STRINGSTRING
MTDH MTDH UTP4 UTP4 RRP12 RRP12 MRI1 MRI1 DEK DEK ADARB2 ADARB2 RSL1D1 RSL1D1 NSUN2 NSUN2 JMJD6 JMJD6 TRMT10A TRMT10A RPL11 RPL11 APEX1 APEX1 IP6K2 IP6K2 ARHGAP32 ARHGAP32 UBTF UBTF URB2 URB2 RGS22 RGS22 VWC2 VWC2 NHP2 NHP2 ADARB1 ADARB1 DDX5 DDX5 NANOG NANOG A0A287BHT2_PIG A0A287BHT2_PIG SPIN2B SPIN2B VDR VDR A0A287BGM8_PIG A0A287BGM8_PIG MDM2 MDM2 LIN28B LIN28B RPL3 RPL3 NOP10 NOP10 SUV39H1 SUV39H1 SURF6 SURF6 A0A287B3W3_PIG A0A287B3W3_PIG TP53 TP53 METTL18 METTL18 ZCCHC17 ZCCHC17 LOC100518170 LOC100518170 A0A287B166_PIG A0A287B166_PIG LOC100521485 LOC100521485 A0A287B0N5_PIG A0A287B0N5_PIG ZNRF2 ZNRF2 FHIT FHIT SPATA2 SPATA2 A0A287AVL5_PIG A0A287AVL5_PIG SF3B3 SF3B3 WDR74 WDR74 A0A287ARH8_PIG A0A287ARH8_PIG SENP3 SENP3 NUDT16 NUDT16 USP36 USP36 EWSR1 EWSR1 POP7 POP7 RRP1 RRP1 DDX55 DDX55 RAD52 RAD52 GNL2 GNL2 YPEL1 YPEL1 A0A287AJR4_PIG A0A287AJR4_PIG YPEL2 YPEL2 RBM4B RBM4B SPTY2D1 SPTY2D1 TAF1A TAF1A UTP6 UTP6 CLEC3B CLEC3B A0A287AD77_PIG A0A287AD77_PIG A0A287ACW2_PIG A0A287ACW2_PIG ANKRD24 ANKRD24 RPS7 RPS7 NUFIP1 NUFIP1 DIMT1 DIMT1 SNU13 SNU13 PWP1 PWP1 RERG RERG NOP2 NOP2 UTP20 UTP20 F1RW79_PIG F1RW79_PIG RRP36 RRP36 IMP3 IMP3 DDX24 DDX24 TAF1C TAF1C GGN GGN PNMA8A PNMA8A GRWD1 GRWD1 LIN28A LIN28A MDN1 MDN1 PAK6 PAK6 MPHOSPH10 MPHOSPH10 RCL1 RCL1 PUM3 PUM3 POP1 POP1 SF3B4 SF3B4 WDR3 WDR3 DNTTIP2 DNTTIP2 NOP56 NOP56 STK35 STK35 NSUN5 NSUN5 SBDS SBDS NOL8 NOL8 TAF1B TAF1B LYAR LYAR PPID PPID TMA16 TMA16 SDAD1 SDAD1 RRH RRH RBM19 RBM19 SRSF9 SRSF9 PES1 PES1 HEATR1 HEATR1 SIRT1 SIRT1 DDX50 DDX50 DDX21 DDX21 ERCC6 ERCC6 NPM3 NPM3 NOLC1 NOLC1 DCLRE1A DCLRE1A NOL6 NOL6 TOP2B TOP2B GNL3 GNL3 SENP5 SENP5 PHF8 PHF8 RPS6KA6 RPS6KA6 DKC1 DKC1 TUT1 TUT1 RPS13 RPS13 ELOF1 ELOF1 ZNF346 ZNF346 UTP15 UTP15 WDR55 WDR55 UBTFL1 UBTFL1 LOC100514912 LOC100514912 ZPR1 ZPR1 RPS25 RPS25 GTPBP10 GTPBP10 CDCA7L CDCA7L UTP25 UTP25 IMP4 IMP4 WDR17 WDR17 CDKN2AIP CDKN2AIP WRN WRN WDR75 WDR75 WDR12 WDR12 NCL NCL MDFIC MDFIC RAI14 RAI14 RPL26L1 RPL26L1 FBLL1 FBLL1 NOL11 NOL11 FTSJ3 FTSJ3 MAP3K14 MAP3K14 TOP2A TOP2A MED1 MED1 UTP18 UTP18 AATF AATF RRP1B RRP1B FBL FBL EBNA1BP2 EBNA1BP2 DDX18 DDX18 RPL26 RPL26 STAT4 STAT4 RSL24D1 RSL24D1 NOL9 NOL9 NOP58 NOP58 RPP21 RPP21 MKI67 MKI67 WDR43 WDR43 HUNK HUNK TOP1 TOP1 DDX27 DDX27 SMUG1 SMUG1 C15orf40 C15orf40 HIRIP3 HIRIP3 SGF29 SGF29 BMS1 BMS1 RRP9 RRP9 NPM1 NPM1 ZCCHC4 ZCCHC4 NOP53 NOP53 GAR1 GAR1 APEX2 APEX2 GNL3L GNL3L ARFGEF1 ARFGEF1 TAF1D TAF1D LOC100620900 LOC100620900 A0A286ZLE8_PIG A0A286ZLE8_PIG RBIS RBIS SPIN1 SPIN1 A0A286ZN03_PIG A0A286ZN03_PIG STAT1 STAT1 EEF1A2 EEF1A2 NOL10 NOL10 XRN2 XRN2 ARL4C ARL4C WDR36 WDR36 EXOSC9 EXOSC9 POLI POLI EEF1A1 EEF1A1 ETV6 ETV6 URB1 URB1 PA2G4 PA2G4 LOC100623257 LOC100623257 MRPL23 MRPL23 MYBBP1A MYBBP1A YPEL4 YPEL4 A0A286ZZN5_PIG A0A286ZZN5_PIG REXO5 REXO5 TCIM TCIM SIRT7 SIRT7 RIOX1 RIOX1 SPIN3 SPIN3 MEAF6 MEAF6 HDHD3 HDHD3 NSUN7 NSUN7 DDX47 DDX47 MYC MYC A0A480SS62_PIG A0A480SS62_PIG NOL12 NOL12 PARN PARN CAPN3 CAPN3 RPP38 RPP38 KDM5D KDM5D ILF2 ILF2 NMD3 NMD3 POP5 POP5 DDX56 DDX56 RPF2 RPF2 POLR2H POLR2H RPAIN RPAIN S100A16 S100A16 SELENBP1 SELENBP1 CHCHD1 CHCHD1 APTX APTX RPL5 RPL5 TCOF1 TCOF1 ARL4A ARL4A A0A5G2QWJ3_PIG A0A5G2QWJ3_PIG KAT5 KAT5 PRKRIP1 PRKRIP1 A0A5G2QSZ8_PIG A0A5G2QSZ8_PIG RBM28 RBM28 RPP30 RPP30 PWP2 PWP2 YPEL3 YPEL3 RRP7A RRP7A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MTDHMetadherin. (613 aa)
UTP4U3 small nucleolar RNA-associated protein 4 homolog isoform 1. (686 aa)
RRP12Ribosomal RNA processing 12 homolog. (1256 aa)
MRI1Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (422 aa)
DEKDEK proto-oncogene. (383 aa)
ADARB2Adenosine deaminase RNA specific B2 (inactive). (734 aa)
RSL1D1Ribosomal L1 domain-containing protein 1. (493 aa)
NSUN2NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (992 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (413 aa)
TRMT10AtRNA methyltransferase 10A. (401 aa)
RPL1160S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] (192 aa)
APEX1DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (318 aa)
IP6K2Kinase; Belongs to the inositol phosphokinase (IPK) family. (425 aa)
ARHGAP32Rho GTPase activating protein 32. (2089 aa)
UBTFUpstream binding transcription factor. (751 aa)
URB2URB2 ribosome biogenesis homolog. (1503 aa)
RGS22Regulator of G protein signaling 22. (1767 aa)
VWC2Von Willebrand factor C domain containing 2. (325 aa)
NHP2Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (178 aa)
ADARB1Adenosine deaminase RNA specific B1. (702 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (617 aa)
NANOGHomeobox domain-containing protein. (304 aa)
A0A287BHT2_PIGUncharacterized protein. (64 aa)
SPIN2BUncharacterized protein. (258 aa)
VDRVitamin D3 receptor; Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells (By similarity). Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR (By similarity). The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes (By similarity). Plays a central role in calcium homeostasis (By similarity). (520 aa)
A0A287BGM8_PIGUbiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (494 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (496 aa)
LIN28BLin-28 homolog B. (258 aa)
RPL360S ribosomal protein L3; The L3 protein is a component of the large subunit of cytoplasmic ribosomes. (403 aa)
NOP10NOP10 ribonucleoprotein. (64 aa)
SUV39H1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (462 aa)
SURF6Surfeit 6. (321 aa)
A0A287B3W3_PIGTr-type G domain-containing protein. (75 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (442 aa)
METTL18Methyltransferase like 18. (373 aa)
ZCCHC17Zinc finger CCHC-type containing 17. (241 aa)
LOC100518170Protein FAM127. (113 aa)
A0A287B166_PIGUncharacterized protein. (57 aa)
LOC100521485DUF4939 domain-containing protein. (113 aa)
A0A287B0N5_PIGRibonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (123 aa)
ZNRF2Zinc and ring finger 2. (240 aa)
FHITFragile histidine triad diadenosine triphosphatase. (150 aa)
SPATA2Spermatogenesis-associated protein 2. (520 aa)
A0A287AVL5_PIGGTP_EFTU_D3 domain-containing protein. (288 aa)
SF3B3Splicing factor 3B subunit 3. (1217 aa)
WDR74Uncharacterized protein. (388 aa)
A0A287ARH8_PIGRibosomal_S13_N domain-containing protein. (73 aa)
SENP3Sentrin-specific protease 3. (574 aa)
NUDT16Nudix hydrolase 16. (211 aa)
USP36Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (548 aa)
EWSR1EWS RNA binding protein 1. (737 aa)
POP7Ribonuclease P protein subunit p20; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences; Belongs to the histone-like Alba family. (140 aa)
RRP1Ribosomal RNA processing protein 1 homolog A. (447 aa)
DDX55RNA helicase. (600 aa)
RAD52RAD52 homolog, DNA repair protein. (406 aa)
GNL2Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (730 aa)
YPEL1Protein yippee-like; Belongs to the yippee family. (119 aa)
A0A287AJR4_PIGRibonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
YPEL2Protein yippee-like; Belongs to the yippee family. (119 aa)
RBM4BRNA-binding protein 4B; Required for the translational activation of PER1 mRNA in response to circadian clock. Binds directly to the 3'-UTR of the PER1 mRNA (By similarity). (369 aa)
SPTY2D1Uncharacterized protein. (652 aa)
TAF1ATATA box-binding protein-associated factor RNA polymerase I subunit A isoform 1. (477 aa)
UTP6UTP6 small subunit processome component. (598 aa)
CLEC3BC-type lectin domain family 3 member B. (202 aa)
A0A287AD77_PIGUncharacterized protein. (193 aa)
A0A287ACW2_PIGPeptidase_M24 domain-containing protein. (291 aa)
ANKRD24Ankyrin repeat domain 24. (1104 aa)
RPS740S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
NUFIP1Nuclear fragile X mental retardation-interacting protein 1. (494 aa)
DIMT1rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (313 aa)
SNU13Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (132 aa)
PWP1PWP1 homolog, endonuclein. (499 aa)
RERGRAS like estrogen regulated growth inhibitor. (180 aa)
NOP2SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (822 aa)
UTP20UTP20 small subunit processome component. (2781 aa)
F1RW79_PIGUncharacterized protein. (708 aa)
RRP36Novel protein similar to vertebrate chromosome 6 open reading frame 153 (C6orf153). (246 aa)
IMP3S4 RNA-binding domain-containing protein. (184 aa)
DDX24DEAD-box helicase 24. (819 aa)
TAF1CTATA-box binding protein associated factor, RNA polymerase I subunit C. (908 aa)
GGNGametogenetin. (671 aa)
PNMA8AUncharacterized protein. (174 aa)
GRWD1Glutamate rich WD repeat containing 1. (445 aa)
LIN28AProtein lin-28 homolog A. (205 aa)
MDN1Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5596 aa)
PAK6Non-specific serine/threonine protein kinase. (709 aa)
MPHOSPH10U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family. (680 aa)
RCL1RNA terminal phosphate cyclase like 1. (450 aa)
PUM3Pumilio RNA binding family member 3. (648 aa)
POP1POP1 homolog, ribonuclease P/MRP subunit. (1003 aa)
SF3B4Splicing factor 3b subunit 4. (424 aa)
WDR3WD repeat domain 3. (943 aa)
DNTTIP2Fcf2 domain-containing protein. (771 aa)
NOP56NOP56 ribonucleoprotein. (596 aa)
STK35Serine/threonine-protein kinase 35. (539 aa)
NSUN5NOP2/Sun RNA methyltransferase 5; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (466 aa)
SBDSRibosome maturation protein SBDS. (250 aa)
NOL8Nucleolar protein 8. (1123 aa)
TAF1BTATA box-binding protein-associated factor RNA polymerase I subunit B isoform a. (589 aa)
LYARLy1 antibody reactive. (386 aa)
PPIDPeptidylprolyl isomerase D. (370 aa)
TMA16Translation machinery associated 16 homolog. (205 aa)
SDAD1Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (687 aa)
RRHRetinal pigment epithelium-derived rhodopsin homolog; Belongs to the G-protein coupled receptor 1 family. (336 aa)
RBM19RNA binding motif protein 19. (940 aa)
SRSF9Uncharacterized protein. (221 aa)
PES1Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. (597 aa)
HEATR1HEAT repeat containing 1. (2141 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform a. (742 aa)
DDX50DExD-box helicase 50. (737 aa)
DDX21DEAD (Asp-Glu-Ala-Asp) box helicase 21. (784 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1462 aa)
NPM3Nucleophosmin/nucleoplasmin 3. (176 aa)
NOLC1Nucleolar and coiled-body phosphoprotein 1. (696 aa)
DCLRE1ADNA cross-link repair 1A protein isoform X1. (1058 aa)
NOL6Nucleolar protein 6. (1145 aa)
TOP2BDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1614 aa)
GNL3G protein nucleolar 3. (551 aa)
SENP5SUMO specific peptidase 5. (752 aa)
PHF8PHD finger protein 8. (1060 aa)
RPS6KA6Ribosomal protein S6 kinase. (745 aa)
DKC1Uncharacterized protein. (521 aa)
TUT1RRM domain-containing protein. (871 aa)
RPS1340S ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family. (213 aa)
ELOF1Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (180 aa)
ZNF346Zinc finger protein 346 isoform X4. (310 aa)
UTP15Uncharacterized protein. (518 aa)
WDR55WD repeat-containing protein 55; Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis. Belongs to the WD repeat WDR55 family. (384 aa)
UBTFL1Uncharacterized protein. (404 aa)
LOC100514912Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (461 aa)
ZPR1ZPR1 zinc finger. (455 aa)
RPS2540S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (125 aa)
GTPBP10GTP binding protein 10. (379 aa)
CDCA7LCell division cycle-associated 7-like protein isoform X1. (455 aa)
UTP25UTP25 small subunit processor component. (760 aa)
IMP4U3 small nucleolar ribonucleoprotein IMP4 isoform a. (291 aa)
WDR17WD repeat domain 17. (1322 aa)
CDKN2AIPCDKN2A-interacting protein isoform X1. (583 aa)
WRNWRN RecQ like helicase. (1466 aa)
WDR75WD repeat-containing protein 75 isoform 1. (831 aa)
WDR12Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (423 aa)
NCLZinc finger protein Pegasus. (724 aa)
MDFICMyoD family inhibitor domain containing. (242 aa)
RAI14ANK_REP_REGION domain-containing protein. (978 aa)
RPL26L160S ribosomal protein L26-like 1 isoform X1. (145 aa)
FBLL1rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1. (332 aa)
NOL11Nucleolar protein 11. (880 aa)
FTSJ3pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (836 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (930 aa)
TOP2ADNA topoisomerase 2-alpha; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation. (1531 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1517 aa)
UTP18U3 small nucleolar RNA-associated protein 18 homolog. (572 aa)
AATFApoptosis antagonizing transcription factor. (569 aa)
RRP1BRibosomal RNA processing 1B. (739 aa)
FBLFibrillarin. (321 aa)
EBNA1BP2EBNA1 binding protein 2. (400 aa)
DDX18RNA helicase. (786 aa)
RPL26Ribosomal protein L26. (145 aa)
STAT4Signal transducer and activator of transcription. (748 aa)
RSL24D1Ribosomal L24 domain containing 1. (163 aa)
NOL9Polynucleotide 5'-hydroxyl-kinase NOL9. (694 aa)
NOP58NOP58 ribonucleoprotein. (546 aa)
RPP21Ribonuclease P/MRP subunit p21. (162 aa)
MKI67Uncharacterized protein. (3209 aa)
WDR43WD repeat-containing protein 43. (681 aa)
HUNKHormonally up-regulated Neu-associated kinase. (714 aa)
TOP1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (769 aa)
DDX27DEAD-box helicase 27; Belongs to the DEAD box helicase family. (763 aa)
SMUG1Single-strand-selective monofunctional uracil-DNA glycosylase 1. (272 aa)
C15orf40Chromosome 15 open reading frame 40. (154 aa)
HIRIP3Uncharacterized protein. (276 aa)
SGF29SAGA complex associated factor 29. (328 aa)
BMS1BMS1 ribosome biogenesis factor. (1284 aa)
RRP9Ribosomal RNA processing 9, U3 small nucleolar RNA binding protein. (475 aa)
NPM1Nucleophosmin isoform 1. (294 aa)
ZCCHC4Zinc finger CCHC domain-containing protein 4 isoform 1. (513 aa)
NOP53Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (470 aa)
GAR1H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (210 aa)
APEX2DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (515 aa)
GNL3LG protein nucleolar 3 like. (687 aa)
ARFGEF1ADP ribosylation factor guanine nucleotide exchange factor 1. (1849 aa)
TAF1DTATA-box binding protein associated factor, RNA polymerase I subunit D. (287 aa)
LOC100620900Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (454 aa)
A0A286ZLE8_PIGRibosomal_L7Ae domain-containing protein. (74 aa)
RBISRibosomal biogenesis factor. (121 aa)
SPIN1Uncharacterized protein. (272 aa)
A0A286ZN03_PIGRibosomal_L5 domain-containing protein. (174 aa)
STAT1Signal transducer and activator of transcription 1; Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to [...] (856 aa)
EEF1A2Eukaryotic translation elongation factor 1 alpha 2. (588 aa)
NOL10Nucleolar protein 10 isoform 1. (688 aa)
XRN25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (930 aa)
ARL4CUncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (192 aa)
WDR36WD repeat domain 36. (895 aa)
EXOSC9Exosome component 9. (455 aa)
POLIDNA polymerase iota isoform a (Long). (750 aa)
EEF1A1Eukaryotic translation elongation factor 1 alpha 1. (502 aa)
ETV6Transcription factor ETV6. (452 aa)
URB1URB1 ribosome biogenesis homolog. (2255 aa)
PA2G4Proliferation-associated 2G4. (372 aa)
LOC100623257Upstream-binding factor 1-like protein 1. (402 aa)
MRPL23Uncharacterized protein. (261 aa)
MYBBP1AMYB binding protein 1a. (1594 aa)
YPEL4Yippee like 4. (186 aa)
A0A286ZZN5_PIGTr-type G domain-containing protein. (74 aa)
REXO5RNA exonuclease 5. (787 aa)
TCIMTranscriptional and immune response regulator. (106 aa)
SIRT7Sirtuin 7. (447 aa)
RIOX1Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (667 aa)
SPIN3Spindlin family member 3. (358 aa)
MEAF6MYST/Esa1 associated factor 6. (216 aa)
HDHD3Haloacid dehalogenase like hydrolase domain containing 3. (251 aa)
NSUN7NOP2/Sun RNA methyltransferase family member 7; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (724 aa)
DDX47Putative ATP-dependent RNA helicase DDX47; Belongs to the DEAD box helicase family. (493 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (452 aa)
A0A480SS62_PIGSpindlin-1. (248 aa)
NOL12Uncharacterized protein. (309 aa)
PARNPoly(A)-specific ribonuclease. (715 aa)
CAPN3Calpain-3; Calcium-regulated non-lysosomal thiol-protease; Belongs to the peptidase C2 family. (830 aa)
RPP38Ribonuclease P/MRP subunit p38. (285 aa)
KDM5DLysine demethylase 5D. (1506 aa)
ILF2Interleukin enhancer binding factor 2. (395 aa)
NMD360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (525 aa)
POP5POP5 homolog, ribonuclease P/MRP subunit. (242 aa)
DDX56Uncharacterized protein. (554 aa)
RPF2Ribosome production factor 2 homolog. (306 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (153 aa)
RPAINRPA interacting protein. (230 aa)
S100A16Protein S100; Belongs to the S-100 family. (103 aa)
SELENBP1Selenium binding protein 1. (513 aa)
CHCHD1Coiled-coil-helix-coiled-coil-helix domain containing 1. (125 aa)
APTXAprataxin; DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP- NH(2)) and diadenosine tetraphosphate (AppppA), b [...] (356 aa)
RPL560S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] (299 aa)
TCOF1Treacle ribosome biogenesis factor 1. (1399 aa)
ARL4AADP-ribosylation factor-like protein 4A. (200 aa)
A0A5G2QWJ3_PIGUncharacterized protein. (267 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (576 aa)
PRKRIP1PRKR interacting protein 1. (238 aa)
A0A5G2QSZ8_PIG40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (91 aa)
RBM28RNA binding motif protein 28. (758 aa)
RPP30Ribonuclease P protein subunit p30. (268 aa)
PWP2Uncharacterized protein. (1096 aa)
YPEL3Protein yippee-like; Belongs to the yippee family. (157 aa)
RRP7ARibosomal RNA processing 7 homolog A. (412 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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