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NTN1 | Netrin-1; Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion (By similarity). Involved in dorsal root ganglion axon projection towards the spinal cord (By similarity). It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involve [...] (651 aa) | ||||
VWF | Von Willebrand factor; Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet- surface receptor complex, glycoprotein Ibalpha/IX/V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma (By similarity). (2940 aa) | ||||
NTN4 | Netrin 4. (628 aa) | ||||
LUM | Lumican. (341 aa) | ||||
LOXL1 | Lysyl oxidase like 1. (591 aa) | ||||
FBLN5 | Fibulin-5 isoform X2. (461 aa) | ||||
NTN5 | Netrin-5. (499 aa) | ||||
VWA1 | Von Willebrand factor A domain containing 1. (480 aa) | ||||
LAMA3 | Laminin subunit alpha 3. (3345 aa) | ||||
ANGPTL3 | Fibrinogen C-terminal domain-containing protein. (461 aa) | ||||
SMOC2 | SPARC related modular calcium binding 2. (613 aa) | ||||
LOC100520342 | Nephrocan-like. (512 aa) | ||||
LAMA4 | Laminin subunit alpha 4. (1815 aa) | ||||
COL10A1 | Type X collagen. (675 aa) | ||||
FBN1 | Fibrillin-1; [Fibrillin-1]: Structural component of the 10-12 nm diameter microfibrils of the extracellular matrix, which conveys both structural and regulatory properties to load-bearing connective tissues. Fibrillin-1-containing microfibrils provide long-term force bearing structural support. In tissues such as the lung, blood vessels and skin, microfibrils form the periphery of the elastic fiber, acting as a scaffold for the deposition of elastin. In addition, microfibrils can occur as elastin-independent networks in tissues such as the ciliary zonule, tendon, cornea and glomerulus [...] (2871 aa) | ||||
THBS1 | Uncharacterized protein. (1170 aa) | ||||
COL15A1 | Collagen type XV alpha 1 chain. (1359 aa) | ||||
MEGF9 | Multiple EGF like domains 9. (599 aa) | ||||
ANGPTL2 | Angiopoietin-related protein 2. (493 aa) | ||||
HMCN2 | Hemicentin 2. (5047 aa) | ||||
FIBCD1 | Fibrinogen C domain containing 1. (461 aa) | ||||
LAMC3 | Laminin subunit gamma 3. (1575 aa) | ||||
COL5A1 | Fibrillar collagen NC1 domain-containing protein. (1918 aa) | ||||
PCSK6 | Proprotein convertase subtilisin/kexin type 6 isoform PACE4-AI preproprotein; Belongs to the peptidase S8 family. (965 aa) | ||||
BCAN | Brevican core protein isoform X1. (906 aa) | ||||
ANGPT4 | Angiopoietin 4. (503 aa) | ||||
GPC2 | Glypican 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (577 aa) | ||||
ZP3 | Processed zona pellucida sperm-binding protein 3; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for zona matrix formation. May not have a sperm- binding activity by itself but may increase sperm-binding activity of ZPB. (421 aa) | ||||
ZP2 | Processed zona pellucida sperm-binding protein 2; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP2 may act as a secondary sperm receptor. Belongs to the ZP domain family. ZPA subfamily. (716 aa) | ||||
NTN3 | Netrin 3. (579 aa) | ||||
OMD | Osteomodulin. (422 aa) | ||||
MATN3 | Matrilin 3. (487 aa) | ||||
IGFBP7 | Uncharacterized protein. (278 aa) | ||||
AMTN | Amelotin. (209 aa) | ||||
MMRN1 | Multimerin 1. (1220 aa) | ||||
SPARCL1 | SPARC like 1. (675 aa) | ||||
POSTN | Periostin. (836 aa) | ||||
FREM2 | FRAS1 related extracellular matrix 2. (3174 aa) | ||||
COL4A2 | Collagen type IV alpha 2 chain. (1712 aa) | ||||
ZP4 | Processed zona pellucida sperm-binding protein 4; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP4 may act as a sperm receptor. (536 aa) | ||||
NID1 | Nidogen 1. (1309 aa) | ||||
RBP3 | Retinol-binding protein 3; IRBP shuttles 11-cis and all trans retinoids between the retinol isomerase in the pigment epithelium and the visual pigments in the photoreceptor cells of the retina. (1284 aa) | ||||
LOXL4 | Lysyl oxidase like 4. (757 aa) | ||||
VWA2 | Von Willebrand factor A domain containing 2. (735 aa) | ||||
ATRNL1 | Attractin like 1. (1382 aa) | ||||
FBLN2 | Fibulin-2 isoform a. (1221 aa) | ||||
P3H2 | Prolyl 3-hydroxylase 2 isoform a. (706 aa) | ||||
ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif 5. (929 aa) | ||||
EGFL6 | EGF like domain multiple 6. (536 aa) | ||||
TIMP1 | Metalloproteinase inhibitor 1; Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling (By similarity). (207 aa) | ||||
COL4A6 | Collagen type IV alpha 6 chain. (1547 aa) | ||||
GPC4 | Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (556 aa) | ||||
F2 | Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity). (623 aa) | ||||
NAV2 | Neuron navigator 2. (2407 aa) | ||||
ANGPTL4 | Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stre [...] (412 aa) | ||||
ANGPTL6 | Angiopoietin like 6. (463 aa) | ||||
COL5A3 | Collagen type V alpha 3 chain. (1747 aa) | ||||
PODNL1 | Podocan like 1. (576 aa) | ||||
COMP | Cartilage oligomeric matrix protein. (756 aa) | ||||
VCAN | Versican. (3456 aa) | ||||
LOX | Protein-lysine 6-oxidase, short form; Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture (By similarity); Belongs to the lysyl oxidase family. (419 aa) | ||||
RELL2 | RELT like 2. (305 aa) | ||||
ANGPTL5 | Angiopoietin-related protein 5. (388 aa) | ||||
ADAMTS15 | A disintegrin and metalloproteinase with thrombospondin motifs 15 preproprotein. (950 aa) | ||||
FMOD | Fibromodulin; Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity). (376 aa) | ||||
COL1A2 | Fibrillar collagen NC1 domain-containing protein. (1135 aa) | ||||
FGL2 | Fibroleukin. (495 aa) | ||||
LAMB1 | Laminin subunit beta 1. (1785 aa) | ||||
LAMC2 | Laminin subunit gamma-2 isoform a. (1191 aa) | ||||
LAMB3 | Laminin subunit beta 3. (1172 aa) | ||||
COL4A3 | Collagen type IV alpha 3 chain. (1669 aa) | ||||
SNORC | Uncharacterized protein. (121 aa) | ||||
FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa) | ||||
MATN1 | Matrilin 1. (496 aa) | ||||
FCN2 | Ficolin-2. (429 aa) | ||||
PRG4 | Uncharacterized protein. (370 aa) | ||||
THBS4 | Thrombospondin 4. (976 aa) | ||||
VTN | Vitronectin; Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway (By similarity). (523 aa) | ||||
ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif 2. (1204 aa) | ||||
ECM1 | Extracellular matrix protein 1. (559 aa) | ||||
LRRC15 | Leucine rich repeat containing 15. (581 aa) | ||||
COCH | Cochlin isoform X2. (551 aa) | ||||
PXDN | Peroxidasin. (1529 aa) | ||||
TINAG | Tubulointerstitial nephritis antigen; Belongs to the peptidase C1 family. (476 aa) | ||||
FBN3 | Fibrillin 3. (2858 aa) | ||||
VIT | Vitrin. (656 aa) | ||||
FGG | Fibrinogen gamma chain. (454 aa) | ||||
COL6A2 | Collagen type VI alpha 2 chain. (943 aa) | ||||
SERPINE1 | Plasminogen activator inhibitor 1; Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase- type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. I [...] (401 aa) | ||||
ECM2 | Extracellular matrix protein 2. (696 aa) | ||||
SOD3 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (303 aa) | ||||
COL17A1 | Collagen type XVII alpha 1 chain. (1506 aa) | ||||
COL6A3 | Collagen type VI alpha 3 chain. (2911 aa) | ||||
ATRN | Attractin. (1416 aa) | ||||
SFRP1 | Secreted frizzled-related protein 1. (308 aa) | ||||
GPC3 | Glypican-3 isoform 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (579 aa) | ||||
FGFR2 | Fibroblast growth factor receptor. (820 aa) | ||||
TNXB | Uncharacterized protein. (4137 aa) | ||||
TGFB3 | Transforming growth factor beta-3 proprotein; Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively. Transforming growth factor beta-3: Multifunctional protein that regulates embryogenesis and cell differentiation and is required in various processes such as secondary palate development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi appa [...] (456 aa) | ||||
DLG1 | Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa) | ||||
ANGPTL1 | Angiopoietin-related protein 1 isoform X1. (502 aa) | ||||
ANXA2 | Annexin A2; Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9. (414 aa) | ||||
IMPG2 | Interphotoreceptor matrix proteoglycan 2. (1244 aa) | ||||
COL25A1 | Collagen type XXV alpha 1 chain. (695 aa) | ||||
COL3A1 | Collagen alpha-1(III) chain preproprotein. (1471 aa) | ||||
COL16A1 | Collagen alpha-1(XVI) chain isoform X2. (1624 aa) | ||||
AGRN | Agrin. (2108 aa) | ||||
EFNA5 | Ephrin A5; Belongs to the ephrin family. (228 aa) | ||||
PTPRZ1 | Protein tyrosine phosphatase receptor type Z1. (2323 aa) | ||||
TGFB2 | Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (443 aa) | ||||
COL2A1 | Collagen type II alpha 1 chain. (1486 aa) | ||||
LTBP1 | Latent transforming growth factor beta binding protein 1. (1708 aa) | ||||
FGL1 | Fibrinogen like 1. (315 aa) | ||||
TIMP3 | TIMP metallopeptidase inhibitor 3. (211 aa) | ||||
LAMA2 | Uncharacterized protein. (2070 aa) | ||||
LAMC1 | Uncharacterized protein. (1607 aa) | ||||
LAMA2-2 | Uncharacterized protein. (921 aa) | ||||
CCDC80 | Coiled-coil domain containing 80. (1016 aa) | ||||
KAZALD1 | Kazal-type serine protease inhibitor domain-containing protein 1 isoform X1. (315 aa) | ||||
MYOC | Myocilin. (489 aa) | ||||
NTNG2 | Netrin G2. (529 aa) | ||||
COL9A3 | Collagen type IX alpha 3 chain. (684 aa) | ||||
ENTPD2 | Ectonucleoside triphosphate diphosphohydrolase 2 isoform 1; Belongs to the GDA1/CD39 NTPase family. (495 aa) | ||||
HSPG2 | Heparan sulfate proteoglycan 2. (4346 aa) | ||||
COL20A1 | Uncharacterized protein. (1338 aa) | ||||
GPC5 | Glypican 5; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (571 aa) | ||||
GPC6 | Glypican-6 isoform X1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (555 aa) | ||||
THBS3 | Thrombospondin-3 isoform 1. (973 aa) | ||||
NID2 | Nidogen 2. (1348 aa) | ||||
FBLN1 | Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (819 aa) | ||||
ANGPTL7 | Angiopoietin-related protein 7. (344 aa) | ||||
LOXL2 | Lysyl oxidase like 2. (758 aa) | ||||
EFEMP1 | EGF containing fibulin extracellular matrix protein 1. (512 aa) | ||||
LOC110259263 | C-type lectin domain-containing protein. (172 aa) | ||||
GPC1 | Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (559 aa) | ||||
COL4A5 | Collagen type IV alpha 5 chain. (1689 aa) | ||||
TNC | Tenascin; Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha- V/beta-6. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells (By similarity). Belongs to the tenascin family. (2420 aa) | ||||
LAMB2 | Laminin subunit beta-2. (1881 aa) | ||||
ADAMTSL4 | ADAMTS like 4. (1079 aa) | ||||
ELN | Elastin. (674 aa) | ||||
MATN2 | Matrilin 2. (956 aa) | ||||
SERPINE2 | SERPIN domain-containing protein; Belongs to the serpin family. (378 aa) | ||||
COL4A4 | Collagen type IV alpha 4 chain. (1691 aa) | ||||
MFAP4 | Microfibril associated protein 4. (304 aa) | ||||
LOC100625180 | C-type lectin domain-containing protein. (252 aa) | ||||
PRELP | Proline and arginine rich end leucine rich repeat protein. (381 aa) | ||||
LAMB4 | Uncharacterized protein. (719 aa) | ||||
WNT2 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa) | ||||
USH2A | Uncharacterized protein. (1544 aa) | ||||
RARRES2 | Retinoic acid receptor responder 2. (177 aa) | ||||
ACAN | Aggrecan core protein 2; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage. (2434 aa) | ||||
CHADL | Chondroadherin like. (760 aa) | ||||
ADAMTS8 | ADAM metallopeptidase with thrombospondin type 1 motif 8. (1019 aa) | ||||
MMRN2 | Multimerin 2. (931 aa) | ||||
SSC5D | Scavenger receptor cysteine rich family member with 5 domains. (1634 aa) | ||||
DAG1 | Alpha-dystroglycan; The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sacrolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization. Beta-dystroglycan is a transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non- muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell ad [...] (912 aa) | ||||
COL5A2 | Collagen alpha-2(V) chain preproprotein. (1499 aa) | ||||
TNN | Tenascin N. (1472 aa) | ||||
COL28A1 | Collagen type XXVIII alpha 1 chain. (1236 aa) | ||||
FREM1 | FRAS1 related extracellular matrix 1. (2182 aa) | ||||
COL6A5 | Collagen type VI alpha 5 chain. (2337 aa) | ||||
LTBP3 | Latent transforming growth factor beta binding protein 3. (1332 aa) | ||||
NTNG1 | Netrin G1. (588 aa) | ||||
VWC2 | Von Willebrand factor C domain containing 2. (325 aa) | ||||
LOC100517188 | Uncharacterized protein. (1592 aa) | ||||
CILP | Cartilage intermediate layer protein 1 C2; Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligand-induced IGF1R autophosphorylation. May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1. Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage (By similarity). (1193 aa) | ||||
COL11A2 | Collagen type XI alpha 2 chain. (1796 aa) | ||||
TNR | Tenascin R. (1270 aa) | ||||
SMOC1 | SPARC related modular calcium binding 1. (469 aa) | ||||
THBS2 | Thrombospondin 2. (1223 aa) | ||||
EMILIN1 | Elastin microfibril interfacer 1. (1292 aa) | ||||
LAD1 | Uncharacterized protein. (582 aa) | ||||
TECTA | Tectorin alpha. (2469 aa) | ||||
A0A5G2QUL4_PIG | Uncharacterized protein. (536 aa) | ||||
AMELX | Uncharacterized protein. (203 aa) | ||||
COL9A1 | Collagen type IX alpha 1 chain. (922 aa) | ||||
DEF8 | Differentially expressed in FDCP 8 homolog. (522 aa) | ||||
ABI3BP | ABI family member 3 binding protein. (1668 aa) | ||||
COL4A1 | Collagen IV NC1 domain-containing protein. (461 aa) | ||||
PLOD3 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (744 aa) | ||||
MGP | Matrix Gla protein; Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation. (127 aa) | ||||
HTRA1 | HtrA serine peptidase 1. (479 aa) | ||||
ANGPT1 | Angiopoietin-1; Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development (By similarity). (510 aa) | ||||
COL14A1 | Collagen alpha-1(XIV) chain isoform X1. (1796 aa) | ||||
FBN2 | Fibrillin 2. (2910 aa) | ||||
ACHE | Acetylcholinesterase (Cartwright blood group); Belongs to the type-B carboxylesterase/lipase family. (765 aa) | ||||
COL9A2 | Uncharacterized protein. (709 aa) | ||||
COL6A1 | Collagen type VI alpha 1 chain. (1028 aa) | ||||
COL1A1 | Collagen type I alpha 1 chain. (1477 aa) | ||||
LOXL3 | Lysyl oxidase like 3. (814 aa) | ||||
FRAS1 | Fraser extracellular matrix complex subunit 1. (4013 aa) | ||||
ANGPT2 | Angiopoietin-2; Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating angiogenic signals mediated by ANGPT1. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell- matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal (By similarity). (495 aa) | ||||
FCN1 | Ficolin-1; Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen- associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8. Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage (By similarity). (405 aa) | ||||
ANG | Ribonuclease 4; This RNase has marked specificity towards the 3' side of uridine nucleotides; Belongs to the pancreatic ribonuclease family. (177 aa) | ||||
IMPG1 | Interphotoreceptor matrix proteoglycan 1. (787 aa) | ||||
ITGB4 | Integrin beta. (1814 aa) | ||||
A0A5G2QWB6_PIG | Uncharacterized protein. (979 aa) | ||||
LTBP4 | Latent transforming growth factor beta binding protein 4. (1622 aa) | ||||
ADAMTS1 | Peptidase M12B domain-containing protein. (963 aa) | ||||
TGFBR3 | Transforming growth factor beta receptor type 3; Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors. (952 aa) | ||||
COL6A6 | Collagen type VI alpha 6 chain. (2266 aa) | ||||
CASK | Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (925 aa) | ||||
MATN4 | Matrilin 4. (774 aa) | ||||
A0A5G2RI39_PIG | C-type lectin domain-containing protein. (217 aa) | ||||
LGALSL | Galectin. (183 aa) | ||||
AMELY | Amelogenin; Plays a role in the biomineralization of teeth. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel; Belongs to the amelogenin family. (189 aa) | ||||
COL11A1 | Collagen type XI alpha 1 chain. (1816 aa) | ||||
COL21A1 | Collagen type XXI alpha 1 chain. (957 aa) | ||||
SPARC | SPARC; Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity (By similarity); Belongs to the SPARC family. (331 aa) |