STRINGSTRING
A0A5G2RMB4_PIG A0A5G2RMB4_PIG RAB3IP RAB3IP SYT10 SYT10 ACRBP ACRBP VWF VWF CRACR2A CRACR2A IGF1 IGF1 SYT1 SYT1 RAB44 RAB44 TREML1 TREML1 CRISP2 CRISP2 CRISP1 CRISP1 CTSH CTSH EXOC3L1 EXOC3L1 KRTDAP KRTDAP RAB4B RAB4B CD177 CD177 LOC100515551 LOC100515551 SPACA6 SPACA6 PADI6 PADI6 SLC35D3 SLC35D3 SPACA1 SPACA1 THBS1 THBS1 SCG5 SCG5 SERPINB10 SERPINB10 F1SP87_PIG F1SP87_PIG ANKS6 ANKS6 ACTL7A ACTL7A DBH DBH TOR4A TOR4A DNAJC5B DNAJC5B PENK PENK F5 F5 SV2A SV2A ADAM30 ADAM30 CD58 CD58 SLC6A17 SLC6A17 STXBP3 STXBP3 SLC32A1 SLC32A1 STX1A STX1A CCDC189 CCDC189 F1RPD0_PIG F1RPD0_PIG F1RPC9_PIG F1RPC9_PIG GP2 GP2 ASTL ASTL ANXA4 ANXA4 PPP4R3B PPP4R3B QPCT QPCT F1S151_PIG F1S151_PIG PLAC8 PLAC8 OLFM4 OLFM4 SFTPC SFTPC F1RJP7_PIG F1RJP7_PIG PRSS55 PRSS55 FAM170B FAM170B NHLRC2 NHLRC2 SYT2 SYT2 CTSV CTSV LYZL4 LYZL4 SPACA5 SPACA5 SYP SYP CYLC1 CYLC1 SYTL4 SYTL4 SLC17A6 SLC17A6 AZU1 AZU1 PRTN3 PRTN3 RAB11B RAB11B CALR CALR STX10 STX10 RAB8A RAB8A RAB3A RAB3A C1orf35 C1orf35 LMAN2 LMAN2 HEXB HEXB CRHBP CRHBP PCSK1 PCSK1 FSTL4 FSTL4 PCYOX1L PCYOX1L SYT9 SYT9 TMEM225 TMEM225 ACRV1 ACRV1 KIRREL3 KIRREL3 F1S342_PIG F1S342_PIG ZPBP ZPBP TMEM163 TMEM163 PTPRN PTPRN GTPBP2 GTPBP2 LRGUK LRGUK CCDC136 CCDC136 SPAM1 SPAM1 IQUB IQUB STK31 STK31 UNC13D UNC13D LYZL6 LYZL6 EPX EPX SPACA3 SPACA3 SLC2A4 SLC2A4 TMEM95 TMEM95 FSTL5 FSTL5 SYCN SYCN IQCF1 IQCF1 SYNJ2 SYNJ2 AMPH AMPH SYT8 SYT8 PRSS37 PRSS37 PCSK1N PCSK1N ANXA7 ANXA7 DISC1 DISC1 IQCF5 IQCF5 VAMP8 VAMP8 STX12 STX12 STX1B STX1B SPACA4 SPACA4 POMC POMC SPATA1 SPATA1 PRSS57 PRSS57 C6orf120 C6orf120 SCFD2 SCFD2 GCA GCA CATSPER3 CATSPER3 ITPR2 ITPR2 F1RSX1_PIG F1RSX1_PIG SYT5 SYT5 LTF LTF SLC30A3 SLC30A3 CATSPER4 CATSPER4 CRISP3 CRISP3 PRRT1 PRRT1 SYN1 SYN1 CFB CFB MPO MPO SNCA SNCA SLC17A8 SLC17A8 LHFPL2 LHFPL2 PPFIA3 PPFIA3 PTPRN2 PTPRN2 RAB12 RAB12 MT3 MT3 CACFD1 CACFD1 SYNPR SYNPR A0A286ZQA4_PIG A0A286ZQA4_PIG STON2 STON2 VPS13B VPS13B CHGB CHGB SPX SPX CXADR CXADR SYN3 SYN3 RAB5A RAB5A KLK5 KLK5 CLCN3 CLCN3 PRKACA PRKACA TMED10 TMED10 ECRG4 ECRG4 SLC17A9 SLC17A9 RIMBP2 RIMBP2 SERPINB12 SERPINB12 TMPRSS12 TMPRSS12 DCLK2 DCLK2 SCNN1A SCNN1A ANXA13 ANXA13 TRIP11 TRIP11 RAB15 RAB15 CTSW CTSW ATP2B1 ATP2B1 TMEM11 TMEM11 PAM PAM TEX22 TEX22 KLK6 KLK6 GMFB GMFB SCG2 SCG2 LY6G6D LY6G6D NPY NPY LOC100525027 LOC100525027 CDKN2AIPNL CDKN2AIPNL STX6 STX6 A0A287ADW3_PIG A0A287ADW3_PIG NHLRC3 NHLRC3 TEX101 TEX101 SPACA7 SPACA7 ACR ACR CLUL1 CLUL1 CD46 CD46 RABL3 RABL3 MFGE8 MFGE8 SLC30A8 SLC30A8 STX4 STX4 PRSS51 PRSS51 ICA1L ICA1L SCG3 SCG3 LY6K LY6K ENPP4 ENPP4 SV2B SV2B RAB6A RAB6A ABCA3 ABCA3 KLK7 KLK7 SV2C SV2C GRP GRP NUDT1 NUDT1 RNF112 RNF112 CABS1 CABS1 BDNF BDNF TMEM179B TMEM179B LOC100524794 LOC100524794 PLA2G10 PLA2G10 SVOP SVOP SYT7 SYT7 FAM3C FAM3C GLIPR1 GLIPR1 SERPINE2 SERPINE2 LOC100514786 LOC100514786 PPT1 PPT1 SEMA4C SEMA4C SFTPB SFTPB REXO1 REXO1 DOC2A DOC2A SPESP1 SPESP1 RHOG RHOG HYAL3 HYAL3 GALNS GALNS TMEM190 TMEM190 STXBP2 STXBP2 STXBP5 STXBP5 TCTEX1D4 TCTEX1D4 VEGFA VEGFA SPINK2 SPINK2 WFS1 WFS1 PRRT2 PRRT2 DNASE1L3 DNASE1L3 LGI3 LGI3 DNASE1L1 DNASE1L1 ITPR3 ITPR3 BRI3 BRI3 NGF NGF FRMPD3 FRMPD3 RAB3D RAB3D STK11IP STK11IP RAB40C RAB40C IZUMO1 IZUMO1 MME MME ABCA12 ABCA12 KIAA1210 KIAA1210 DNASE1 DNASE1 TMEM184B TMEM184B RAB1A RAB1A A0A5G2QDR5_PIG A0A5G2QDR5_PIG ANXA8 ANXA8 RAB10 RAB10 COMMD9 COMMD9 SYN2 SYN2 SYNGR1 SYNGR1 LOC102166000 LOC102166000 RPH3A RPH3A SYNGR2 SYNGR2 PLEKHO2 PLEKHO2 A0A5G2QET8_PIG A0A5G2QET8_PIG RAB3IL1 RAB3IL1 SPINK5 SPINK5 ICA1 ICA1 A0A5G2RF62_PIG A0A5G2RF62_PIG A0A5G2QP39_PIG A0A5G2QP39_PIG TMEM100 TMEM100 RESP18 RESP18 TSPOAP1 TSPOAP1 PHACTR2 PHACTR2 A0A5G2QL47_PIG A0A5G2QL47_PIG TMEM184A TMEM184A SLC17A7 SLC17A7 SYNGR3 SYNGR3 ZPBP2 ZPBP2 TPRG1L TPRG1L ZAN ZAN VPS13A VPS13A FRMPD4 FRMPD4 SH3GL3 SH3GL3 RAB3C RAB3C ENSSSCP00000069602 ENSSSCP00000069602 ARSA ARSA RAB40B RAB40B A0A5G2QZ07_PIG A0A5G2QZ07_PIG SLC18A1 SLC18A1 LOC100736569 LOC100736569 MCTP1 MCTP1 A0A5G2R2G3_PIG A0A5G2R2G3_PIG VAMP2 VAMP2 F13A1 F13A1 RIMS2 RIMS2 RAB37 RAB37 A0A5G2R3N8_PIG A0A5G2R3N8_PIG A0A5G2R4X1_PIG A0A5G2R4X1_PIG CHGA CHGA GMFG GMFG CYB561 CYB561 ENSSSCP00000073689 ENSSSCP00000073689 RAB4A RAB4A MYRIP MYRIP PDE4B PDE4B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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A0A5G2RMB4_PIGGRIP domain-containing protein. (469 aa)
RAB3IPUncharacterized protein. (479 aa)
SYT10Synaptotagmin-10. (523 aa)
ACRBPAcrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin. (539 aa)
VWFVon Willebrand factor; Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet- surface receptor complex, glycoprotein Ibalpha/IX/V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma (By similarity). (2940 aa)
CRACR2ACalcium release activated channel regulator 2A. (872 aa)
IGF1Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (230 aa)
SYT1Synaptotagmin 1. (379 aa)
RAB44RAB44, member RAS oncogene family. (984 aa)
TREML1Triggering receptor expressed on myeloid cells like 1. (310 aa)
CRISP2Cysteine-rich secretory protein 2 isoform X1; Belongs to the CRISP family. (244 aa)
CRISP1Cysteine rich secretory protein 1; Belongs to the CRISP family. (249 aa)
CTSHCathepsin H heavy chain; Important for the overall degradation of proteins in lysosomes; Belongs to the peptidase C1 family. (335 aa)
EXOC3L1Exocyst complex component 3 like 1. (744 aa)
KRTDAPKeratinocyte differentiation-associated protein isoform 1. (99 aa)
RAB4BUncharacterized protein. (228 aa)
CD177CD177 molecule. (438 aa)
LOC100515551Uncharacterized protein. (551 aa)
SPACA6Sperm acrosome associated 6. (323 aa)
PADI6Protein-arginine deiminase type-6. (687 aa)
SLC35D3Solute carrier family 35 member D3. (423 aa)
SPACA1Sperm acrosome membrane-associated protein 1; Plays a role in acrosome expansion and establishment of normal sperm morphology during spermatogenesis. Important for male fertility. (295 aa)
THBS1Uncharacterized protein. (1170 aa)
SCG5Neuroendocrine protein 7B2; Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro. (211 aa)
SERPINB10SERPIN domain-containing protein; Belongs to the serpin family. (397 aa)
F1SP87_PIGUncharacterized protein. (141 aa)
ANKS6Ankyrin repeat and SAM domain-containing protein 6 isoform X3. (874 aa)
ACTL7AActin like 7A; Belongs to the actin family. (439 aa)
DBHDopamine beta-hydroxylase. (610 aa)
TOR4ATorsin family 4 member A. (415 aa)
DNAJC5BDnaJ homolog subfamily C member 5B. (199 aa)
PENKProenkephalin. (274 aa)
F5Coagulation factor V heavy chain; Coagulation factor V is a cofactor that participates with factor Xa to activate prothrombin to thrombin; Belongs to the multicopper oxidase family. (2258 aa)
SV2ASynaptic vesicle glycoprotein 2A isoform 1. (742 aa)
ADAM30ADAM metallopeptidase domain 30. (727 aa)
CD58Uncharacterized protein. (243 aa)
SLC6A17Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (727 aa)
STXBP3Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (940 aa)
SLC32A1Vesicular inhibitory amino acid transporter. (526 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (295 aa)
CCDC189Coiled-coil domain-containing protein 189 isoform X1. (336 aa)
F1RPD0_PIGUncharacterized protein. (1631 aa)
F1RPC9_PIGABC transporter domain-containing protein. (586 aa)
GP2Pancreatic secretory granule membrane major glycoprotein GP2 isoform 1. (532 aa)
ASTLMetalloendopeptidase. (392 aa)
ANXA4Annexin A4; Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis; Belongs to the annexin family. (337 aa)
PPP4R3BSerine/threonine-protein phosphatase 4 regulatory subunit 3B isoform 3. (820 aa)
QPCTGlutaminyl-peptide cyclotransferase. (361 aa)
F1S151_PIGUncharacterized protein. (59 aa)
PLAC8Uncharacterized protein. (161 aa)
OLFM4Olfactomedin 4. (488 aa)
SFTPCPulmonary surfactant-associated protein C; Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. (208 aa)
F1RJP7_PIGPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (293 aa)
PRSS55Serine protease 55; Belongs to the peptidase S1 family. (337 aa)
FAM170BFamily with sequence similarity 170 member B. (286 aa)
NHLRC2NHL repeat-containing protein 2. (725 aa)
SYT2Synaptotagmin 2. (417 aa)
CTSVCathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (By similarity). Belongs to the peptidase C1 family. (334 aa)
LYZL4Lysozyme like 4; Belongs to the glycosyl hydrolase 22 family. (145 aa)
SPACA5Sperm acrosome associated 5; Belongs to the glycosyl hydrolase 22 family. (160 aa)
SYPSynaptophysin. (319 aa)
CYLC1Cylicin 1. (650 aa)
SYTL4Synaptotagmin like 4. (721 aa)
SLC17A6Solute carrier family 17 member 6. (582 aa)
AZU1Azurocidin; This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin; Belongs to the peptidase S1 family. Elastase subfamily. (246 aa)
PRTN3Proteinase 3; Belongs to the peptidase S1 family. (268 aa)
RAB11BUncharacterized protein. (205 aa)
CALRCalreticulin; Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis; Belongs to the calreticulin family. (417 aa)
STX10Syntaxin 10; Belongs to the syntaxin family. (353 aa)
RAB8AUncharacterized protein. (242 aa)
RAB3ARas-related protein Rab-3A; Small GTP-binding protein that plays a central role in regulated exocytosis and secretion. Controls the recruitment, tethering and docking of secretory vesicles to the plasma membrane (By similarity). Upon stimulation, switches to its active GTP-bound form, cycles to vesicles and recruits effectors such as RIMS1, RIMS2, Rabphilin-3A/RPH3A, RPH3AL or SYTL4 to help the docking of vesicules onto the plasma membrane (By similarity). Upon GTP hydrolysis by GTPase-activating protein, dissociates from the vesicle membrane allowing the exocytosis to proceed (By simi [...] (254 aa)
C1orf35Multiple myeloma tumor-associated protein 2. (237 aa)
LMAN2Lectin, mannose binding 2. (359 aa)
HEXBBeta-hexosaminidase subunit beta; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. (538 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
PCSK1P/Homo B domain-containing protein; Belongs to the peptidase S8 family. (760 aa)
FSTL4Follistatin like 4. (848 aa)
PCYOX1LPrenylcysteine oxidase 1 like. (457 aa)
SYT9Synaptotagmin-9. (491 aa)
TMEM225Uncharacterized protein. (233 aa)
ACRV1Acrosomal vesicle protein 1. (272 aa)
KIRREL3Kirre like nephrin family adhesion molecule 3. (794 aa)
F1S342_PIGUncharacterized protein. (332 aa)
ZPBPZona pellucida-binding protein 1; Plays a role in acrosome compaction and sperm morphogenesis. Is implicated in sperm-oocyte interaction during fertilization. Belongs to the zona pellucida-binding protein Sp38 family. (350 aa)
TMEM163Transmembrane protein 163. (287 aa)
PTPRNProtein tyrosine phosphatase receptor type N. (978 aa)
GTPBP2GTP binding protein 2. (694 aa)
LRGUKLeucine rich repeats and guanylate kinase domain containing. (815 aa)
CCDC136Coiled-coil domain containing 136. (1160 aa)
SPAM1Hyaluronidase. (493 aa)
IQUBIQ motif and ubiquitin domain containing. (800 aa)
STK31Serine/threonine kinase 31. (983 aa)
UNC13DUnc-13 homolog D. (1090 aa)
LYZL6Lysozyme like 6; Belongs to the glycosyl hydrolase 22 family. (148 aa)
EPXEosinophil peroxidase heavy chain; Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils; Belongs to the peroxidase family. XPO subfamily. (705 aa)
SPACA3Uncharacterized protein; Belongs to the glycosyl hydrolase 22 family. (163 aa)
SLC2A4Solute carrier family 2, facilitated glucose transporter member 4; Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation. Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracellularly within storage compartments in muscle and fat cells. Upon insulin stimulation, translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu into the cell. (509 aa)
TMEM95Transmembrane protein 95. (184 aa)
FSTL5Follistatin like 5. (856 aa)
SYCNSyncollin. (136 aa)
IQCF1IQ motif containing F1. (207 aa)
SYNJ2Synaptojanin 2. (1402 aa)
AMPHUncharacterized protein. (678 aa)
SYT8Synaptotagmin 8. (381 aa)
PRSS37Putative inactive serine protease 37. (235 aa)
PCSK1NProprotein convertase subtilisin/kexin type 1 inhibitor. (259 aa)
ANXA7Annexin. (485 aa)
DISC1DISC1 scaffold protein. (819 aa)
IQCF5IQ motif containing F5. (149 aa)
VAMP8V-SNARE coiled-coil homology domain-containing protein. (143 aa)
STX12t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (369 aa)
STX1BSyntaxin 1B; Belongs to the syntaxin family. (288 aa)
SPACA4Sperm acrosome associated 4. (126 aa)
POMCCorticotropin-like intermediary peptide; [Corticotropin]: Stimulates the adrenal glands to release cortisol. [Melanocyte-stimulating hormone beta]: Increases the pigmentation of skin by increasing melanin production in melanocytes. [Met-enkephalin]: Endogenous opiate; Belongs to the POMC family. (381 aa)
SPATA1Spermatogenesis associated 1. (459 aa)
PRSS57Serine protease 57; Belongs to the peptidase S1 family. (279 aa)
C6orf120Chromosome 6 open reading frame 120. (184 aa)
SCFD2Sec1 family domain containing 2; Belongs to the STXBP/unc-18/SEC1 family. (684 aa)
GCAGrancalcin. (297 aa)
CATSPER3Ion_trans domain-containing protein. (425 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2702 aa)
F1RSX1_PIGUncharacterized protein. (200 aa)
SYT5Synaptotagmin 5. (385 aa)
LTFLactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity. Shows a preferential cleavage at -Arg-Ser-Arg-Arg-|- and -Arg-Arg-Ser-Arg-|-, and of Z-Phe-Arg-|-aminomethylcoumarin sites. (704 aa)
SLC30A3Uncharacterized protein. (464 aa)
CATSPER4Cation channel sperm associated 4. (471 aa)
CRISP3Cysteine rich secretory protein 3; Belongs to the CRISP family. (245 aa)
PRRT1Uncharacterized protein. (305 aa)
SYN1Synapsin-1 isoform Ia. (712 aa)
CFBComplement factor B; Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase; Belongs to the peptidase S1 family. (851 aa)
MPOMyeloperoxidase. (731 aa)
SNCAAlpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] (142 aa)
SLC17A8Solute carrier family 17 member 8. (544 aa)
LHFPL2LHFPL tetraspan subfamily member 2 protein isoform X1. (228 aa)
PPFIA3PTPRF interacting protein alpha 3. (1235 aa)
PTPRN2Protein tyrosine phosphatase receptor type N2. (1032 aa)
RAB12RAB12, member RAS oncogene family. (332 aa)
MT3Metallothionein-3; Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro (By similarity); Belongs to the metallothionein superfamily. Type 1 family. (95 aa)
CACFD1Calcium channel flower domain containing 1. (172 aa)
SYNPRSynaptoporin. (288 aa)
A0A286ZQA4_PIGUncharacterized protein. (275 aa)
STON2Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family. (955 aa)
VPS13BVacuolar protein sorting-associated protein 13B isoform X1. (4018 aa)
CHGBSecretogranin-1; Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides. (666 aa)
SPXSpexin hormone. (118 aa)
CXADRUncharacterized protein. (419 aa)
SYN3Synapsin III. (580 aa)
RAB5ARas-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] (215 aa)
KLK5Kallikrein related peptidase 5; Belongs to the peptidase S1 family. (295 aa)
CLCN3Chloride channel protein. (866 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose- mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the [...] (357 aa)
TMED10Transmembrane emp24 domain-containing protein 10. (219 aa)
ECRG4ECRG4 augurin precursor. (147 aa)
SLC17A9Solute carrier family 17 member 9. (600 aa)
RIMBP2RIMS-binding protein 2 isoform X2. (1496 aa)
SERPINB12Serpin family B member 12; Belongs to the serpin family. (425 aa)
TMPRSS12Transmembrane serine protease 12; Belongs to the peptidase S1 family. (366 aa)
DCLK2Doublecortin like kinase 2. (791 aa)
SCNN1AAmiloride-sensitive sodium channel subunit alpha isoform 2; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (650 aa)
ANXA13Annexin. (357 aa)
TRIP11Thyroid hormone receptor interactor 11. (1974 aa)
RAB15RAB15, member RAS oncogene family. (197 aa)
CTSWCathepsin W; Belongs to the peptidase C1 family. (368 aa)
ATP2B1Plasma membrane calcium-transporting ATPase 1; Catalyzes the hydrolysis of ATP coupled with the transport of calcium from the cytoplasm to the extracellular space thereby maintaining intracellular calcium homeostasis. Plays a role in blood pressure regulation through regulation of intracellular calcium concentration and nitric oxide production leading to regulation of vascular smooth muscle cells vasoconstriction. Positively regulates bone mineralization through absorption of calcium from the intestine. Plays dual roles in osteoclast differentiation and survival by regulating RANKL-ind [...] (1249 aa)
TMEM11Transmembrane protein 11. (292 aa)
PAMPeptidyl-glycine alpha-amidating monooxygenase isoform X1. (972 aa)
TEX22Testis expressed 22. (151 aa)
KLK6Kallikrein related peptidase 6; Belongs to the peptidase S1 family. (246 aa)
GMFBGlia maturation factor; Belongs to the actin-binding proteins ADF family. GMF subfamily. (136 aa)
SCG2Secretogranin-2; Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules. (616 aa)
LY6G6DIg-like domain-containing protein. (445 aa)
NPYC-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone; Belongs to the NPY family. (169 aa)
LOC100525027Uncharacterized protein. (376 aa)
CDKN2AIPNLXRN2-binding (XTBD) domain-containing protein. (116 aa)
STX6Syntaxin 6; Belongs to the syntaxin family. (306 aa)
A0A287ADW3_PIGUncharacterized protein. (347 aa)
NHLRC3NHL repeat containing 3. (435 aa)
TEX101Uncharacterized protein. (248 aa)
SPACA7Uncharacterized protein. (216 aa)
ACRAcrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. (414 aa)
CLUL1Clusterin; Belongs to the clusterin family. (469 aa)
CD46Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. May act as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. (381 aa)
RABL3RAB, member of RAS oncogene family like 3. (267 aa)
MFGE8Lactadherin; Contributes to phagocytic removal of apoptotic cells in many tissues. Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. (492 aa)
SLC30A8Solute carrier family 30 member 8. (369 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (338 aa)
PRSS51Serine protease 51; Belongs to the peptidase S1 family. (266 aa)
ICA1LIslet cell autoantigen 1 like. (490 aa)
SCG3Secretogranin III. (549 aa)
LY6KUPAR/Ly6 domain-containing protein. (157 aa)
ENPP4Ectonucleotide pyrophosphatase/phosphodiesterase 4. (453 aa)
SV2BSynaptic vesicle glycoprotein 2B. (683 aa)
RAB6ARAB6A, member RAS oncogene family. (254 aa)
ABCA3ATP binding cassette subfamily A member 3. (1787 aa)
KLK7Kallikrein related peptidase 7; Belongs to the peptidase S1 family. (257 aa)
SV2CSynaptic vesicle glycoprotein 2C isoform X1. (724 aa)
GRPGastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones. Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity); Belongs to the bombesin/neuromedin-B/ranatensin family. (146 aa)
NUDT1Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. (277 aa)
RNF112Ring finger protein 112. (628 aa)
CABS1Calcium binding protein, spermatid associated 1. (400 aa)
BDNFBrain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (260 aa)
TMEM179BTransmembrane protein 179B. (218 aa)
LOC100524794Uncharacterized protein. (1662 aa)
PLA2G10Phospholipase A(2). (188 aa)
SVOPSV2 related protein. (551 aa)
SYT7Synaptotagmin-7 isoform X2. (686 aa)
FAM3CFamily with sequence similarity 3 member C. (227 aa)
GLIPR1GLI pathogenesis related 1; Belongs to the CRISP family. (302 aa)
SERPINE2SERPIN domain-containing protein; Belongs to the serpin family. (378 aa)
LOC100514786ABC transporter domain-containing protein. (3220 aa)
PPT1Palmitoyl-protein thioesterase 1. (305 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (896 aa)
SFTPBPulmonary surfactant-associated protein B; Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter. (379 aa)
REXO1RNA exonuclease 1 homolog. (1321 aa)
DOC2ADouble C2 domain alpha. (487 aa)
SPESP1Uncharacterized protein. (352 aa)
RHOGUncharacterized protein. (394 aa)
HYAL3Hyaluronidase-3; Facilitates sperm penetration into the layer of cumulus cells surrounding the egg by digesting hyaluronic acid. Involved in induction of the acrosome reaction in the sperm. Involved in follicular atresia, the breakdown of immature ovarian follicles that are not selected to ovulate. Induces ovarian granulosa cell apoptosis, possibly via apoptotic signaling pathway involving CASP8 and CASP3 activation, and poly(ADP-ribose) polymerase (PARP) cleavage. Has no hyaluronidase activity in embryonic fibroblasts in vitro. Has no hyaluronidase activity in granulosa cells in vitro. (490 aa)
GALNSN-acetylgalactosamine-6-sulfatase. (626 aa)
TMEM190Transmembrane protein 190. (181 aa)
STXBP2Syntaxin-binding protein 2; Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells (By similarity); Belongs to the STXBP/unc-18/SEC1 family. (650 aa)
STXBP5Syntaxin binding protein 5. (1179 aa)
TCTEX1D4Tctex1 domain-containing protein 4. (218 aa)
VEGFAVascular endothelial growth factor A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity). Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By s [...] (451 aa)
SPINK2Serine protease inhibitor Kazal-type 2 isoform 1. (85 aa)
WFS1Wolframin ER transmembrane glycoprotein. (889 aa)
PRRT2Proline-rich transmembrane protein 2 isoform 3. (406 aa)
DNASE1L3Deoxyribonuclease; Belongs to the DNase I family. (312 aa)
LGI3Leucine rich repeat LGI family member 3. (661 aa)
DNASE1L1Deoxyribonuclease-1-like 1. (315 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2680 aa)
BRI3Brain protein I3. (125 aa)
NGFBeta-nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (By similarity). The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone colla [...] (385 aa)
FRMPD3FERM and PDZ domain containing 3. (1760 aa)
RAB3DRAB3D, member RAS oncogene family. (218 aa)
STK11IPSerine/threonine kinase 11 interacting protein. (1070 aa)
RAB40CRas-related protein Rab-40C isoform a. (281 aa)
IZUMO1Izumo sperm-egg fusion 1. (322 aa)
MMENeprilysin; Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. Belongs to the peptidase M13 family. (750 aa)
ABCA12ATP binding cassette subfamily A member 12. (2593 aa)
KIAA1210Uncharacterized protein. (1669 aa)
DNASE1Deoxyribonuclease-1; Serum endocuclease secreted into body fluids by a wide variety of exocrine and endocrine organs. Expressed by non-hematopoietic tissues and preferentially cleaves protein-free DNA (By similarity). Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization (By similarity). Together with DNASE1L3, plays a key role in degrading neutrophil extracellular traps (NETs) (By similarity). NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation (By s [...] (284 aa)
TMEM184BTransmembrane protein 184B. (424 aa)
RAB1ARas-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] (217 aa)
A0A5G2QDR5_PIGC2H2-type domain-containing protein. (1821 aa)
ANXA8Annexin. (354 aa)
RAB10Uncharacterized protein. (201 aa)
COMMD9COMM domain containing 9. (197 aa)
SYN2Synapsin II. (581 aa)
SYNGR1Synaptogyrin. (234 aa)
LOC102166000Uncharacterized protein. (1419 aa)
RPH3ARabphilin-3A isoform 1. (701 aa)
SYNGR2Synaptogyrin. (226 aa)
PLEKHO2PH domain-containing protein. (504 aa)
A0A5G2QET8_PIGGRIP domain-containing protein. (461 aa)
RAB3IL1RAB3A interacting protein like 1. (461 aa)
SPINK5Serine peptidase inhibitor, Kazal type 5. (1023 aa)
ICA1Islet cell autoantigen 1. (572 aa)
A0A5G2RF62_PIGUncharacterized protein. (97 aa)
A0A5G2QP39_PIGUncharacterized protein. (316 aa)
TMEM100Transmembrane protein 100 isoform X1. (134 aa)
RESP18RESP18 domain-containing protein. (255 aa)
TSPOAP1TSPO associated protein 1. (1855 aa)
PHACTR2Phosphatase and actin regulator. (759 aa)
A0A5G2QL47_PIGUncharacterized protein. (116 aa)
TMEM184ATransmembrane protein 184A. (482 aa)
SLC17A7Solute carrier family 17 member 7. (567 aa)
SYNGR3Synaptogyrin. (253 aa)
ZPBP2Zona pellucida binding protein 2. (363 aa)
TPRG1LHSac2 domain-containing protein. (277 aa)
ZANZonadhesin; Binds in a species-specific manner to the zona pellucida of the egg. May be involved in gamete recognition and/or signaling. (2676 aa)
VPS13AVacuolar protein sorting 13 homolog A. (3171 aa)
FRMPD4FERM and PDZ domain containing 4. (1330 aa)
SH3GL3SH3 domain containing GRB2 like 3, endophilin A3. (512 aa)
RAB3CRAB3C, member RAS oncogene family. (235 aa)
ENSSSCP00000069602annotation not available (97 aa)
ARSASulfatase domain-containing protein. (519 aa)
RAB40BRAB40B, member RAS oncogene family. (453 aa)
A0A5G2QZ07_PIGGRIP domain-containing protein. (469 aa)
SLC18A1Solute carrier family 18 member A1. (524 aa)
LOC100736569Uncharacterized protein. (428 aa)
MCTP1Multiple C2 and transmembrane domain containing 1. (995 aa)
A0A5G2R2G3_PIGUncharacterized protein. (3809 aa)
VAMP2V-SNARE coiled-coil homology domain-containing protein. (189 aa)
F13A1Coagulation factor XIII A chain. (774 aa)
RIMS2Regulating synaptic membrane exocytosis 2. (1348 aa)
RAB37RAB37, member RAS oncogene family. (294 aa)
A0A5G2R3N8_PIGUncharacterized protein. (135 aa)
A0A5G2R4X1_PIGUncharacterized protein. (88 aa)
CHGAp-Glu serpinin precursor; [Pancreastatin]: Strongly inhibits glucose induced insulin release from the pancreas. [Catestatin]: Inhibits catecholamine release from chromaffin cells and noradrenergic neurons by acting as a non-competitive nicotinic cholinergic antagonist. Can induce mast cell migration, degranulation and production of cytokines and chemokines. Belongs to the chromogranin/secretogranin protein family. (596 aa)
GMFGGlia maturation factor gamma. (195 aa)
CYB561Cytochrome b561; Secretory vesicle-specific electron transport protein. (259 aa)
ENSSSCP00000073689annotation not available (469 aa)
RAB4ARAB4A, member RAS oncogene family. (223 aa)
MYRIPMyosin VIIA and Rab interacting protein. (856 aa)
PDE4BPhosphodiesterase. (736 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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