STRINGSTRING
KIF1A KIF1A ACHE ACHE FKBP4 FKBP4 CPLX1 CPLX1 SPAST SPAST LRIG2 LRIG2 KIF3A KIF3A CXADR CXADR RIMS2 RIMS2 APBB1 APBB1 RUNDC1 RUNDC1 TGFB2 TGFB2 NAV1 NAV1 KLK11 KLK11 AUTS2 AUTS2 NTRK3 NTRK3 SLC9A6 SLC9A6 DLG4 DLG4 CRHR2 CRHR2 A0A5G2R6G8_PIG A0A5G2R6G8_PIG GAP43 GAP43 SSTR3 SSTR3 MYO1D MYO1D BDNF BDNF MAPK8IP1 MAPK8IP1 RHOA RHOA EPB41L3 EPB41L3 BASP1 BASP1 CPLX2 CPLX2 IGF2BP3 IGF2BP3 ERMN ERMN ALS2 ALS2 NDRG2 NDRG2 LAMP5 LAMP5 GHRH GHRH PRSS12 PRSS12 NEFH NEFH SHTN1 SHTN1 BAG3 BAG3 SYT2 SYT2 C1QL3 C1QL3 CPNE4 CPNE4 CCK CCK GHRL GHRL TMEM108 TMEM108 PENK PENK TRPA1 TRPA1 CALB1 CALB1 KCNQ3 KCNQ3 FMR1 FMR1 SPTBN4 SPTBN4 SNCA SNCA SLC18A3 SLC18A3 SLC38A7 SLC38A7 KCNB1 KCNB1 KLK8 KLK8 ACTB ACTB RIMBP2 RIMBP2 ADGRL1 ADGRL1 CACNG2 CACNG2 MYO9A MYO9A MAPK8IP3 MAPK8IP3 LOC100524773 LOC100524773 UNC5C UNC5C SLC4A8 SLC4A8 OPRL1 OPRL1 NFIB NFIB KIAA0895L KIAA0895L NEO1 NEO1 SSTR5 SSTR5 TRIM46 TRIM46 ALCAM ALCAM FLRT3 FLRT3 STMN2 STMN2 CFL1 CFL1 I3LTW2_PIG I3LTW2_PIG GPER1 GPER1 DHX36 DHX36 ALDH1A1 ALDH1A1 BLVRB BLVRB SEMA3A SEMA3A PTBP2 PTBP2 RCAN3 RCAN3 OLFM1 OLFM1 KLK15 KLK15 TAOK2 TAOK2 FBRSL1 FBRSL1 GPM6A GPM6A DISC1 DISC1 EPHB1 EPHB1 CRMP1 CRMP1 RUFY3 RUFY3 I3L661_PIG I3L661_PIG FXR2 FXR2 NF1 NF1 SSTR2 SSTR2 GARS1 GARS1 KIAA0895 KIAA0895 EXOC4 EXOC4 PTPRN PTPRN F1SF13_PIG F1SF13_PIG ZPR1 ZPR1 NNMT NNMT DPYSL3 DPYSL3 CRHBP CRHBP SYDE1 SYDE1 PALM3 PALM3 F1S6T5_PIG F1S6T5_PIG DBX1 DBX1 KCNA4 KCNA4 DAGLA DAGLA HAPLN2 HAPLN2 CEND1 CEND1 SYP SYP APP APP SETX SETX DAB2IP DAB2IP OTX2 OTX2 MICAL1 MICAL1 OPRM1 OPRM1 NCMAP NCMAP EPHB2 EPHB2 DVL1 DVL1 ACAP3 ACAP3 KCNA7 KCNA7 LSR LSR CALB2 CALB2 KLC1 KLC1 PSEN1 PSEN1 CPNE6 CPNE6 CPLX3 CPLX3 CIB1 CIB1 NTS NTS KCNA1 KCNA1 KIF5A KIF5A MME MME TOR1A TOR1A NEFL NEFL TRPV1 TRPV1 RCAN2 RCAN2 GLRX GLRX SMIM31 SMIM31 DIP2B DIP2B GAN GAN LRRC7 LRRC7 MBP MBP SCGN SCGN KCNAB1 KCNAB1 NEFM NEFM KLK9 KLK9 L1CAM L1CAM CNTNAP1 CNTNAP1 ZFYVE27 ZFYVE27 NGF NGF DOC2B DOC2B NTF3 NTF3 RESP18 RESP18 PRRT2 PRRT2 CNTN2 CNTN2 ELAVL4 ELAVL4 DBN1 DBN1 A0A287B9Q7_PIG A0A287B9Q7_PIG C1QL1 C1QL1 DCC DCC NECTIN3 NECTIN3 DOC2A DOC2A INMT INMT KCNA2 KCNA2 LRP2 LRP2 PPT1 PPT1 SYAP1 SYAP1 NRSN1 NRSN1 TH TH KCNAB2 KCNAB2 A0A287AT02_PIG A0A287AT02_PIG KCNQ2 KCNQ2 NFASC NFASC AAK1 AAK1 SIRT2 SIRT2 TSPOAP1 TSPOAP1 LGALS4 LGALS4 MGP MGP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KIF1AKinesin family member 1A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1793 aa)
ACHEAcetylcholinesterase (Cartwright blood group); Belongs to the type-B carboxylesterase/lipase family. (765 aa)
FKBP4Peptidylprolyl isomerase. (455 aa)
CPLX1Complexin 1. (133 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (615 aa)
LRIG2Leucine rich repeats and immunoglobulin like domains 2. (1065 aa)
KIF3AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (754 aa)
CXADRUncharacterized protein. (419 aa)
RIMS2Regulating synaptic membrane exocytosis 2. (1348 aa)
APBB1Amyloid beta precursor protein binding family B member 1. (840 aa)
RUNDC1RUN domain-containing protein 1 isoform 1. (613 aa)
TGFB2Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (443 aa)
NAV1Neuron navigator 1. (2165 aa)
KLK11Kallikrein related peptidase 11; Belongs to the peptidase S1 family. (340 aa)
AUTS2Uncharacterized protein. (1255 aa)
NTRK3NT-3 growth factor receptor; Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation. Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily. (864 aa)
SLC9A6Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (679 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (764 aa)
CRHR2Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (482 aa)
A0A5G2R6G8_PIGUncharacterized protein. (157 aa)
GAP43Uncharacterized protein. (244 aa)
SSTR3Somatostatin receptor 3; Belongs to the G-protein coupled receptor 1 family. (421 aa)
MYO1DMyosin ID; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1006 aa)
BDNFBrain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (260 aa)
MAPK8IP1Mitogen-activated protein kinase 8 interacting protein 1. (711 aa)
RHOATransforming protein RhoA isoform 1. (193 aa)
EPB41L3Erythrocyte membrane protein band 4.1 like 3. (1213 aa)
BASP1Uncharacterized protein. (228 aa)
CPLX2Complexin 2. (163 aa)
IGF2BP3Insulin-like growth factor 2 mRNA-binding protein 3. (586 aa)
ERMNErmin isoform b. (282 aa)
ALS2Alsin Rho guanine nucleotide exchange factor ALS2. (1662 aa)
NDRG2Protein NDRG2 isoform a. (371 aa)
LAMP5Lysosomal associated membrane protein family member 5. (280 aa)
GHRHSomatoliberin; GRF is released by the hypothalamus and acts on the adenohypophyse to stimulate the secretion of growth hormone. (106 aa)
PRSS12Serine protease 12; Belongs to the peptidase S1 family. (875 aa)
NEFHNeurofilament heavy polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. NF-H has an important function in mature axons that is not subserved by the two smaller NF proteins. (847 aa)
SHTN1Shootin 1. (631 aa)
BAG3BCL2 associated athanogene 3. (609 aa)
SYT2Synaptotagmin 2. (417 aa)
C1QL3Complement C1q-like protein 3. (255 aa)
CPNE4Copine-4 isoform 1. (575 aa)
CCKCholecystokinin-58 desnonopeptide; This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion. (154 aa)
GHRLAppetite-regulating hormone; Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation (By similarity); Belongs to the motilin family. (118 aa)
TMEM108Transmembrane protein 108. (575 aa)
PENKProenkephalin. (274 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1145 aa)
CALB1Calbindin 1. (261 aa)
KCNQ3Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family. (872 aa)
FMR1Fragile X mental retardation protein 1. (632 aa)
SPTBN4Spectrin beta, non-erythrocytic 4. (2617 aa)
SNCAAlpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] (142 aa)
SLC18A3Solute carrier family 18 member A3. (528 aa)
SLC38A7Solute carrier family 38 member 7. (462 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain, but also in the pancreas and cardiovascular system. Contributes to the regulation of the action potential (AP) repolarization, duration and frequency of repetitive AP firing in neurons, muscle cells and endocrine cells and plays a role in homeostatic attenuation of electrical excitability throughout the brain. Plays also a role in the regulation of exocytosis independently of its electrical function. Forms [...] (858 aa)
KLK8Kallikrein related peptidase 8; Belongs to the peptidase S1 family. (259 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
RIMBP2RIMS-binding protein 2 isoform X2. (1496 aa)
ADGRL1Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family. (1473 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
MYO9AMyosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2647 aa)
MAPK8IP3Mitogen-activated protein kinase 8 interacting protein 3. (1358 aa)
LOC100524773Uncharacterized protein. (2024 aa)
UNC5CUnc-5 netrin receptor C. (937 aa)
SLC4A8Anion exchange protein. (1092 aa)
OPRL1Nociceptin receptor; G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide- binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociceptio [...] (456 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
KIAA0895LKIAA0895 like. (471 aa)
NEO1Neogenin 1. (1465 aa)
SSTR5G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (305 aa)
TRIM46Tripartite motif containing 46. (586 aa)
ALCAMActivated leukocyte cell adhesion molecule. (619 aa)
FLRT3Fibronectin leucine rich transmembrane protein 3. (649 aa)
STMN2Stathmin; Belongs to the stathmin family. (184 aa)
CFL1Cofilin-1; Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up- regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. Required for neural tube morphogenesis and neural crest cell migration (By similarity). (179 aa)
I3LTW2_PIGUncharacterized protein. (175 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (360 aa)
DHX36DEAH (Asp-Glu-Ala-His) box polypeptide 36 tv1. (1012 aa)
ALDH1A1Aldehyde dehydrogenase 1 family member A1; Belongs to the aldehyde dehydrogenase family. (501 aa)
BLVRBFlavin reductase (NADPH). (206 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (800 aa)
PTBP2Polypyrimidine tract binding protein 2. (506 aa)
RCAN3Calcipressin-3 isoform 1. (259 aa)
OLFM1Noelin isoform 4. (485 aa)
KLK15Kallikrein related peptidase 15; Belongs to the peptidase S1 family. (260 aa)
TAOK2TAO kinase 2. (1241 aa)
FBRSL1Fibrosin like 1. (1119 aa)
GPM6AGlycoprotein M6A. (278 aa)
DISC1DISC1 scaffold protein. (819 aa)
EPHB1Ephrin type-B receptor 1. (984 aa)
CRMP1Collapsin response mediator protein 1. (784 aa)
RUFY3RUN and FYVE domain containing 3. (638 aa)
I3L661_PIGUncharacterized protein. (107 aa)
FXR2FMR1 autosomal homolog 2. (667 aa)
NF1Neurofibromin 1. (2847 aa)
SSTR2Somatostatin receptor type 2; Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 [...] (360 aa)
GARS1Glycyl-tRNA synthetase. (745 aa)
KIAA0895KIAA0895. (575 aa)
EXOC4Exocyst complex component 4 tv1. (975 aa)
PTPRNProtein tyrosine phosphatase receptor type N. (978 aa)
F1SF13_PIGCobl domain-containing protein. (406 aa)
ZPR1ZPR1 zinc finger. (455 aa)
NNMTNicotinamide N-methyltransferase; Catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of many drugs and xenobiotic compounds (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family. (264 aa)
DPYSL3Dihydropyrimidinase like 3. (683 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
SYDE1Synapse defective Rho GTPase homolog 1. (735 aa)
PALM3Paralemmin 3. (747 aa)
F1S6T5_PIGUncharacterized protein. (97 aa)
DBX1Developing brain homeobox 1. (343 aa)
KCNA4Potassium voltage-gated channel subfamily A member 4; Belongs to the potassium channel family. (595 aa)
DAGLADiacylglycerol lipase alpha. (1058 aa)
HAPLN2Hyaluronan and proteoglycan link protein 2. (340 aa)
CEND1Cell cycle exit and neuronal differentiation protein 1; Involved in neuronal differentiation. (140 aa)
SYPSynaptophysin. (319 aa)
APPGamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (756 aa)
SETXSenataxin. (2676 aa)
DAB2IPDAB2 interacting protein. (1196 aa)
OTX2Orthodenticle homeobox 2. (297 aa)
MICAL1Microtubule associated monooxygenase, calponin and LIM domain containing 1. (1122 aa)
OPRM1Mu-type opioid receptor; Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP-bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors. The agonist- and cell typ [...] (418 aa)
NCMAPNon-compact myelin associated protein. (102 aa)
EPHB2EPH receptor B2. (987 aa)
DVL1Dishevelled segment polarity protein 1. (700 aa)
ACAP3ArfGAP with coiled-coil, ankyrin repeat and PH domains 3. (833 aa)
KCNA7Potassium voltage-gated channel subfamily A member 7; Belongs to the potassium channel family. (451 aa)
LSRLipolysis stimulated lipoprotein receptor. (598 aa)
CALB2Uncharacterized protein. (348 aa)
KLC1Uncharacterized protein. (677 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (463 aa)
CPNE6Copine 6. (556 aa)
CPLX3Complexin 3. (158 aa)
CIB1Calcium and integrin-binding protein 1 isoform b. (191 aa)
NTSNeurotensin/neuromedin N preproprotein. (171 aa)
KCNA1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
KIF5AKinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1085 aa)
MMENeprilysin; Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. Belongs to the peptidase M13 family. (750 aa)
TOR1ATorsin. (333 aa)
NEFLNeurofilament light polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. (560 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (832 aa)
RCAN2Regulator of calcineurin 2. (243 aa)
GLRXGlutaredoxin-1; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins; Belongs to the glutaredoxin family. (106 aa)
SMIM31Small integral membrane protein 31. (71 aa)
DIP2BDisco interacting protein 2 homolog B. (1575 aa)
GANGigaxonin. (597 aa)
LRRC7Leucine rich repeat containing 7. (1574 aa)
MBPMyelin basic protein; Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity). (295 aa)
SCGNSecretagogin. (278 aa)
KCNAB1Potassium voltage-gated channel subfamily A member regulatory beta subunit 1. (419 aa)
NEFMNeurofilament medium polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. (851 aa)
KLK9Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (307 aa)
L1CAML1 cell adhesion molecule. (1256 aa)
CNTNAP1Contactin associated protein 1. (1384 aa)
ZFYVE27Zinc finger FYVE-type containing 27. (404 aa)
NGFBeta-nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (By similarity). The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone colla [...] (385 aa)
DOC2BDouble C2-like domain-containing protein. (412 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (277 aa)
RESP18RESP18 domain-containing protein. (255 aa)
PRRT2Proline-rich transmembrane protein 2 isoform 3. (406 aa)
CNTN2Contactin 2. (1038 aa)
ELAVL4ELAV-like protein; Belongs to the RRM elav family. (487 aa)
DBN1Drebrin 1. (857 aa)
A0A287B9Q7_PIGCopine domain-containing protein. (113 aa)
C1QL1C1q-related factor. (258 aa)
DCCDCC netrin 1 receptor. (1423 aa)
NECTIN3Nectin cell adhesion molecule 3. (549 aa)
DOC2ADouble C2 domain alpha. (487 aa)
INMTIndolethylamine N-methyltransferase isoform 1. (262 aa)
KCNA2Potassium voltage-gated channel, shaker-related subfamily, member 2; Belongs to the potassium channel family. (499 aa)
LRP2Low-density lipoprotein receptor-related protein 2; Multiligand endocytic receptor (By similarity). Acts together with CUBN to mediate endocytosis of high-density lipoproteins (By similarity). Mediates receptor-mediated uptake of polybasic drugs such as aprotinin, aminoglycosides and polymyxin B (By similarity). In the kidney, mediates the tubular uptake and clearance of leptin (By similarity). Also mediates transport of leptin across the blood-brain barrier through endocytosis at the choroid plexus epithelium (By similarity). Endocytosis of leptin in neuronal cells is required for hyp [...] (4626 aa)
PPT1Palmitoyl-protein thioesterase 1. (305 aa)
SYAP1Synapse-associated protein 1. (358 aa)
NRSN1Neurensin-1 isoform X2. (195 aa)
THTyrosine hydroxylase. (596 aa)
KCNAB2Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (415 aa)
A0A287AT02_PIGUncharacterized protein. (116 aa)
KCNQ2Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family. (949 aa)
NFASCNeurofascin. (1587 aa)
AAK1AP2-associated protein kinase 1; Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2) which ensures high affinity binding of AP-2 to cargo membrane proteins during the initial stages of endocytosis. Regulates phosphorylation of other AP-2 subunits as well as AP-2 localization and AP-2-mediated internalization of ligand complexes. Phosphorylates NUMB and regulates its cellular localization, promoting NUMB localization to endosomes. Binds to and stabilizes the activated form of NOTCH1, increases its localization in endos [...] (1316 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (392 aa)
TSPOAP1TSPO associated protein 1. (1855 aa)
LGALS4Galectin-4; Galectin that binds lactose and a related range of sugars. May be involved in the assembly of adherens junctions. (321 aa)
MGPMatrix Gla protein; Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation. (127 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
Server load: low (36%) [HD]