13 items (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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Your Input:
	ALOX12B	Arachidonate 12-lipoxygenase, 12R type. (698 aa)
	ALOXE3	Arachidonate lipoxygenase 3. (710 aa)
	LIPG	Lipase G, endothelial type. (501 aa)
	LIPC	Lipase C, hepatic type. (501 aa)
	ALOX15	Arachidonate 15-lipoxygenase; Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12- HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3. Probably plays an important role in the immune and inflammatory responses. Through the o [...] (786 aa)
	ALOX5	Arachidonate 5-lipoxygenase. (638 aa)
	DENND5A	DENN domain containing 5A. (1286 aa)
	PNLIP	Pancreatic triacylglycerol lipase. (464 aa)
	LPL	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans; Belongs to the AB hydrolase superfamily. Lipase family. (486 aa)
	DENND5B	DENN domain containing 5B. (1361 aa)
	LOXHD1	Lipoxygenase homology domains 1. (2278 aa)
	PNLIPRP1	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (465 aa)
	ALOX15B	Arachidonate 15-lipoxygenase type B. (718 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALOX12B	ALOX15B	ENSSSCP00000019047	ENSSSCP00000019045	Arachidonate 12-lipoxygenase, 12R type.	Arachidonate 15-lipoxygenase type B.	0.904
ALOX12B	ALOX5	ENSSSCP00000019047	ENSSSCP00000030319	Arachidonate 12-lipoxygenase, 12R type.	Arachidonate 5-lipoxygenase.	0.906
ALOX15	ALOX15B	ENSSSCP00000030128	ENSSSCP00000019045	Arachidonate 15-lipoxygenase; Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12- HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3. Probably plays an important role in the immune and inflammatory responses. Through the o [...]	Arachidonate 15-lipoxygenase type B.	0.720
ALOX15B	ALOX12B	ENSSSCP00000019045	ENSSSCP00000019047	Arachidonate 15-lipoxygenase type B.	Arachidonate 12-lipoxygenase, 12R type.	0.904
ALOX15B	ALOX15	ENSSSCP00000019045	ENSSSCP00000030128	Arachidonate 15-lipoxygenase type B.	Arachidonate 15-lipoxygenase; Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12- HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3. Probably plays an important role in the immune and inflammatory responses. Through the o [...]	0.720
ALOX15B	ALOX5	ENSSSCP00000019045	ENSSSCP00000030319	Arachidonate 15-lipoxygenase type B.	Arachidonate 5-lipoxygenase.	0.907
ALOX5	ALOX12B	ENSSSCP00000030319	ENSSSCP00000019047	Arachidonate 5-lipoxygenase.	Arachidonate 12-lipoxygenase, 12R type.	0.906
ALOX5	ALOX15B	ENSSSCP00000030319	ENSSSCP00000019045	Arachidonate 5-lipoxygenase.	Arachidonate 15-lipoxygenase type B.	0.907
LIPC	LIPG	ENSSSCP00000004953	ENSSSCP00000027699	Lipase C, hepatic type.	Lipase G, endothelial type.	0.907
LIPC	LPL	ENSSSCP00000004953	ENSSSCP00000057312	Lipase C, hepatic type.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans; Belongs to the AB hydrolase superfamily. Lipase family.	0.902
LIPC	PNLIP	ENSSSCP00000004953	ENSSSCP00000011355	Lipase C, hepatic type.	Pancreatic triacylglycerol lipase.	0.908
LIPC	PNLIPRP1	ENSSSCP00000004953	ENSSSCP00000011357	Lipase C, hepatic type.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.919
LIPG	LIPC	ENSSSCP00000027699	ENSSSCP00000004953	Lipase G, endothelial type.	Lipase C, hepatic type.	0.907
LIPG	LPL	ENSSSCP00000027699	ENSSSCP00000057312	Lipase G, endothelial type.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans; Belongs to the AB hydrolase superfamily. Lipase family.	0.902
LIPG	PNLIP	ENSSSCP00000027699	ENSSSCP00000011355	Lipase G, endothelial type.	Pancreatic triacylglycerol lipase.	0.904
LIPG	PNLIPRP1	ENSSSCP00000027699	ENSSSCP00000011357	Lipase G, endothelial type.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.916
LPL	LIPC	ENSSSCP00000057312	ENSSSCP00000004953	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans; Belongs to the AB hydrolase superfamily. Lipase family.	Lipase C, hepatic type.	0.902
LPL	LIPG	ENSSSCP00000057312	ENSSSCP00000027699	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans; Belongs to the AB hydrolase superfamily. Lipase family.	Lipase G, endothelial type.	0.902
LPL	PNLIP	ENSSSCP00000057312	ENSSSCP00000011355	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans; Belongs to the AB hydrolase superfamily. Lipase family.	Pancreatic triacylglycerol lipase.	0.910
LPL	PNLIPRP1	ENSSSCP00000057312	ENSSSCP00000011357	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans; Belongs to the AB hydrolase superfamily. Lipase family.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.911