(5 nodes) Phosphatidylinositol-4-phosphate 5-kinase, core network (Sus scrofa)

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Your Input:
	PIP5KL1	Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 isoform 1. (396 aa)
	PIP4K2B	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta. (416 aa)
	PIKFYVE	Phosphoinositide kinase, FYVE-type zinc finger containing. (2055 aa)
	PIP5K1C	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X5. (702 aa)
	PIP4K2A	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha; Catalyzes the phosphorylation of phosphatidylinositol 5- phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation. May negatively regulate insulin-stimulated glucose uptake by lowering the levels of [...] (442 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PIKFYVE	PIP4K2A	ENSSSCP00000054023	ENSSSCP00000011818	Phosphoinositide kinase, FYVE-type zinc finger containing.	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha; Catalyzes the phosphorylation of phosphatidylinositol 5- phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation. May negatively regulate insulin-stimulated glucose uptake by lowering the levels of [...]	0.916
PIKFYVE	PIP4K2B	ENSSSCP00000054023	ENSSSCP00000073414	Phosphoinositide kinase, FYVE-type zinc finger containing.	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta.	0.916
PIP4K2A	PIKFYVE	ENSSSCP00000011818	ENSSSCP00000054023	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha; Catalyzes the phosphorylation of phosphatidylinositol 5- phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation. May negatively regulate insulin-stimulated glucose uptake by lowering the levels of [...]	Phosphoinositide kinase, FYVE-type zinc finger containing.	0.916
PIP4K2A	PIP4K2B	ENSSSCP00000011818	ENSSSCP00000073414	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha; Catalyzes the phosphorylation of phosphatidylinositol 5- phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation. May negatively regulate insulin-stimulated glucose uptake by lowering the levels of [...]	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta.	0.942
PIP4K2A	PIP5K1C	ENSSSCP00000011818	ENSSSCP00000047631	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha; Catalyzes the phosphorylation of phosphatidylinositol 5- phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation. May negatively regulate insulin-stimulated glucose uptake by lowering the levels of [...]	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X5.	0.906
PIP4K2A	PIP5KL1	ENSSSCP00000011818	ENSSSCP00000006031	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha; Catalyzes the phosphorylation of phosphatidylinositol 5- phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation. May negatively regulate insulin-stimulated glucose uptake by lowering the levels of [...]	Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 isoform 1.	0.904
PIP4K2B	PIKFYVE	ENSSSCP00000073414	ENSSSCP00000054023	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta.	Phosphoinositide kinase, FYVE-type zinc finger containing.	0.916
PIP4K2B	PIP4K2A	ENSSSCP00000073414	ENSSSCP00000011818	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta.	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha; Catalyzes the phosphorylation of phosphatidylinositol 5- phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation. May negatively regulate insulin-stimulated glucose uptake by lowering the levels of [...]	0.942
PIP4K2B	PIP5K1C	ENSSSCP00000073414	ENSSSCP00000047631	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta.	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X5.	0.911
PIP4K2B	PIP5KL1	ENSSSCP00000073414	ENSSSCP00000006031	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta.	Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 isoform 1.	0.900
PIP5K1C	PIP4K2A	ENSSSCP00000047631	ENSSSCP00000011818	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X5.	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha; Catalyzes the phosphorylation of phosphatidylinositol 5- phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation. May negatively regulate insulin-stimulated glucose uptake by lowering the levels of [...]	0.906
PIP5K1C	PIP4K2B	ENSSSCP00000047631	ENSSSCP00000073414	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X5.	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta.	0.911
PIP5K1C	PIP5KL1	ENSSSCP00000047631	ENSSSCP00000006031	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X5.	Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 isoform 1.	0.913
PIP5KL1	PIP4K2A	ENSSSCP00000006031	ENSSSCP00000011818	Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 isoform 1.	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha; Catalyzes the phosphorylation of phosphatidylinositol 5- phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation. May negatively regulate insulin-stimulated glucose uptake by lowering the levels of [...]	0.904
PIP5KL1	PIP4K2B	ENSSSCP00000006031	ENSSSCP00000073414	Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 isoform 1.	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta.	0.900
PIP5KL1	PIP5K1C	ENSSSCP00000006031	ENSSSCP00000047631	Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 isoform 1.	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X5.	0.913