22 items (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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Predicted Interactions

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Your Input:
	VDAC3	Voltage-dependent anion-selective channel protein 3; Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules; Belongs to the eukaryotic mitochondrial porin family. (284 aa)
	SLC25A31	Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (323 aa)
	SCARF2	Scavenger receptor class F member 2. (873 aa)
	PPIF	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (237 aa)
	ABTB2	Ankyrin repeat and BTB/POZ domain-containing protein 2. (1025 aa)
	C8A	Complement C8 alpha chain. (589 aa)
	CD55	Uncharacterized protein. (609 aa)
	CD59	CD59 glycoprotein; Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. (123 aa)
	LOC100519295	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
	MROH2B	Maestro heat like repeat family member 2B. (1585 aa)
	C6	Uncharacterized protein. (927 aa)
	MEGF10	Uncharacterized protein. (368 aa)
	A0A287BE79_PIG	PH domain-containing protein. (292 aa)
	VDAC1	Voltage-dependent anion-selective channel protein 1; Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition p [...] (302 aa)
	C8B	MACPF domain-containing protein. (648 aa)
	C7	Complement component C7; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor. Belongs to the complement C6/C7/C8/C9 family. (841 aa)
	C9	MACPF domain-containing protein. (575 aa)
	CYCS	Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	SLC25A4	Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
	TSPAN33	Tetraspanin. (310 aa)
	C8G	Complement C8 gamma chain. (257 aa)
	BTBD11	Ankyrin repeat and BTB/POZ domain-containing protein BTBD11 isoform a. (1108 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C6	C7	ENSSSCP00000070538	ENSSSCP00000017865	Uncharacterized protein.	Complement component C7; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor. Belongs to the complement C6/C7/C8/C9 family.	0.947
C6	C8A	ENSSSCP00000070538	ENSSSCP00000004152	Uncharacterized protein.	Complement C8 alpha chain.	0.827
C6	C8B	ENSSSCP00000070538	ENSSSCP00000047073	Uncharacterized protein.	MACPF domain-containing protein.	0.688
C6	C8G	ENSSSCP00000070538	ENSSSCP00000042850	Uncharacterized protein.	Complement C8 gamma chain.	0.851
C6	C9	ENSSSCP00000070538	ENSSSCP00000017860	Uncharacterized protein.	MACPF domain-containing protein.	0.967
C6	CD59	ENSSSCP00000070538	ENSSSCP00000025898	Uncharacterized protein.	CD59 glycoprotein; Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore.	0.511
C6	VDAC1	ENSSSCP00000070538	ENSSSCP00000047193	Uncharacterized protein.	Voltage-dependent anion-selective channel protein 1; Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition p [...]	0.542
C6	VDAC3	ENSSSCP00000070538	ENSSSCP00000007488	Uncharacterized protein.	Voltage-dependent anion-selective channel protein 3; Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules; Belongs to the eukaryotic mitochondrial porin family.	0.542
C7	C6	ENSSSCP00000017865	ENSSSCP00000070538	Complement component C7; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor. Belongs to the complement C6/C7/C8/C9 family.	Uncharacterized protein.	0.947
C7	C8A	ENSSSCP00000017865	ENSSSCP00000004152	Complement component C7; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor. Belongs to the complement C6/C7/C8/C9 family.	Complement C8 alpha chain.	0.959
C7	C8B	ENSSSCP00000017865	ENSSSCP00000047073	Complement component C7; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor. Belongs to the complement C6/C7/C8/C9 family.	MACPF domain-containing protein.	0.930
C7	C8G	ENSSSCP00000017865	ENSSSCP00000042850	Complement component C7; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor. Belongs to the complement C6/C7/C8/C9 family.	Complement C8 gamma chain.	0.903
C7	C9	ENSSSCP00000017865	ENSSSCP00000017860	Complement component C7; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor. Belongs to the complement C6/C7/C8/C9 family.	MACPF domain-containing protein.	0.944
C7	CD59	ENSSSCP00000017865	ENSSSCP00000025898	Complement component C7; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor. Belongs to the complement C6/C7/C8/C9 family.	CD59 glycoprotein; Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore.	0.533
C7	VDAC1	ENSSSCP00000017865	ENSSSCP00000047193	Complement component C7; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor. Belongs to the complement C6/C7/C8/C9 family.	Voltage-dependent anion-selective channel protein 1; Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition p [...]	0.545
C7	VDAC3	ENSSSCP00000017865	ENSSSCP00000007488	Complement component C7; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor. Belongs to the complement C6/C7/C8/C9 family.	Voltage-dependent anion-selective channel protein 3; Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules; Belongs to the eukaryotic mitochondrial porin family.	0.547
C8A	C6	ENSSSCP00000004152	ENSSSCP00000070538	Complement C8 alpha chain.	Uncharacterized protein.	0.827
C8A	C7	ENSSSCP00000004152	ENSSSCP00000017865	Complement C8 alpha chain.	Complement component C7; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor. Belongs to the complement C6/C7/C8/C9 family.	0.959
C8A	C8B	ENSSSCP00000004152	ENSSSCP00000047073	Complement C8 alpha chain.	MACPF domain-containing protein.	0.935
C8A	C8G	ENSSSCP00000004152	ENSSSCP00000042850	Complement C8 alpha chain.	Complement C8 gamma chain.	0.989