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| | ITGAM | Integrin subunit alpha M; Belongs to the integrin alpha chain family. (1272 aa) |
| | TFR2 | Transferrin receptor 2. (804 aa) |
| | LOC100515824 | Insulin receptor substrate 1-like isoform X2. (512 aa) |
| | SDCBP2 | Syndecan binding protein 2. (291 aa) |
| | SCP2D1 | SCP2 sterol binding domain containing 1. (219 aa) |
| | VCAM1 | Uncharacterized protein. (537 aa) |
| | AMY2 | Pancreatic alpha-amylase. (511 aa) |
| | ARNT | Aryl hydrocarbon receptor nuclear translocator isoform X3. (790 aa) |
| | NPR1 | Guanylate cyclase. (1057 aa) |
| | BGLAP | Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. (100 aa) |
| | INSRR | Tyrosine-protein kinase receptor. (1315 aa) |
| | LYN | Tyrosine-protein kinase. (512 aa) |
| | LY96 | Lymphocyte antigen 96 isoform 1. (160 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (520 aa) |
| | ANGPTL2 | Angiopoietin-related protein 2. (493 aa) |
| | COL27A1 | Collagen type XXVII alpha 1 chain. (1843 aa) |
| | FAM189A2 | Family with sequence similarity 189 member A2. (601 aa) |
| | FAM189A1 | Family with sequence similarity 189 member A1. (538 aa) |
| | GABRA5 | Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (463 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1367 aa) |
| | SPPL2A | Signal peptide peptidase like 2A. (694 aa) |
| | GRIK2 | Glutamate ionotropic receptor kainate type subunit 2. (908 aa) |
| | LOC100520342 | Nephrocan-like. (512 aa) |
| | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa) |
| | ROR1 | Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa) |
| | NIPAL3 | NIPA like domain containing 3. (406 aa) |
| | AADACL3 | Arylacetamide deacetylase like 3. (409 aa) |
| | AADACL4 | Arylacetamide deacetylase like 4. (407 aa) |
| | TAS1R1 | Taste 1 receptor member 1. (844 aa) |
| | TAS1R3 | G_PROTEIN_RECEP_F3_4 domain-containing protein. (855 aa) |
| | CACNG8 | Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (423 aa) |
| | GRIN2D | Glutamate ionotropic receptor NMDA type subunit 2D. (1332 aa) |
| | GRIK5 | Glutamate ionotropic receptor kainate type subunit 5. (980 aa) |
| | F1S6S4_PIG | Ig-like domain-containing protein. (144 aa) |
| | SSTR1 | Somatostatin receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa) |
| | CYP1A1 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (538 aa) |
| | TSPAN32 | Tetraspanin 32; Belongs to the tetraspanin (TM4SF) family. (239 aa) |
| | ITGB2 | Integrin beta-2; Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor [...] (903 aa) |
| | INS | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (108 aa) |
| | AHRR | Uncharacterized protein. (695 aa) |
| | GRIA2 | Glutamate ionotropic receptor AMPA type subunit 2. (883 aa) |
| | SOST | Sclerostin. (212 aa) |
| | RAMP3 | Receptor activity-modifying protein 3; Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner. Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) and GPER1 to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL (By similarity). (151 aa) |
| | CHRNA5 | Cholinergic receptor nicotinic alpha 5 subunit. (475 aa) |
| | A0A287ARF7_PIG | Ig-like domain-containing protein. (139 aa) |
| | GPR156 | G protein-coupled receptor 156. (813 aa) |
| | GRIK3 | Glutamate ionotropic receptor kainate type subunit 3. (999 aa) |
| | POLN | DNA polymerase nu. (900 aa) |
| | LRRTM4 | Leucine rich repeat transmembrane neuronal 4. (590 aa) |
| | PTCRA | Uncharacterized protein. (245 aa) |
| | VWF | Von Willebrand factor; Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet- surface receptor complex, glycoprotein Ibalpha/IX/V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma (By similarity). (2940 aa) |
| | CD27 | CD27. (249 aa) |
| | OLR1 | Oxidized low-density lipoprotein receptor 1, soluble form; Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses includin [...] (272 aa) |
| | ITGA5 | Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1057 aa) |
| | TNS2 | Tensin 2. (1350 aa) |
| | ACVRL1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa) |
| | CSF2RB | Colony stimulating factor 2 receptor beta common subunit. (893 aa) |
| | ZNF131 | Zinc finger protein 131. (589 aa) |
| | CACNG4 | Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (326 aa) |
| | ITGAE | Integrin subunit alpha E; Belongs to the integrin alpha chain family. (1168 aa) |
| | ARNTL2 | Aryl hydrocarbon receptor nuclear translocator like 2. (652 aa) |
| | GRIN2B | Glutamate ionotropic receptor NMDA type subunit 2B. (1484 aa) |
| | ARNT2 | Aryl hydrocarbon receptor nuclear translocator 2. (892 aa) |
| | LOC110257903 | Fibronectin type-III domain-containing protein. (388 aa) |
| | HTR2A | 5-hydroxytryptamine receptor 2A; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5- dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. S [...] (470 aa) |
| | SYK | 40 kDa tyrosine-protein kinase SYK; Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the recepto [...] (628 aa) |
| | SSTR5 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (305 aa) |
| | LRP8 | LDL receptor related protein 8. (998 aa) |
| | GRIA1 | Glutamate ionotropic receptor AMPA type subunit 1. (906 aa) |
| | AASDH | Aminoadipate-semialdehyde dehydrogenase. (1076 aa) |
| | ITGA7 | Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1169 aa) |
| | CCR9 | Chemokine (C-C motif) receptor 9 isoform A; Belongs to the G-protein coupled receptor 1 family. (369 aa) |
| | MADCAM1 | Mucosal addressin cell adhesion molecule 1 isoform a. (390 aa) |
| | GRM1 | Glutamate metabotropic receptor 1. (1195 aa) |
| | ITGB8 | Integrin beta; Belongs to the integrin beta chain family. (722 aa) |
| | CACNG3 | Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa) |
| | A0A287AXM5_PIG | PA14 domain-containing protein. (723 aa) |
| | LRP2 | Low-density lipoprotein receptor-related protein 2; Multiligand endocytic receptor (By similarity). Acts together with CUBN to mediate endocytosis of high-density lipoproteins (By similarity). Mediates receptor-mediated uptake of polybasic drugs such as aprotinin, aminoglycosides and polymyxin B (By similarity). In the kidney, mediates the tubular uptake and clearance of leptin (By similarity). Also mediates transport of leptin across the blood-brain barrier through endocytosis at the choroid plexus epithelium (By similarity). Endocytosis of leptin in neuronal cells is required for hyp [...] (4626 aa) |
| | ITGB5 | Integrin beta; Belongs to the integrin beta chain family. (800 aa) |
| | PRF1 | Perforin 1. (555 aa) |
| | GRIN1 | Glutamate ionotropic receptor NMDA type subunit 1. (959 aa) |
| | NOTCH1 | Neurogenic locus notch homolog protein 1 preproprotein. (2560 aa) |
| | GPBAR1 | G protein-coupled bile acid receptor 1. (329 aa) |
| | A0A287A3M1_PIG | Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (398 aa) |
| | CYP4F2 | Phylloquinone omega-hydroxylase CYP4F2; Belongs to the cytochrome P450 family. (524 aa) |
| | ARNTL | Aryl hydrocarbon receptor nuclear translocator like. (633 aa) |
| | ITGA11 | Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1282 aa) |
| | CD40 | Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity). (278 aa) |
| | IRS2 | Insulin receptor substrate 2. (1092 aa) |
| | PTPRA | Protein tyrosine phosphatase receptor type A. (850 aa) |
| | CNIH3 | Cornichon family AMPA receptor auxiliary protein 3. (195 aa) |
| | NIPAL2 | NIPA like domain containing 2. (402 aa) |
| | CSF2RA | Fibronectin type-III domain-containing protein. (446 aa) |
| | CHRNB2 | Cholinergic receptor nicotinic beta 2 subunit. (502 aa) |
| | VDR | Vitamin D3 receptor; Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells (By similarity). Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR (By similarity). The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes (By similarity). Plays a central role in calcium homeostasis (By similarity). (520 aa) |
| | IL1RL1 | Interleukin 1 receptor like 1. (573 aa) |
| | ACVR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (729 aa) |
| | CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa) |
| | CHRNB1 | Cholinergic receptor nicotinic beta 1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (563 aa) |
| | GABRB3 | Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (513 aa) |
| | IL10RA | Interleukin 10 receptor subunit alpha. (576 aa) |
| | CD3E | T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...] (267 aa) |
| | GRIK4 | Glutamate ionotropic receptor kainate type subunit 4. (956 aa) |
| | SEMA3E | Semaphorin-3E isoform 1; Belongs to the semaphorin family. (775 aa) |
| | NSL1 | NSL1 component of MIS12 kinetochore complex. (290 aa) |
| | IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (219 aa) |
| | ACVR1C | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (500 aa) |
| | FN1 | Fibronectin 1. (2462 aa) |
| | HTR2B | 5-hydroxytryptamine receptor 2B; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide- binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity [...] (481 aa) |
| | RAMP1 | Receptor activity-modifying protein 1; Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for calcitonin-gene-related peptide (CGRP) together with CALCRL (By similarity). (271 aa) |
| | F6Q8R7_PIG | Ig-like domain-containing protein. (311 aa) |
| | OSMR | Oncostatin-M-specific receptor subunit beta isoform X1. (977 aa) |
| | ITGA2 | Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1178 aa) |
| | GABRG2 | Gamma-aminobutyric acid receptor subunit gamma-2 isoform 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (475 aa) |
| | GABRA1 | Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (518 aa) |
| | SSTR2 | Somatostatin receptor type 2; Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 [...] (360 aa) |
| | CD79B | CD79b molecule. (228 aa) |
| | RAMP2 | Receptor activity-modifying protein 2. (177 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1255 aa) |
| | GP1BA | Platelet glycoprotein Ib alpha polypeptide. (627 aa) |
| | CD4 | CD4 molecule. (494 aa) |
| | IL9 | Uncharacterized protein. (141 aa) |
| | ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1342 aa) |
| | GRIA4 | Glutamate ionotropic receptor AMPA type subunit 4. (884 aa) |
| | CSF2 | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. (144 aa) |
| | PLXNA2 | Plexin A2. (1937 aa) |
| | FSHR | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa) |
| | TLR6 | Toll-like receptor 6; Belongs to the Toll-like receptor family. (796 aa) |
| | GPSM2 | G-protein-signaling modulator 2 isoform X1. (680 aa) |
| | NOTCH3 | Notch receptor 3. (2321 aa) |
| | IL1RL2 | Interleukin 1 receptor like 2. (644 aa) |
| | GABRA3 | Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (506 aa) |
| | LRP1B | LDL receptor related protein 1B. (4586 aa) |
| | CACNG7 | Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa) |
| | AP1M2 | AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (497 aa) |
| | CYP4F8 | Cytochrome P450 family 4 subfamily F member 8; Belongs to the cytochrome P450 family. (678 aa) |
| | AHR | Aryl hydrocarbon receptor. (849 aa) |
| | LOC102163598 | 5-hydroxytryptamine receptor 3C; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (448 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (241 aa) |
| | BMPR1B | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | GABRA4 | Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (554 aa) |
| | TRAT1 | T cell receptor associated transmembrane adaptor 1. (181 aa) |
| | TLR1 | Toll-like receptor 1; Belongs to the Toll-like receptor family. (796 aa) |
| | F1S985_PIG | Ig-like domain-containing protein. (125 aa) |
| | GABRR2 | Gamma-aminobutyric acid type A receptor rho2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (465 aa) |
| | NLRP13 | NLR family pyrin domain containing 13. (983 aa) |
| | CHRNB3 | Cholinergic receptor nicotinic beta 3 subunit. (459 aa) |
| | IL15RA | Sushi domain-containing protein. (305 aa) |
| | GRIN3B | Glutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1031 aa) |
| | GRIN2C | Glutamate ionotropic receptor NMDA type subunit 2C. (872 aa) |
| | GPR20 | G protein-coupled receptor 20; Belongs to the G-protein coupled receptor 1 family. (352 aa) |
| | CHRNA9 | Cholinergic receptor nicotinic alpha 9 subunit. (479 aa) |
| | GRIK1 | Glutamate ionotropic receptor kainate type subunit 1. (949 aa) |
| | GP6 | Ig-like domain-containing protein. (319 aa) |
| | HTR3A | 5-hydroxytryptamine receptor 3A isoform c; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (483 aa) |
| | PLXNA3 | Plexin A3. (1871 aa) |
| | ITGA3 | Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1085 aa) |
| | IL7R | Fibronectin type-III domain-containing protein. (458 aa) |
| | GP1BB | Platelet glycoprotein Ib beta chain. (203 aa) |
| | CD3D | T-cell surface glycoprotein CD3 delta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of [...] (171 aa) |
| | LIFR | LIF receptor subunit alpha. (1170 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa) |
| | IL27RA | Uncharacterized protein. (683 aa) |
| | NR3C2 | Mineralocorticoid receptor; Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels (By similarity). (984 aa) |
| | GRIA3 | Glutamate ionotropic receptor AMPA type subunit 3. (894 aa) |
| | IL13 | Interleukin-13; Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macrophages. (131 aa) |
| | TNFRSF9 | TNF receptor superfamily member 9. (260 aa) |
| | GABRQ | Gamma-aminobutyric acid receptor subunit theta isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (697 aa) |
| | CD6 | CD6 molecule. (671 aa) |
| | ZAP70 | Tyrosine-protein kinase. (615 aa) |
| | IL18R1 | Interleukin 18 receptor 1. (539 aa) |
| | GRIN2A | Glutamate ionotropic receptor NMDA type subunit 2A. (1464 aa) |
| | CYP4F3 | Cytochrome P450 family 4 subfamily F member 3; Belongs to the cytochrome P450 family. (524 aa) |
| | TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein. (304 aa) |
| | GABRG3 | Gamma-aminobutyric acid type A receptor gamma3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (467 aa) |
| | GRIN3A | Glutamate ionotropic receptor NMDA type subunit 3A. (1114 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. (154 aa) |
| | GNAT1 | Guanine nucleotide-binding protein G(T) subunit alpha-1 isoform X2. (350 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa) |
| | IL20RA | Interleukin 20 receptor subunit alpha. (689 aa) |
| | CD79A | Ig-like domain-containing protein. (234 aa) |
| | IFNLR1 | Interferon lambda receptor 1. (519 aa) |
| | SDCBP | Syndecan binding protein. (300 aa) |
| | LOC102167481 | Uncharacterized protein; Belongs to the cytochrome P450 family. (524 aa) |
| | GABRA2 | Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (511 aa) |
| | ACVR1B | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (547 aa) |
| | A0A5G2RFF3_PIG | Ig-like domain-containing protein. (83 aa) |
| | SSTR3 | Somatostatin receptor 3; Belongs to the G-protein coupled receptor 1 family. (421 aa) |
| | LOC100524773 | Uncharacterized protein. (2024 aa) |
| | ITGA10 | Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1352 aa) |
| | ITGA4 | Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1055 aa) |
| | CHRNA10 | Cholinergic receptor nicotinic alpha 10 subunit. (450 aa) |
| | A0A287AB18_PIG | Uncharacterized protein. (385 aa) |
| | RASD2 | RASD family member 2. (303 aa) |
| | BMPR1A | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | CALCRL | Calcitonin gene-related peptide type 1 receptor; Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity). (463 aa) |
| | TNFRSF4 | TNF receptor superfamily member 4. (278 aa) |
| | PLXNA1 | Plexin A1. (1909 aa) |
| | GABRR3 | Neur_chan_memb domain-containing protein. (187 aa) |
| | IL29 | Interferon lambda-1. (191 aa) |
| | GABRD | Gamma-aminobutyric acid type A receptor delta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (590 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (835 aa) |
| | BMP2 | Bone morphogenetic protein 2 preproprotein. (395 aa) |
| | HTR3B | 5-hydroxytryptamine receptor 3B; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (442 aa) |
| | CD14 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (373 aa) |
| | FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1362 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1382 aa) |
| | LINGO3 | Leucine rich repeat and Ig domain containing 3. (592 aa) |
| | CD44 | CD44 molecule (Indian blood group). (767 aa) |
| | LRP5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1614 aa) |
| | PLXNB3 | Plexin B3. (1894 aa) |
| | GPR119 | G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family. (335 aa) |
| | IL13RA1 | Uncharacterized protein. (421 aa) |
| | DLG3 | Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (849 aa) |
| | LOC100156142 | 5-hydroxytryptamine receptor 3D; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa) |
| | IL5RA | Interleukin 5 receptor subunit alpha. (420 aa) |
| | PLXNB1 | Plexin B1. (2133 aa) |
| | ITGA9 | Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1035 aa) |
| | ITGA8 | Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1062 aa) |
| | CNTFR | Ciliary neurotrophic factor receptor. (438 aa) |
| | LOXL4 | Lysyl oxidase like 4. (757 aa) |
| | RET | Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1111 aa) |
| | DIABLO | Uncharacterized protein. (237 aa) |
| | CHRNA2 | Cholinergic receptor nicotinic alpha 2 subunit. (502 aa) |
| | PLXNC1 | Plexin C1. (1612 aa) |
| | CACNG2 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa) |
| | ACVR2A | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa) |
| | IL23R | Interleukin 23 receptor. (631 aa) |
| | STAC2 | SH3 and cysteine rich domain 2. (529 aa) |
| | A0A5G2R3Y0_PIG | Ig-like domain-containing protein. (169 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1085 aa) |
| | GABBR1 | Gamma-aminobutyric acid type B receptor subunit 1. (1247 aa) |
| | RUNX2 | Runt-related transcription factor 2 isoform a. (625 aa) |
| | HTR1D | 5-hydroxytryptamine receptor 1D; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitte [...] (377 aa) |
| | PLXND1 | Plexin D1. (1926 aa) |
| | CHRNA7 | Uncharacterized protein. (585 aa) |
| | CCL25 | C-C motif chemokine 25; Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4 (By similarity); Belongs to the intercrine beta (chemokine CC) family. (220 aa) |
| | IL6R | Interleukin-6 receptor subunit alpha; Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis; Belongs to the type I cytokine receptor family. Type 3 subfamily. (491 aa) |
| | SPN | Uncharacterized protein. (463 aa) |
| | TPD52 | Uncharacterized protein. (247 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1205 aa) |
| | IL1R1 | Interleukin-1 receptor type 1 isoform 1. (572 aa) |
| | A0A5G2QS47_PIG | Ig-like domain-containing protein. (179 aa) |
| | ACVR2B | Activin receptor type-2B; Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1, ACVR1B or ACVR1c). Transduces the activin signal from the cell surface to the cytoplasm and is thus regulating many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to [...] (565 aa) |
| | ITGA1 | Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1175 aa) |
| | GABRB2 | Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa) |
| | ADAM28 | ADAM metallopeptidase domain 28. (795 aa) |
| | MCMDC2 | Minichromosome maintenance domain containing 2. (681 aa) |
| | NR1H4 | Nuclear receptor subfamily 1 group H member 4. (509 aa) |
| | IL-15L | Uncharacterized protein. (143 aa) |
| | FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1302 aa) |
| | AMHR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (583 aa) |
| | GABRE | Gamma-aminobutyric acid type A receptor epsilon subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (499 aa) |
| | VWC2L | Von Willebrand factor C domain-containing protein 2-like isoform 1. (222 aa) |
| | IL12RB1 | Interleukin 12 receptor subunit beta 1. (749 aa) |
| | IRS1 | Insulin receptor substrate 1. (1241 aa) |
| | GABBR2 | Gamma-aminobutyric acid type B receptor subunit 2. (958 aa) |
| | CD247 | T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...] (168 aa) |
| | ITGB1 | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] (853 aa) |
| | CD2 | T-cell surface antigen CD2 isoform 2. (370 aa) |
| | TGFBR1 | TGF-beta receptor type-1; Transmembrane serine/threonine kinase forming with the TGF- beta type II serine/threonine kinase receptor, TGFBR2, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinog [...] (560 aa) |
| | HTR2C | 5-hydroxytryptamine receptor 2C. (457 aa) |
| | ITGAV | Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1052 aa) |
| | ITGB6 | Integrin beta-6; Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity). It recognizes the sequence R-G-D in its ligands (By similarity). ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R- G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (By similarity). (854 aa) |
| | TRAV3 | T cell receptor alpha variable 3 (gene/pseudogene). (164 aa) |
| | GHR | Growth hormone-binding protein; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway. (660 aa) |
| | ITGB7 | Integrin beta; Belongs to the integrin beta chain family. (882 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (572 aa) |
| | GDNF | Glial cell line-derived neurotrophic factor isoform 1. (211 aa) |
| | CD3G | T-cell surface glycoprotein CD3 gamma chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of [...] (176 aa) |
| | CHRNA6 | Cholinergic receptor nicotinic alpha 6 subunit. (491 aa) |
| | TAS1R2 | Taste 1 receptor member 2. (836 aa) |
| | CD226 | CD226 antigen isoform a. (335 aa) |
| | GABRB1 | Gamma-aminobutyric acid type A receptor beta1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa) |
| | TLR4 | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (841 aa) |
| | ITGA6 | Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1072 aa) |
| | PLGRKT | Plasminogen receptor with a C-terminal lysine. (186 aa) |
| | PLXNA4 | Plexin-A4 isoform X1. (1893 aa) |
| | SH2D1B | SH2 domain-containing protein. (133 aa) |
| | IL6ST | Interleukin 6 signal transducer. (938 aa) |
| | TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (319 aa) |
| | GABRG1 | Gamma-aminobutyric acid type A receptor gamma1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (465 aa) |
| | FGFBP1 | Fibroblast growth factor-binding protein 1. (237 aa) |
| | IL1B2 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa) |
| | IL4R | Interleukin-4 receptor subunit alpha; Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2 (By similarity). (830 aa) |
| | ITGAL | Integrin subunit alpha L; Belongs to the integrin alpha chain family. (1235 aa) |
