STRINGSTRING
LINGO3 LINGO3 IGSF11 IGSF11 CD3G CD3G FGFR3 FGFR3 FGFRL1 FGFRL1 VSIG4 VSIG4 ALPK3 ALPK3 ADAMTSL1 ADAMTSL1 NPTN NPTN NTRK2 NTRK2 KAZALD1 KAZALD1 SPEGNB SPEGNB CEACAM21 CEACAM21 NPHS1 NPHS1 SIGLEC1 SIGLEC1 LRRC4B LRRC4B ISLR2 ISLR2 SPEG SPEG A0A286ZV66_PIG A0A286ZV66_PIG CNTN6 CNTN6 WFIKKN1 WFIKKN1 CXADR CXADR NEO1 NEO1 CADM3 CADM3 FCRL3 FCRL3 LRIT1 LRIT1 A0A286ZNZ8_PIG A0A286ZNZ8_PIG UNC5C UNC5C MYOM2 MYOM2 VSIG10 VSIG10 JAM2 JAM2 UNC5B UNC5B PTPRF PTPRF A0A286ZIE2_PIG A0A286ZIE2_PIG LOC100521529 LOC100521529 FGFR2 FGFR2 FGFR1 FGFR1 MALT1 MALT1 CEACAM16 CEACAM16 NCAM1 NCAM1 SIRPB2 SIRPB2 KDR KDR FCER1A FCER1A IGFN1 IGFN1 LOC100513863 LOC100513863 GP6 GP6 HEPACAM2 HEPACAM2 MYBPH MYBPH CDON CDON PTPRS PTPRS LSAMP LSAMP CEACAM20 CEACAM20 ROBO2 ROBO2 PXDN PXDN FCRLA FCRLA CEACAM1 CEACAM1 LINGO4 LINGO4 FCRL5 FCRL5 FSTL5 FSTL5 WFIKKN2 WFIKKN2 TRIO TRIO LRRN3 LRRN3 LRRC4 LRRC4 CCDC141 CCDC141 KIRREL3 KIRREL3 ROBO4 ROBO4 ROBO3 ROBO3 ESAM ESAM VSIG2 VSIG2 NECTIN1 NECTIN1 CD3E CD3E PDGFRB PDGFRB FSTL4 FSTL4 FLT4 FLT4 CILP2 CILP2 ICAM5 ICAM5 CD22 CD22 IL1RAPL1 IL1RAPL1 DSCAM DSCAM CADM2 CADM2 CNTN3 CNTN3 LRIG1 LRIG1 SEMA3F SEMA3F CNTFR CNTFR LRIT2 LRIT2 ROR2 ROR2 IGFBP7 IGFBP7 VCAM1 VCAM1 FCRL6 FCRL6 IGSF9 IGSF9 GPA33 GPA33 LRRC24 LRRC24 HMCN2 HMCN2 IGFBPL1 IGFBPL1 LRFN5 LRFN5 TYRO3 TYRO3 ROR1 ROR1 CEACAM18 CEACAM18 LRFN3 LRFN3 PAPLN PAPLN ISLR ISLR LINGO1 LINGO1 ADGRF5 ADGRF5 PTK7 PTK7 LRFN2 LRFN2 MDGA1 MDGA1 AGER AGER AMIGO2 AMIGO2 MYOT MYOT LRRN1 LRRN1 PECAM1 PECAM1 IL12B IL12B LRFN4 LRFN4 PRTG PRTG NFASC NFASC CHL1 CHL1 MYPN MYPN ADAMTSL3 ADAMTSL3 CD276 CD276 PDGFRA PDGFRA LRFN1 LRFN1 IGSF9B IGSF9B MYBPC1 MYBPC1 DCC DCC SIGLEC5 SIGLEC5 OBSL1 OBSL1 CNTN1 CNTN1 NEGR1 NEGR1 A0A287BCF7_PIG A0A287BCF7_PIG HMCN1 HMCN1 CNTN2 CNTN2 MDGA2 MDGA2 MFAP3 MFAP3 IL18R1 IL18R1 VSIG10L VSIG10L PALLD PALLD TTN TTN UNC5D UNC5D AMIGO3 AMIGO3 CD79A CD79A VSIG8 VSIG8 FCRL4 FCRL4 OPCML OPCML L1CAM L1CAM KIRREL2 KIRREL2 FLT1 FLT1 MYBPC2 MYBPC2 LRRC4C LRRC4C CSF1R CSF1R KIRREL1 KIRREL1 A0A5G2QM05_PIG A0A5G2QM05_PIG MCAM MCAM KIT KIT CLMP CLMP ROBO1 ROBO1 LOC110260994 LOC110260994 MAG MAG NRG2 NRG2 LOC100515209 LOC100515209 CNTN4 CNTN4 IL6R IL6R CADM4 CADM4 DSCAML1 DSCAML1 OBSCN OBSCN JAM3 JAM3 F11R F11R NECTIN4 NECTIN4 IGSF3 IGSF3 LRIG2 LRIG2 CNTN5 CNTN5 LRRN2 LRRN2 MYOM1 MYOM1 CADM1 CADM1 MYBPC3 MYBPC3 NCAM2 NCAM2 VSIG10L2 VSIG10L2 MUSK MUSK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LINGO3Leucine rich repeat and Ig domain containing 3. (592 aa)
IGSF11Immunoglobulin superfamily member 11. (432 aa)
CD3GT-cell surface glycoprotein CD3 gamma chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of [...] (176 aa)
FGFR3Fibroblast growth factor receptor. (855 aa)
FGFRL1Fibroblast growth factor receptor like 1. (566 aa)
VSIG4V-set and immunoglobulin domain containing 4. (399 aa)
ALPK3Alpha-type protein kinase domain-containing protein. (229 aa)
ADAMTSL1ADAMTS like 1. (1763 aa)
NPTNNeuroplastin. (412 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
KAZALD1Kazal-type serine protease inhibitor domain-containing protein 1 isoform X1. (315 aa)
SPEGNBSPEG neighbor. (236 aa)
CEACAM21Carcinoembryonic antigen-related cell adhesion molecule 21 isoform X4. (268 aa)
NPHS1NPHS1 adhesion molecule, nephrin. (1239 aa)
SIGLEC1Sialoadhesin; Macrophage-restricted adhesion molecule that mediates sialic- acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid. Binds to SPN/CD43 on T-cells. May play a role in hemopoiesis (By similarity). Acts as an endocytic receptor mediating clathrin dependent endocytosis. In case of porcine reproductive and respiratory syndrome virus (PRRSV), mediates virion attachment and internalization into alveolar macrophages through a clathrin-coated dependent process. B [...] (1730 aa)
LRRC4BLeucine rich repeat containing 4B. (714 aa)
ISLR2Immunoglobulin superfamily containing leucine rich repeat 2. (806 aa)
SPEGUncharacterized protein. (869 aa)
A0A286ZV66_PIGUncharacterized protein. (550 aa)
CNTN6Contactin 6. (1028 aa)
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (548 aa)
CXADRUncharacterized protein. (419 aa)
NEO1Neogenin 1. (1465 aa)
CADM3Cell adhesion molecule 3 isoform 1. (430 aa)
FCRL3Fc receptor-like protein 3 isoform 1. (729 aa)
LRIT1Leucine rich repeat, Ig-like and transmembrane domains 1. (652 aa)
A0A286ZNZ8_PIGUncharacterized protein. (1269 aa)
UNC5CUnc-5 netrin receptor C. (937 aa)
MYOM2Uncharacterized protein. (888 aa)
VSIG10V-set and immunoglobulin domain containing 10. (536 aa)
JAM2Junctional adhesion molecule 2. (307 aa)
UNC5BUnc-5 netrin receptor B. (934 aa)
PTPRFProtein tyrosine phosphatase receptor type F. (1919 aa)
A0A286ZIE2_PIGUncharacterized protein. (441 aa)
LOC100521529Ig-like domain-containing protein. (481 aa)
FGFR2Fibroblast growth factor receptor. (820 aa)
FGFR1Fibroblast growth factor receptor. (820 aa)
MALT1Mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform X1. (850 aa)
CEACAM16Carcinoembryonic antigen related cell adhesion molecule 16. (424 aa)
NCAM1Neural cell adhesion molecule 1. (1140 aa)
SIRPB2Signal regulatory protein beta 2. (330 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1360 aa)
FCER1AFc fragment of IgE receptor Ia. (261 aa)
IGFN1Uncharacterized protein. (1253 aa)
LOC100513863Uncharacterized protein. (709 aa)
GP6Ig-like domain-containing protein. (319 aa)
HEPACAM2HEPACAM family member 2. (524 aa)
MYBPHMyosin-binding protein H. (511 aa)
CDONCell adhesion associated, oncogene regulated. (1247 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1946 aa)
LSAMPLimbic system associated membrane protein. (345 aa)
CEACAM20Carcinoembryonic antigen related cell adhesion molecule 20. (599 aa)
ROBO2Roundabout homolog 2 isoform X5. (1439 aa)
PXDNPeroxidasin. (1529 aa)
FCRLAFc receptor like A. (376 aa)
CEACAM1Uncharacterized protein. (438 aa)
LINGO4Leucine rich repeat and Ig domain containing 4. (593 aa)
FCRL5Uncharacterized protein. (700 aa)
FSTL5Follistatin like 5. (856 aa)
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (580 aa)
TRIOTrio Rho guanine nucleotide exchange factor. (3109 aa)
LRRN3Leucine-rich repeat neuronal protein 3. (708 aa)
LRRC4Leucine rich repeat containing 4. (660 aa)
CCDC141Ig-like domain-containing protein. (1524 aa)
KIRREL3Kirre like nephrin family adhesion molecule 3. (794 aa)
ROBO4Roundabout guidance receptor 4. (1010 aa)
ROBO3Roundabout guidance receptor 3. (1387 aa)
ESAMEndothelial cell adhesion molecule. (394 aa)
VSIG2V-set and immunoglobulin domain containing 2. (331 aa)
NECTIN1Nectin-1; Probably involved in cell adhesion. Receptor for alphaherpesvirus (HSV-1, HSV-2 and pseudorabies virus) entry into cells; Belongs to the nectin family. (515 aa)
CD3ET-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...] (267 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1181 aa)
FSTL4Follistatin like 4. (848 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1362 aa)
CILP2Cartilage intermediate layer protein 2. (1163 aa)
ICAM5Intercellular adhesion molecule 5. (922 aa)
CD22CD22 molecule. (890 aa)
IL1RAPL1Interleukin 1 receptor accessory protein like 1. (696 aa)
DSCAMDS cell adhesion molecule. (2008 aa)
CADM2Cell adhesion molecule 2. (438 aa)
CNTN3Contactin-3. (1028 aa)
LRIG1Leucine rich repeats and immunoglobulin like domains 1. (1112 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (777 aa)
CNTFRCiliary neurotrophic factor receptor. (438 aa)
LRIT2Leucine rich repeat, Ig-like and transmembrane domains 2. (566 aa)
ROR2Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (940 aa)
IGFBP7Uncharacterized protein. (278 aa)
VCAM1Uncharacterized protein. (537 aa)
FCRL6Fc receptor-like protein 6 isoform X2. (480 aa)
IGSF9Immunoglobulin superfamily member 9. (1186 aa)
GPA33Cell surface A33 antigen. (320 aa)
LRRC24Leucine rich repeat containing 24. (509 aa)
HMCN2Hemicentin 2. (5047 aa)
IGFBPL1Insulin-like growth factor-binding protein-like 1. (275 aa)
LRFN5Leucine-rich repeat and fibronectin type-III domain-containing protein 5 isoform X1. (723 aa)
TYRO3TYRO3 protein tyrosine kinase. (913 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa)
CEACAM18Carcinoembryonic antigen-related cell adhesion molecule 18. (370 aa)
LRFN3Leucine rich repeat and fibronectin type III domain containing 3. (627 aa)
PAPLNPapilin, proteoglycan like sulfated glycoprotein. (961 aa)
ISLRImmunoglobulin superfamily containing leucine rich repeat. (436 aa)
LINGO1Leucine rich repeat and Ig domain containing 1. (620 aa)
ADGRF5Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1340 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
LRFN2Leucine-rich repeat and fibronectin type-III domain-containing protein 2. (791 aa)
MDGA1MAM domain-containing glycosylphosphatidylinositol anchor protein 1 preproprotein. (955 aa)
AGERAdvanced glycosylation end-product specific receptor. (487 aa)
AMIGO2Adhesion molecule with Ig like domain 2. (521 aa)
MYOTMyotilin. (636 aa)
LRRN1Leucine-rich repeat neuronal protein 1. (716 aa)
PECAM1Platelet endothelial cell adhesion molecule; Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-692 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions. Heterophilic interaction with CD177 plays a role in transendothelial migration of neutr [...] (740 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. (324 aa)
LRFN4Leucine-rich repeat and fibronectin type-III domain-containing protein 4 isoform X1. (636 aa)
PRTGProtogenin. (1200 aa)
NFASCNeurofascin. (1587 aa)
CHL1Cell adhesion molecule L1 like. (1225 aa)
MYPNMyopalladin isoform a. (1320 aa)
ADAMTSL3ADAMTS like 3. (1642 aa)
CD276CD276 molecule. (537 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1088 aa)
LRFN1Leucine rich repeat and fibronectin type III domain containing 1. (766 aa)
IGSF9BImmunoglobulin superfamily member 9B. (1442 aa)
MYBPC1Myosin binding protein C, slow type. (1233 aa)
DCCDCC netrin 1 receptor. (1423 aa)
SIGLEC5Uncharacterized protein. (556 aa)
OBSL1Obscurin-like protein 1 isoform X2. (1896 aa)
CNTN1Contactin 1. (1018 aa)
NEGR1Neuronal growth regulator 1. (354 aa)
A0A287BCF7_PIGIg-like domain-containing protein. (124 aa)
HMCN1Hemicentin-1. (5636 aa)
CNTN2Contactin 2. (1038 aa)
MDGA2MAM domain containing glycosylphosphatidylinositol anchor 2. (1025 aa)
MFAP3Microfibril-associated glycoprotein 3 isoform 1. (362 aa)
IL18R1Interleukin 18 receptor 1. (539 aa)
VSIG10LV-set and immunoglobulin domain containing 10 like. (863 aa)
PALLDPalladin, cytoskeletal associated protein. (1350 aa)
TTNUncharacterized protein. (563 aa)
UNC5DUnc-5 netrin receptor D. (956 aa)
AMIGO3Adhesion molecule with Ig like domain 3. (508 aa)
CD79AIg-like domain-containing protein. (234 aa)
VSIG8V-set and immunoglobulin domain containing 8. (414 aa)
FCRL4Fc receptor like 4. (578 aa)
OPCMLOpioid-binding protein/cell adhesion molecule isoform a preproprotein. (345 aa)
L1CAML1 cell adhesion molecule. (1256 aa)
KIRREL2Kirre like nephrin family adhesion molecule 2. (711 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1302 aa)
MYBPC2Myosin binding protein C, fast type. (1290 aa)
LRRC4CLeucine rich repeat containing 4C. (640 aa)
CSF1RColony stimulating factor 1 receptor. (1053 aa)
KIRREL1Kirre like nephrin family adhesion molecule 1. (773 aa)
A0A5G2QM05_PIGUncharacterized protein. (545 aa)
MCAMMelanoma cell adhesion molecule. (667 aa)
KITMast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (975 aa)
CLMPCXADR like membrane protein. (399 aa)
ROBO1Roundabout guidance receptor 1. (1687 aa)
LOC110260994Ig-like domain-containing protein. (373 aa)
MAGMyelin associated glycoprotein. (625 aa)
NRG2Neuregulin 2. (858 aa)
LOC100515209Ig-like domain-containing protein. (321 aa)
CNTN4Contactin 4. (1024 aa)
IL6RInterleukin-6 receptor subunit alpha; Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis; Belongs to the type I cytokine receptor family. Type 3 subfamily. (491 aa)
CADM4Cell adhesion molecule 4. (405 aa)
DSCAML1DS cell adhesion molecule like 1. (2111 aa)
OBSCNUncharacterized protein. (7182 aa)
JAM3Junctional adhesion molecule 3. (360 aa)
F11RUncharacterized protein. (347 aa)
NECTIN4Nectin cell adhesion molecule 4. (525 aa)
IGSF3Immunoglobulin superfamily member 3. (1210 aa)
LRIG2Leucine rich repeats and immunoglobulin like domains 2. (1065 aa)
CNTN5Contactin 5. (1101 aa)
LRRN2Leucine-rich repeat neuronal protein 2 isoform X1. (712 aa)
MYOM1Myomesin-1 isoform a. (1656 aa)
CADM1Cell adhesion molecule 1. (473 aa)
MYBPC3Myosin binding protein C, cardiac. (1499 aa)
NCAM2Neural cell adhesion molecule 2. (837 aa)
VSIG10L2V-set and immunoglobulin domain containing 10 like 2. (766 aa)
MUSKMuscle associated receptor tyrosine kinase. (869 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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