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| | SCNN1A | Amiloride-sensitive sodium channel subunit alpha isoform 2; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (650 aa) |
| | TMPRSS12 | Transmembrane serine protease 12; Belongs to the peptidase S1 family. (366 aa) |
| | SERPINB12 | Serpin family B member 12; Belongs to the serpin family. (425 aa) |
| | RIMBP2 | RIMS-binding protein 2 isoform X2. (1496 aa) |
| | SLC17A9 | Solute carrier family 17 member 9. (600 aa) |
| | ECRG4 | ECRG4 augurin precursor. (147 aa) |
| | TMED10 | Transmembrane emp24 domain-containing protein 10. (219 aa) |
| | PRKACA | cAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose- mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the [...] (357 aa) |
| | CLCN3 | Chloride channel protein. (866 aa) |
| | KLK5 | Kallikrein related peptidase 5; Belongs to the peptidase S1 family. (295 aa) |
| | RAB5A | Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] (215 aa) |
| | SYN3 | Synapsin III. (580 aa) |
| | CXADR | Uncharacterized protein. (419 aa) |
| | SPX | Spexin hormone. (118 aa) |
| | CHGB | Secretogranin-1; Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides. (666 aa) |
| | VPS13B | Vacuolar protein sorting-associated protein 13B isoform X1. (4018 aa) |
| | STON2 | Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family. (955 aa) |
| | A0A286ZQA4_PIG | Uncharacterized protein. (275 aa) |
| | SYNPR | Synaptoporin. (288 aa) |
| | CACFD1 | Calcium channel flower domain containing 1. (172 aa) |
| | MT3 | Metallothionein-3; Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro (By similarity); Belongs to the metallothionein superfamily. Type 1 family. (95 aa) |
| | RAB12 | RAB12, member RAS oncogene family. (332 aa) |
| | PTPRN2 | Protein tyrosine phosphatase receptor type N2. (1032 aa) |
| | PPFIA3 | PTPRF interacting protein alpha 3. (1235 aa) |
| | LHFPL2 | LHFPL tetraspan subfamily member 2 protein isoform X1. (228 aa) |
| | SLC17A8 | Solute carrier family 17 member 8. (544 aa) |
| | SNCA | Alpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] (142 aa) |
| | MPO | Myeloperoxidase. (731 aa) |
| | CFB | Complement factor B; Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase; Belongs to the peptidase S1 family. (851 aa) |
| | SYN1 | Synapsin-1 isoform Ia. (712 aa) |
| | PRRT1 | Uncharacterized protein. (305 aa) |
| | CRISP3 | Cysteine rich secretory protein 3; Belongs to the CRISP family. (245 aa) |
| | CATSPER4 | Cation channel sperm associated 4. (471 aa) |
| | SLC30A3 | Uncharacterized protein. (464 aa) |
| | LTF | Lactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity. Shows a preferential cleavage at -Arg-Ser-Arg-Arg-|- and -Arg-Arg-Ser-Arg-|-, and of Z-Phe-Arg-|-aminomethylcoumarin sites. (704 aa) |
| | SYT5 | Synaptotagmin 5. (385 aa) |
| | F1RSX1_PIG | Uncharacterized protein. (200 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2702 aa) |
| | CATSPER3 | Ion_trans domain-containing protein. (425 aa) |
| | GCA | Grancalcin. (297 aa) |
| | SCFD2 | Sec1 family domain containing 2; Belongs to the STXBP/unc-18/SEC1 family. (684 aa) |
| | C6orf120 | Chromosome 6 open reading frame 120. (184 aa) |
| | PRSS57 | Serine protease 57; Belongs to the peptidase S1 family. (279 aa) |
| | SPATA1 | Spermatogenesis associated 1. (459 aa) |
| | POMC | Corticotropin-like intermediary peptide; [Corticotropin]: Stimulates the adrenal glands to release cortisol. [Melanocyte-stimulating hormone beta]: Increases the pigmentation of skin by increasing melanin production in melanocytes. [Met-enkephalin]: Endogenous opiate; Belongs to the POMC family. (381 aa) |
| | SPACA4 | Sperm acrosome associated 4. (126 aa) |
| | STX1B | Syntaxin 1B; Belongs to the syntaxin family. (288 aa) |
| | STX12 | t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (369 aa) |
| | VAMP8 | V-SNARE coiled-coil homology domain-containing protein. (143 aa) |
| | IQCF5 | IQ motif containing F5. (149 aa) |
| | DISC1 | DISC1 scaffold protein. (819 aa) |
| | ANXA7 | Annexin. (485 aa) |
| | PCSK1N | Proprotein convertase subtilisin/kexin type 1 inhibitor. (259 aa) |
| | PRSS37 | Putative inactive serine protease 37. (235 aa) |
| | SYT8 | Synaptotagmin 8. (381 aa) |
| | AMPH | Uncharacterized protein. (678 aa) |
| | SYNJ2 | Synaptojanin 2. (1402 aa) |
| | IQCF1 | IQ motif containing F1. (207 aa) |
| | SYCN | Syncollin. (136 aa) |
| | FSTL5 | Follistatin like 5. (856 aa) |
| | TMEM95 | Transmembrane protein 95. (184 aa) |
| | SLC2A4 | Solute carrier family 2, facilitated glucose transporter member 4; Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation. Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracellularly within storage compartments in muscle and fat cells. Upon insulin stimulation, translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu into the cell. (509 aa) |
| | SPACA3 | Uncharacterized protein; Belongs to the glycosyl hydrolase 22 family. (163 aa) |
| | EPX | Eosinophil peroxidase heavy chain; Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils; Belongs to the peroxidase family. XPO subfamily. (705 aa) |
| | LYZL6 | Lysozyme like 6; Belongs to the glycosyl hydrolase 22 family. (148 aa) |
| | UNC13D | Unc-13 homolog D. (1090 aa) |
| | STK31 | Serine/threonine kinase 31. (983 aa) |
| | IQUB | IQ motif and ubiquitin domain containing. (800 aa) |
| | SPAM1 | Hyaluronidase. (493 aa) |
| | CCDC136 | Coiled-coil domain containing 136. (1160 aa) |
| | LRGUK | Leucine rich repeats and guanylate kinase domain containing. (815 aa) |
| | GTPBP2 | GTP binding protein 2. (694 aa) |
| | PTPRN | Protein tyrosine phosphatase receptor type N. (978 aa) |
| | TMEM163 | Transmembrane protein 163. (287 aa) |
| | ZPBP | Zona pellucida-binding protein 1; Plays a role in acrosome compaction and sperm morphogenesis. Is implicated in sperm-oocyte interaction during fertilization. Belongs to the zona pellucida-binding protein Sp38 family. (350 aa) |
| | F1S342_PIG | Uncharacterized protein. (332 aa) |
| | KIRREL3 | Kirre like nephrin family adhesion molecule 3. (794 aa) |
| | ACRV1 | Acrosomal vesicle protein 1. (272 aa) |
| | TMEM225 | Uncharacterized protein. (233 aa) |
| | SYT9 | Synaptotagmin-9. (491 aa) |
| | PCYOX1L | Prenylcysteine oxidase 1 like. (457 aa) |
| | FSTL4 | Follistatin like 4. (848 aa) |
| | PCSK1 | P/Homo B domain-containing protein; Belongs to the peptidase S8 family. (760 aa) |
| | CRHBP | Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa) |
| | HEXB | Beta-hexosaminidase subunit beta; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. (538 aa) |
| | LMAN2 | Lectin, mannose binding 2. (359 aa) |
| | C1orf35 | Multiple myeloma tumor-associated protein 2. (237 aa) |
| | RAB3A | Ras-related protein Rab-3A; Small GTP-binding protein that plays a central role in regulated exocytosis and secretion. Controls the recruitment, tethering and docking of secretory vesicles to the plasma membrane (By similarity). Upon stimulation, switches to its active GTP-bound form, cycles to vesicles and recruits effectors such as RIMS1, RIMS2, Rabphilin-3A/RPH3A, RPH3AL or SYTL4 to help the docking of vesicules onto the plasma membrane (By similarity). Upon GTP hydrolysis by GTPase-activating protein, dissociates from the vesicle membrane allowing the exocytosis to proceed (By simi [...] (254 aa) |
| | RAB8A | Uncharacterized protein. (242 aa) |
| | STX10 | Syntaxin 10; Belongs to the syntaxin family. (353 aa) |
| | CALR | Calreticulin; Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis; Belongs to the calreticulin family. (417 aa) |
| | RAB11B | Uncharacterized protein. (205 aa) |
| | PRTN3 | Proteinase 3; Belongs to the peptidase S1 family. (268 aa) |
| | AZU1 | Azurocidin; This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin; Belongs to the peptidase S1 family. Elastase subfamily. (246 aa) |
| | SLC17A6 | Solute carrier family 17 member 6. (582 aa) |
| | SYTL4 | Synaptotagmin like 4. (721 aa) |
| | CYLC1 | Cylicin 1. (650 aa) |
| | SYP | Synaptophysin. (319 aa) |
| | SPACA5 | Sperm acrosome associated 5; Belongs to the glycosyl hydrolase 22 family. (160 aa) |
| | LYZL4 | Lysozyme like 4; Belongs to the glycosyl hydrolase 22 family. (145 aa) |
| | CTSV | Cathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (By similarity). Belongs to the peptidase C1 family. (334 aa) |
| | SYT2 | Synaptotagmin 2. (417 aa) |
| | NHLRC2 | NHL repeat-containing protein 2. (725 aa) |
| | FAM170B | Family with sequence similarity 170 member B. (286 aa) |
| | PRSS55 | Serine protease 55; Belongs to the peptidase S1 family. (337 aa) |
| | F1RJP7_PIG | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (293 aa) |
| | SFTPC | Pulmonary surfactant-associated protein C; Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. (208 aa) |
| | OLFM4 | Olfactomedin 4. (488 aa) |
| | PLAC8 | Uncharacterized protein. (161 aa) |
| | F1S151_PIG | Uncharacterized protein. (59 aa) |
| | QPCT | Glutaminyl-peptide cyclotransferase. (361 aa) |
| | PPP4R3B | Serine/threonine-protein phosphatase 4 regulatory subunit 3B isoform 3. (820 aa) |
| | ANXA4 | Annexin A4; Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis; Belongs to the annexin family. (337 aa) |
| | ASTL | Metalloendopeptidase. (392 aa) |
| | GP2 | Pancreatic secretory granule membrane major glycoprotein GP2 isoform 1. (532 aa) |
| | F1RPC9_PIG | ABC transporter domain-containing protein. (586 aa) |
| | F1RPD0_PIG | Uncharacterized protein. (1631 aa) |
| | CCDC189 | Coiled-coil domain-containing protein 189 isoform X1. (336 aa) |
| | STX1A | Syntaxin 1A; Belongs to the syntaxin family. (295 aa) |
| | SLC32A1 | Vesicular inhibitory amino acid transporter. (526 aa) |
| | STXBP3 | Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (940 aa) |
| | SLC6A17 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (727 aa) |
| | CD58 | Uncharacterized protein. (243 aa) |
| | ADAM30 | ADAM metallopeptidase domain 30. (727 aa) |
| | SV2A | Synaptic vesicle glycoprotein 2A isoform 1. (742 aa) |
| | F5 | Coagulation factor V heavy chain; Coagulation factor V is a cofactor that participates with factor Xa to activate prothrombin to thrombin; Belongs to the multicopper oxidase family. (2258 aa) |
| | PENK | Proenkephalin. (274 aa) |
| | DNAJC5B | DnaJ homolog subfamily C member 5B. (199 aa) |
| | TOR4A | Torsin family 4 member A. (415 aa) |
| | DBH | Dopamine beta-hydroxylase. (610 aa) |
| | ACTL7A | Actin like 7A; Belongs to the actin family. (439 aa) |
| | ANKS6 | Ankyrin repeat and SAM domain-containing protein 6 isoform X3. (874 aa) |
| | F1SP87_PIG | Uncharacterized protein. (141 aa) |
| | SERPINB10 | SERPIN domain-containing protein; Belongs to the serpin family. (397 aa) |
| | SCG5 | Neuroendocrine protein 7B2; Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro. (211 aa) |
| | THBS1 | Uncharacterized protein. (1170 aa) |
| | SPACA1 | Sperm acrosome membrane-associated protein 1; Plays a role in acrosome expansion and establishment of normal sperm morphology during spermatogenesis. Important for male fertility. (295 aa) |
| | SLC35D3 | Solute carrier family 35 member D3. (423 aa) |
| | PADI6 | Protein-arginine deiminase type-6. (687 aa) |
| | SPACA6 | Sperm acrosome associated 6. (323 aa) |
| | LOC100515551 | Uncharacterized protein. (551 aa) |
| | CD177 | CD177 molecule. (438 aa) |
| | RAB4B | Uncharacterized protein. (228 aa) |
| | KRTDAP | Keratinocyte differentiation-associated protein isoform 1. (99 aa) |
| | EXOC3L1 | Exocyst complex component 3 like 1. (744 aa) |
| | CTSH | Cathepsin H heavy chain; Important for the overall degradation of proteins in lysosomes; Belongs to the peptidase C1 family. (335 aa) |
| | CRISP1 | Cysteine rich secretory protein 1; Belongs to the CRISP family. (249 aa) |
| | CRISP2 | Cysteine-rich secretory protein 2 isoform X1; Belongs to the CRISP family. (244 aa) |
| | TREML1 | Triggering receptor expressed on myeloid cells like 1. (310 aa) |
| | RAB44 | RAB44, member RAS oncogene family. (984 aa) |
| | SYT1 | Synaptotagmin 1. (379 aa) |
| | IGF1 | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (230 aa) |
| | CRACR2A | Calcium release activated channel regulator 2A. (872 aa) |
| | VWF | Von Willebrand factor; Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet- surface receptor complex, glycoprotein Ibalpha/IX/V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma (By similarity). (2940 aa) |
| | ACRBP | Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin. (539 aa) |
| | SYT10 | Synaptotagmin-10. (523 aa) |
| | RAB3IP | Uncharacterized protein. (479 aa) |
| | PDE4B | Phosphodiesterase. (736 aa) |
| | MYRIP | Myosin VIIA and Rab interacting protein. (856 aa) |
| | RAB4A | RAB4A, member RAS oncogene family. (223 aa) |
| | ENSSSCP00000073689 | annotation not available (469 aa) |
| | CYB561 | Cytochrome b561; Secretory vesicle-specific electron transport protein. (259 aa) |
| | GMFG | Glia maturation factor gamma. (195 aa) |
| | CHGA | p-Glu serpinin precursor; [Pancreastatin]: Strongly inhibits glucose induced insulin release from the pancreas. [Catestatin]: Inhibits catecholamine release from chromaffin cells and noradrenergic neurons by acting as a non-competitive nicotinic cholinergic antagonist. Can induce mast cell migration, degranulation and production of cytokines and chemokines. Belongs to the chromogranin/secretogranin protein family. (596 aa) |
| | A0A5G2R4X1_PIG | Uncharacterized protein. (88 aa) |
| | A0A5G2R3N8_PIG | Uncharacterized protein. (135 aa) |
| | RAB37 | RAB37, member RAS oncogene family. (294 aa) |
| | RIMS2 | Regulating synaptic membrane exocytosis 2. (1348 aa) |
| | F13A1 | Coagulation factor XIII A chain. (774 aa) |
| | VAMP2 | V-SNARE coiled-coil homology domain-containing protein. (189 aa) |
| | A0A5G2R2G3_PIG | Uncharacterized protein. (3809 aa) |
| | MCTP1 | Multiple C2 and transmembrane domain containing 1. (995 aa) |
| | LOC100736569 | Uncharacterized protein. (428 aa) |
| | SLC18A1 | Solute carrier family 18 member A1. (524 aa) |
| | A0A5G2QZ07_PIG | GRIP domain-containing protein. (469 aa) |
| | RAB40B | RAB40B, member RAS oncogene family. (453 aa) |
| | ARSA | Sulfatase domain-containing protein. (519 aa) |
| | ENSSSCP00000069602 | annotation not available (97 aa) |
| | RAB3C | RAB3C, member RAS oncogene family. (235 aa) |
| | SH3GL3 | SH3 domain containing GRB2 like 3, endophilin A3. (512 aa) |
| | FRMPD4 | FERM and PDZ domain containing 4. (1330 aa) |
| | VPS13A | Vacuolar protein sorting 13 homolog A. (3171 aa) |
| | ZAN | Zonadhesin; Binds in a species-specific manner to the zona pellucida of the egg. May be involved in gamete recognition and/or signaling. (2676 aa) |
| | TPRG1L | HSac2 domain-containing protein. (277 aa) |
| | ZPBP2 | Zona pellucida binding protein 2. (363 aa) |
| | SYNGR3 | Synaptogyrin. (253 aa) |
| | SLC17A7 | Solute carrier family 17 member 7. (567 aa) |
| | TMEM184A | Transmembrane protein 184A. (482 aa) |
| | A0A5G2QL47_PIG | Uncharacterized protein. (116 aa) |
| | PHACTR2 | Phosphatase and actin regulator. (759 aa) |
| | TSPOAP1 | TSPO associated protein 1. (1855 aa) |
| | RESP18 | RESP18 domain-containing protein. (255 aa) |
| | TMEM100 | Transmembrane protein 100 isoform X1. (134 aa) |
| | A0A5G2QP39_PIG | Uncharacterized protein. (316 aa) |
| | A0A5G2RF62_PIG | Uncharacterized protein. (97 aa) |
| | ICA1 | Islet cell autoantigen 1. (572 aa) |
| | SPINK5 | Serine peptidase inhibitor, Kazal type 5. (1023 aa) |
| | RAB3IL1 | RAB3A interacting protein like 1. (461 aa) |
| | A0A5G2QET8_PIG | GRIP domain-containing protein. (461 aa) |
| | A0A5G2RMB4_PIG | GRIP domain-containing protein. (469 aa) |
| | PLEKHO2 | PH domain-containing protein. (504 aa) |
| | SYNGR2 | Synaptogyrin. (226 aa) |
| | RPH3A | Rabphilin-3A isoform 1. (701 aa) |
| | LOC102166000 | Uncharacterized protein. (1419 aa) |
| | SYNGR1 | Synaptogyrin. (234 aa) |
| | SYN2 | Synapsin II. (581 aa) |
| | COMMD9 | COMM domain containing 9. (197 aa) |
| | RAB10 | Uncharacterized protein. (201 aa) |
| | ANXA8 | Annexin. (354 aa) |
| | A0A5G2QDR5_PIG | C2H2-type domain-containing protein. (1821 aa) |
| | RAB1A | Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] (217 aa) |
| | TMEM184B | Transmembrane protein 184B. (424 aa) |
| | DNASE1 | Deoxyribonuclease-1; Serum endocuclease secreted into body fluids by a wide variety of exocrine and endocrine organs. Expressed by non-hematopoietic tissues and preferentially cleaves protein-free DNA (By similarity). Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization (By similarity). Together with DNASE1L3, plays a key role in degrading neutrophil extracellular traps (NETs) (By similarity). NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation (By s [...] (284 aa) |
| | KIAA1210 | Uncharacterized protein. (1669 aa) |
| | ABCA12 | ATP binding cassette subfamily A member 12. (2593 aa) |
| | MME | Neprilysin; Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. Belongs to the peptidase M13 family. (750 aa) |
| | IZUMO1 | Izumo sperm-egg fusion 1. (322 aa) |
| | RAB40C | Ras-related protein Rab-40C isoform a. (281 aa) |
| | STK11IP | Serine/threonine kinase 11 interacting protein. (1070 aa) |
| | RAB3D | RAB3D, member RAS oncogene family. (218 aa) |
| | FRMPD3 | FERM and PDZ domain containing 3. (1760 aa) |
| | NGF | Beta-nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (By similarity). The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone colla [...] (385 aa) |
| | BRI3 | Brain protein I3. (125 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2680 aa) |
| | DNASE1L1 | Deoxyribonuclease-1-like 1. (315 aa) |
| | LGI3 | Leucine rich repeat LGI family member 3. (661 aa) |
| | DNASE1L3 | Deoxyribonuclease; Belongs to the DNase I family. (312 aa) |
| | PRRT2 | Proline-rich transmembrane protein 2 isoform 3. (406 aa) |
| | WFS1 | Wolframin ER transmembrane glycoprotein. (889 aa) |
| | SPINK2 | Serine protease inhibitor Kazal-type 2 isoform 1. (85 aa) |
| | VEGFA | Vascular endothelial growth factor A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity). Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By s [...] (451 aa) |
| | TCTEX1D4 | Tctex1 domain-containing protein 4. (218 aa) |
| | STXBP5 | Syntaxin binding protein 5. (1179 aa) |
| | STXBP2 | Syntaxin-binding protein 2; Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells (By similarity); Belongs to the STXBP/unc-18/SEC1 family. (650 aa) |
| | TMEM190 | Transmembrane protein 190. (181 aa) |
| | GALNS | N-acetylgalactosamine-6-sulfatase. (626 aa) |
| | HYAL3 | Hyaluronidase-3; Facilitates sperm penetration into the layer of cumulus cells surrounding the egg by digesting hyaluronic acid. Involved in induction of the acrosome reaction in the sperm. Involved in follicular atresia, the breakdown of immature ovarian follicles that are not selected to ovulate. Induces ovarian granulosa cell apoptosis, possibly via apoptotic signaling pathway involving CASP8 and CASP3 activation, and poly(ADP-ribose) polymerase (PARP) cleavage. Has no hyaluronidase activity in embryonic fibroblasts in vitro. Has no hyaluronidase activity in granulosa cells in vitro. (490 aa) |
| | RHOG | Uncharacterized protein. (394 aa) |
| | SPESP1 | Uncharacterized protein. (352 aa) |
| | DOC2A | Double C2 domain alpha. (487 aa) |
| | REXO1 | RNA exonuclease 1 homolog. (1321 aa) |
| | SFTPB | Pulmonary surfactant-associated protein B; Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter. (379 aa) |
| | SEMA4C | Semaphorin 4C; Belongs to the semaphorin family. (896 aa) |
| | PPT1 | Palmitoyl-protein thioesterase 1. (305 aa) |
| | LOC100514786 | ABC transporter domain-containing protein. (3220 aa) |
| | SERPINE2 | SERPIN domain-containing protein; Belongs to the serpin family. (378 aa) |
| | GLIPR1 | GLI pathogenesis related 1; Belongs to the CRISP family. (302 aa) |
| | FAM3C | Family with sequence similarity 3 member C. (227 aa) |
| | SYT7 | Synaptotagmin-7 isoform X2. (686 aa) |
| | SVOP | SV2 related protein. (551 aa) |
| | PLA2G10 | Phospholipase A(2). (188 aa) |
| | LOC100524794 | Uncharacterized protein. (1662 aa) |
| | TMEM179B | Transmembrane protein 179B. (218 aa) |
| | BDNF | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (260 aa) |
| | CABS1 | Calcium binding protein, spermatid associated 1. (400 aa) |
| | RNF112 | Ring finger protein 112. (628 aa) |
| | NUDT1 | Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. (277 aa) |
| | GRP | Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones. Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity); Belongs to the bombesin/neuromedin-B/ranatensin family. (146 aa) |
| | SV2C | Synaptic vesicle glycoprotein 2C isoform X1. (724 aa) |
| | KLK7 | Kallikrein related peptidase 7; Belongs to the peptidase S1 family. (257 aa) |
| | ABCA3 | ATP binding cassette subfamily A member 3. (1787 aa) |
| | RAB6A | RAB6A, member RAS oncogene family. (254 aa) |
| | SV2B | Synaptic vesicle glycoprotein 2B. (683 aa) |
| | ENPP4 | Ectonucleotide pyrophosphatase/phosphodiesterase 4. (453 aa) |
| | LY6K | UPAR/Ly6 domain-containing protein. (157 aa) |
| | SCG3 | Secretogranin III. (549 aa) |
| | ICA1L | Islet cell autoantigen 1 like. (490 aa) |
| | PRSS51 | Serine protease 51; Belongs to the peptidase S1 family. (266 aa) |
| | STX4 | Syntaxin 4; Belongs to the syntaxin family. (338 aa) |
| | SLC30A8 | Solute carrier family 30 member 8. (369 aa) |
| | MFGE8 | Lactadherin; Contributes to phagocytic removal of apoptotic cells in many tissues. Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. (492 aa) |
| | RABL3 | RAB, member of RAS oncogene family like 3. (267 aa) |
| | CD46 | Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. May act as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. (381 aa) |
| | CLUL1 | Clusterin; Belongs to the clusterin family. (469 aa) |
| | ACR | Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. (414 aa) |
| | SPACA7 | Uncharacterized protein. (216 aa) |
| | TEX101 | Uncharacterized protein. (248 aa) |
| | NHLRC3 | NHL repeat containing 3. (435 aa) |
| | A0A287ADW3_PIG | Uncharacterized protein. (347 aa) |
| | STX6 | Syntaxin 6; Belongs to the syntaxin family. (306 aa) |
| | CDKN2AIPNL | XRN2-binding (XTBD) domain-containing protein. (116 aa) |
| | LOC100525027 | Uncharacterized protein. (376 aa) |
| | NPY | C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone; Belongs to the NPY family. (169 aa) |
| | LY6G6D | Ig-like domain-containing protein. (445 aa) |
| | SCG2 | Secretogranin-2; Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules. (616 aa) |
| | GMFB | Glia maturation factor; Belongs to the actin-binding proteins ADF family. GMF subfamily. (136 aa) |
| | KLK6 | Kallikrein related peptidase 6; Belongs to the peptidase S1 family. (246 aa) |
| | TEX22 | Testis expressed 22. (151 aa) |
| | PAM | Peptidyl-glycine alpha-amidating monooxygenase isoform X1. (972 aa) |
| | TMEM11 | Transmembrane protein 11. (292 aa) |
| | ATP2B1 | Plasma membrane calcium-transporting ATPase 1; Catalyzes the hydrolysis of ATP coupled with the transport of calcium from the cytoplasm to the extracellular space thereby maintaining intracellular calcium homeostasis. Plays a role in blood pressure regulation through regulation of intracellular calcium concentration and nitric oxide production leading to regulation of vascular smooth muscle cells vasoconstriction. Positively regulates bone mineralization through absorption of calcium from the intestine. Plays dual roles in osteoclast differentiation and survival by regulating RANKL-ind [...] (1249 aa) |
| | CTSW | Cathepsin W; Belongs to the peptidase C1 family. (368 aa) |
| | RAB15 | RAB15, member RAS oncogene family. (197 aa) |
| | TRIP11 | Thyroid hormone receptor interactor 11. (1974 aa) |
| | ANXA13 | Annexin. (357 aa) |
| | DCLK2 | Doublecortin like kinase 2. (791 aa) |
