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SMDT1 | Single-pass membrane protein with aspartate rich tail 1. (107 aa) | ||||
KCTD17 | Potassium channel tetramerization domain containing 17. (356 aa) | ||||
KCNA1 | Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa) | ||||
MCUR1 | Mitochondrial calcium uniporter regulator 1. (437 aa) | ||||
HCRTR2 | Orexin receptor type 2; Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides. Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding. (444 aa) | ||||
PKHD1 | PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4075 aa) | ||||
PML | Promyelocytic leukemia. (827 aa) | ||||
PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (463 aa) | ||||
CALB2 | Uncharacterized protein. (348 aa) | ||||
APOE | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (292 aa) | ||||
BAX | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; Belongs to the Gfo/Idh/MocA family. (480 aa) | ||||
HRC | Sarcoplasmic reticulum histidine-rich calcium-binding protein. (620 aa) | ||||
GRIK2 | Glutamate ionotropic receptor kainate type subunit 2. (908 aa) | ||||
TRPM7 | Transient receptor potential cation channel subfamily M member 7. (1886 aa) | ||||
SLC24A5 | Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (501 aa) | ||||
SLC24A2 | Sodium/potassium/calcium exchanger 2 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (664 aa) | ||||
CALB1 | Calbindin 1. (261 aa) | ||||
TRPA1 | Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1145 aa) | ||||
SV2A | Synaptic vesicle glycoprotein 2A isoform 1. (742 aa) | ||||
CASQ2 | Calsequestrin-2; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, especially at the interface between subunits. Can bind around 60 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR2; this plays an important role in triggering muscle contraction. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats. (405 aa) | ||||
SYPL2 | Synaptophysin like 2. (278 aa) | ||||
MICU3 | Mitochondrial calcium uptake family member 3. (527 aa) | ||||
SLC24A3 | Solute carrier family 24 member 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (743 aa) | ||||
F1RNR1_PIG | G_PROTEIN_RECEP_F3_4 domain-containing protein. (379 aa) | ||||
UMOD | Uromodulin. (642 aa) | ||||
CNNM4 | Cyclin and CBS domain divalent metal cation transport mediator 4. (775 aa) | ||||
ATP6V1B1 | Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (395 aa) | ||||
FKBP1B | Peptidylprolyl isomerase. (108 aa) | ||||
LETM1 | Leucine zipper and EF-hand containing transmembrane protein 1. (791 aa) | ||||
SLC30A9 | Uncharacterized protein. (541 aa) | ||||
EDNRA | Endothelin-1 receptor; Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3 (By similarity). (427 aa) | ||||
TRPC3 | Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (921 aa) | ||||
MCUB | Calcium uniporter regulatory subunit MCUb, mitochondrial isoform X1. (335 aa) | ||||
PKD2 | Polycystin 2, transient receptor potential cation channel. (970 aa) | ||||
GPR12 | G protein-coupled receptor 12; Belongs to the G-protein coupled receptor 1 family. (334 aa) | ||||
KL | Klotho. (1011 aa) | ||||
TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (319 aa) | ||||
STC1 | Stanniocalcin 1. (247 aa) | ||||
SLC8B1 | Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (604 aa) | ||||
CDH23 | Cadherin related 23. (3354 aa) | ||||
MCU | Calcium uniporter protein, mitochondrial isoform 1. (351 aa) | ||||
PDZD8 | PDZ domain-containing protein 8. (1154 aa) | ||||
ATP2B2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1235 aa) | ||||
ATP13A4 | Uncharacterized protein. (212 aa) | ||||
DRD3 | Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (447 aa) | ||||
APP | Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (756 aa) | ||||
TCIRG1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (862 aa) | ||||
SLC39A13 | Zinc transporter SLC39A7; Zinc transporter, that transports Zn(2+) from the endoplasmic reticulum/Golgi apparatus to the cytosol; Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily. (372 aa) | ||||
F2 | Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity). (623 aa) | ||||
CSRP3 | Uncharacterized protein. (200 aa) | ||||
CRSP3 | Calcitonin receptor-stimulating peptide 3; Belongs to the calcitonin family. (125 aa) | ||||
CRSP-2 | Calcitonin receptor-stimulating peptide 2; Belongs to the calcitonin family. (117 aa) | ||||
PTH | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D- glucose (2DG) transport and glycogen synthesis in osteoblastic cells (By similarity). (115 aa) | ||||
F1SA33_PIG | G_PROTEIN_RECEP_F3_4 domain-containing protein. (349 aa) | ||||
HEXB | Beta-hexosaminidase subunit beta; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. (538 aa) | ||||
AP3B1 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1130 aa) | ||||
F1SUY7_PIG | Uncharacterized protein; Belongs to the transient receptor (TC 1.A.4) family. (888 aa) | ||||
HTR2B | 5-hydroxytryptamine receptor 2B; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide- binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity [...] (481 aa) | ||||
TRIM24 | Transcription intermediary factor 1-alpha isoform X1. (1050 aa) | ||||
CAV2 | Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity); Belongs to the caveolin family. (162 aa) | ||||
SNX10 | Sorting nexin-10 isoform 1. (200 aa) | ||||
ANKH | ANKH inorganic pyrophosphate transport regulator. (494 aa) | ||||
STC2 | Stanniocalcin-2. (301 aa) | ||||
SGCD | Sarcoglycan delta. (290 aa) | ||||
ANXA6 | Annexin. (672 aa) | ||||
FAM20A | FAM20A golgi associated secretory pathway pseudokinase. (541 aa) | ||||
LOC100739663 | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa) | ||||
RMDN2 | Regulator of microtubule dynamics 2. (569 aa) | ||||
CCDC47 | Coiled-coil domain-containing protein 47. (483 aa) | ||||
SLC35G1 | Solute carrier family 35 member G1 isoform 1. (366 aa) | ||||
CALCB | Calcitonin; Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones; Belongs to the calcitonin family. (141 aa) | ||||
MT-2B | Metallothionein-2A; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. (61 aa) | ||||
CYP27B1 | Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (500 aa) | ||||
TMEM178A | Transmembrane protein 178A. (297 aa) | ||||
MT1A | Metallothionein-1A; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. (113 aa) | ||||
GPER1 | G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (360 aa) | ||||
SLC39A6 | Solute carrier family 39 member 6. (811 aa) | ||||
GRM5 | Glutamate metabotropic receptor 5. (1212 aa) | ||||
ATP13A5 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1219 aa) | ||||
SLC39A14 | Solute carrier family 39 member 14. (531 aa) | ||||
SLC39A4 | Solute carrier family 39 member 4. (816 aa) | ||||
ATP2B3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1193 aa) | ||||
KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1360 aa) | ||||
BCAP31 | B-cell receptor-associated protein 31 isoform b. (246 aa) | ||||
TGFB1 | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa) | ||||
NT5E | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (574 aa) | ||||
HTR2C | 5-hydroxytryptamine receptor 2C. (457 aa) | ||||
CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (177 aa) | ||||
SLC8A2 | Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (1002 aa) | ||||
DHRS7C | Dehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (308 aa) | ||||
MICU1 | Mitochondrial calcium uptake 1. (509 aa) | ||||
SLC30A7 | Solute carrier family 30 member 7. (376 aa) | ||||
BAK1 | Uncharacterized protein. (266 aa) | ||||
STIM2 | Stromal interaction molecule 2. (483 aa) | ||||
CAV3 | Caveolin-3; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress. Mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae. (151 aa) | ||||
SLC30A4 | Solute carrier family 30 member 4. (429 aa) | ||||
CCL8 | C-C motif chemokine 8; Chemotactic factor that attracts monocytes. This protein can bind heparin. (99 aa) | ||||
MT1D | Metallothionein-1C; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. (61 aa) | ||||
HTR2A | 5-hydroxytryptamine receptor 2A; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5- dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. S [...] (470 aa) | ||||
MT3 | Metallothionein-3; Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro (By similarity); Belongs to the metallothionein superfamily. Type 1 family. (95 aa) | ||||
PACS2 | Phosphofurin acidic cluster sorting protein 2 isoform X1. (889 aa) | ||||
ATP2A3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1020 aa) | ||||
GRIA1 | Glutamate ionotropic receptor AMPA type subunit 1. (906 aa) | ||||
STOML2 | Stomatin like 2. (356 aa) | ||||
C19orf12 | Chromosome 19 open reading frame 12. (108 aa) | ||||
SLC25A23 | Solute carrier family 25 member 23; Belongs to the mitochondrial carrier (TC 2.A.29) family. (524 aa) | ||||
PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) | ||||
MAIP1 | Matrix AAA peptidase interacting protein 1. (288 aa) | ||||
ATP13A3 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1312 aa) | ||||
TMTC4 | Transmembrane O-mannosyltransferase targeting cadherins 4. (762 aa) | ||||
HCRTR1 | Orexin receptor type 1; Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding. (425 aa) | ||||
ATP2A2 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Isoform SERCA2A is involved in the regulation of the contraction/relaxation cycle. Acts as a regulator of TNFSF11-mediated Ca(2+) signaling pathways via its interaction with TMEM64 which is critical for the TNFSF11-induced CREB1 activation and mitochondrial ROS generation necessary for proper osteoclast generation. Association between TMEM64 and SERCA2 in the ER leads to cytos [...] (1042 aa) | ||||
WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) | ||||
EDN2 | Endothelin 2. (180 aa) | ||||
ATP2B1 | Plasma membrane calcium-transporting ATPase 1; Catalyzes the hydrolysis of ATP coupled with the transport of calcium from the cytoplasm to the extracellular space thereby maintaining intracellular calcium homeostasis. Plays a role in blood pressure regulation through regulation of intracellular calcium concentration and nitric oxide production leading to regulation of vascular smooth muscle cells vasoconstriction. Positively regulates bone mineralization through absorption of calcium from the intestine. Plays dual roles in osteoclast differentiation and survival by regulating RANKL-ind [...] (1249 aa) | ||||
SLC39A8 | Solute carrier family 39 member 8. (461 aa) | ||||
TMEM203 | Transmembrane protein 203. (136 aa) | ||||
TFAP2B | Transcription factor AP-2 beta. (469 aa) | ||||
DMPK | DM1 protein kinase. (590 aa) | ||||
NPTN | Neuroplastin. (412 aa) | ||||
CALCB-2 | Calcitonin receptor-stimulating peptide 1; Stimulates cAMP production in porcine kidney cell line LLC- PK1 via the calcitonin receptor (CT) but not via the CT-like (CL) receptor. (259 aa) | ||||
CASR | Extracellular calcium-sensing receptor; G-protein-coupled receptor that senses changes in the extracellular concentration of calcium ions and plays a key role in maintaining calcium homeostasis. Senses fluctuations in the circulating calcium concentration and modulates the production of parathyroid hormone (PTH) in parathyroid glands (By similarity). The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. The G-protein- coupled receptor activity is activated by a co-agonist mechanism: aromatic amino acids, such as [...] (1089 aa) | ||||
GCM2 | Glial cells missing transcription factor 2. (503 aa) | ||||
CHERP | Calcium homeostasis endoplasmic reticulum protein. (916 aa) | ||||
FIS1 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa) | ||||
SLC11A1 | Natural resistance-associated macrophage protein 1; Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis [...] (538 aa) | ||||
A0A287AEK4_PIG | Uncharacterized protein. (85 aa) | ||||
SLC39A12 | Solute carrier family 39 member 12. (728 aa) | ||||
SLC30A10 | Uncharacterized protein. (260 aa) | ||||
ATP1B1 | Sodium/potassium-transporting ATPase subunit beta-1; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. (325 aa) | ||||
EDN1 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides. Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (203 aa) | ||||
LCK | Tyrosine-protein kinase. (520 aa) | ||||
ATP13A2 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1131 aa) | ||||
SLC39A5 | Solute carrier family 39 member 5. (554 aa) | ||||
SLC30A8 | Solute carrier family 30 member 8. (369 aa) | ||||
SLC24A1 | Solute carrier family 24 member 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (1088 aa) | ||||
BOK | BCL2 family apoptosis regulator BOK. (288 aa) | ||||
ATP2A1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1021 aa) | ||||
GRINA | Glutamate ionotropic receptor NMDA type subunit associated protein 1. (356 aa) | ||||
SLC30A5 | Uncharacterized protein. (793 aa) | ||||
CNNM2 | Cyclin and CBS domain divalent metal cation transport mediator 2. (875 aa) | ||||
ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1171 aa) | ||||
SELENOK | Selenoprotein K; Required for Ca(2+) flux in immune cells and plays a role in T-cell proliferation and in T-cell and neutrophil migration (By similarity). Involved in endoplasmic reticulum-associated degradation (ERAD) of soluble glycosylated proteins (By similarity). Required for palmitoylation and cell surface expression of CD36 and involved in macrophage uptake of low-density lipoprotein and in foam cell formation (By similarity). Together with ZDHHC6, required for palmitoylation of ITPR1 in immune cells, leading to regulate ITPR1 stability and function. Plays a role in protection o [...] (93 aa) | ||||
SLC39A10 | Solute carrier family 39 member 10. (837 aa) | ||||
TMC8 | Transmembrane channel-like protein. (699 aa) | ||||
TMEM64 | Transmembrane protein 64. (387 aa) | ||||
CDH5 | Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity). This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (By similarity). It associates with alpha-catenin forming a link to the cytoskeleton (By similarity). Acts in concert with KRIT1 and MPP5 to establish and maintain correct endotheli [...] (782 aa) | ||||
FATE1 | Fetal and adult testis-expressed transcript protein homolog; Involved in the regulation of endoplasmic reticulum (ER)- mitochondria coupling. Negatively regulates the ER-mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling. (171 aa) | ||||
GRM1 | Glutamate metabotropic receptor 1. (1195 aa) | ||||
ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa) | ||||
TRPV5 | Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family. (792 aa) | ||||
FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (243 aa) | ||||
CIB3 | Calcium and integrin binding family member 3. (206 aa) | ||||
MYH7B | Myosin heavy chain 7B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1748 aa) | ||||
MICU2 | Calcium uptake protein 2, mitochondrial isoform X1. (430 aa) | ||||
CLN3 | Battenin. (414 aa) | ||||
CD40 | Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity). (278 aa) | ||||
TMCO1 | Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling, thereby playing a key role in calcium homeostasis. In response to endoplasmic reticulum overloading, assembles into a homotetramer, forming a functional calcium-selective channel, regulating the calcium content in endoplasmic reticulum store. Belongs to the TMCO1 family. (246 aa) | ||||
RMDN3 | Regulator of microtubule dynamics 3. (470 aa) | ||||
STIM1 | Stromal interaction molecule 1. (791 aa) | ||||
WFS1 | Wolframin ER transmembrane glycoprotein. (889 aa) | ||||
MT4 | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (62 aa) | ||||
VDR | Vitamin D3 receptor; Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells (By similarity). Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR (By similarity). The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes (By similarity). Plays a central role in calcium homeostasis (By similarity). (520 aa) | ||||
HERPUD1 | Homocysteine inducible ER protein with ubiquitin like domain 1. (389 aa) | ||||
ATF4 | Activating transcription factor 4. (329 aa) | ||||
SLC30A1 | Solute carrier family 30 member 1. (506 aa) | ||||
SLC8A1 | Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (972 aa) | ||||
TRPC1 | Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (794 aa) | ||||
CNNM3 | Cyclin and CBS domain divalent metal cation transport mediator 3. (863 aa) | ||||
SLC37A4 | Solute carrier family 37 member 4. (451 aa) | ||||
ALPL | Alkaline phosphatase. (834 aa) | ||||
ATP13A1 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1252 aa) | ||||
VAPB | Vesicle-associated membrane protein-associated protein B; Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation. (309 aa) | ||||
A0A5G2QS04_PIG | XRCC1_N domain-containing protein. (137 aa) | ||||
SLC41A1 | Solute carrier family 41 member 1 isoform X1. (514 aa) | ||||
SLC24A4 | Solute carrier family 24 member 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (637 aa) | ||||
SCGN | Secretagogin. (278 aa) | ||||
SLC39A7 | Zinc transporter SLC39A7. (472 aa) | ||||
IMMT | MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (753 aa) | ||||
TRPV4 | Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (924 aa) | ||||
TNNI3 | Troponin I3, cardiac type. (273 aa) | ||||
ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2759 aa) | ||||
TGM2 | Transglutaminase 2. (696 aa) | ||||
TRPC4 | Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (982 aa) | ||||
TMTC2 | Transmembrane O-mannosyltransferase targeting cadherins 2. (827 aa) | ||||
A0A5G2QXZ6_PIG | Protein kinase domain-containing protein. (408 aa) | ||||
TRPC7 | Uncharacterized protein; Belongs to the transient receptor (TC 1.A.4) family. (862 aa) | ||||
EDN3 | Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides. Belongs to the endothelin/sarafotoxin family. (231 aa) | ||||
ATP2C2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (947 aa) | ||||
SLC10A7 | Sodium/bile acid cotransporter; Does not show transport activity towards bile acids or steroid sulfates; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. (359 aa) | ||||
A0A5G2QUX5_PIG | Uncharacterized protein. (201 aa) | ||||
CHRNA7 | Uncharacterized protein. (585 aa) | ||||
TPCN2 | Uncharacterized protein. (765 aa) | ||||
KEL | Kell metallo-endopeptidase (Kell blood group). (763 aa) | ||||
BBC3 | Uncharacterized protein. (361 aa) | ||||
RYR2 | Ryanodine receptor 2. (4966 aa) | ||||
CNNM1 | Cyclin and CBS domain divalent metal cation transport mediator 1. (973 aa) | ||||
ATP2C1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (949 aa) | ||||
PTH1R | Parathyroid hormone/parathyroid hormone-related peptide receptor; Receptor for parathyroid hormone and for parathyroid hormone- related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 2 family. (641 aa) | ||||
SELENON | Selenoprotein N. (556 aa) | ||||
TMEM165 | GDT1 family protein. (350 aa) | ||||
TRPC6 | Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (939 aa) |