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| | PABPC1L | Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (610 aa) |
| | HENMT1 | HEN methyltransferase 1. (383 aa) |
| | MEX3A | Mex-3 RNA binding family member A. (519 aa) |
| | ZC3H12D | Zinc finger CCCH-type containing 12D. (507 aa) |
| | RC3H2 | Ring finger and CCCH-type domains 2. (1192 aa) |
| | PNRC2 | Uncharacterized protein. (177 aa) |
| | TNRC6B | Trinucleotide repeat containing adaptor 6B. (1868 aa) |
| | PABPC4 | Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (660 aa) |
| | AGO2 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (874 aa) |
| | ROCK2 | Rho-associated protein kinase 2; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Positively regulates the activation of p42/MAPK1- p44/MAPK3 and of p90RSK/RPS6K [...] (1397 aa) |
| | RBPMS | RNA binding protein, mRNA processing factor. (223 aa) |
| | AJUBA | Ajuba LIM protein. (565 aa) |
| | MAEL | Protein maelstrom homolog; Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic n [...] (477 aa) |
| | LOC100738935 | Uncharacterized protein. (415 aa) |
| | LARP4B | HTH La-type RNA-binding domain-containing protein. (1587 aa) |
| | A0A5G2QHJ7_PIG | Uncharacterized protein. (148 aa) |
| | DDX4 | Probable ATP-dependent RNA helicase DDX4; ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycl [...] (744 aa) |
| | YTHDF2 | YTH N6-methyladenosine RNA binding protein 2. (600 aa) |
| | UHMK1 | Serine/threonine-protein kinase Kist isoform 1. (419 aa) |
| | XRN1 | 5'-3' exoribonuclease 1. (1703 aa) |
| | LSM14A | Uncharacterized protein. (475 aa) |
| | RBFOX1 | RNA binding fox-1 homolog 1. (577 aa) |
| | POLDIP3 | Polymerase delta-interacting protein 3 isoform X1. (420 aa) |
| | A0A5G2QZE0_PIG | Uncharacterized protein. (239 aa) |
| | MOV10L1 | AAA_12 domain-containing protein. (119 aa) |
| | LGALSL | Galectin. (183 aa) |
| | FASTKD5 | FAST kinase domains 5. (813 aa) |
| | SUMO1 | Small ubiquitin-related modifier 1. (141 aa) |
| | MCRIP1 | MAPK regulated corepressor interacting protein 1. (123 aa) |
| | TDRKH | Tudor and KH domain containing. (611 aa) |
| | LOC100737265 | Small ubiquitin-related modifier 1; Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post- translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for insta [...] (101 aa) |
| | HNRNPL | Heterogeneous nuclear ribonucleoprotein L. (454 aa) |
| | ATXN2L | Ataxin 2 like. (1080 aa) |
| | MBNL1 | Muscleblind like splicing regulator 1. (436 aa) |
| | OGFOD1 | 2-oxoglutarate and iron dependent oxygenase domain containing 1. (560 aa) |
| | RC3H1 | Ring finger and CCCH-type domains 1. (1132 aa) |
| | PUM1 | Pumilio RNA binding family member 1. (1189 aa) |
| | CT55 | S1-like domain-containing protein. (254 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit 1; Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre- initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF- 2 must exchange with GTP by way of a reaction catalyzed [...] (315 aa) |
| | EIF4ENIF1 | Eukaryotic translation initiation factor 4E nuclear import factor 1. (984 aa) |
| | VCP | Transitional endoplasmic reticulum ATPase; Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic reticulum (tER). Vesicle budding from the tER is an ATP-dependent process. The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is neces [...] (878 aa) |
| | G3BP1 | G3BP stress granule assembly factor 1. (495 aa) |
| | HSF1 | Heat shock transcription factor 1. (590 aa) |
| | TIAL1 | TIA1 cytotoxic granule associated RNA binding protein like 1. (395 aa) |
| | C8orf88 | Chromosome 8 open reading frame 88. (122 aa) |
| | PPP1R27 | Protein phosphatase 1 regulatory subunit 27. (154 aa) |
| | ATXN2 | Ataxin 2. (1335 aa) |
| | YTHDF1 | YTH N6-methyladenosine RNA binding protein 1. (652 aa) |
| | FMR1 | Fragile X mental retardation protein 1. (632 aa) |
| | IGF2BP2 | Insulin like growth factor 2 mRNA binding protein 2. (592 aa) |
| | PABPC1 | Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (636 aa) |
| | TIA1 | TIA1 cytotoxic granule associated RNA binding protein. (386 aa) |
| | DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 tv1. (1012 aa) |
| | TDRD1 | Tudor domain containing 1. (1177 aa) |
| | DCP1A | mRNA-decapping enzyme 1A; Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1; Belongs to the DCP1 family. (580 aa) |
| | TOP1 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (769 aa) |
| | ZFP36 | Uncharacterized protein. (372 aa) |
| | PIWIL2 | Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family. (985 aa) |
| | DDX28 | DEAD-box helicase 28. (540 aa) |
| | ZFAND1 | AN1-type zinc finger protein 1 isoform a. (268 aa) |
| | TDRD6 | Tudor domain containing 6. (2113 aa) |
| | FXR2 | FMR1 autosomal homolog 2. (667 aa) |
| | RNF135 | E3 ubiquitin-protein ligase RNF135 isoform 1. (423 aa) |
| | GRB7 | Growth factor receptor bound protein 7. (569 aa) |
| | ENDOV | Endonuclease V. (250 aa) |
| | LARP1 | La ribonucleoprotein domain family member 1. (1101 aa) |
| | ASZ1 | Ankyrin repeat, SAM and basic leucine zipper domain containing 1. (477 aa) |
| | FASTKD2 | FAST kinase domain-containing protein 2, mitochondrial. (689 aa) |
| | HOXD10 | Homeobox protein Hox-D10. (410 aa) |
| | F1SF34_PIG | RRM domain-containing protein. (170 aa) |
| | UBAP2 | Ubiquitin associated protein 2. (1133 aa) |
| | DHX30 | DExH-box helicase 30. (1194 aa) |
| | ZCCHC13 | Zinc finger CCHC-type containing 13. (171 aa) |
| | KIAA0355 | KIAA0355. (1074 aa) |
| | PIWIL4 | Piwi like RNA-mediated gene silencing 4; Belongs to the argonaute family. (906 aa) |
| | TNRC6C | Trinucleotide repeat containing adaptor 6C. (1932 aa) |
| | TNRC6A | Trinucleotide repeat containing adaptor 6A. (1989 aa) |
| | PNRC1 | Proline rich nuclear receptor coactivator 1. (327 aa) |
| | LARP1B | La ribonucleoprotein domain family member 1B. (1116 aa) |
| | EDC3 | Enhancer of mRNA decapping 3. (508 aa) |
| | TUT4 | Terminal uridylyl transferase 4. (1669 aa) |
| | NANOS2 | Nanos C2HC-type zinc finger 2; Belongs to the nanos family. (138 aa) |
| | BTBD1 | BTB/POZ domain-containing protein 1 isoform 1. (484 aa) |
| | EDC4 | Enhancer of mRNA decapping 4. (1402 aa) |
| | TDRD9 | Tudor domain containing 9. (1389 aa) |
| | NRDE2 | NRDE-2, necessary for RNA interference, domain containing. (1166 aa) |
| | CARHSP1 | Calcium regulated heat stable protein 1. (146 aa) |
| | PABPC4L | Poly(A) binding protein cytoplasmic 4 like. (341 aa) |
| | DIS3L2 | DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (914 aa) |
| | CAPRIN1 | Cell cycle associated protein 1. (709 aa) |
| | AGO4 | Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (878 aa) |
| | G3BP2 | Ras GTPase-activating protein-binding protein 2 isoform X1. (481 aa) |
| | ZC3H12A | Zinc finger CCCH-type containing 12A. (582 aa) |
| | TDRD10 | RRM domain-containing protein. (387 aa) |
| | MEX3B | Mex-3 RNA binding family member B. (576 aa) |
| | CELF1 | CUGBP Elav-like family member 1. (551 aa) |
| | SMG1 | SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3646 aa) |
| | MOV10 | Mov10 RISC complex RNA helicase. (1093 aa) |
| | TRUB2 | Mitochondrial mRNA pseudouridine synthase TRUB2 isoform 1. (349 aa) |
| | SHFL | Uncharacterized protein. (286 aa) |
| | TRIM71 | E3 ubiquitin-protein ligase TRIM71. (869 aa) |
| | ARC | Activity regulated cytoskeleton associated protein. (396 aa) |
| | YTHDC2 | YTH domain containing 2. (1430 aa) |
| | YTHDF3 | YTH domain-containing family protein 3 isoform b. (588 aa) |
| | ZC3H12C | Putative ribonuclease ZC3H12C isoform X1. (885 aa) |
| | PATL1 | PAT1 homolog 1, processing body mRNA decay factor. (786 aa) |
| | DDX6 | Putative ATP-dependent RNA helicase DDX6 isoform X1; Belongs to the DEAD box helicase family. (483 aa) |
| | HABP4 | Intracellular hyaluronan-binding protein 4. (418 aa) |
| | MIEF1 | Mitochondrial dynamics protein MID51 isoform X1. (463 aa) |
| | TDRD5 | Tudor domain containing 5. (974 aa) |
| | RPUSD4 | RNA pseudouridylate synthase domain-containing protein 4. (376 aa) |
| | DDX25 | ATP-dependent RNA helicase DDX25 isoform 1. (483 aa) |
| | DCP2 | Decapping mRNA 2. (478 aa) |
| | NANOS3 | Nanos C2HC-type zinc finger 3; Belongs to the nanos family. (261 aa) |
| | ELAVL1 | ELAV-like protein; Belongs to the RRM elav family. (326 aa) |
| | BTBD2 | BTB/POZ domain-containing protein 2. (515 aa) |
| | ZC3H12B | Zinc finger CCCH-type containing 12B. (836 aa) |
| | DDX3X | ATP-dependent RNA helicase DDX3X isoform 1; Belongs to the DEAD box helicase family. (662 aa) |
| | RPUSD3 | Mitochondrial mRNA pseudouridine synthase RPUSD3 isoform 1. (352 aa) |
| | LIMD1 | LIM domain-containing protein 1. (671 aa) |
| | PIWIL1 | Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family. (861 aa) |
| | GRSF1 | G-rich RNA sequence binding factor 1. (621 aa) |
| | MCRIP2 | MAPK regulated corepressor interacting protein 2. (156 aa) |
