(20 nodes) LSM domain superfamily network (Sus scrofa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LSM7	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (150 aa)
	LSM2	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
	LSM10	LSM10, U7 small nuclear RNA associated. (121 aa)
	A0A287AZB7_PIG	Uncharacterized protein. (65 aa)
	SNRPB	Small nuclear ribonucleoprotein-associated protein. (231 aa)
	LSM11	LSM11, U7 small nuclear RNA associated. (357 aa)
	A0A286ZN63_PIG	Sm domain-containing protein. (68 aa)
	LSM6	LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (124 aa)
	ATXN2	Ataxin 2. (1335 aa)
	SNRPG	Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
	SNRPE	Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa)
	SNRPN	Small nuclear ribonucleoprotein-associated protein. (250 aa)
	NAA38	Sm domain-containing protein. (265 aa)
	SNRPD3	Sm domain-containing protein. (281 aa)
	LSM14B	Protein LSM14 homolog B isoform X5. (502 aa)
	A0A287BAW7_PIG	Sm domain-containing protein. (117 aa)
	LSM8	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (127 aa)
	SNRPD1	Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa)
	SNRPF	Sm domain-containing protein. (86 aa)
	LSM3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (105 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A286ZN63_PIG	A0A287AZB7_PIG	ENSSSCP00000032898	ENSSSCP00000049310	Sm domain-containing protein.	Uncharacterized protein.	0.907
A0A286ZN63_PIG	A0A287BAW7_PIG	ENSSSCP00000032898	ENSSSCP00000053209	Sm domain-containing protein.	Sm domain-containing protein.	0.608
A0A286ZN63_PIG	LSM10	ENSSSCP00000032898	ENSSSCP00000051263	Sm domain-containing protein.	LSM10, U7 small nuclear RNA associated.	0.725
A0A286ZN63_PIG	LSM2	ENSSSCP00000032898	ENSSSCP00000051484	Sm domain-containing protein.	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.952
A0A286ZN63_PIG	LSM3	ENSSSCP00000032898	ENSSSCP00000074370	Sm domain-containing protein.	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.916
A0A286ZN63_PIG	LSM6	ENSSSCP00000032898	ENSSSCP00000032187	Sm domain-containing protein.	LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated.	0.957
A0A286ZN63_PIG	LSM7	ENSSSCP00000032898	ENSSSCP00000073302	Sm domain-containing protein.	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated.	0.945
A0A286ZN63_PIG	LSM8	ENSSSCP00000032898	ENSSSCP00000068189	Sm domain-containing protein.	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.957
A0A286ZN63_PIG	NAA38	ENSSSCP00000032898	ENSSSCP00000019038	Sm domain-containing protein.	Sm domain-containing protein.	0.608
A0A286ZN63_PIG	SNRPD1	ENSSSCP00000032898	ENSSSCP00000004008	Sm domain-containing protein.	Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA.	0.868
A0A286ZN63_PIG	SNRPD3	ENSSSCP00000032898	ENSSSCP00000010731	Sm domain-containing protein.	Sm domain-containing protein.	0.934
A0A286ZN63_PIG	SNRPE	ENSSSCP00000032898	ENSSSCP00000022254	Sm domain-containing protein.	Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development.	0.907
A0A286ZN63_PIG	SNRPF	ENSSSCP00000032898	ENSSSCP00000000958	Sm domain-containing protein.	Sm domain-containing protein.	0.943
A0A286ZN63_PIG	SNRPG	ENSSSCP00000032898	ENSSSCP00000025138	Sm domain-containing protein.	Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.	0.948
A0A286ZN63_PIG	SNRPN	ENSSSCP00000032898	ENSSSCP00000021510	Sm domain-containing protein.	Small nuclear ribonucleoprotein-associated protein.	0.812
A0A287AZB7_PIG	A0A286ZN63_PIG	ENSSSCP00000049310	ENSSSCP00000032898	Uncharacterized protein.	Sm domain-containing protein.	0.907
A0A287AZB7_PIG	A0A287BAW7_PIG	ENSSSCP00000049310	ENSSSCP00000053209	Uncharacterized protein.	Sm domain-containing protein.	0.671
A0A287AZB7_PIG	LSM10	ENSSSCP00000049310	ENSSSCP00000051263	Uncharacterized protein.	LSM10, U7 small nuclear RNA associated.	0.865
A0A287AZB7_PIG	LSM2	ENSSSCP00000049310	ENSSSCP00000051484	Uncharacterized protein.	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.951
A0A287AZB7_PIG	LSM3	ENSSSCP00000049310	ENSSSCP00000074370	Uncharacterized protein.	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.911