STRINGSTRING
DDX23 DDX23 SNRPF SNRPF PRPF4B PRPF4B CDC5L CDC5L GPATCH1 GPATCH1 SNRNP40 SNRNP40 SNRPD1 SNRPD1 MAGOH MAGOH SYNCRIP SYNCRIP FRG1 FRG1 BUD31 BUD31 SNRNP200 SNRNP200 SF3B6 SF3B6 ZCCHC8 ZCCHC8 TFIP11 TFIP11 SNRPD3 SNRPD3 EIF4A2 EIF4A2 SF3B2 SF3B2 SART1 SART1 PRPF19 PRPF19 WDR83 WDR83 CWC22 CWC22 PPIL3 PPIL3 MTREX MTREX CWC27 CWC27 PPWD1 PPWD1 SLU7 SLU7 EIF4A3 EIF4A3 EFTUD2 EFTUD2 DHX8 DHX8 PRPF8 PRPF8 SNW1 SNW1 I3LBC7_PIG I3LBC7_PIG SNRPN SNRPN SNRPE SNRPE RBM8A RBM8A RBM22 RBM22 SNRPG SNRPG PABPC1 PABPC1 RBMX RBMX SF3B1 SF3B1 AQR AQR PPIE PPIE A0A286ZN96_PIG A0A286ZN96_PIG HNRNPA1 HNRNPA1 HNRNPU HNRNPU CDC40 CDC40 PNN PNN C19orf54 C19orf54 LOC102162880 LOC102162880 RBM44 RBM44 SNRPB2 SNRPB2 SF3A1 SF3A1 WDR25 WDR25 DDX41 DDX41 PPIL1 PPIL1 SNRPB SNRPB U2AF1 U2AF1 RALY RALY A0A287ANQ5_PIG A0A287ANQ5_PIG SF3B3 SF3B3 PRPF6 PRPF6 ESS2 ESS2 SRRM1 SRRM1 PPIL2 PPIL2 SYF2 SYF2 A0A287B019_PIG A0A287B019_PIG LSM2 LSM2 SRRM2 SRRM2 DHX38 DHX38 CACTIN CACTIN DDX5 DDX5 SRSF1 SRSF1 AMH AMH HNRNPR HNRNPR CWC15 CWC15 DHX35 DHX35 BTBD19 BTBD19 A0A5G2QJP9_PIG A0A5G2QJP9_PIG SNRPA1 SNRPA1 A0A5G2QMF2_PIG A0A5G2QMF2_PIG SNRPD2 SNRPD2 CRNKL1 CRNKL1 XAB2 XAB2 LSM7 LSM7 SF3A3 SF3A3 LSM3 LSM3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DDX23DEAD (Asp-Glu-Ala-Asp) box polypeptide 23. (820 aa)
SNRPFSm domain-containing protein. (86 aa)
PRPF4BPre-mRNA processing factor 4B. (1056 aa)
CDC5LCell division cycle 5-like protein. (802 aa)
GPATCH1G-patch domain containing 1. (932 aa)
SNRNP40Small nuclear ribonucleoprotein U5 subunit 40. (355 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa)
MAGOHMago homolog, exon junction complex subunit. (146 aa)
SYNCRIPSynaptotagmin binding cytoplasmic RNA interacting protein. (623 aa)
FRG1FSHD region gene 1. (257 aa)
BUD31Protein BUD31 homolog isoform X2. (144 aa)
SNRNP200U5 small nuclear ribonucleoprotein 200 kDa helicase isoform X1. (2136 aa)
SF3B6Splicing factor 3B subunit 6. (125 aa)
ZCCHC8Zinc finger CCHC-type containing 8. (767 aa)
TFIP11Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (836 aa)
SNRPD3Sm domain-containing protein. (281 aa)
EIF4A2Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family. (410 aa)
SF3B2Splicing factor 3B subunit 2 isoform X1. (895 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (803 aa)
PRPF19Pre-mRNA-processing factor 19. (504 aa)
WDR83WD repeat domain-containing protein 83. (311 aa)
CWC22CWC22 spliceosome associated protein homolog. (903 aa)
PPIL3Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (161 aa)
MTREXExosome RNA helicase MTR4. (1042 aa)
CWC27Peptidyl-prolyl cis-trans isomerase CWC27 homolog isoform 1. (472 aa)
PPWD1Peptidylprolyl isomerase domain and WD repeat-containing protein 1 isoform 1. (646 aa)
SLU7Pre-mRNA-splicing factor SLU7 isoform X1. (586 aa)
EIF4A3Eukaryotic initiation factor 4A-III, N-terminally processed; ATP-dependent RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expr [...] (488 aa)
EFTUD2116 kDa U5 small nuclear ribonucleoprotein component. (972 aa)
DHX8DEAH-box helicase 8. (1211 aa)
PRPF8Pre-mRNA processing factor 8. (2335 aa)
SNW1SNW domain-containing protein 1 isoform 2. (536 aa)
I3LBC7_PIGPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (110 aa)
SNRPNSmall nuclear ribonucleoprotein-associated protein. (250 aa)
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa)
RBM22RNA binding motif protein 22. (559 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (636 aa)
RBMXRNA binding motif protein X-linked. (408 aa)
SF3B1Splicing factor 3B subunit 1 isoform 1. (1304 aa)
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1492 aa)
PPIEPeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (310 aa)
A0A286ZN96_PIGRRM domain-containing protein. (90 aa)
HNRNPA1Heterogeneous nuclear ribonucleoprotein A1. (373 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U isoform a. (825 aa)
CDC40Pre-mRNA-processing factor 17. (579 aa)
PNNUncharacterized protein. (736 aa)
C19orf54Chromosome 19 open reading frame 54. (366 aa)
LOC102162880Uncharacterized protein. (256 aa)
RBM44RNA binding motif protein 44. (1056 aa)
SNRPB2RU2B. (225 aa)
SF3A1Splicing factor 3a subunit 1. (722 aa)
WDR25WD repeat domain 25. (536 aa)
DDX41DEAD-box helicase 41. (782 aa)
PPIL1Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (231 aa)
U2AF1Splicing factor U2AF 35 kDa subunit; Plays a critical role in both constitutive and enhancer- dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron (By similarity). (239 aa)
RALYRALY heterogeneous nuclear ribonucleoprotein. (365 aa)
A0A287ANQ5_PIGUncharacterized protein. (412 aa)
SF3B3Splicing factor 3B subunit 3. (1217 aa)
PRPF6Pre-mRNA processing factor 6. (1150 aa)
ESS2Ess-2 splicing factor homolog. (521 aa)
SRRM1Serine and arginine repetitive matrix 1. (968 aa)
PPIL2Peptidyl-prolyl cis-trans isomerase-like 2 isoform X1. (522 aa)
SYF2SYF2 pre-mRNA splicing factor. (245 aa)
A0A287B019_PIGRRM domain-containing protein. (135 aa)
LSM2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
SRRM2Serine/arginine repetitive matrix 2. (2662 aa)
DHX38DEAH-box helicase 38. (1325 aa)
CACTINCactin, spliceosome C complex subunit. (755 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (617 aa)
SRSF1Serine/arginine-rich splicing factor 1; Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site- containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5'-CGAGGCG-3' motif in vitro. Three copies of the octame [...] (253 aa)
AMHMuellerian-inhibiting factor; This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin (By similarity). (577 aa)
HNRNPRHeterogeneous nuclear ribonucleoprotein R isoform X2. (633 aa)
CWC15CWC15 spliceosome associated protein homolog. (254 aa)
DHX35Putative ATP-dependent RNA helicase DHX35 isoform 1. (732 aa)
BTBD19BTB domain containing 19. (290 aa)
A0A5G2QJP9_PIGUncharacterized protein. (1151 aa)
SNRPA1Small nuclear ribonucleoprotein polypeptide A. (269 aa)
A0A5G2QMF2_PIGRRM domain-containing protein. (318 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (140 aa)
CRNKL1Crooked neck pre-mRNA splicing factor 1. (693 aa)
XAB2XPA binding protein 2. (858 aa)
LSM7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (150 aa)
SF3A3Splicing factor 3a subunit 3. (517 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (105 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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