(29 nodes) PAS domain network (Sus scrofa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HIF1A	Hypoxia-inducible factor 1-alpha isoform 1. (824 aa)
	PDE8A	Phosphodiesterase. (837 aa)
	NPAS4	Neuronal PAS domain protein 4. (803 aa)
	SIM2	Single-minded homolog 2 long isoform. (673 aa)
	NCOA3	Uncharacterized protein. (1296 aa)
	NPAS2	Neuronal PAS domain protein 2. (796 aa)
	EPAS1	Uncharacterized protein. (870 aa)
	ARNTL	Aryl hydrocarbon receptor nuclear translocator like. (633 aa)
	KCNH5	Potassium voltage-gated channel subfamily H member 5. (988 aa)
	KCNH8	Potassium voltage-gated channel subfamily H member 8. (1107 aa)
	PER2	Period circadian regulator 2. (1362 aa)
	NPAS3	Neuronal PAS domain protein 3. (944 aa)
	NCOA1	Nuclear receptor coactivator 1; Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone- dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a central role in creating m [...] (1441 aa)
	AHRR	Uncharacterized protein. (695 aa)
	NCOA2	Nuclear receptor coactivator. (1463 aa)
	KCNH1	Uncharacterized protein. (919 aa)
	PDE8B	Phosphodiesterase. (882 aa)
	PASK	PAS domain containing serine/threonine kinase. (1320 aa)
	ARNTL2	Aryl hydrocarbon receptor nuclear translocator like 2. (652 aa)
	KCNH7	Potassium voltage-gated channel subfamily H member 7. (1198 aa)
	PER1	Period circadian regulator 1. (1278 aa)
	KCNH4	Potassium voltage-gated channel subfamily H member 4. (1017 aa)
	PER3	PAS domain-containing protein. (376 aa)
	AHR	Aryl hydrocarbon receptor. (849 aa)
	KCNH3	Potassium voltage-gated channel subfamily H member 3. (1081 aa)
	KCNH6	Potassium voltage-gated channel subfamily H member 6. (993 aa)
	HIF3A	Hypoxia inducible factor 3 subunit alpha. (671 aa)
	NPAS1	Neuronal PAS domain protein 1. (594 aa)
	ARNT	Aryl hydrocarbon receptor nuclear translocator isoform X3. (790 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHR	AHRR	ENSSSCP00000022722	ENSSSCP00000044912	Aryl hydrocarbon receptor.	Uncharacterized protein.	0.554
AHR	ARNT	ENSSSCP00000022722	ENSSSCP00000007087	Aryl hydrocarbon receptor.	Aryl hydrocarbon receptor nuclear translocator isoform X3.	0.996
AHR	ARNTL	ENSSSCP00000022722	ENSSSCP00000051561	Aryl hydrocarbon receptor.	Aryl hydrocarbon receptor nuclear translocator like.	0.775
AHR	ARNTL2	ENSSSCP00000022722	ENSSSCP00000032065	Aryl hydrocarbon receptor.	Aryl hydrocarbon receptor nuclear translocator like 2.	0.775
AHR	NCOA1	ENSSSCP00000022722	ENSSSCP00000048096	Aryl hydrocarbon receptor.	Nuclear receptor coactivator 1; Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone- dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a central role in creating m [...]	0.532
AHR	NCOA2	ENSSSCP00000022722	ENSSSCP00000042311	Aryl hydrocarbon receptor.	Nuclear receptor coactivator.	0.532
AHR	NCOA3	ENSSSCP00000022722	ENSSSCP00000007946	Aryl hydrocarbon receptor.	Uncharacterized protein.	0.532
AHR	NPAS2	ENSSSCP00000022722	ENSSSCP00000008722	Aryl hydrocarbon receptor.	Neuronal PAS domain protein 2.	0.532
AHRR	AHR	ENSSSCP00000044912	ENSSSCP00000022722	Uncharacterized protein.	Aryl hydrocarbon receptor.	0.554
AHRR	ARNT	ENSSSCP00000044912	ENSSSCP00000007087	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator isoform X3.	0.857
AHRR	ARNTL	ENSSSCP00000044912	ENSSSCP00000051561	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator like.	0.775
AHRR	ARNTL2	ENSSSCP00000044912	ENSSSCP00000032065	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator like 2.	0.775
AHRR	NCOA1	ENSSSCP00000044912	ENSSSCP00000048096	Uncharacterized protein.	Nuclear receptor coactivator 1; Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone- dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a central role in creating m [...]	0.532
AHRR	NCOA2	ENSSSCP00000044912	ENSSSCP00000042311	Uncharacterized protein.	Nuclear receptor coactivator.	0.532
AHRR	NCOA3	ENSSSCP00000044912	ENSSSCP00000007946	Uncharacterized protein.	Uncharacterized protein.	0.532
AHRR	NPAS2	ENSSSCP00000044912	ENSSSCP00000008722	Uncharacterized protein.	Neuronal PAS domain protein 2.	0.532
ARNT	AHR	ENSSSCP00000007087	ENSSSCP00000022722	Aryl hydrocarbon receptor nuclear translocator isoform X3.	Aryl hydrocarbon receptor.	0.996
ARNT	AHRR	ENSSSCP00000007087	ENSSSCP00000044912	Aryl hydrocarbon receptor nuclear translocator isoform X3.	Uncharacterized protein.	0.857
ARNT	ARNTL	ENSSSCP00000007087	ENSSSCP00000051561	Aryl hydrocarbon receptor nuclear translocator isoform X3.	Aryl hydrocarbon receptor nuclear translocator like.	0.576
ARNT	ARNTL2	ENSSSCP00000007087	ENSSSCP00000032065	Aryl hydrocarbon receptor nuclear translocator isoform X3.	Aryl hydrocarbon receptor nuclear translocator like 2.	0.547