(8 nodes) Mitochondrial tRNA modification network (Sus scrofa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TRIT1	tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family. (470 aa)
	MTO1	Mitochondrial tRNA translation optimization 1. (691 aa)
	RPUSD4	RNA pseudouridylate synthase domain-containing protein 4. (376 aa)
	TRMT10C	tRNA methyltransferase 10C, mitochondrial RNase P subunit. (415 aa)
	TRMT5	tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. (504 aa)
	SNTA1	Uncharacterized protein. (1071 aa)
	HSD17B10	Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (293 aa)
	TRMT61B	tRNA methyltransferase 61B. (492 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HSD17B10	TRMT10C	ENSSSCP00000029637	ENSSSCP00000055430	Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	tRNA methyltransferase 10C, mitochondrial RNase P subunit.	0.946
HSD17B10	TRMT61B	ENSSSCP00000029637	ENSSSCP00000022671	Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	tRNA methyltransferase 61B.	0.428
MTO1	SNTA1	ENSSSCP00000004841	ENSSSCP00000050637	Mitochondrial tRNA translation optimization 1.	Uncharacterized protein.	0.599
MTO1	TRIT1	ENSSSCP00000004841	ENSSSCP00000003971	Mitochondrial tRNA translation optimization 1.	tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family.	0.673
MTO1	TRMT10C	ENSSSCP00000004841	ENSSSCP00000055430	Mitochondrial tRNA translation optimization 1.	tRNA methyltransferase 10C, mitochondrial RNase P subunit.	0.515
MTO1	TRMT5	ENSSSCP00000004841	ENSSSCP00000055032	Mitochondrial tRNA translation optimization 1.	tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family.	0.587
MTO1	TRMT61B	ENSSSCP00000004841	ENSSSCP00000022671	Mitochondrial tRNA translation optimization 1.	tRNA methyltransferase 61B.	0.454
RPUSD4	SNTA1	ENSSSCP00000016154	ENSSSCP00000050637	RNA pseudouridylate synthase domain-containing protein 4.	Uncharacterized protein.	0.618
RPUSD4	TRIT1	ENSSSCP00000016154	ENSSSCP00000003971	RNA pseudouridylate synthase domain-containing protein 4.	tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family.	0.750
RPUSD4	TRMT10C	ENSSSCP00000016154	ENSSSCP00000055430	RNA pseudouridylate synthase domain-containing protein 4.	tRNA methyltransferase 10C, mitochondrial RNase P subunit.	0.528
RPUSD4	TRMT5	ENSSSCP00000016154	ENSSSCP00000055032	RNA pseudouridylate synthase domain-containing protein 4.	tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family.	0.590
RPUSD4	TRMT61B	ENSSSCP00000016154	ENSSSCP00000022671	RNA pseudouridylate synthase domain-containing protein 4.	tRNA methyltransferase 61B.	0.690
SNTA1	MTO1	ENSSSCP00000050637	ENSSSCP00000004841	Uncharacterized protein.	Mitochondrial tRNA translation optimization 1.	0.599
SNTA1	RPUSD4	ENSSSCP00000050637	ENSSSCP00000016154	Uncharacterized protein.	RNA pseudouridylate synthase domain-containing protein 4.	0.618
SNTA1	TRIT1	ENSSSCP00000050637	ENSSSCP00000003971	Uncharacterized protein.	tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family.	0.804
SNTA1	TRMT5	ENSSSCP00000050637	ENSSSCP00000055032	Uncharacterized protein.	tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family.	0.629
SNTA1	TRMT61B	ENSSSCP00000050637	ENSSSCP00000022671	Uncharacterized protein.	tRNA methyltransferase 61B.	0.556
TRIT1	MTO1	ENSSSCP00000003971	ENSSSCP00000004841	tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family.	Mitochondrial tRNA translation optimization 1.	0.673
TRIT1	RPUSD4	ENSSSCP00000003971	ENSSSCP00000016154	tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family.	RNA pseudouridylate synthase domain-containing protein 4.	0.750
TRIT1	SNTA1	ENSSSCP00000003971	ENSSSCP00000050637	tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family.	Uncharacterized protein.	0.804