STRINGSTRING
PDGFB PDGFB PPARA PPARA PPARD PPARD SRF SRF BMP4 BMP4 RELA RELA SOX9 SOX9 NFATC3 NFATC3 YY1 YY1 NFIB NFIB RARA RARA ZNF512B ZNF512B ZNF512 ZNF512 NFATC4 NFATC4 REST REST HDAC4 HDAC4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDGFBPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (240 aa)
PPARAUncharacterized protein. (469 aa)
PPARDPeroxisome proliferator-activated receptor delta. (441 aa)
SRFSerum response factor. (512 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
RELATranscription factor p65 isoform 1. (573 aa)
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (511 aa)
NFATC3Nuclear factor of activated T cells 3. (1149 aa)
YY1YY1 transcription factor. (438 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
RARARetinoic acid receptor alpha isoform X1. (462 aa)
ZNF512BZinc finger protein 512B. (975 aa)
ZNF512Zinc finger protein 512. (612 aa)
NFATC4Nuclear factor of activated T cells 4. (937 aa)
RESTRE1 silencing transcription factor. (1108 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1160 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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