STRINGSTRING
CSDC2 CSDC2 NARS1 NARS1 MCM9 MCM9 LIN28A LIN28A HELZ2 HELZ2 RPS11 RPS11 PSMC1 PSMC1 POLR3H POLR3H MCM6 MCM6 KARS1 KARS1 NABP2 NABP2 RNGTT RNGTT EIF1AX EIF1AX SSBP1 SSBP1 PNPT1 PNPT1 MNDA MNDA MCM4 MCM4 TTC14 TTC14 MRPS12 MRPS12 EIF5A EIF5A MCM7 MCM7 EIF5A2 EIF5A2 PSMC4 PSMC4 A0A287B5R7_PIG A0A287B5R7_PIG NARS2 NARS2 A0A287B8J8_PIG A0A287B8J8_PIG LIN28B LIN28B PSMC6 PSMC6 DIS3L2 DIS3L2 CARHSP1 CARHSP1 CSDE1 CSDE1 A0A287BQY7_PIG A0A287BQY7_PIG MCM10 MCM10 DIS3 DIS3 MCM5 MCM5 EIF1AD EIF1AD PSMC5 PSMC5 PSMC3 PSMC3 YBX1 YBX1 RPL8 RPL8 POLR2G POLR2G POLR2H POLR2H LIG1 LIG1 EXOSC2 EXOSC2 AIMP1 AIMP1 RPA2 RPA2 DHX8 DHX8 SUPT6H SUPT6H YBX2 YBX2 MCM3 MCM3 YARS1 YARS1 PSMC2 PSMC2 RMI2 RMI2 LIG3 LIG3 RPA3 RPA3 RPA1 RPA1 LOC100523526 LOC100523526 YBX3 YBX3 DIS3L DIS3L EXOSC3 EXOSC3 SPOUT1 SPOUT1 MCM8 MCM8 MRPS17 MRPS17 F1RWB7_PIG F1RWB7_PIG LIG4 LIG4 CCAR1 CCAR1 PDCD11 PDCD11 RADX RADX RPS28 RPS28 RPS23 RPS23 DDIAS DDIAS BRCA2 BRCA2 A0A286ZLV4_PIG A0A286ZLV4_PIG A0A286ZS50_PIG A0A286ZS50_PIG A0A286ZSP8_PIG A0A286ZSP8_PIG A0A286ZWW9_PIG A0A286ZWW9_PIG DARS2 DARS2 NABP1 NABP1 DARS1 DARS1 EIF2S1 EIF2S1 MRPL2 MRPL2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CSDC2Cold shock domain containing C2. (153 aa)
NARS1Asparagine--tRNA ligase, cytoplasmic. (559 aa)
MCM9DNA helicase MCM9 isoform 2; Belongs to the MCM family. (391 aa)
LIN28AProtein lin-28 homolog A. (205 aa)
HELZ2Helicase with zinc finger 2. (2902 aa)
RPS11Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family. (158 aa)
PSMC126S proteasome regulatory subunit 4 isoform a; Belongs to the AAA ATPase family. (440 aa)
POLR3HDNA-directed RNA polymerase III subunit RPC8 isoform X1. (204 aa)
MCM6DNA helicase; Belongs to the MCM family. (821 aa)
KARS1Lysine--tRNA ligase. (803 aa)
NABP2SOSS complex subunit B1 isoform X1. (211 aa)
RNGTTPolynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (623 aa)
EIF1AXEukaryotic translation initiation factor 1A, X-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (144 aa)
SSBP1Single stranded DNA binding protein 1. (163 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1, mitochondrial. (784 aa)
MNDAMyeloid cell nuclear differentiation antigen. (410 aa)
MCM4DNA helicase; Belongs to the MCM family. (882 aa)
TTC14Tetratricopeptide repeat protein 14 isoform a. (772 aa)
MRPS12Mitochondrial ribosomal protein S12; Belongs to the universal ribosomal protein uS12 family. (152 aa)
EIF5AeIF-5a domain-containing protein. (311 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa)
EIF5A2Eukaryotic translation initiation factor 5A. (153 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
A0A287B5R7_PIGRibosomal_L2_C domain-containing protein. (145 aa)
NARS2Asparaginyl-tRNA synthetase 2, mitochondrial. (477 aa)
A0A287B8J8_PIGUncharacterized protein. (617 aa)
LIN28BLin-28 homolog B. (258 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (481 aa)
DIS3L2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (914 aa)
CARHSP1Calcium regulated heat stable protein 1. (146 aa)
CSDE1Cold shock domain containing E1. (851 aa)
A0A287BQY7_PIGCSD_1 domain-containing protein. (380 aa)
MCM10Minichromosome maintenance 10 replication initiation factor. (943 aa)
DIS3DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (958 aa)
MCM5DNA helicase; Belongs to the MCM family. (733 aa)
EIF1ADEukaryotic translation initiation factor 1A domain containing. (175 aa)
PSMC526S proteasome regulatory subunit 8; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC5 belongs to the heterohexameric ring of AAA (ATPases associated with [...] (435 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (629 aa)
YBX1Y-box binding protein 1. (419 aa)
RPL8Ribosomal_L2_C domain-containing protein. (319 aa)
POLR2GRNA polymerase II subunit G. (231 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (153 aa)
LIG1DNA ligase. (916 aa)
EXOSC2Exosome component 2. (271 aa)
AIMP1Aminoacyl tRNA synthetase complex interacting multifunctional protein 1. (335 aa)
RPA2RPA_C domain-containing protein. (270 aa)
DHX8DEAH-box helicase 8. (1211 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1603 aa)
YBX2Y-box binding protein 2. (480 aa)
MCM3DNA helicase; Belongs to the MCM family. (808 aa)
YARS1Tyrosine--tRNA ligase. (528 aa)
PSMC2AAA domain-containing protein; Belongs to the AAA ATPase family. (433 aa)
RMI2RecQ-mediated genome instability protein 2. (150 aa)
LIG3DNA ligase. (995 aa)
RPA3Replication protein A3. (121 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
LOC100523526Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (143 aa)
YBX3Y-box binding protein 3. (380 aa)
DIS3LDIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (1054 aa)
EXOSC3Exosome complex component RRP40 isoform 1. (275 aa)
SPOUT1Putative methyltransferase C9orf114 homolog isoform X1. (398 aa)
MCM8MCM domain-containing protein; Belongs to the MCM family. (831 aa)
MRPS17Uncharacterized protein. (130 aa)
F1RWB7_PIGCSD_1 domain-containing protein. (264 aa)
LIG4DNA ligase. (910 aa)
CCAR1Cell division cycle and apoptosis regulator 1. (1152 aa)
PDCD11Programmed cell death 11. (1875 aa)
RADXRPA1 related single stranded DNA binding protein, X-linked. (857 aa)
RPS2840S ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family. (69 aa)
RPS2340S ribosomal protein S23; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] (143 aa)
DDIASDNA damage induced apoptosis suppressor. (991 aa)
BRCA2Tower domain-containing protein. (1163 aa)
A0A286ZLV4_PIGUncharacterized protein. (171 aa)
A0A286ZS50_PIGUncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (143 aa)
A0A286ZSP8_PIGGamma-interferon-inducible protein 16 isoform 1. (585 aa)
A0A286ZWW9_PIGUncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (91 aa)
DARS2Aspartyl-tRNA synthetase 2, mitochondrial. (641 aa)
NABP1Uncharacterized protein. (204 aa)
DARS1Aspartyl-tRNA synthetase. (468 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit 1; Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre- initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF- 2 must exchange with GTP by way of a reaction catalyzed [...] (315 aa)
MRPL2Mitochondrial ribosomal protein L2. (306 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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