STRINGSTRING
ALX1 ALX1 POU6F1 POU6F1 HOXC13 HOXC13 HOXC12 HOXC12 POU5F1 POU5F1 NKX2-8 NKX2-8 VSX2 VSX2 GSC GSC ZFHX3 ZFHX3 IRX6 IRX6 IRX3 IRX3 MEIS3 MEIS3 POU3F1 POU3F1 DMBX1 DMBX1 ONECUT2 ONECUT2 CERS3 CERS3 RAX RAX OTX2 OTX2 SIX6 SIX6 SIX1 SIX1 PRRX2 PRRX2 BARHL1 BARHL1 ZHX1 ZHX1 BARHL2 BARHL2 NKX2-4 NKX2-4 BARX1 BARX1 LBX2 LBX2 EMX1 EMX1 VAX2 VAX2 SIX2 SIX2 HMX1 HMX1 MSX1 MSX1 GSX2 GSX2 NKX6-1 NKX6-1 GSX1 GSX1 CDX2 CDX2 HMBOX1 HMBOX1 CUX2 CUX2 LHX5 LHX5 HNF1A HNF1A GSC2 GSC2 NKX2-3 NKX2-3 PITX3 PITX3 VAX1 VAX1 HMX2 HMX2 NKX1-2 NKX1-2 SATB1 SATB1 POU1F1 POU1F1 POU3F4 POU3F4 DBX1 DBX1 ONECUT3 ONECUT3 CERS4 CERS4 OTP OTP POU4F3 POU4F3 PHOX2A PHOX2A BSX BSX MEOX2 MEOX2 LHX4 LHX4 EN1 EN1 DLX2 DLX2 HOXD13 HOXD13 HOXD12 HOXD12 HOXD10 HOXD10 HOXD9 HOXD9 HOXD4 HOXD4 HOXD3 HOXD3 HOXD1 HOXD1 GBX2 GBX2 MNX1 MNX1 EVX1 EVX1 HOXA11 HOXA11 HOXA5 HOXA5 HOXA4 HOXA4 CDX4 CDX4 POU4F2 POU4F2 POU2F3 POU2F3 TSHZ3 TSHZ3 SHOX2 SHOX2 TLX2 TLX2 PAX3 PAX3 HOXA9 HOXA9 PBX4 PBX4 LBX1 LBX1 PROP1 PROP1 VSX1 VSX1 EVX2 EVX2 HOMEZ HOMEZ PKNOX2 PKNOX2 HOXA7 HOXA7 TGIF1 TGIF1 HOXA3 HOXA3 HOXA2 HOXA2 DLX3 DLX3 HOXB13 HOXB13 HOXB5 HOXB5 HOXB6 HOXB6 HOXB7 HOXB7 HOXB8 HOXB8 HOXB4 HOXB4 HOXB3 HOXB3 HOXB2 HOXB2 HOXB1 HOXB1 MEOX1 MEOX1 IRX4 IRX4 TLX3 TLX3 ISL1 ISL1 HOXA1 HOXA1 CRX CRX HLX HLX ZHX2 ZHX2 PAX4 PAX4 HOPX HOPX HNF1B HNF1B A0A5G2QU24_PIG A0A5G2QU24_PIG DPRX DPRX CUX1 CUX1 LOC102157657 LOC102157657 LHX6 LHX6 ADNP2 ADNP2 PAX7 PAX7 POU2F2 POU2F2 HOXC6 HOXC6 SMYD5 SMYD5 PHOX2B PHOX2B NKX6-2 NKX6-2 POU2F1 POU2F1 NKX3-1 NKX3-1 LMX1A LMX1A NANOG NANOG ZFHX4 ZFHX4 TLX1 TLX1 HOXD8 HOXD8 HOXB9 HOXB9 NKX2-1 NKX2-1 IRX2 IRX2 ISL2 ISL2 NKX2-2 NKX2-2 MSX2 MSX2 HOXD11 HOXD11 HMX3 HMX3 POU4F1 POU4F1 CERS6 CERS6 PDX1 PDX1 ISX ISX HESX1 HESX1 HOXC11 HOXC11 CERS5 CERS5 POU3F3 POU3F3 MIXL1 MIXL1 HOXA13 HOXA13 SATB2 SATB2 HOXC10 HOXC10 SEBOX SEBOX NOBOX NOBOX MKX MKX ZEB1 ZEB1 RAX2 RAX2 ZFHX2 ZFHX2 PBX2 PBX2 IRX5 IRX5 HHEX HHEX SHOX SHOX HOXC5 HOXC5 ARX ARX POU6F2 POU6F2 PAX6 PAX6 CERS2 CERS2 HOXA10 HOXA10 HOXC8 HOXC8 PITX1 PITX1 LHX3 LHX3 LMX1B LMX1B SIX4 SIX4 NKX3-2 NKX3-2 SIX3 SIX3 MEIS2 MEIS2 LHX2 LHX2 DLX1 DLX1 DLX4 DLX4 ALX4 ALX4 PRRX1 PRRX1 PBX3 PBX3 HOXC4 HOXC4 NKX2-6 NKX2-6 VENTX VENTX DRGX DRGX MEIS1 MEIS1 TGIF2 TGIF2 NKX1-1 NKX1-1 NKX2-5 NKX2-5 EMX2 EMX2 IRX1 IRX1 BARX2 BARX2 DLX5 DLX5 ZHX3 ZHX3 SIX5 SIX5 HDX HDX LOC100153205 LOC100153205 NKX6-3 NKX6-3 OTX1 OTX1 PKNOX1 PKNOX1 EN2 EN2 HOXC9 HOXC9 GBX1 GBX1 PITX2 PITX2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ALX1ALX homeobox 1. (326 aa)
POU6F1POU domain protein. (615 aa)
HOXC13Homeobox C13. (332 aa)
HOXC12Homeobox C12. (282 aa)
POU5F1POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. Belongs to the POU transcription factor family. Class-5 subfamily. (361 aa)
NKX2-8NK2 homeobox 8. (241 aa)
VSX2Visual system homeobox 2. (361 aa)
GSCGoosecoid homeobox. (256 aa)
ZFHX3Zinc finger homeobox 3. (3722 aa)
IRX6Iroquois homeobox 6. (410 aa)
IRX3Iroquois-class homeodomain protein IRX-3 isoform X2. (502 aa)
MEIS3Meis homeobox 3. (376 aa)
POU3F1POU domain protein. (451 aa)
DMBX1Diencephalon/mesencephalon homeobox 1. (379 aa)
ONECUT2One cut domain family member. (694 aa)
CERS3Ceramide synthase 3. (385 aa)
RAXRetina and anterior neural fold homeobox. (346 aa)
OTX2Orthodenticle homeobox 2. (297 aa)
SIX6Homeobox protein SIX6. (246 aa)
SIX1Six homeobox 1. (284 aa)
PRRX2Paired related homeobox 2. (255 aa)
BARHL1BarH like homeobox 1. (327 aa)
ZHX1Zinc fingers and homeoboxes protein 1. (872 aa)
BARHL2BarH like homeobox 2. (384 aa)
NKX2-4NK2 homeobox 4. (356 aa)
BARX1Homeobox protein BarH-like 1. (254 aa)
LBX2Ladybird homeobox 2. (196 aa)
EMX1Empty spiracles homeobox 1. (288 aa)
VAX2Ventral anterior homeobox 2. (288 aa)
SIX2SIX homeobox 2. (296 aa)
HMX1H6 family homeobox 1. (350 aa)
MSX1Homeobox domain-containing protein. (303 aa)
GSX2GS homeobox 2. (304 aa)
NKX6-1NK6 homeobox 1. (370 aa)
GSX1GS homeobox 1. (267 aa)
CDX2Homeobox domain-containing protein. (310 aa)
HMBOX1Homeobox-containing protein 1 isoform 1. (420 aa)
CUX2Homeobox protein cut-like. (1490 aa)
LHX5LIM/homeobox protein Lhx5. (402 aa)
HNF1AHepatocyte nuclear factor 1-alpha isoform 2. (631 aa)
GSC2Goosecoid homeobox 2. (205 aa)
NKX2-3NK2 homeobox 3. (367 aa)
PITX3Homeobox protein. (298 aa)
VAX1Ventral anterior homeobox 1. (333 aa)
HMX2H6 family homeobox 2. (281 aa)
NKX1-2NK1 homeobox 2. (315 aa)
SATB1DNA-binding protein SATB. (751 aa)
POU1F1Pituitary-specific positive transcription factor 1; Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'-TAAAT-3'. (317 aa)
POU3F4POU domain protein. (352 aa)
DBX1Developing brain homeobox 1. (343 aa)
ONECUT3One cut domain family member. (492 aa)
CERS4Ceramide synthase 4. (393 aa)
OTPOrthopedia homeobox. (325 aa)
POU4F3POU domain protein. (338 aa)
PHOX2APaired mesoderm homeobox protein 2A. (286 aa)
BSXBrain specific homeobox. (232 aa)
MEOX2Homeobox domain-containing protein. (303 aa)
LHX4LIM homeobox 4. (390 aa)
EN1Homeobox protein engrailed-like. (367 aa)
DLX2Distal-less homeobox 2. (328 aa)
HOXD13Homeobox protein Hox-D13. (341 aa)
HOXD12Homeobox protein Hox-D12. (270 aa)
HOXD10Homeobox protein Hox-D10. (410 aa)
HOXD9Homeobox D9. (351 aa)
HOXD4Homeobox protein Hox-D4. (257 aa)
HOXD3Homeobox protein Hox-D3. (432 aa)
HOXD1Homeobox D1. (327 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
MNX1Motor neuron and pancreas homeobox 1. (401 aa)
EVX1Even-skipped homeobox 1. (407 aa)
HOXA11Homeobox protein Hox-A11. (317 aa)
HOXA5Homeobox domain-containing protein. (381 aa)
HOXA4Homeobox domain-containing protein. (329 aa)
CDX4Caudal type homeobox 4. (284 aa)
POU4F2POU domain protein. (408 aa)
POU2F3POU domain protein. (436 aa)
TSHZ3Teashirt zinc finger homeobox 3. (1010 aa)
SHOX2Short stature homeobox 2. (321 aa)
TLX2T cell leukemia homeobox 2. (283 aa)
PAX3Paired box protein Pax-3 isoform PAX3e. (484 aa)
HOXA9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (272 aa)
PBX4PBX homeobox 4. (377 aa)
LBX1Ladybird homeobox 1. (281 aa)
PROP1Homeobox protein prophet of Pit-1; Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes. (226 aa)
VSX1Visual system homeobox 1. (364 aa)
EVX2Even-skipped homeobox 2. (474 aa)
HOMEZHomeobox and leucine zipper encoding. (639 aa)
PKNOX2PBX/knotted 1 homeobox 2. (472 aa)
HOXA7Homeobox A7. (234 aa)
TGIF1TGFB induced factor homeobox 1. (273 aa)
HOXA3Homeobox protein Hox-A3 isoform a. (443 aa)
HOXA2Homeobox protein Hox-A2. (380 aa)
DLX3Distal-less homeobox 3. (287 aa)
HOXB13Homeobox B13. (285 aa)
HOXB5Homeobox protein Hox-B5. (269 aa)
HOXB6Homeobox protein Hox-B6 isoform X1. (224 aa)
HOXB7Homeobox protein Hox-B7. (217 aa)
HOXB8Homeobox protein Hox-B8; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. (242 aa)
HOXB4Homeobox B4. (278 aa)
HOXB3Homeobox B3. (430 aa)
HOXB2Homeobox protein Hox-B2. (353 aa)
HOXB1Homeobox protein Hox-B1. (301 aa)
MEOX1Homeobox protein MOX-1 isoform X1. (254 aa)
IRX4Iroquois-class homeodomain protein IRX-4 isoform b. (515 aa)
TLX3T cell leukemia homeobox 3. (338 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
HOXA1Homeobox protein Hox-A1 isoform X1. (336 aa)
CRXCone-rod homeobox. (345 aa)
HLXH2.0 like homeobox. (556 aa)
ZHX2Zinc fingers and homeoboxes 2. (827 aa)
PAX4Paired box 4. (345 aa)
HOPXHomeodomain-only protein; Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF- dependent cardiac-specific genes and cardiac development. Prevents SRF- dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein ref [...] (285 aa)
HNF1BHepatocyte nuclear factor 1-beta; Transcription factor, probably binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Binds to the PFC element in the UPA gene. (577 aa)
A0A5G2QU24_PIGHomeobox domain-containing protein. (317 aa)
DPRXDivergent-paired related homeobox. (196 aa)
CUX1Homeobox protein cut-like. (1642 aa)
LOC102157657Homeobox domain-containing protein. (183 aa)
LHX6LIM homeobox 6. (392 aa)
ADNP2ADNP homeobox 2. (1197 aa)
PAX7Paired box 7. (521 aa)
POU2F2POU domain, class 2, transcription factor 2; Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR (By similarity). Belongs to the POU transcription factor family. Class-2 subfamily. (711 aa)
HOXC6Homeobox protein Hox-C6 isoform 1. (235 aa)
SMYD5SET and MYND domain-containing protein 5 isoform X1. (596 aa)
PHOX2BPaired like homeobox 2B. (314 aa)
NKX6-2Homeobox protein Nkx-6.2. (277 aa)
POU2F1POU domain, class 2, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR (By similarity); Belongs to the POU transcription factor family. Class-2 subfamily. (836 aa)
NKX3-1Homeobox protein Nkx-3.1 isoform 1. (247 aa)
LMX1ALIM homeobox transcription factor 1 alpha. (382 aa)
NANOGHomeobox domain-containing protein. (304 aa)
ZFHX4Zinc finger homeobox 4. (3585 aa)
TLX1T cell leukemia homeobox 1. (334 aa)
HOXD8Homeobox D8. (291 aa)
HOXB9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (250 aa)
NKX2-1NK2 homeobox 1. (399 aa)
IRX2Iroquois-class homeodomain protein IRX-2. (473 aa)
ISL2ISL LIM homeobox 2. (359 aa)
NKX2-2Homeobox protein Nkx-2.2. (273 aa)
MSX2Homeobox protein MSX-2. (267 aa)
HOXD11Homeobox D11. (336 aa)
HMX3H6 family homeobox 3. (357 aa)
POU4F1POU domain protein. (421 aa)
CERS6Ceramide synthase 6. (392 aa)
PDX1Homeobox domain-containing protein. (284 aa)
ISXIntestine specific homeobox. (249 aa)
HESX1HESX homeobox 1. (185 aa)
HOXC11Homeobox C11. (304 aa)
CERS5Ceramide synthase 5 isoform X1. (392 aa)
POU3F3POU domain, class 3, transcription factor 3; Transcription factor that acts synergistically with SOX11 and SOX4. Plays a role in neuronal development. Is implicated in an enhancer activity at the embryonic met-mesencephalic junction; the enhancer element contains the octamer motif (5'-ATTTGCAT-3') (By similarity); Belongs to the POU transcription factor family. Class-3 subfamily. (501 aa)
MIXL1Mix paired-like homeobox. (237 aa)
HOXA13Homeobox A13. (388 aa)
SATB2DNA-binding protein SATB. (733 aa)
HOXC10Homeobox C10. (342 aa)
SEBOXSEBOX homeobox. (192 aa)
NOBOXHomeobox domain-containing protein. (472 aa)
MKXMohawk homeobox. (351 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1128 aa)
RAX2Retina and anterior neural fold homeobox protein 2 isoform 2. (184 aa)
ZFHX2Zinc finger homeobox 2. (2565 aa)
PBX2Homeobox domain-containing protein. (429 aa)
IRX5Iroquois homeobox 5. (483 aa)
HHEXHematopoietically-expressed homeobox protein HHEX. (269 aa)
SHOXUncharacterized protein. (292 aa)
HOXC5Homeobox C5. (222 aa)
ARXAristaless related homeobox. (563 aa)
POU6F2POU domain protein. (678 aa)
PAX6Paired box 6. (498 aa)
CERS2Ceramide synthase 2 isoform X1. (524 aa)
HOXA10Homeobox protein Hox-A10. (411 aa)
HOXC8Homeobox C8. (242 aa)
PITX1Homeobox protein. (314 aa)
LHX3LIM/homeobox protein Lhx3; Required for the establishment of the specialized cells of the pituitary gland and the nervous system. Involved in the development of interneurons and motor neurons in cooperation with LDB1 and ISL1. Acts as a transcriptional activator. Binds to and activates the promoter of the alpha-glycoprotein gene, and synergistically enhances transcription from the prolactin promoter in cooperation with POU1F1/Pit-1 (By similarity). (538 aa)
LMX1BLIM homeobox transcription factor 1 beta. (395 aa)
SIX4Homeobox domain-containing protein. (785 aa)
NKX3-2NK3 homeobox 2. (337 aa)
SIX3SIX homeobox 3. (333 aa)
MEIS2Meis homeobox 2. (477 aa)
LHX2LIM/homeobox protein Lhx2. (406 aa)
DLX1Homeobox protein DLX-1 isoform 1. (255 aa)
DLX4Distal-less homeobox 4. (233 aa)
ALX4ALX homeobox 4. (406 aa)
PRRX1Paired mesoderm homeobox protein 1 isoform pmx-1b. (245 aa)
PBX3PBX homeobox 3. (454 aa)
HOXC4Homeobox protein Hox-C4. (264 aa)
NKX2-6NK2 homeobox 6. (299 aa)
VENTXUncharacterized protein. (212 aa)
DRGXDorsal root ganglia homeobox. (263 aa)
MEIS1Homeobox protein Meis1. (465 aa)
TGIF2TGFB induced factor homeobox 2. (237 aa)
NKX1-1NK1 homeobox 1. (403 aa)
NKX2-5NK2 homeobox 5. (323 aa)
EMX2Empty spiracles homeobox 2. (252 aa)
IRX1Iroquois homeobox 1. (478 aa)
BARX2BARX homeobox 2. (278 aa)
DLX5Homeobox protein DLX-5. (290 aa)
ZHX3Zinc fingers and homeoboxes protein 3 isoform X3. (954 aa)
SIX5Homeobox protein SIX5. (737 aa)
HDXHighly divergent homeobox. (677 aa)
LOC100153205Homeobox domain-containing protein. (375 aa)
NKX6-3Homeobox protein Nkx-6.3 isoform X1. (261 aa)
OTX1Orthodenticle homeobox 1. (356 aa)
PKNOX1PBX/knotted 1 homeobox 1. (435 aa)
EN2Homeobox protein engrailed-like. (342 aa)
HOXC9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (260 aa)
GBX1Gastrulation brain homeobox 1. (365 aa)
PITX2Homeobox protein. (326 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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