STRINGSTRING
PDPN PDPN DDR2 DDR2 RB1 RB1 MELTF MELTF SOX9 SOX9 IL6 IL6 FSCN1 FSCN1 PHLDB2 PHLDB2 TNXB TNXB BMP2 BMP2 COLGALT1 COLGALT1 COLGALT2 COLGALT2 EMILIN1 EMILIN1 PHLDB1 PHLDB1 SMAD3 SMAD3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDPNUncharacterized protein. (159 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (866 aa)
RB1RB transcriptional corepressor 1. (938 aa)
MELTFMelanotransferrin; Belongs to the transferrin family. (737 aa)
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (511 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (241 aa)
FSCN1Fascin. (465 aa)
PHLDB2Pleckstrin homology like domain family B member 2. (1253 aa)
TNXBUncharacterized protein. (4137 aa)
BMP2Bone morphogenetic protein 2 preproprotein. (395 aa)
COLGALT1Glycosyltransferase 25 domain containing 1. (623 aa)
COLGALT2Procollagen galactosyltransferase 2 isoform 1precursor. (626 aa)
EMILIN1Elastin microfibril interfacer 1. (1292 aa)
PHLDB1Pleckstrin homology like domain family B member 1. (1616 aa)
SMAD3Mothers against decapentaplegic homolog. (434 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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