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IFNGR2 | Interferon gamma receptor 2 isoform 1. (369 aa) | ||||
IL22RA2 | Interleukin 22 receptor subunit alpha 2. (231 aa) | ||||
F3 | Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (292 aa) | ||||
IFNAR2 | Uncharacterized protein. (574 aa) | ||||
IL10RB | Interleukin-10 receptor subunit beta. (362 aa) | ||||
IFNAR1 | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). (617 aa) |