(27 nodes) RNA helicase, DEAD-box type, Q motif network (Sus scrofa)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DDX6	Putative ATP-dependent RNA helicase DDX6 isoform X1; Belongs to the DEAD box helicase family. (483 aa)
	DDX55	RNA helicase. (600 aa)
	DDX47	Putative ATP-dependent RNA helicase DDX47; Belongs to the DEAD box helicase family. (493 aa)
	DDX39B	Spliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pat [...] (467 aa)
	DDX25	ATP-dependent RNA helicase DDX25 isoform 1. (483 aa)
	DDX39A	DExD-box helicase 39A. (452 aa)
	DDX10	RNA helicase. (877 aa)
	DDX23	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23. (820 aa)
	DDX49	DEAD-box helicase 49; Belongs to the DEAD box helicase family. (476 aa)
	EIF4A1	Eukaryotic translation initiation factor 4A isoform 1; Belongs to the DEAD box helicase family. (406 aa)
	DDX24	DEAD-box helicase 24. (819 aa)
	DDX43	Uncharacterized protein; Belongs to the DEAD box helicase family. (641 aa)
	DDX4	Probable ATP-dependent RNA helicase DDX4; ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycl [...] (744 aa)
	DDX46	DEAD-box helicase 46. (1033 aa)
	DDX19A	DEAD-box helicase 19B. (484 aa)
	DDX20	Putative ATP-dependent RNA helicase DDX20 isoform X1. (832 aa)
	EIF4A2	Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family. (410 aa)
	DDX53	Uncharacterized protein; Belongs to the DEAD box helicase family. (630 aa)
	DDX52	Putative ATP-dependent RNA helicase DDX52 isoform 1. (599 aa)
	DDX3X	ATP-dependent RNA helicase DDX3X isoform 1; Belongs to the DEAD box helicase family. (662 aa)
	DDX5	DEAD-box helicase 5; Belongs to the DEAD box helicase family. (617 aa)
	DDX27	DEAD-box helicase 27; Belongs to the DEAD box helicase family. (763 aa)
	LOC100624590	ATP-dependent RNA helicase DDX3X isoform 2; Belongs to the DEAD box helicase family. (670 aa)
	DDX28	DEAD-box helicase 28. (540 aa)
	DDX42	DEAD-box helicase 42. (963 aa)
	EIF4A3	Eukaryotic initiation factor 4A-III, N-terminally processed; ATP-dependent RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expr [...] (488 aa)
	DDX54	ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (879 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDX10	DDX19A	ENSSSCP00000015935	ENSSSCP00000074492	RNA helicase.	DEAD-box helicase 19B.	0.564
DDX10	DDX24	ENSSSCP00000015935	ENSSSCP00000002673	RNA helicase.	DEAD-box helicase 24.	0.880
DDX10	DDX25	ENSSSCP00000015935	ENSSSCP00000016144	RNA helicase.	ATP-dependent RNA helicase DDX25 isoform 1.	0.408
DDX10	DDX27	ENSSSCP00000015935	ENSSSCP00000023812	RNA helicase.	DEAD-box helicase 27; Belongs to the DEAD box helicase family.	0.871
DDX10	DDX28	ENSSSCP00000015935	ENSSSCP00000021251	RNA helicase.	DEAD-box helicase 28.	0.754
DDX10	DDX47	ENSSSCP00000015935	ENSSSCP00000039723	RNA helicase.	Putative ATP-dependent RNA helicase DDX47; Belongs to the DEAD box helicase family.	0.800
DDX10	DDX49	ENSSSCP00000015935	ENSSSCP00000025030	RNA helicase.	DEAD-box helicase 49; Belongs to the DEAD box helicase family.	0.673
DDX10	DDX5	ENSSSCP00000015935	ENSSSCP00000056924	RNA helicase.	DEAD-box helicase 5; Belongs to the DEAD box helicase family.	0.589
DDX10	DDX52	ENSSSCP00000015935	ENSSSCP00000024158	RNA helicase.	Putative ATP-dependent RNA helicase DDX52 isoform 1.	0.898
DDX10	DDX54	ENSSSCP00000015935	ENSSSCP00000055689	RNA helicase.	ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.	0.907
DDX10	DDX55	ENSSSCP00000015935	ENSSSCP00000045699	RNA helicase.	RNA helicase.	0.679
DDX10	EIF4A3	ENSSSCP00000015935	ENSSSCP00000018178	RNA helicase.	Eukaryotic initiation factor 4A-III, N-terminally processed; ATP-dependent RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expr [...]	0.687
DDX19A	DDX10	ENSSSCP00000074492	ENSSSCP00000015935	DEAD-box helicase 19B.	RNA helicase.	0.564
DDX19A	DDX24	ENSSSCP00000074492	ENSSSCP00000002673	DEAD-box helicase 19B.	DEAD-box helicase 24.	0.626
DDX19A	DDX27	ENSSSCP00000074492	ENSSSCP00000023812	DEAD-box helicase 19B.	DEAD-box helicase 27; Belongs to the DEAD box helicase family.	0.602
DDX19A	DDX28	ENSSSCP00000074492	ENSSSCP00000021251	DEAD-box helicase 19B.	DEAD-box helicase 28.	0.497
DDX19A	DDX4	ENSSSCP00000074492	ENSSSCP00000063433	DEAD-box helicase 19B.	Probable ATP-dependent RNA helicase DDX4; ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycl [...]	0.410
DDX19A	DDX47	ENSSSCP00000074492	ENSSSCP00000039723	DEAD-box helicase 19B.	Putative ATP-dependent RNA helicase DDX47; Belongs to the DEAD box helicase family.	0.452
DDX19A	DDX49	ENSSSCP00000074492	ENSSSCP00000025030	DEAD-box helicase 19B.	DEAD-box helicase 49; Belongs to the DEAD box helicase family.	0.496
DDX19A	DDX52	ENSSSCP00000074492	ENSSSCP00000024158	DEAD-box helicase 19B.	Putative ATP-dependent RNA helicase DDX52 isoform 1.	0.542