7 items (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PDK2	Protein-serine/threonine kinase. (437 aa)
	ALKBH6	Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 isoform 2. (238 aa)
	PDHB	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (361 aa)
	PDK1	Protein-serine/threonine kinase. (454 aa)
	PDHX	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (498 aa)
	PDHA1	Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. (396 aa)
	DLAT	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (667 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DLAT	PDHA1	ENSSSCP00000070907	ENSSSCP00000029133	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.	0.999
DLAT	PDHB	ENSSSCP00000070907	ENSSSCP00000065067	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.999
DLAT	PDHX	ENSSSCP00000070907	ENSSSCP00000067070	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.985
DLAT	PDK1	ENSSSCP00000070907	ENSSSCP00000066226	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Protein-serine/threonine kinase.	0.781
DLAT	PDK2	ENSSSCP00000070907	ENSSSCP00000059052	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Protein-serine/threonine kinase.	0.903
PDHA1	DLAT	ENSSSCP00000029133	ENSSSCP00000070907	Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.999
PDHA1	PDHB	ENSSSCP00000029133	ENSSSCP00000065067	Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.999
PDHA1	PDHX	ENSSSCP00000029133	ENSSSCP00000067070	Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.999
PDHA1	PDK1	ENSSSCP00000029133	ENSSSCP00000066226	Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.	Protein-serine/threonine kinase.	0.961
PDHA1	PDK2	ENSSSCP00000029133	ENSSSCP00000059052	Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.	Protein-serine/threonine kinase.	0.739
PDHB	DLAT	ENSSSCP00000065067	ENSSSCP00000070907	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.999
PDHB	PDHA1	ENSSSCP00000065067	ENSSSCP00000029133	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.	0.999
PDHB	PDHX	ENSSSCP00000065067	ENSSSCP00000067070	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.999
PDHB	PDK1	ENSSSCP00000065067	ENSSSCP00000066226	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Protein-serine/threonine kinase.	0.954
PDHB	PDK2	ENSSSCP00000065067	ENSSSCP00000059052	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Protein-serine/threonine kinase.	0.902
PDHX	DLAT	ENSSSCP00000067070	ENSSSCP00000070907	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.985
PDHX	PDHA1	ENSSSCP00000067070	ENSSSCP00000029133	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.	0.999
PDHX	PDHB	ENSSSCP00000067070	ENSSSCP00000065067	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.999
PDHX	PDK1	ENSSSCP00000067070	ENSSSCP00000066226	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Protein-serine/threonine kinase.	0.735
PDHX	PDK2	ENSSSCP00000067070	ENSSSCP00000059052	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Protein-serine/threonine kinase.	0.858