STRINGSTRING
SYNPO SYNPO TPM3 TPM3 CD2AP CD2AP MYO10 MYO10 DCTN2 DCTN2 CDC42EP3 CDC42EP3 MYO1E MYO1E MYL9 MYL9 MYO5B MYO5B MYLPF MYLPF AFAP1L1 AFAP1L1 HCLS1 HCLS1 MYO1F MYO1F MYH7 MYH7 DYNLL2 DYNLL2 SNX9 SNX9 TNNT1 TNNT1 CTTN CTTN MYADM MYADM MYO6 MYO6 TMOD3 TMOD3 MOK MOK SPTA1 SPTA1 ESPN ESPN SH3PXD2B SH3PXD2B LOC102161120 LOC102161120 ABLIM3 ABLIM3 MYH3 MYH3 ACKR2 ACKR2 ACTN2 ACTN2 TNNI3 TNNI3 DAAM2 DAAM2 CAPZA2 CAPZA2 A0A5G2QF80_PIG A0A5G2QF80_PIG ACTR3B ACTR3B KIF9 KIF9 KNCN KNCN WASL WASL MYH8 MYH8 MYL6 MYL6 SWAP70 SWAP70 FERMT3 FERMT3 GAS2L2 GAS2L2 MARCKS MARCKS A0A287BQQ6_PIG A0A287BQQ6_PIG H1-0 H1-0 FSCN2 FSCN2 KRT14 KRT14 FLNB FLNB ACTA1 ACTA1 SIPA1L3 SIPA1L3 SMTNL1 SMTNL1 TMOD2 TMOD2 MYO1B MYO1B RTKN RTKN DBN1 DBN1 LIMK2 LIMK2 ABL1 ABL1 FMN1 FMN1 CCDC88A CCDC88A MYH11 MYH11 FBLIM1 FBLIM1 ROM1 ROM1 TNNT3 TNNT3 SPTBN2 SPTBN2 ASAP1 ASAP1 WAS WAS MPRIP MPRIP TNNC2 TNNC2 LANCL3 LANCL3 MYH1 MYH1 FMN2 FMN2 MYH7B MYH7B MYO19 MYO19 ABL2 ABL2 TNNI2 TNNI2 MYO15B MYO15B MYO1D MYO1D HSP90AA1 HSP90AA1 LANCL2 LANCL2 BMF BMF RFLNB RFLNB LIMCH1 LIMCH1 DDX58 DDX58 PVALEF PVALEF CNN2 CNN2 TRIOBP TRIOBP BICD2 BICD2 TNNC1 TNNC1 GAS7 GAS7 PAICS PAICS NEBL NEBL LOC100737030 LOC100737030 YME1L1 YME1L1 PDCD6IP PDCD6IP WIPF1 WIPF1 SCIN SCIN TPM2 TPM2 NKX2-5 NKX2-5 DAB2 DAB2 SHROOM4 SHROOM4 LASP1 LASP1 TPM4 TPM4 MYO1G MYO1G FILIP1 FILIP1 ACTN4 ACTN4 APMAP APMAP GSN GSN DCTN6 DCTN6 RHOQ RHOQ RFLNA RFLNA MYO1A MYO1A SPTB SPTB ARPC2 ARPC2 SPATA17 SPATA17 SPTAN1 SPTAN1 ACTR2 ACTR2 ARPC4 ARPC4 SH3PXD2A SH3PXD2A CARMIL1 CARMIL1 A0A286ZVA3_PIG A0A286ZVA3_PIG ACTB ACTB A0A286ZUD7_PIG A0A286ZUD7_PIG CDC42BPB CDC42BPB WDR1 WDR1 MYL2 MYL2 AFAP1 AFAP1 ADD1 ADD1 ARPC1B ARPC1B TMOD4 TMOD4 DCTN5 DCTN5 SPTBN1 SPTBN1 SORBS1 SORBS1 SPTBN4 SPTBN4 TNNI1 TNNI1 AMOT AMOT SRC SRC FYB1 FYB1 GDPD2 GDPD2 CFL1 CFL1 TNNT2 TNNT2 LPXN LPXN ACTN1 ACTN1 DCTN4 DCTN4 GAS2 GAS2 AVIL AVIL ACTR10 ACTR10 I3LER3_PIG I3LER3_PIG TRIP6 TRIP6 MYL5 MYL5 CORO1C CORO1C BIN2 BIN2 P3H1 P3H1 RHOU RHOU CARMIL2 CARMIL2 MYH15 MYH15 CALD1 CALD1 ADD2 ADD2 MYH13 MYH13 MYH10 MYH10 F1RN91_PIG F1RN91_PIG MYL4 MYL4 ANLN ANLN LMOD2 LMOD2 SSMEM1 SSMEM1 ZYX ZYX SPATA3 SPATA3 NYAP2 NYAP2 VIL1 VIL1 RUFY4 RUFY4 MYL1 MYL1 ACTR3 ACTR3 F1SF13_PIG F1SF13_PIG ARPC5 ARPC5 MYO7A MYO7A PDLIM4 PDLIM4 MYO9B MYO9B PEAK3 PEAK3 TMSB15B TMSB15B POF1B POF1B TWF2 TWF2 MYL3 MYL3 DCTN3 DCTN3 C10orf90 C10orf90 ABLIM1 ABLIM1 VCL VCL SMTN SMTN MYO18B MYO18B MYO1H MYO1H ARPC3 ARPC3 AUH AUH MYO16 MYO16 LCP1 LCP1 KLHL2 KLHL2 PLEKHH2 PLEKHH2 ARPC1A ARPC1A F1SER7_PIG F1SER7_PIG F1SER8_PIG F1SER8_PIG CAPZA1 CAPZA1 IQGAP3 IQGAP3 PRRC2B PRRC2B ARPC5L ARPC5L DAAM1 DAAM1 ACTC1 ACTC1 SPTBN5 SPTBN5 MYO5A MYO5A EZR EZR MYL12A MYL12A FHL3 FHL3 CAPZB CAPZB UBR7 UBR7 ISM2 ISM2 CFL2 CFL2 PEAK1 PEAK1 F1RMG9_PIG F1RMG9_PIG DEF6 DEF6
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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SYNPOSynaptopodin. (883 aa)
TPM3Tropomyosin alpha-3 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments; Belongs to the tropomyosin family. (303 aa)
CD2APCD2 associated protein. (643 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2069 aa)
DCTN2Dynactin subunit 2. (408 aa)
CDC42EP3CDC42 effector protein 3. (254 aa)
MYO1EMyosin IE; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1116 aa)
MYL9Myosin regulatory light polypeptide 9; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion. (176 aa)
MYO5BUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1845 aa)
MYLPFMyosin light chain, phosphorylatable, fast skeletal muscle. (209 aa)
AFAP1L1Uncharacterized protein. (762 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (525 aa)
MYO1FMyosin IF; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1122 aa)
MYH7Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2052 aa)
DYNLL2Dynein light chain. (133 aa)
SNX9Sorting nexin 9. (632 aa)
TNNT1Troponin T, slow skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. (298 aa)
CTTNCortactin. (685 aa)
MYADMMyeloid associated differentiation marker. (391 aa)
MYO6Unconventional myosin-VI; Myosins are actin-based motor molecules with ATPase activity (By similarity). Unconventional myosins serve in intracellular movements (By similarity). Myosin 6 is a reverse-direction motor protein that moves towards the minus-end of actin filaments (By similarity). Has slow rate of actin-activated ADP release due to weak ATP binding. Functions in a variety of intracellular processes such as vesicular membrane trafficking and cell migration. Required for the structural integrity of the Golgi apparatus via the p53-dependent pro-survival pathway (By similarity). [...] (1285 aa)
TMOD3Uncharacterized protein. (386 aa)
MOKMOK protein kinase; Belongs to the protein kinase superfamily. (464 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2417 aa)
ESPNEspin. (1363 aa)
SH3PXD2BSH3 and PX domains 2B. (958 aa)
LOC102161120Uncharacterized protein. (392 aa)
ABLIM3Actin binding LIM protein family member 3. (694 aa)
MYH3Myosin heavy chain 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1986 aa)
ACKR2Atypical chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (385 aa)
ACTN2Uncharacterized protein. (933 aa)
TNNI3Troponin I3, cardiac type. (273 aa)
DAAM2Dishevelled associated activator of morphogenesis 2. (1075 aa)
CAPZA2F-actin-capping protein subunit alpha-2; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). (286 aa)
A0A5G2QF80_PIGUncharacterized protein. (287 aa)
ACTR3BUncharacterized protein; Belongs to the actin family. (463 aa)
KIF9Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (885 aa)
KNCNKinocilin. (130 aa)
WASLWASP like actin nucleation promoting factor. (511 aa)
MYH8Myosin-4; Muscle contraction. (1940 aa)
MYL6Myosin light polypeptide 6; Regulatory light chain of myosin. Does not bind calcium. (278 aa)
SWAP70Switching B cell complex subunit SWAP70. (585 aa)
FERMT3Fermitin family member 3. (667 aa)
GAS2L2Growth arrest specific 2 like 2. (876 aa)
MARCKSMyristoylated alanine rich protein kinase C substrate. (332 aa)
A0A287BQQ6_PIGMyosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1388 aa)
H1-0H1 histone family member 0. (194 aa)
FSCN2Fascin actin-bundling protein 2, retinal. (556 aa)
KRT14Keratin 14; Belongs to the intermediate filament family. (515 aa)
FLNBFilamin B. (2633 aa)
ACTA1Actin, alpha skeletal muscle. (465 aa)
SIPA1L3SPAR_C domain-containing protein. (718 aa)
SMTNL1Calponin-homology (CH) domain-containing protein. (182 aa)
TMOD2Tropomodulin 2. (351 aa)
MYO1BMyosin IB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1136 aa)
RTKNRhotekin. (564 aa)
DBN1Drebrin 1. (857 aa)
LIMK2LIM domain kinase 2. (793 aa)
ABL1Tyrosine-protein kinase. (1146 aa)
FMN1Formin 1. (1195 aa)
CCDC88ACoiled-coil domain containing 88A. (1873 aa)
MYH11Myosin-11; Muscle contraction. (1761 aa)
FBLIM1Filamin binding LIM protein 1. (415 aa)
ROM1Retinal outer segment membrane protein 1. (351 aa)
TNNT3Troponin T, fast skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. (438 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2423 aa)
ASAP1Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform 1. (1129 aa)
WASWASP actin nucleation promoting factor. (500 aa)
MPRIPMyosin phosphatase Rho interacting protein. (1138 aa)
TNNC2Troponin C, skeletal muscle; Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. (211 aa)
LANCL3LanC like 3. (420 aa)
MYH1Myosin-2; Muscle contraction. Required for cytoskeleton organization (By similarity). (1956 aa)
FMN2FH2 domain-containing protein. (198 aa)
MYH7BMyosin heavy chain 7B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1748 aa)
MYO19Myosin XIX; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1005 aa)
ABL2Tyrosine-protein kinase. (1096 aa)
TNNI2Uncharacterized protein. (249 aa)
MYO15BUncharacterized protein. (700 aa)
MYO1DMyosin ID; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1006 aa)
HSP90AA1Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] (789 aa)
LANCL2LanC like 2. (486 aa)
BMFBcl2 modifying factor. (183 aa)
RFLNBRefilin-B. (219 aa)
LIMCH1LIM and calponin homology domains 1. (1469 aa)
DDX58Antiviral innate immune response receptor RIG-I; Innate immune receptor that senses cytoplasmic viral nucleic acids and activates a downstream signaling cascade leading to the production of type I interferons and proinflammatory cytokines. Forms a ribonucleoprotein complex with viral RNAs on which it homooligomerizes to form filaments. The homooligomerization allows the recruitment of RNF135 an E3 ubiquitin-protein ligase that activates and amplifies the RIG-I-mediated antiviral signaling in an RNA length-dependent manner through ubiquitination-dependent and -independent mechanisms. Up [...] (943 aa)
PVALEFParvalbumin like EF-hand containing. (132 aa)
CNN2Calponin-2; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (396 aa)
TRIOBPTRIO and F-actin binding protein. (2043 aa)
BICD2Protein bicaudal D homolog 2 isoform 1. (836 aa)
TNNC1Troponin C, slow skeletal and cardiac muscles; Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. (184 aa)
GAS7Growth arrest specific 7. (519 aa)
PAICSAIRC domain-containing protein. (425 aa)
NEBLNebulette isoform 1. (1013 aa)
LOC100737030IF rod domain-containing protein; Belongs to the intermediate filament family. (452 aa)
YME1L1ANK_REP_REGION domain-containing protein. (2031 aa)
PDCD6IPBRO1 domain-containing protein. (878 aa)
WIPF1WH2 domain-containing protein. (515 aa)
SCINAdseverin; Ca(2+)-dependent actin filament-severing protein that has a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Severing activity is inhibited by phosphatidylinositol 4,5-bis- phosphate (PIP2) (By similarity). Required for megakaryocyte differentiation, maturation, polyploidization and apoptosis with the release of platelet-like particles (By similarity). Plays a role in osteoclastogenesis (OCG) and actin cytoskel [...] (715 aa)
TPM2Uncharacterized protein; Belongs to the tropomyosin family. (359 aa)
NKX2-5NK2 homeobox 5. (323 aa)
DAB2DAB adaptor protein 2. (769 aa)
SHROOM4Shroom family member 4. (1564 aa)
LASP1LIM and SH3 domain protein 1; Plays an important role in the regulation of dynamic actin- based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity). (280 aa)
TPM4Tropomyosin alpha-4 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium. (284 aa)
MYO1GMyosin IG; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (983 aa)
FILIP1Filamin-A-interacting protein 1 isoform X1. (1216 aa)
ACTN4Actinin alpha 4. (1160 aa)
APMAPAdipocyte plasma membrane associated protein. (622 aa)
GSNGelsolin; Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis (By similarity). Belongs to the villin/gelsolin family. (780 aa)
DCTN6Dynactin 6. (190 aa)
RHOQRho-related GTP-binding protein RhoQ. (205 aa)
RFLNAUncharacterized protein. (266 aa)
MYO1AMyosin IA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1043 aa)
SPTBSpectrin beta chain; Belongs to the spectrin family. (2340 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (273 aa)
SPATA17Spermatogenesis associated 17. (362 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2390 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (404 aa)
ARPC4Actin related protein 2/3 complex subunit 4. (231 aa)
SH3PXD2ASH3 and PX domain-containing protein 2A. (1133 aa)
CARMIL1Capping protein regulator and myosin 1 linker 1. (1429 aa)
A0A286ZVA3_PIGCCDC144C domain-containing protein. (323 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
A0A286ZUD7_PIGUncharacterized protein. (92 aa)
CDC42BPBSerine/threonine-protein kinase MRCK beta isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1712 aa)
WDR1WD repeat-containing protein 1 isoform 1. (606 aa)
MYL2Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. (166 aa)
AFAP1Uncharacterized protein. (829 aa)
ADD1Adducin 1. (786 aa)
ARPC1BActin related protein 2/3 complex subunit 1B. (440 aa)
TMOD4Tropomodulin-4 isoform X1. (345 aa)
DCTN5Dynactin subunit 5. (182 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2365 aa)
SORBS1Sorbin and SH3 domain containing 1. (1718 aa)
SPTBN4Spectrin beta, non-erythrocytic 4. (2617 aa)
TNNI1Troponin I1, slow skeletal type. (228 aa)
AMOTAngiomotin isoform X1. (1088 aa)
SRCTyrosine-protein kinase. (559 aa)
FYB1FYN binding protein 1. (837 aa)
GDPD2Glycerophosphodiester phosphodiesterase domain containing 2. (569 aa)
CFL1Cofilin-1; Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up- regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. Required for neural tube morphogenesis and neural crest cell migration (By similarity). (179 aa)
TNNT2Uncharacterized protein. (295 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (386 aa)
ACTN1Uncharacterized protein. (888 aa)
DCTN4Dynactin subunit 4. (501 aa)
GAS2Growth arrest specific 2. (325 aa)
AVILAdvillin isoform X1. (816 aa)
ACTR10Actin-related protein 10; Belongs to the actin family. (417 aa)
I3LER3_PIGUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (217 aa)
TRIP6Thyroid hormone receptor interactor 6. (481 aa)
MYL5Myosin light chain 5. (174 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (511 aa)
BIN2Bridging integrator 2. (512 aa)
P3H1Prolyl 3-hydroxylase 1 isoform 1. (698 aa)
RHOURas homolog family member U. (258 aa)
CARMIL2Capping protein regulator and myosin 1 linker 2. (1406 aa)
MYH15Myosin heavy chain 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1934 aa)
CALD1Caldesmon 1. (801 aa)
ADD2Adducin 2. (725 aa)
MYH13Myosin heavy chain 13; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1938 aa)
MYH10Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (947 aa)
F1RN91_PIGMyosin_tail_1 domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1234 aa)
MYL4Myosin light chain 4; Regulatory light chain of myosin. Does not bind calcium. (197 aa)
ANLNAnillin actin binding protein. (1144 aa)
LMOD2Leiomodin 2. (550 aa)
SSMEM1Serine rich single-pass membrane protein 1. (244 aa)
ZYXZyxin. (588 aa)
SPATA3Uncharacterized protein. (490 aa)
NYAP2Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2. (719 aa)
VIL1Villin-1; Epithelial cell-specific Ca(2+)-regulated actin-modifying protein that modulates the reorganization of microvillar actin filaments. Plays a role in the actin nucleation, actin filament bundle assembly, actin filament capping and severing. Binds phosphatidylinositol 4,5-bisphosphate (PIP2) and lysophosphatidic acid (LPA); binds LPA with higher affinity than PIP2. Binding to LPA increases its phosphorylation by SRC and inhibits all actin-modifying activities. Binding to PIP2 inhibits actin-capping and -severing activities but enhances actin-bundling activity. Regulates the inte [...] (826 aa)
RUFY4RUN and FYVE domain containing 4. (571 aa)
MYL1Uncharacterized protein. (316 aa)
ACTR3Actin related protein 3; Belongs to the actin family. (422 aa)
F1SF13_PIGCobl domain-containing protein. (406 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
MYO7AUnconventional myosin-VIIa; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. In the retina, plays an important role in the renewal of the outer photoreceptor disks. Plays an important role in the distribution and migration of retinal pigment epithelial (RPE) melanosomes and phagosomes, and in the regulation of opsin transport in retinal photoreceptors. In the inner ear, plays an important role in differenti [...] (2213 aa)
PDLIM4PDZ and LIM domain protein 4 isoform 1. (331 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2194 aa)
PEAK3PEAK family member 3. (466 aa)
TMSB15BThymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (45 aa)
POF1BPOF1B actin binding protein. (589 aa)
TWF2Twinfilin actin binding protein 2. (500 aa)
MYL3Uncharacterized protein. (196 aa)
DCTN3Dynactin subunit 3 isoform 1. (186 aa)
C10orf90Chromosome 10 open reading frame 90. (648 aa)
ABLIM1Actin binding LIM protein 1. (836 aa)
VCLVinculin; Actin filament (F-actin)-binding protein involved in cell- matrix adhesion and cell-cell adhesion. Regulates cell-surface E- cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion; Belongs to the vinculin/alpha-catenin family. (1135 aa)
SMTNCalponin-homology (CH) domain-containing protein. (935 aa)
MYO18BMyosin XVIIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2444 aa)
MYO1HMyosin IH; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1038 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
AUHMethylglutaconyl-CoA hydratase, mitochondrial isoform X1; Belongs to the enoyl-CoA hydratase/isomerase family. (338 aa)
MYO16Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (940 aa)
LCP1Lymphocyte cytosolic protein 1. (642 aa)
KLHL2Kelch like family member 2. (593 aa)
PLEKHH2Pleckstrin homology, MyTH4 and FERM domain containing H2. (1553 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
F1SER7_PIGANK_REP_REGION domain-containing protein. (858 aa)
F1SER8_PIGANK_REP_REGION domain-containing protein. (697 aa)
CAPZA1F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (294 aa)
IQGAP3IQ motif containing GTPase activating protein 3. (1696 aa)
PRRC2BProline rich coiled-coil 2B. (2241 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (303 aa)
DAAM1Dishevelled associated activator of morphogenesis 1. (1086 aa)
ACTC1Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. (377 aa)
SPTBN5Spectrin beta, non-erythrocytic 5. (3616 aa)
MYO5AUnconventional myosin-Va isoform X3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1877 aa)
EZREzrin. (562 aa)
MYL12AMyosin regulatory light chain 12A isoform 2. (178 aa)
FHL3Four and a half LIM domains 3. (290 aa)
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity). (342 aa)
UBR7UBR-type domain-containing protein. (393 aa)
ISM2AMOP domain-containing protein. (422 aa)
CFL2Cofilin-2; Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Required for muscle maintenance. May play a role during the exchange of alpha-actin forms during the early postnatal remodeling of the sarcomere (By similarity). (166 aa)
PEAK1Pseudopodium enriched atypical kinase 1. (1748 aa)
F1RMG9_PIGUncharacterized protein. (298 aa)
DEF6Differentially expressed in FDCP 6 homolog. (631 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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