43 items (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ADAMTS8	ADAM metallopeptidase with thrombospondin type 1 motif 8. (1019 aa)
	ADAMTS1	Peptidase M12B domain-containing protein. (963 aa)
	ADAM10	Disintegrin and metalloproteinase domain-containing protein 10; Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2, CD44, CDH2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP). Contributes to the normal cleavage of the cellular prion protein. Involved in the cleavage of the adhesion [...] (748 aa)
	ADAM28	ADAM metallopeptidase domain 28. (795 aa)
	ADAM23	ADAM metallopeptidase domain 23. (833 aa)
	ADAMTS18	ADAM metallopeptidase with thrombospondin type 1 motif 18. (1223 aa)
	LOC110258345	Uncharacterized protein. (718 aa)
	A0A287BNZ6_PIG	Uncharacterized protein. (623 aa)
	A0A287BJG7_PIG	Uncharacterized protein. (739 aa)
	ADAM22	Disintegrin and metalloproteinase domain-containing protein 22 isoform X7. (970 aa)
	ADAM33	ADAM metallopeptidase domain 33. (790 aa)
	A0A287AJR1_PIG	Uncharacterized protein. (737 aa)
	A0A287AE08_PIG	Uncharacterized protein. (847 aa)
	ADAM20	ADAM metallopeptidase domain 20. (737 aa)
	ADAMTS10	Uncharacterized protein. (1102 aa)
	ADAM7	ADAM metallopeptidase domain 7. (774 aa)
	ADAM8	Disintegrin and metalloproteinase domain-containing protein 8. (835 aa)
	ADAMTS12	ADAM metallopeptidase with thrombospondin type 1 motif 12. (1598 aa)
	ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif 2. (1204 aa)
	ADAM29	Uncharacterized protein. (721 aa)
	ADAMTS16	ADAM metallopeptidase with thrombospondin type 1 motif 16. (1202 aa)
	ADAM19	ADAM metallopeptidase domain 19. (951 aa)
	ADAMTS6	A disintegrin and metalloproteinase with thrombospondin motifs 6 isoform X1. (1117 aa)
	ADAM9	Disintegrin and metalloproteinase domain-containing protein 9 isoform X1. (819 aa)
	F1RZL6_PIG	Uncharacterized protein. (718 aa)
	ADAM2	Fertilin beta. (735 aa)
	LOC100049687	Uncharacterized protein. (758 aa)
	ADAMTS15	A disintegrin and metalloproteinase with thrombospondin motifs 15 preproprotein. (950 aa)
	ADAMTS19	ADAM metallopeptidase with thrombospondin type 1 motif 19. (1206 aa)
	ADAMTS5	ADAM metallopeptidase with thrombospondin type 1 motif 5. (929 aa)
	ADAMTS9	ADAM metallopeptidase with thrombospondin type 1 motif 9. (2020 aa)
	ADAMTS14	ADAM metallopeptidase with thrombospondin type 1 motif 14. (1320 aa)
	F1RJK7_PIG	Uncharacterized protein. (760 aa)
	F1RJL7_PIG	Uncharacterized protein. (767 aa)
	ADAM17	Disintegrin and metalloproteinase domain-containing protein 17; Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membra [...] (822 aa)
	ADAM18	ADAM metallopeptidase domain 18. (737 aa)
	ADAM30	ADAM metallopeptidase domain 30. (727 aa)
	ADAM15	Disintegrin and metalloproteinase domain-containing protein 15 isoform 6 preproprotein. (866 aa)
	ADAMTS4	ADAM metallopeptidase with thrombospondin type 1 motif 4. (872 aa)
	ADAM21	ADAM metallopeptidase domain 21. (735 aa)
	LOC100525409	Uncharacterized protein. (745 aa)
	ADAMTS7	ADAM metallopeptidase with thrombospondin type 1 motif 7. (1660 aa)
	ADAMTS20	ADAM metallopeptidase with thrombospondin type 1 motif 20. (1915 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM10	ADAM15	ENSSSCP00000067539	ENSSSCP00000006962	Disintegrin and metalloproteinase domain-containing protein 10; Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2, CD44, CDH2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP). Contributes to the normal cleavage of the cellular prion protein. Involved in the cleavage of the adhesion [...]	Disintegrin and metalloproteinase domain-containing protein 15 isoform 6 preproprotein.	0.425
ADAM10	ADAM17	ENSSSCP00000067539	ENSSSCP00000009208	Disintegrin and metalloproteinase domain-containing protein 10; Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2, CD44, CDH2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP). Contributes to the normal cleavage of the cellular prion protein. Involved in the cleavage of the adhesion [...]	Disintegrin and metalloproteinase domain-containing protein 17; Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membra [...]	0.943
ADAM15	ADAM10	ENSSSCP00000006962	ENSSSCP00000067539	Disintegrin and metalloproteinase domain-containing protein 15 isoform 6 preproprotein.	Disintegrin and metalloproteinase domain-containing protein 10; Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2, CD44, CDH2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP). Contributes to the normal cleavage of the cellular prion protein. Involved in the cleavage of the adhesion [...]	0.425
ADAM17	ADAM10	ENSSSCP00000009208	ENSSSCP00000067539	Disintegrin and metalloproteinase domain-containing protein 17; Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membra [...]	Disintegrin and metalloproteinase domain-containing protein 10; Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2, CD44, CDH2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP). Contributes to the normal cleavage of the cellular prion protein. Involved in the cleavage of the adhesion [...]	0.943
ADAM17	ADAM9	ENSSSCP00000009208	ENSSSCP00000016755	Disintegrin and metalloproteinase domain-containing protein 17; Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membra [...]	Disintegrin and metalloproteinase domain-containing protein 9 isoform X1.	0.489
ADAM2	ADAM20	ENSSSCP00000016751	ENSSSCP00000036851	Fertilin beta.	ADAM metallopeptidase domain 20.	0.858
ADAM2	ADAM21	ENSSSCP00000016751	ENSSSCP00000002520	Fertilin beta.	ADAM metallopeptidase domain 21.	0.843
ADAM2	ADAM30	ENSSSCP00000016751	ENSSSCP00000007159	Fertilin beta.	ADAM metallopeptidase domain 30.	0.822
ADAM2	ADAMTS14	ENSSSCP00000016751	ENSSSCP00000010951	Fertilin beta.	ADAM metallopeptidase with thrombospondin type 1 motif 14.	0.538
ADAM20	ADAM2	ENSSSCP00000036851	ENSSSCP00000016751	ADAM metallopeptidase domain 20.	Fertilin beta.	0.858
ADAM20	ADAM21	ENSSSCP00000036851	ENSSSCP00000002520	ADAM metallopeptidase domain 20.	ADAM metallopeptidase domain 21.	0.804
ADAM20	ADAM30	ENSSSCP00000036851	ENSSSCP00000007159	ADAM metallopeptidase domain 20.	ADAM metallopeptidase domain 30.	0.812
ADAM21	ADAM2	ENSSSCP00000002520	ENSSSCP00000016751	ADAM metallopeptidase domain 21.	Fertilin beta.	0.843
ADAM21	ADAM20	ENSSSCP00000002520	ENSSSCP00000036851	ADAM metallopeptidase domain 21.	ADAM metallopeptidase domain 20.	0.804
ADAM21	ADAM30	ENSSSCP00000002520	ENSSSCP00000007159	ADAM metallopeptidase domain 21.	ADAM metallopeptidase domain 30.	0.809
ADAM22	ADAM23	ENSSSCP00000055543	ENSSSCP00000062593	Disintegrin and metalloproteinase domain-containing protein 22 isoform X7.	ADAM metallopeptidase domain 23.	0.671
ADAM23	ADAM22	ENSSSCP00000062593	ENSSSCP00000055543	ADAM metallopeptidase domain 23.	Disintegrin and metalloproteinase domain-containing protein 22 isoform X7.	0.671
ADAM30	ADAM2	ENSSSCP00000007159	ENSSSCP00000016751	ADAM metallopeptidase domain 30.	Fertilin beta.	0.822
ADAM30	ADAM20	ENSSSCP00000007159	ENSSSCP00000036851	ADAM metallopeptidase domain 30.	ADAM metallopeptidase domain 20.	0.812
ADAM30	ADAM21	ENSSSCP00000007159	ENSSSCP00000002520	ADAM metallopeptidase domain 30.	ADAM metallopeptidase domain 21.	0.809