 molecule (Indian blood group). (767 aa) | ||||
EXT2 | Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (688 aa) | ||||
SLC39A13 | Zinc transporter SLC39A7; Zinc transporter, that transports Zn(2+) from the endoplasmic reticulum/Golgi apparatus to the cytosol; Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily. (372 aa) | ||||
LRP5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1614 aa) | ||||
FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) | ||||
HYAL2 | Hyaluronidase. (476 aa) | ||||
ACTA2 | Actin alpha 2, smooth muscle. (386 aa) | ||||
EBF2 | EBF transcription factor 2. (575 aa) | ||||
CNMD | Chondromodulin. (335 aa) | ||||
RB1 | RB transcriptional corepressor 1. (938 aa) | ||||
PGRMC2 | Uncharacterized protein. (91 aa) | ||||
SFRP2 | Uncharacterized protein. (294 aa) | ||||
MSX1 | Homeobox domain-containing protein. (303 aa) | ||||
CYTL1 | Cytokine like 1. (149 aa) | ||||
MATN3 | Matrilin 3. (487 aa) | ||||
SIX2 | SIX homeobox 2. (296 aa) | ||||
SULF2 | Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (906 aa) | ||||
OTOR | Otoraplin. (129 aa) | ||||
MKKS | McKusick-Kaufman syndrome. (570 aa) | ||||
LOC100517735 | Hexosyltransferase. (384 aa) | ||||
WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (392 aa) | ||||
SULF1 | Sulfatase 1. (1108 aa) | ||||
OSR2 | Odd-skipped related transciption factor 2. (312 aa) | ||||
EXT1 | Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa) | ||||
CCN3 | Cellular communication network factor 3. (398 aa) | ||||
COL5A1 | Fibrillar collagen NC1 domain-containing protein. (1918 aa) | ||||
LOC100359361 | Uncharacterized protein. (108 aa) | ||||
BMP4 | Bone morphogenetic protein 4. (409 aa) | ||||
SRF | Serum response factor. (512 aa) | ||||
PPARD | Peroxisome proliferator-activated receptor delta. (441 aa) | ||||
GPLD1 | Glycosylphosphatidylinositol specific phospholipase D1. (906 aa) | ||||
EPYC | Epiphycan. (320 aa) | ||||
WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) | ||||
ACAN | Aggrecan core protein 2; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage. (2434 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
NOG | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa) | ||||
HES5 | Hes family bHLH transcription factor 5. (226 aa) | ||||
CHST11 | Carbohydrate sulfotransferase. (352 aa) | ||||
AXIN2 | Axin-2. (843 aa) | ||||
FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (316 aa) | ||||
ZNF516 | Zinc finger protein 516. (1138 aa) | ||||
HYAL1 | Hyaluronidase-1; May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth (By similarity); Belongs to the glycosyl hydrolase 56 family. (650 aa) | ||||
LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (192 aa) | ||||
HAND2 | Heart-and neural crest derivatives-expressed protein 2. (217 aa) | ||||
LTBP3 | Latent transforming growth factor beta binding protein 3. (1332 aa) | ||||
MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa) | ||||
SPART | Spartin. (666 aa) | ||||
DDRGK1 | DDRGK domain-containing protein 1. (312 aa) | ||||
SNX19 | Sorting nexin-19 isoform X1. (1002 aa) | ||||
CSF1 | Colony stimulating factor 1. (656 aa) | ||||
COL11A2 | Collagen type XI alpha 2 chain. (1796 aa) | ||||
FGF9 | Fibroblast growth factor 9; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors (By similarity). (228 aa) | ||||
HMGA2 | Uncharacterized protein. (143 aa) | ||||
AMELX | Uncharacterized protein. (203 aa) | ||||
A0A5G2RMB4_PIG | GRIP domain-containing protein. (469 aa) | ||||
A0A5G2QET8_PIG | GRIP domain-containing protein. (461 aa) | ||||
PKD1 | Polycystin 1, transient receptor potential channel interacting. (4383 aa) | ||||
TRPV4 | Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (924 aa) | ||||
A0A5G2RF62_PIG | Uncharacterized protein. (97 aa) | ||||
MGP | Matrix Gla protein; Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation. (127 aa) | ||||
RUNX3 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (437 aa) | ||||
MYF5 | Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (253 aa) | ||||
BBS4 | Uncharacterized protein. (826 aa) | ||||
COL1A1 | Collagen type I alpha 1 chain. (1477 aa) | ||||
CCN1 | Cellular communication network factor 1. (382 aa) | ||||
TWSG1 | Twisted gastrulation BMP signaling modulator 1. (291 aa) | ||||
LOC110258854 | Otoraplin. (132 aa) | ||||
ENSSSCP00000069602 | annotation not available (97 aa) | ||||
A0A5G2QZ07_PIG | GRIP domain-containing protein. (469 aa) | ||||
RUNX2 | Runt-related transcription factor 2 isoform a. (625 aa) | ||||
BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1085 aa) | ||||
A0A5G2R4X1_PIG | Uncharacterized protein. (88 aa) | ||||
PTH1R | Parathyroid hormone/parathyroid hormone-related peptide receptor; Receptor for parathyroid hormone and for parathyroid hormone- related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 2 family. (641 aa) | ||||
ARID5B | AT-rich interaction domain 5B. (1194 aa) | ||||
SLC25A25 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (533 aa) | ||||
ENSSSCP00000073689 | annotation not available (469 aa) | ||||
HYAL3 | Hyaluronidase-3; Facilitates sperm penetration into the layer of cumulus cells surrounding the egg by digesting hyaluronic acid. Involved in induction of the acrosome reaction in the sperm. Involved in follicular atresia, the breakdown of immature ovarian follicles that are not selected to ovulate. Induces ovarian granulosa cell apoptosis, possibly via apoptotic signaling pathway involving CASP8 and CASP3 activation, and poly(ADP-ribose) polymerase (PARP) cleavage. Has no hyaluronidase activity in embryonic fibroblasts in vitro. Has no hyaluronidase activity in granulosa cells in vitro. (490 aa) | ||||
HRAS | HRas proto-oncogene, GTPase. (189 aa) | ||||
SCX | Basic helix-loop-helix transcription factor scleraxis. (310 aa) | ||||
HIF1A | Hypoxia-inducible factor 1-alpha isoform 1. (824 aa) | ||||
SNAI1 | Snail family transcriptional repressor 1. (264 aa) | ||||
NOTCH1 | Neurogenic locus notch homolog protein 1 preproprotein. (2560 aa) | ||||
XBP1 | BZIP domain-containing protein. (378 aa) | ||||
SMPD3 | Sphingomyelin phosphodiesterase 3. (656 aa) | ||||
CSGALNACT1 | Hexosyltransferase. (525 aa) | ||||
ITGB8 | Integrin beta; Belongs to the integrin beta chain family. (722 aa) | ||||
FTO | FTO_NTD domain-containing protein. (509 aa) | ||||
ARID5A | AT-rich interaction domain 5A. (846 aa) | ||||
CBS | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (611 aa) | ||||
SPTLC2 | Serine palmitoyltransferase long chain base subunit 2. (561 aa) | ||||
OGN | Osteoglycin/mimecan. (298 aa) | ||||
THBS3 | Thrombospondin-3 isoform 1. (973 aa) | ||||
EDN1 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides. Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (203 aa) | ||||
MEF2D | Myocyte enhancer factor 2D. (531 aa) | ||||
FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) | ||||
PUM2 | Pumilio RNA binding family member 2. (1072 aa) | ||||
FOXA1 | Forkhead box A1. (468 aa) | ||||
RUNX1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa) | ||||
HAND1 | Heart and neural crest derivatives expressed 1. (218 aa) | ||||
IMPAD1 | Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase; Exhibits 3'-nucleotidase activity toward adenosine 3',5'- bisphosphate (PAP), namely hydrolyzes adenosine 3',5'-bisphosphate into adenosine 5'-monophosphate (AMP) and a phosphate. May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3',5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation. Has no activity toward 3'-phosphoadenosine 5'-phosphosulfate (PAPS) or inositol phosphate (IP) substrates including I(1)P, I(1,4)P2, [...] (359 aa) | ||||
BMPR1A | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) | ||||
HOXC4 | Homeobox protein Hox-C4. (264 aa) | ||||
TRIP11 | Thyroid hormone receptor interactor 11. (1974 aa) | ||||
PRRX1 | Paired mesoderm homeobox protein 1 isoform pmx-1b. (245 aa) | ||||
DYRK1B | Dual specificity tyrosine phosphorylation regulated kinase 1B. (778 aa) | ||||
CCN2 | CCN family member 2; Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes (By similarity). Mediates heparin- and divalent cation- dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells (By similarity). Enhances fibroblast growth factor-induced DNA synthesis (By similarity). (354 aa) | ||||
DHRS7B | Dehydrogenase/reductase 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (326 aa) | ||||
BMP2 | Bone morphogenetic protein 2 preproprotein. (395 aa) | ||||
PAXIP1 | PAX interacting protein 1. (1030 aa) | ||||
COL2A1 | Collagen type II alpha 1 chain. (1486 aa) | ||||
OSR1 | Odd-skipped related transcription factor 1. (267 aa) | ||||
BBS1 | Bardet-Biedl syndrome 1 protein. (593 aa) | ||||
RARA | Retinoic acid receptor alpha isoform X1. (462 aa) | ||||
ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) | ||||
PITX1 | Homeobox protein. (314 aa) | ||||
SOX8 | SRY-box transcription factor 8. (460 aa) | ||||
RXFP1 | Relaxin family peptide receptor 1. (785 aa) | ||||
ZBTB16 | Zinc finger and BTB domain containing 16. (673 aa) | ||||
SERPINH1 | SERPIN domain-containing protein; Belongs to the serpin family. (418 aa) | ||||
VPS13B | Vacuolar protein sorting-associated protein 13B isoform X1. (4018 aa) | ||||
COL3A1 | Collagen alpha-1(III) chain preproprotein. (1471 aa) | ||||
WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa) | ||||
NFIB | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa) | ||||
MEX3C | RNA-binding E3 ubiquitin-protein ligase MEX3C. (655 aa) | ||||
SMAD5 | Mothers against decapentaplegic homolog. (465 aa) | ||||
RASAL2 | RAS protein activator like 2. (1279 aa) | ||||
SMAD1 | Mothers against decapentaplegic homolog. (465 aa) | ||||
RARG | Retinoic acid receptor gamma. (554 aa) | ||||
PPARGC1A | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha; Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis. Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism. Induces the expression of PERM1 in [...] (796 aa) | ||||
CTNNB1 | Catenin beta 1. (808 aa) | ||||
TGFB1 | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa) | ||||
IL17F | Interleukin 17F. (165 aa) | ||||
BGN | Biglycan; May be involved in collagen fiber assembly. (338 aa) | ||||
AMER1 | APC membrane recruitment protein 1. (1108 aa) | ||||
GNAS | Guanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2. (1045 aa) | ||||
ZEB1 | Zinc finger E-box binding homeobox 1. (1128 aa) | ||||
SLC39A14 | Solute carrier family 39 member 14. (531 aa) | ||||
FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa) | ||||
BMP3 | TGF_BETA_2 domain-containing protein. (719 aa) | ||||
BBS2 | Bardet-Biedl syndrome 2 protein homolog. (727 aa) | ||||
SATB2 | DNA-binding protein SATB. (733 aa) | ||||
ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa) | ||||
ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif 12. (1598 aa) | ||||
BMPR1B | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) | ||||
GDF5 | Growth differentiation factor 5. (499 aa) | ||||
SELENOM | Sep15_SelM domain-containing protein. (142 aa) | ||||
CDK4 | Cyclin-dependent kinase 4; Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. [...] (303 aa) | ||||
NPPC | C-type natriuretic peptide; Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Specifically binds and stimulates the cGMP production of the NPR2 receptor. Binds the clearance receptor NPR3 (By similarity). (126 aa) | ||||
UMODL1 | Uromodulin like 1. (1360 aa) |