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SLC1A2 SLC1A2 STEAP4 STEAP4 PXDN PXDN P2RX3 P2RX3 COL1A2 COL1A2 CLYBL CLYBL MSR1 MSR1 SLC1A5 SLC1A5 SIGMAR1 SIGMAR1 MLKL MLKL PNPT1 PNPT1 ITLN2 ITLN2 CD74 CD74 ALOX5AP ALOX5AP SCARA5 SCARA5 MIF MIF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC1A2Amino acid transporter. (639 aa)
STEAP4Metalloreductase STEAP4. (470 aa)
PXDNPeroxidasin. (1529 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
COL1A2Fibrillar collagen NC1 domain-containing protein. (1135 aa)
CLYBLCitramalyl-CoA lyase, mitochondrial isoform X1. (341 aa)
MSR1Macrophage scavenger receptor 1. (446 aa)
SLC1A5Amino acid transporter. (541 aa)
SIGMAR1Sigma non-opioid intracellular receptor 1. (223 aa)
MLKLMixed lineage kinase domain like pseudokinase. (477 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1, mitochondrial. (784 aa)
ITLN2Intelectin 2. (388 aa)
CD74Thyroglobulin type-1 domain-containing protein. (347 aa)
ALOX5APArachidonate 5-lipoxygenase-activating protein; Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes (By similarity); Belongs to the MAPEG family. (161 aa)
SCARA5SRCR domain-containing protein. (269 aa)
MIFMacrophage migration inhibitory factor; Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity (By simi [...] (115 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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