STRINGSTRING
IFFO1 IFFO1 BLM BLM CFL2 CFL2 LGALS13 LGALS13 GFI1B GFI1B RUNX1T1 RUNX1T1 GFI1 GFI1 GMCL1 GMCL1 NCOR2 NCOR2 ZNF503 ZNF503 SATB1 SATB1 OGG1 OGG1 TENM1 TENM1 AKAP8 AKAP8 AKAP8L AKAP8L LMNB1 LMNB1 MATR3 MATR3 ZNF703 ZNF703 SNW1 SNW1 CAD CAD IFFO2 IFFO2 SATB2 SATB2 CFL1 CFL1 ALOX5 ALOX5 MORC2 MORC2 HNRNPU HNRNPU A0A287AAB7_PIG A0A287AAB7_PIG DNMT3B DNMT3B KIN KIN LMNA LMNA NSMF NSMF TGFB1I1 TGFB1I1 LOC110257676 LOC110257676 ATN1 ATN1 VDR VDR DCAF7 DCAF7 NONO NONO ATXN1 ATXN1 XPOT XPOT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IFFO1Intermediate filament family orphan 1; Belongs to the intermediate filament family. (571 aa)
BLMBLM RecQ like helicase. (1432 aa)
CFL2Cofilin-2; Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Required for muscle maintenance. May play a role during the exchange of alpha-actin forms during the early postnatal remodeling of the sarcomere (By similarity). (166 aa)
LGALS13Galectin. (138 aa)
GFI1BGrowth factor independent 1B transcriptional repressor. (436 aa)
RUNX1T1RUNX1 partner transcriptional co-repressor 1. (604 aa)
GFI1Growth factor independent 1 transcriptional repressor. (416 aa)
GMCL1BTB domain-containing protein. (513 aa)
NCOR2Uncharacterized protein. (2450 aa)
ZNF503Zinc finger protein 503. (645 aa)
SATB1DNA-binding protein SATB. (751 aa)
OGG1OGG_N domain-containing protein. (195 aa)
TENM1Teneurin transmembrane protein 1. (2732 aa)
AKAP8A-kinase anchoring protein 8; Belongs to the AKAP95 family. (690 aa)
AKAP8LA-kinase anchoring protein 8 like; Belongs to the AKAP95 family. (644 aa)
LMNB1Lamin-B1 isoform 1; Belongs to the intermediate filament family. (586 aa)
MATR3Uncharacterized protein. (897 aa)
ZNF703Zinc finger protein 703. (591 aa)
SNW1SNW domain-containing protein 1 isoform 2. (536 aa)
CADCarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2205 aa)
IFFO2Intermediate filament family orphan 2; Belongs to the intermediate filament family. (514 aa)
SATB2DNA-binding protein SATB. (733 aa)
CFL1Cofilin-1; Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up- regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. Required for neural tube morphogenesis and neural crest cell migration (By similarity). (179 aa)
ALOX5Arachidonate 5-lipoxygenase. (638 aa)
MORC2MORC family CW-type zinc finger protein 2 isoform X2. (1038 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U isoform a. (825 aa)
A0A287AAB7_PIGBTB domain-containing protein. (471 aa)
DNMT3BDNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (856 aa)
KINKin17 DNA and RNA binding protein. (392 aa)
LMNAPrelamin-A/C; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation. Required for osteoblastogenesis and bone formation. A [...] (704 aa)
NSMFNMDA receptor synaptonuclear signaling and neuronal migration factor. (532 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (519 aa)
LOC110257676BTB domain-containing protein. (513 aa)
ATN1Atrophin-1. (1182 aa)
VDRVitamin D3 receptor; Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells (By similarity). Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR (By similarity). The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes (By similarity). Plays a central role in calcium homeostasis (By similarity). (520 aa)
DCAF7DDB1 and CUL4 associated factor 7. (340 aa)
NONONon-POU domain containing octamer binding. (705 aa)
ATXN1Ataxin-1 ATXN1. (821 aa)
XPOTExportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (1016 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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