STRINGSTRING
RASD1 RASD1 RAB27A RAB27A AGAP3 AGAP3 RABL2B RABL2B RASD2 RASD2 NKIRAS1 NKIRAS1 RAB39A RAB39A RHOQ RHOQ RHOH RHOH RALB RALB RAB15 RAB15 RRAS2 RRAS2 RHOT1 RHOT1 A0A287A0E5_PIG A0A287A0E5_PIG RAB11A RAB11A RAP1B RAP1B RAP2A RAP2A RAB23 RAB23 RASL12 RASL12 RAB27B RAB27B RAB5A RAB5A RASL11A RASL11A RAB43 RAB43 RAB7A RAB7A RAB30 RAB30 RAB12 RAB12 CDC42 CDC42 RAB9A RAB9A RHOJ RHOJ RND2 RND2 F1RSX1_PIG F1RSX1_PIG RAB42 RAB42 RHOD RHOD RAB33B RAB33B RAB29 RAB29 RAP2C RAP2C RAB28 RAB28 KRAS KRAS RAB20 RAB20 RAB18 RAB18 RAB39B RAB39B RHOU RHOU NKIRAS2 NKIRAS2 RAB3A RAB3A RAB8A RAB8A RAB11B RAB11B RASL10A RASL10A RHOF RHOF RASL11B RASL11B DNAJC27 DNAJC27 RHOC RHOC RAB13 RAB13 RAP2B RAP2B RAB14 RAB14 RAB40C RAB40C RAB3D RAB3D RAB9B RAB9B RAB38 RAB38 RRAD RRAD AGAP2 AGAP2 RIT1 RIT1 RAB2A RAB2A RHOV RHOV CPLANE2 CPLANE2 RRAS RRAS ARHGAP35 ARHGAP35 RAB4B RAB4B RAB44 RAB44 RERG RERG RHEBL1 RHEBL1 IFT27 IFT27 RAB25 RAB25 RND1 RND1 RHEB RHEB RAB35 RAB35 RERGL RERGL RHOG RHOG RND3 RND3 HRAS HRAS RAP1A RAP1A RAB26 RAB26 AGAP1 AGAP1 RAB8B RAB8B RAC3 RAC3 A0A287ARP2_PIG A0A287ARP2_PIG NRAS NRAS RHOA RHOA RAB6A RAB6A DIRAS1 DIRAS1 RHOBTB1 RHOBTB1 RAB7B RAB7B RASL10B RASL10B RASEF RASEF RAB4A RAB4A RAB5C RAB5C DIRAS2 DIRAS2 RAB37 RAB37 RAN RAN RAC2 RAC2 REM1 REM1 RAB3B RAB3B RAB40B RAB40B RHOB RHOB EGLN2-2 EGLN2-2 RAB3C RAB3C DIRAS3 DIRAS3 RAB24 RAB24 RAB19 RAB19 RAB31 RAB31 RAC1 RAC1 MRAS MRAS RALA RALA RAB2B RAB2B RAB10 RAB10 RAB1A RAB1A RAB34 RAB34 RAB22A RAB22A LOC102158400 LOC102158400
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RASD1Ras related dexamethasone induced 1. (276 aa)
RAB27ARas-related protein Rab-27A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion. Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. (221 aa)
AGAP3ArfGAP with GTPase domain, ankyrin repeat and PH domain 3. (1025 aa)
RABL2BRab-like protein 2A isoform X5. (232 aa)
RASD2RASD family member 2. (303 aa)
NKIRAS1NF-kappa-B inhibitor-interacting Ras-like protein 1 isoform X1. (192 aa)
RAB39ARAB39A, member RAS oncogene family. (217 aa)
RHOQRho-related GTP-binding protein RhoQ. (205 aa)
RHOHRho-related GTP-binding protein RhoH. (191 aa)
RALBRAS like proto-oncogene B. (206 aa)
RAB15RAB15, member RAS oncogene family. (197 aa)
RRAS2Uncharacterized protein. (276 aa)
RHOT1Ras homolog family member T1. (752 aa)
A0A287A0E5_PIGUncharacterized protein. (151 aa)
RAB11ARas-related protein Rab-11A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The small Rab GTPase RAB11A regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial c [...] (216 aa)
RAP1BRAP1B, member of RAS oncogene family. (184 aa)
RAP2ARas-related protein Rap-2a. (183 aa)
RAB23RAB23, member RAS oncogene family. (206 aa)
RASL12RAS like family 12. (266 aa)
RAB27BRAB27B, member RAS oncogene family. (247 aa)
RAB5ARas-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...] (215 aa)
RASL11ARAS like family 11 member A. (242 aa)
RAB43RAB43, member RAS oncogene family. (210 aa)
RAB7ARAB7A, member RAS oncogene family. (252 aa)
RAB30RAB30, member RAS oncogene family. (203 aa)
RAB12RAB12, member RAS oncogene family. (332 aa)
CDC42Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] (197 aa)
RAB9ARAB9A, member RAS oncogene family. (201 aa)
RHOJUncharacterized protein. (213 aa)
RND2Rho family GTPase 2. (231 aa)
F1RSX1_PIGUncharacterized protein. (200 aa)
RAB42Ras-related protein Rab-42 isoform 1. (219 aa)
RHODRas homolog family member D. (203 aa)
RAB33BRAB33B, member RAS oncogene family. (229 aa)
RAB29RAB29, member RAS oncogene family. (221 aa)
RAP2CRAP2C, member of RAS oncogene family. (183 aa)
RAB28RAB28, member RAS oncogene family. (252 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
RAB20RAB20, member RAS oncogene family. (233 aa)
RAB18RAB18, member RAS oncogene family. (206 aa)
RAB39BRAB39B, member RAS oncogene family. (213 aa)
RHOURas homolog family member U. (258 aa)
NKIRAS2NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform a. (191 aa)
RAB3ARas-related protein Rab-3A; Small GTP-binding protein that plays a central role in regulated exocytosis and secretion. Controls the recruitment, tethering and docking of secretory vesicles to the plasma membrane (By similarity). Upon stimulation, switches to its active GTP-bound form, cycles to vesicles and recruits effectors such as RIMS1, RIMS2, Rabphilin-3A/RPH3A, RPH3AL or SYTL4 to help the docking of vesicules onto the plasma membrane (By similarity). Upon GTP hydrolysis by GTPase-activating protein, dissociates from the vesicle membrane allowing the exocytosis to proceed (By simi [...] (254 aa)
RAB8AUncharacterized protein. (242 aa)
RAB11BUncharacterized protein. (205 aa)
RASL10ARas-like protein family member 10A. (203 aa)
RHOFRas homolog family member F, filopodia associated. (249 aa)
RASL11BRAS like family 11 member B. (248 aa)
DNAJC27DnaJ heat shock protein family (Hsp40) member C27. (273 aa)
RHOCRas homolog family member C. (202 aa)
RAB13Uncharacterized protein. (203 aa)
RAP2BRas-related protein Rap-2a; Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading (By similarity). (183 aa)
RAB14Ras-related protein Rab-14; Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes. Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N- cadherin/CDH2 shedding and cell [...] (197 aa)
RAB40CRas-related protein Rab-40C isoform a. (281 aa)
RAB3DRAB3D, member RAS oncogene family. (218 aa)
RAB9BRAB9B, member RAS oncogene family. (201 aa)
RAB38Ras-related protein Rab-32; Acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and Mycobacterium. Plays an important role in the control of melanin production and melanosome biogenesis. In concert with RAB38, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes. Belongs to the small GTPase superfam [...] (211 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
AGAP2ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1201 aa)
RIT1Ras like without CAAX 1. (219 aa)
RAB2ARAB2A, member RAS oncogene family. (226 aa)
RHOVUncharacterized protein. (236 aa)
CPLANE2Ciliogenesis and planar polarity effector 2. (258 aa)
RRASRAS related. (218 aa)
ARHGAP35Rho GTPase-activating protein 35. (1500 aa)
RAB4BUncharacterized protein. (228 aa)
RAB44RAB44, member RAS oncogene family. (984 aa)
RERGRAS like estrogen regulated growth inhibitor. (180 aa)
RHEBL1RHEB like 1. (183 aa)
IFT27Intraflagellar transport 27. (189 aa)
RAB25RAB25, member RAS oncogene family. (213 aa)
RND1Rho family GTPase 1. (244 aa)
RHEBUncharacterized protein. (220 aa)
RAB35Uncharacterized protein. (233 aa)
RERGLRas-related and estrogen-regulated growth inhibitor-like protein isoform b. (204 aa)
RHOGUncharacterized protein. (394 aa)
RND3Rho-related GTP-binding protein RhoE; Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins. (244 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
RAB26RAB26, member RAS oncogene family. (249 aa)
AGAP1ArfGAP with GTPase domain, ankyrin repeat and PH domain 1. (1156 aa)
RAB8BRAB8B, member RAS oncogene family. (215 aa)
RAC3Rac family small GTPase 3. (192 aa)
A0A287ARP2_PIGUncharacterized protein. (192 aa)
NRASGTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (189 aa)
RHOATransforming protein RhoA isoform 1. (193 aa)
RAB6ARAB6A, member RAS oncogene family. (254 aa)
DIRAS1DIRAS family GTPase 1. (352 aa)
RHOBTB1Rho-related BTB domain-containing protein 1 isoform 1. (698 aa)
RAB7BRAB7B, member RAS oncogene family. (200 aa)
RASL10BRAS like family 10 member B. (203 aa)
RASEFEF-hand domain-containing protein. (684 aa)
RAB4ARAB4A, member RAS oncogene family. (223 aa)
RAB5CUncharacterized protein. (227 aa)
DIRAS2GTP-binding protein Di-Ras2. (199 aa)
RAB37RAB37, member RAS oncogene family. (294 aa)
RANGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (222 aa)
RAC2Rac family small GTPase 2. (217 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (314 aa)
RAB3BRAB3B, member RAS oncogene family. (249 aa)
RAB40BRAB40B, member RAS oncogene family. (453 aa)
RHOBRho-related GTP-binding protein RhoB. (196 aa)
EGLN2-2Fe2OG dioxygenase domain-containing protein. (125 aa)
RAB3CRAB3C, member RAS oncogene family. (235 aa)
DIRAS3GTP-binding RAS-like protein 3. (228 aa)
RAB24Uncharacterized protein. (294 aa)
RAB19RAB19, member RAS oncogene family. (246 aa)
RAB31RAB31, member RAS oncogene family. (195 aa)
RAC1Rac family small GTPase 1. (186 aa)
MRASMuscle RAS oncogene homolog. (210 aa)
RALARas-related protein Ral-A isoform X1. (206 aa)
RAB2BUncharacterized protein. (226 aa)
RAB10Uncharacterized protein. (201 aa)
RAB1ARas-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] (217 aa)
RAB34Ras-related protein Rab-34; Protein transport. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and Mycobacterium. Plays a role in the fusion of phagosomes with lysosomes. Involved in the redistribution of lysosomes to the peri-Golgi region. Acts also as a positive regulator of hedgehog signaling and regulates ciliary function. (260 aa)
RAB22AUncharacterized protein. (256 aa)
LOC102158400Uncharacterized protein. (71 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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