(17 nodes) Laminin complex network (Sus scrofa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LAMB4	Uncharacterized protein. (719 aa)
	DAG1	Alpha-dystroglycan; The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sacrolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization. Beta-dystroglycan is a transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non- muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell ad [...] (912 aa)
	NTNG1	Netrin G1. (588 aa)
	PERCC1	Uncharacterized protein. (280 aa)
	LAMB1	Laminin subunit beta 1. (1785 aa)
	LAMA4	Laminin subunit alpha 4. (1815 aa)
	LAMA3	Laminin subunit alpha 3. (3345 aa)
	MESP1	Mesoderm posterior bHLH transcription factor 1. (256 aa)
	NTN4	Netrin 4. (628 aa)
	LAMB3	Laminin subunit beta 3. (1172 aa)
	FN1	Fibronectin 1. (2462 aa)
	FBN3	Fibrillin 3. (2858 aa)
	C11orf53	Chromosome 11 open reading frame 53. (285 aa)
	ITGA3	Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1085 aa)
	NTNG2	Netrin G2. (529 aa)
	COL8A2	Collagen type VIII alpha 2 chain. (707 aa)
	LAMB2	Laminin subunit beta-2. (1881 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DAG1	LAMA3	ENSSSCP00000053965	ENSSSCP00000004016	Alpha-dystroglycan; The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sacrolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization. Beta-dystroglycan is a transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non- muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell ad [...]	Laminin subunit alpha 3.	0.775
DAG1	LAMA4	ENSSSCP00000053965	ENSSSCP00000004775	Alpha-dystroglycan; The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sacrolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization. Beta-dystroglycan is a transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non- muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell ad [...]	Laminin subunit alpha 4.	0.743
DAG1	LAMB1	ENSSSCP00000053965	ENSSSCP00000016375	Alpha-dystroglycan; The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sacrolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization. Beta-dystroglycan is a transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non- muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell ad [...]	Laminin subunit beta 1.	0.725
DAG1	LAMB2	ENSSSCP00000053965	ENSSSCP00000048374	Alpha-dystroglycan; The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sacrolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization. Beta-dystroglycan is a transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non- muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell ad [...]	Laminin subunit beta-2.	0.720
DAG1	LAMB3	ENSSSCP00000053965	ENSSSCP00000016558	Alpha-dystroglycan; The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sacrolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization. Beta-dystroglycan is a transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non- muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell ad [...]	Laminin subunit beta 3.	0.690
DAG1	LAMB4	ENSSSCP00000053965	ENSSSCP00000051372	Alpha-dystroglycan; The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sacrolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization. Beta-dystroglycan is a transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non- muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell ad [...]	Uncharacterized protein.	0.650
FN1	ITGA3	ENSSSCP00000017132	ENSSSCP00000028475	Fibronectin 1.	Integrin subunit alpha 3; Belongs to the integrin alpha chain family.	0.959
ITGA3	FN1	ENSSSCP00000028475	ENSSSCP00000017132	Integrin subunit alpha 3; Belongs to the integrin alpha chain family.	Fibronectin 1.	0.959
ITGA3	LAMA3	ENSSSCP00000028475	ENSSSCP00000004016	Integrin subunit alpha 3; Belongs to the integrin alpha chain family.	Laminin subunit alpha 3.	0.864
ITGA3	LAMA4	ENSSSCP00000028475	ENSSSCP00000004775	Integrin subunit alpha 3; Belongs to the integrin alpha chain family.	Laminin subunit alpha 4.	0.862
ITGA3	LAMB1	ENSSSCP00000028475	ENSSSCP00000016375	Integrin subunit alpha 3; Belongs to the integrin alpha chain family.	Laminin subunit beta 1.	0.862
ITGA3	LAMB2	ENSSSCP00000028475	ENSSSCP00000048374	Integrin subunit alpha 3; Belongs to the integrin alpha chain family.	Laminin subunit beta-2.	0.761
ITGA3	LAMB3	ENSSSCP00000028475	ENSSSCP00000016558	Integrin subunit alpha 3; Belongs to the integrin alpha chain family.	Laminin subunit beta 3.	0.837
ITGA3	LAMB4	ENSSSCP00000028475	ENSSSCP00000051372	Integrin subunit alpha 3; Belongs to the integrin alpha chain family.	Uncharacterized protein.	0.665
LAMA3	DAG1	ENSSSCP00000004016	ENSSSCP00000053965	Laminin subunit alpha 3.	Alpha-dystroglycan; The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sacrolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization. Beta-dystroglycan is a transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non- muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell ad [...]	0.775
LAMA3	ITGA3	ENSSSCP00000004016	ENSSSCP00000028475	Laminin subunit alpha 3.	Integrin subunit alpha 3; Belongs to the integrin alpha chain family.	0.864
LAMA3	LAMA4	ENSSSCP00000004016	ENSSSCP00000004775	Laminin subunit alpha 3.	Laminin subunit alpha 4.	0.572
LAMA3	LAMB1	ENSSSCP00000004016	ENSSSCP00000016375	Laminin subunit alpha 3.	Laminin subunit beta 1.	0.904
LAMA3	LAMB2	ENSSSCP00000004016	ENSSSCP00000048374	Laminin subunit alpha 3.	Laminin subunit beta-2.	0.720
LAMA3	LAMB3	ENSSSCP00000004016	ENSSSCP00000016558	Laminin subunit alpha 3.	Laminin subunit beta 3.	0.873