STRINGSTRING
PPP2CA PPP2CA PPEF2 PPEF2 PPP1CC PPP1CC PPP4C PPP4C PPP1CB PPP1CB PPP3CB PPP3CB PPEF1 PPEF1 PPP3CA PPP3CA PPP6C PPP6C PPP5C PPP5C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP2CASerine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity). (309 aa)
PPEF2Serine/threonine-protein phosphatase with EF-hands. (751 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (369 aa)
PPP4CSerine/threonine-protein phosphatase. (307 aa)
PPP1CBSerine/threonine-protein phosphatase PP1-beta catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progressi [...] (389 aa)
PPP3CBSerine/threonine-protein phosphatase. (527 aa)
PPEF1Serine/threonine-protein phosphatase with EF-hands. (652 aa)
PPP3CASerine/threonine-protein phosphatase. (523 aa)
PPP6CSerine/threonine-protein phosphatase. (305 aa)
PPP5CSerine/threonine-protein phosphatase. (499 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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