STRINGSTRING
CD27 CD27 F1S987_PIG F1S987_PIG F1S6W1_PIG F1S6W1_PIG F1S6U2_PIG F1S6U2_PIG F1S6S1_PIG F1S6S1_PIG SPPL2A SPPL2A SERPINB7 SERPINB7 MORN5 MORN5 LOC100523213 LOC100523213 IL5 IL5 IL4 IL4 IL10 IL10 F6Q8R7_PIG F6Q8R7_PIG TRBV19 TRBV19 CD79B CD79B CD4 CD4 TRAV36DV7 TRAV36DV7 I3LA20_PIG I3LA20_PIG I3LAQ5_PIG I3LAQ5_PIG TRDC TRDC I3LI31_PIG I3LI31_PIG IL6 IL6 SERPINB11 SERPINB11 I3LMR4_PIG I3LMR4_PIG I3LT74_PIG I3LT74_PIG A0A075B7I5_PIG A0A075B7I5_PIG IL13 IL13 A0A075B7I9_PIG A0A075B7I9_PIG A0A286ZJL9_PIG A0A286ZJL9_PIG A0A286ZK50_PIG A0A286ZK50_PIG A0A286ZL89_PIG A0A286ZL89_PIG A0A286ZM13_PIG A0A286ZM13_PIG A0A286ZP42_PIG A0A286ZP42_PIG SYK SYK A0A286ZQH2_PIG A0A286ZQH2_PIG A0A286ZQB7_PIG A0A286ZQB7_PIG A0A286ZRA4_PIG A0A286ZRA4_PIG A0A286ZTC9_PIG A0A286ZTC9_PIG A0A286ZXF8_PIG A0A286ZXF8_PIG IFNG IFNG A0A286ZYJ0_PIG A0A286ZYJ0_PIG A0A287A3Q4_PIG A0A287A3Q4_PIG LOC100623670 LOC100623670 A0A287A4Y3_PIG A0A287A4Y3_PIG A0A287A9X3_PIG A0A287A9X3_PIG A0A287AC24_PIG A0A287AC24_PIG PIGR PIGR A0A287AI00_PIG A0A287AI00_PIG TRAV4 TRAV4 A0A287AM45_PIG A0A287AM45_PIG A0A287ANX9_PIG A0A287ANX9_PIG A0A287AQB3_PIG A0A287AQB3_PIG CDR2 CDR2 A0A287AT33_PIG A0A287AT33_PIG POLN POLN A0A287AYC4_PIG A0A287AYC4_PIG LOC102166266 LOC102166266 A0A287AZS3_PIG A0A287AZS3_PIG FCGR3A FCGR3A HIF1A HIF1A A0A287B5S5_PIG A0A287B5S5_PIG A0A287B5X7_PIG A0A287B5X7_PIG A0A287B8C0_PIG A0A287B8C0_PIG A0A287BAK4_PIG A0A287BAK4_PIG A0A287BA55_PIG A0A287BA55_PIG A0A287BAB3_PIG A0A287BAB3_PIG ALB ALB LOC106508706 LOC106508706 A0A287BCF7_PIG A0A287BCF7_PIG LOC100153783 LOC100153783 TRAV16 TRAV16 A0A287BLH9_PIG A0A287BLH9_PIG A0A287BPA6_PIG A0A287BPA6_PIG A0A287BPL5_PIG A0A287BPL5_PIG A0A287BQ00_PIG A0A287BQ00_PIG LAC_PIG LAC_PIG A0A287BNX9_PIG A0A287BNX9_PIG JCHAIN JCHAIN A0A287BRE1_PIG A0A287BRE1_PIG A0A287BT33_PIG A0A287BT33_PIG CD79A CD79A A0A5G2QSM7_PIG A0A5G2QSM7_PIG A0A5G2QU02_PIG A0A5G2QU02_PIG A0A5G2QDC4_PIG A0A5G2QDC4_PIG A0A5G2QL02_PIG A0A5G2QL02_PIG A0A5G2QH11_PIG A0A5G2QH11_PIG A0A5G2QKP2_PIG A0A5G2QKP2_PIG A0A5G2QJS4_PIG A0A5G2QJS4_PIG A0A5G2RAH4_PIG A0A5G2RAH4_PIG SPN SPN CCL25 CCL25 A0A5G2R4N2_PIG A0A5G2R4N2_PIG A0A5G2R5H2_PIG A0A5G2R5H2_PIG TRBV27 TRBV27 LOC110261595 LOC110261595 A0A5G2REU4_PIG A0A5G2REU4_PIG ENSSSCP00000073954 ENSSSCP00000073954
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CD27CD27. (249 aa)
F1S987_PIGIg-like domain-containing protein. (117 aa)
F1S6W1_PIGIg-like domain-containing protein. (180 aa)
F1S6U2_PIGIg-like domain-containing protein. (149 aa)
F1S6S1_PIGIg-like domain-containing protein. (199 aa)
SPPL2ASignal peptide peptidase like 2A. (694 aa)
SERPINB7Serpin family B member 7; Belongs to the serpin family. (380 aa)
MORN5Uncharacterized protein. (188 aa)
LOC100523213Ig-like domain-containing protein. (212 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (133 aa)
IL10Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (219 aa)
F6Q8R7_PIGIg-like domain-containing protein. (311 aa)
TRBV19T cell receptor beta variable 19. (127 aa)
CD79BCD79b molecule. (228 aa)
CD4CD4 molecule. (494 aa)
TRAV36DV7T cell receptor alpha variable 36/delta variable 7. (135 aa)
I3LA20_PIGIg-like domain-containing protein. (129 aa)
I3LAQ5_PIGIg-like domain-containing protein. (164 aa)
TRDCT cell receptor delta constant. (167 aa)
I3LI31_PIGIg-like domain-containing protein. (144 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (241 aa)
SERPINB11Serpin family B member 11 (gene/pseudogene); Belongs to the serpin family. (392 aa)
I3LMR4_PIGIg-like domain-containing protein. (144 aa)
I3LT74_PIGUncharacterized protein. (130 aa)
A0A075B7I5_PIGIg-like domain-containing protein. (111 aa)
IL13Interleukin-13; Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macrophages. (131 aa)
A0A075B7I9_PIGIg-like domain-containing protein. (155 aa)
A0A286ZJL9_PIGUncharacterized protein. (498 aa)
A0A286ZK50_PIGIGv domain-containing protein. (135 aa)
A0A286ZL89_PIGUncharacterized protein. (342 aa)
A0A286ZM13_PIGIg-like domain-containing protein. (185 aa)
A0A286ZP42_PIGIGv domain-containing protein. (147 aa)
SYK40 kDa tyrosine-protein kinase SYK; Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the recepto [...] (628 aa)
A0A286ZQH2_PIGIg-like domain-containing protein. (111 aa)
A0A286ZQB7_PIGIg-like domain-containing protein. (167 aa)
A0A286ZRA4_PIGIg-like domain-containing protein. (155 aa)
A0A286ZTC9_PIGUncharacterized protein. (647 aa)
A0A286ZXF8_PIGUncharacterized protein. (183 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (166 aa)
A0A286ZYJ0_PIGIGv domain-containing protein. (127 aa)
A0A287A3Q4_PIGIg-like domain-containing protein. (177 aa)
LOC100623670Ig-like domain-containing protein. (315 aa)
A0A287A4Y3_PIGIg-like domain-containing protein. (226 aa)
A0A287A9X3_PIGIGv domain-containing protein. (120 aa)
A0A287AC24_PIGIg-like domain-containing protein. (112 aa)
PIGRPolymeric immunoglobulin receptor; This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface (By similarity). (792 aa)
A0A287AI00_PIGIg-like domain-containing protein. (153 aa)
TRAV4T cell receptor alpha variable 4. (105 aa)
A0A287AM45_PIGIg-like domain-containing protein. (282 aa)
A0A287ANX9_PIGUncharacterized protein. (472 aa)
A0A287AQB3_PIGIg-like domain-containing protein. (203 aa)
CDR2Cerebellar degeneration related protein 2. (456 aa)
A0A287AT33_PIGIg-like domain-containing protein. (173 aa)
POLNDNA polymerase nu. (900 aa)
A0A287AYC4_PIGIg-like domain-containing protein. (110 aa)
LOC102166266Ig-like domain-containing protein. (227 aa)
A0A287AZS3_PIGIg-like domain-containing protein. (223 aa)
FCGR3ALow affinity immunoglobulin gamma Fc region receptor III; Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. (259 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform 1. (824 aa)
A0A287B5S5_PIGUncharacterized protein. (141 aa)
A0A287B5X7_PIGIg-like domain-containing protein. (152 aa)
A0A287B8C0_PIGIGv domain-containing protein. (179 aa)
A0A287BAK4_PIGIGv domain-containing protein. (180 aa)
A0A287BA55_PIGIg-like domain-containing protein. (175 aa)
A0A287BAB3_PIGIg-like domain-containing protein. (169 aa)
ALBSerum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] (659 aa)
LOC106508706Ig-like domain-containing protein. (161 aa)
A0A287BCF7_PIGIg-like domain-containing protein. (124 aa)
LOC100153783Ovalbumin isoform X1; Belongs to the serpin family. (385 aa)
TRAV16T cell receptor alpha variable 16. (166 aa)
A0A287BLH9_PIGUncharacterized protein. (221 aa)
A0A287BPA6_PIGIg-like domain-containing protein. (130 aa)
A0A287BPL5_PIGIg-like domain-containing protein. (154 aa)
A0A287BQ00_PIGIg-like domain-containing protein. (194 aa)
LAC_PIGIg lambda chain C region. (380 aa)
A0A287BNX9_PIGIg-like domain-containing protein. (111 aa)
JCHAINJoining chain of multimeric IgA and IgM. (186 aa)
A0A287BRE1_PIGIg-like domain-containing protein. (112 aa)
A0A287BT33_PIGIg-like domain-containing protein. (153 aa)
CD79AIg-like domain-containing protein. (234 aa)
A0A5G2QSM7_PIGIg-like domain-containing protein. (147 aa)
A0A5G2QU02_PIGIg-like domain-containing protein. (133 aa)
A0A5G2QDC4_PIGIg-like domain-containing protein. (133 aa)
A0A5G2QL02_PIGIg-like domain-containing protein. (182 aa)
A0A5G2QH11_PIGIGv domain-containing protein. (138 aa)
A0A5G2QKP2_PIGIg-like domain-containing protein. (124 aa)
A0A5G2QJS4_PIGUncharacterized protein. (79 aa)
A0A5G2RAH4_PIGIg-like domain-containing protein. (123 aa)
SPNUncharacterized protein. (463 aa)
CCL25C-C motif chemokine 25; Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4 (By similarity); Belongs to the intercrine beta (chemokine CC) family. (220 aa)
A0A5G2R4N2_PIGIg-like domain-containing protein. (147 aa)
A0A5G2R5H2_PIGUncharacterized protein. (261 aa)
TRBV27T cell receptor beta variable 27. (146 aa)
LOC110261595Ig-like domain-containing protein. (290 aa)
A0A5G2REU4_PIGIg-like domain-containing protein. (227 aa)
ENSSSCP00000073954annotation not available (182 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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