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| | TLE2 | TLE family member 2, transcriptional corepressor. (750 aa) |
| | SEC31A | SEC31 homolog A, COPII coat complex component. (1251 aa) |
| | WIPI1 | Uncharacterized protein. (477 aa) |
| | STRN | Striatin isoform X1. (809 aa) |
| | WDR92 | WD repeat-containing protein 92 isoform 1. (357 aa) |
| | WDR54 | WD repeat domain 54. (352 aa) |
| | CIAO1 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. (339 aa) |
| | MLST8 | MTOR associated protein, LST8 homolog. (455 aa) |
| | WDR48 | WD repeat domain 48. (740 aa) |
| | PHIP | Pleckstrin homology domain interacting protein. (1825 aa) |
| | WDR44 | WD repeat-containing protein 44 isoform 1. (913 aa) |
| | PLXND1 | Plexin D1. (1926 aa) |
| | PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (513 aa) |
| | SORCS1 | Sortilin related VPS10 domain containing receptor 1. (1167 aa) |
| | EML3 | EMAP like 3. (1037 aa) |
| | LLGL1 | LLGL scribble cell polarity complex component 1. (1095 aa) |
| | WDR41 | WD repeat-containing protein 41 isoform X1. (459 aa) |
| | PLAA | Phospholipase A2 activating protein. (1044 aa) |
| | ERCC8 | ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (396 aa) |
| | SEC31B | SEC31 homolog B, COPII coat complex component. (1210 aa) |
| | CDC20B | Cell division cycle 20B. (516 aa) |
| | ELP1 | Elongator complex protein 1 isoform 1. (1422 aa) |
| | SEMA3D | Semaphorin-3D isoform X1; Belongs to the semaphorin family. (777 aa) |
| | SEC13 | SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (341 aa) |
| | EML5 | EMAP like 5. (1969 aa) |
| | POC1B | POC1 centriolar protein B. (478 aa) |
| | WDR61 | WD repeat-containing protein 61 isoform a. (305 aa) |
| | WDR93 | WD repeat domain 93. (703 aa) |
| | DCAF11 | DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat LEC14B family. (597 aa) |
| | TEP1 | Telomerase associated protein 1. (2623 aa) |
| | TECPR2 | Uncharacterized protein. (111 aa) |
| | WDR20 | WD repeat domain 20. (612 aa) |
| | TAF1C | TATA-box binding protein associated factor, RNA polymerase I subunit C. (908 aa) |
| | RFWD3 | E3 ubiquitin-protein ligase RFWD3 isoform X1. (781 aa) |
| | EDC4 | Enhancer of mRNA decapping 4. (1402 aa) |
| | WDR88 | WD_REPEATS_REGION domain-containing protein. (241 aa) |
| | WDR62 | WD repeat-containing protein 62; Required for cerebral cortical development. Plays a role in neuronal proliferation and migration (By similarity). Plays a role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and CEP63 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (By similarity). (1541 aa) |
| | GRWD1 | Glutamate rich WD repeat containing 1. (445 aa) |
| | LRRK2 | Uncharacterized protein. (2501 aa) |
| | IFT140 | Intraflagellar transport 140. (1477 aa) |
| | RRP9 | Ribosomal RNA processing 9, U3 small nucleolar RNA binding protein. (475 aa) |
| | EML6 | Echinoderm microtubule-associated protein-like 6. (1958 aa) |
| | PLXNA3 | Plexin A3. (1871 aa) |
| | SEMA4D | Semaphorin-4D isoform X1; Belongs to the semaphorin family. (865 aa) |
| | RAE1 | mRNA export factor; Plays a role in mitotic bipolar spindle formation. Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. (368 aa) |
| | PAK1IP1 | PAK1 interacting protein 1. (370 aa) |
| | TBL1X | Uncharacterized protein. (615 aa) |
| | PLXNA4 | Plexin-A4 isoform X1. (1893 aa) |
| | GNB5 | G protein subunit beta 5. (420 aa) |
| | ERN2 | Endoplasmic reticulum to nucleus signaling 2. (989 aa) |
| | BRWD3 | Bromodomain and WD repeat domain containing 3. (1799 aa) |
| | BCAS3 | BCAS3 microtubule associated cell migration factor. (950 aa) |
| | EML2 | Echinoderm microtubule-associated protein-like 2 isoform 5. (849 aa) |
| | UTP4 | U3 small nucleolar RNA-associated protein 4 homolog isoform 1. (686 aa) |
| | CFAP43 | Cilia and flagella associated protein 43. (1669 aa) |
| | KATNB1 | Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...] (690 aa) |
| | WDR86 | WD_REPEATS_REGION domain-containing protein. (557 aa) |
| | EMC1 | ER membrane protein complex subunit 1. (1075 aa) |
| | SEMA5A | Semaphorin 5A. (1072 aa) |
| | A0A287BS73_PIG | Neurobeachin-like protein 2 isoform X1. (243 aa) |
| | SEMA4F | Ssemaphorin 4F; Belongs to the semaphorin family. (771 aa) |
| | WDR31 | WD repeat domain 31. (376 aa) |
| | NEDD1 | NEDD1 gamma-tubulin ring complex targeting factor. (654 aa) |
| | SORL1 | Sortilin related receptor 1. (2213 aa) |
| | NBEAL2 | Neurobeachin like 2. (2796 aa) |
| | WDSUB1 | WD repeat, sterile alpha motif and U-box domain containing 1. (476 aa) |
| | AHI1 | Abelson helper integration site 1. (1114 aa) |
| | NUP43 | Nucleoporin Nup43 isoform X2. (380 aa) |
| | WDR46 | WD repeat-containing protein 46 isoform 1. (656 aa) |
| | KIF21B | Kinesin family member 21B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1379 aa) |
| | NUP37 | Nucleoporin Nup37. (333 aa) |
| | DCAF7 | DDB1 and CUL4 associated factor 7. (340 aa) |
| | NBEA | Neurobeachin. (2961 aa) |
| | TBC1D31 | TBC1 domain family member 31. (1066 aa) |
| | PIK3R4 | Phosphoinositide-3-kinase regulatory subunit 4. (1302 aa) |
| | LRBA | LPS responsive beige-like anchor protein. (2834 aa) |
| | CORO2A | Coronin; Belongs to the WD repeat coronin family. (505 aa) |
| | WRAP73 | WD repeat containing, antisense to TP73. (460 aa) |
| | DCAF5 | DDB1 and CUL4 associated factor 5. (947 aa) |
| | ZNF106 | Zinc finger protein 106. (1903 aa) |
| | WIPI2 | WD repeat domain, phosphoinositide interacting 2. (559 aa) |
| | CSTF1 | Cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa. (431 aa) |
| | DPH7 | Diphthamide biosynthesis 7. (471 aa) |
| | SEMA4G | Semaphorin 4G; Belongs to the semaphorin family. (838 aa) |
| | WDR7 | WD repeat domain 7. (1487 aa) |
| | STXBP5 | Syntaxin binding protein 5. (1179 aa) |
| | TBL3 | Transducin beta like 3. (889 aa) |
| | CORO1B | Coronin; Belongs to the WD repeat coronin family. (496 aa) |
| | THOC6 | THO complex subunit 6 homolog isoform 1. (406 aa) |
| | SEMA6A | Semaphorin-6A isoform 1; Belongs to the semaphorin family. (1047 aa) |
| | EIF3B | Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (784 aa) |
| | FZR1 | Fizzy and cell division cycle 20 related 1. (493 aa) |
| | WDTC1 | WD and tetratricopeptide repeats 1. (733 aa) |
| | LLGL2 | LLGL scribble cell polarity complex component 2. (1048 aa) |
| | EML1 | EMAP like 1. (923 aa) |
| | CDRT1 | WD_REPEATS_REGION domain-containing protein. (1077 aa) |
| | DYNC1I1 | Cytoplasmic dynein 1 intermediate chain 1 isoform X1. (645 aa) |
| | STRN3 | Striatin 3. (797 aa) |
| | FBXW8 | F-box and WD repeat domain containing 8. (596 aa) |
| | SORCS2 | Sortilin related VPS10 domain containing receptor 2. (1168 aa) |
| | TULP4 | Uncharacterized protein. (679 aa) |
| | RIC1 | RAB6A-GEF complex partner protein 1 isoform X1. (1421 aa) |
| | GNB1 | G protein subunit beta 1. (395 aa) |
| | NWD2 | NACHT and WD repeat domain containing 2. (1742 aa) |
| | DCAF1 | DDB1 and CUL4 associated factor 1. (1511 aa) |
| | WDR81 | WD repeat-containing protein 81 isoform X1. (1945 aa) |
| | FBXW11 | F-box and WD repeat domain containing 11. (542 aa) |
| | SPAG16 | Sperm associated antigen 16. (628 aa) |
| | VPS8 | Vacuolar protein sorting-associated protein 8 homolog isoform a. (1428 aa) |
| | SF3B3 | Splicing factor 3B subunit 3. (1217 aa) |
| | WDR74 | Uncharacterized protein. (388 aa) |
| | PEX7 | Peroxisomal biogenesis factor 7. (308 aa) |
| | TLE1 | TLE family member 1, transcriptional corepressor. (770 aa) |
| | SEMA4A | Semaphorin-4A isoform X2; Belongs to the semaphorin family. (791 aa) |
| | RBBP4 | WD_REPEATS_REGION domain-containing protein. (427 aa) |
| | SEMA4B | Semaphorin 4B; Belongs to the semaphorin family. (835 aa) |
| | TBL1XR1 | Transducin beta like 1 X-linked receptor 1. (526 aa) |
| | WDR97 | WD_REPEATS_REGION domain-containing protein. (795 aa) |
| | SEMA6B | Semaphorin-6B; Belongs to the semaphorin family. (901 aa) |
| | SHKBP1 | SH3KBP1 binding protein 1. (729 aa) |
| | EML4 | EMAP like 4. (992 aa) |
| | FAM234A | Family with sequence similarity 234 member A. (551 aa) |
| | DENND3 | DENN domain containing 3. (1277 aa) |
| | NUP133 | Nucleoporin 133. (1160 aa) |
| | NSMAF | Neutral sphingomyelinase activation associated factor. (923 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1249 aa) |
| | DMWD | DM1 locus, WD repeat containing. (665 aa) |
| | STXBP5L | Syntaxin binding protein 5 like. (1234 aa) |
| | DCAF8 | DDB1 and CUL4 associated factor 8. (639 aa) |
| | NLE1 | Notchless homolog 1. (487 aa) |
| | WDR25 | WD repeat domain 25. (536 aa) |
| | DDB2 | DNA damage-binding protein 2 isoform WT. (448 aa) |
| | PAN2 | PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1198 aa) |
| | WDR59 | WD repeat domain 59. (938 aa) |
| | SEMA3B | Semaphorin 3B; Belongs to the semaphorin family. (747 aa) |
| | PLXNA1 | Plexin A1. (1909 aa) |
| | ATG16L1 | Autophagy-related protein 16-1 isoform X1. (623 aa) |
| | STRN4 | Striatin-4 isoform 2. (891 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1351 aa) |
| | PLXNA2 | Plexin A2. (1937 aa) |
| | CORO1A | Coronin; Belongs to the WD repeat coronin family. (492 aa) |
| | DCAF6 | DDB1-and CUL4-associated factor 6 isoform c. (942 aa) |
| | MAPK8IP3 | Mitogen-activated protein kinase 8 interacting protein 3. (1358 aa) |
| | PALB2 | Partner and localizer of BRCA2. (1189 aa) |
| | CORO6 | Coronin; Belongs to the WD repeat coronin family. (470 aa) |
| | WDR78 | WD repeat-containing protein 78 isoform 1. (812 aa) |
| | SEMA3C | Semaphorin-3C isoform 2; Belongs to the semaphorin family. (751 aa) |
| | WDR4 | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. (416 aa) |
| | WDFY1 | Uncharacterized protein. (415 aa) |
| | DCAF4 | WD_REPEATS_REGION domain-containing protein. (526 aa) |
| | SEMA7A | Semaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (615 aa) |
| | PWP1 | PWP1 homolog, endonuclein. (499 aa) |
| | GNB3 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform 1. (340 aa) |
| | DCAF12 | DDB1 and CUL4 associated factor 12. (458 aa) |
| | IFT80 | Intraflagellar transport 80. (767 aa) |
| | WDR33 | Pre-mRNA 3' end processing protein WDR33 isoform X1. (1336 aa) |
| | I3L6Y1_PIG | WD_REPEATS_REGION domain-containing protein. (391 aa) |
| | ELP2 | Elongator acetyltransferase complex subunit 2. (826 aa) |
| | FSTL5 | Follistatin like 5. (856 aa) |
| | CFAP52 | Cilia-and flagella-associated protein 52 isoform X1. (620 aa) |
| | WRAP53 | WD repeat containing antisense to TP53. (539 aa) |
| | UTP18 | U3 small nucleolar RNA-associated protein 18 homolog. (572 aa) |
| | PPWD1 | Peptidylprolyl isomerase domain and WD repeat-containing protein 1 isoform 1. (646 aa) |
| | FBXW4 | F-box and WD repeat domain containing 4. (630 aa) |
| | TAF5 | Transcription initiation factor TFIID subunit 5 isoform 1. (800 aa) |
| | BUB3 | BUB3 mitotic checkpoint protein. (328 aa) |
| | GNB4 | G protein subunit beta 4. (340 aa) |
| | WDR37 | WD repeat domain 37. (681 aa) |
| | AASDH | Aminoadipate-semialdehyde dehydrogenase. (1076 aa) |
| | TBL2 | Transducin beta like 2. (465 aa) |
| | WDR76 | WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (678 aa) |
| | GEMIN5 | Gem nuclear organelle associated protein 5. (1511 aa) |
| | CDC40 | Pre-mRNA-processing factor 17. (579 aa) |
| | WDR53 | WD repeat-containing protein 53 isoform a. (358 aa) |
| | ARPC1B | Actin related protein 2/3 complex subunit 1B. (440 aa) |
| | DNAI1 | Dynein axonemal intermediate chain 1. (704 aa) |
| | COPB2 | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (907 aa) |
| | NOL10 | Nucleolar protein 10 isoform 1. (688 aa) |
| | TLE4 | TLE family member 4, transcriptional corepressor. (774 aa) |
| | WDR36 | WD repeat domain 36. (895 aa) |
| | NUP214 | Nucleoporin 214. (2016 aa) |
| | FBXW2 | F-box domain-containing protein. (234 aa) |
| | BRWD1 | Bromodomain and WD repeat domain containing 1. (2325 aa) |
| | GTF3C2 | General transcription factor IIIC subunit 2. (892 aa) |
| | PAFAH1B1 | Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa) |
| | WDR1 | WD repeat-containing protein 1 isoform 1. (606 aa) |
| | SEMA6C | Semaphorin-6C isoform X1; Belongs to the semaphorin family. (966 aa) |
| | DYNC1I2 | WD_REPEATS_REGION domain-containing protein. (581 aa) |
| | DMXL1 | Dmx like 1. (3084 aa) |
| | LOC100624648 | F-box-like/WD repeat-containing protein TBL1X isoform a. (529 aa) |
| | WSB1 | WD repeat and SOCS box-containing protein 1 isoform 1. (421 aa) |
| | WDR90 | WD repeat domain 90. (1832 aa) |
| | PRPF4 | U4/U6 small nuclear ribonucleoprotein Prp4 isoform X1. (521 aa) |
| | FBXW7 | F-box and WD repeat domain containing 7. (779 aa) |
| | ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (809 aa) |
| | MST1R | Macrophage stimulating 1 receptor. (1398 aa) |
| | WDR43 | WD repeat-containing protein 43. (681 aa) |
| | CFAP44 | Cilia and flagella associated protein 44. (1846 aa) |
| | EIPR1 | EARP complex and GARP complex interacting protein 1. (387 aa) |
| | RACK1 | Receptor of activated protein C kinase 1, N-terminally processed; Scaffolding protein involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes. Component of the 40S ribosomal subunit involved in translational repression (By similarity). Involved in the initiation of the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation, by promoting ubiquitination of a subset of 40S ribosomal subunits (By similarity). Binds to [...] (317 aa) |
| | WDR72 | WD repeat domain 72. (1113 aa) |
| | DNAI2 | Dynein intermediate chain 2, axonemal isoform X2. (607 aa) |
| | WDR19 | WD repeat domain 19. (1342 aa) |
| | IFT172 | Intraflagellar transport 172. (1738 aa) |
| | SCAP | Sterol regulatory element-binding protein cleavage-activating protein; Escort protein required for cholesterol as well as lipid homeostasis. Regulates export of the SCAP/SREBF complex from the ER upon low cholesterol. Formation of a ternary complex with INSIG at high sterol concentrations leads to masking of an ER-export signal in SCAP and retention of the complex in the ER. Low sterol concentrations trigger release of INSIG, a conformational change in the SSC domain of SCAP, unmasking of the ER export signal, recruitment into COPII-coated vesicles, transport to the Golgi complex, prot [...] (1280 aa) |
| | WDR13 | WD repeat domain 13. (587 aa) |
| | WSB2 | WD repeat and SOCS box containing 2. (448 aa) |
| | WDR66 | WD repeat domain 66. (1209 aa) |
| | PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (457 aa) |
| | WDFY3 | WD repeat and FYVE domain containing 3. (3526 aa) |
| | BBS7 | Bardet-Biedl syndrome 7. (871 aa) |
| | PPP2R2C | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa) |
| | NBAS | Neuroblastoma amplified sequence. (2318 aa) |
| | PREB | Prolactin regulatory element binding. (418 aa) |
| | WDR24 | GATOR complex protein WDR24. (790 aa) |
| | LRWD1 | Leucine rich repeats and WD repeat domain containing 1. (739 aa) |
| | GNB2 | G protein subunit beta 2. (340 aa) |
| | ARPC1A | Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa) |
| | WDR77 | WD repeat domain 77. (342 aa) |
| | WDR3 | WD repeat domain 3. (943 aa) |
| | DCAF13 | DDB1 and CUL4 associated factor 13. (444 aa) |
| | FBXW5 | F-box and WD repeat domain containing 5. (567 aa) |
| | WDR34 | WD repeat domain 34. (419 aa) |
| | WDR38 | WD repeat domain 38. (310 aa) |
| | DCAF10 | DDB1-and CUL4-associated factor 10 isoform X1. (562 aa) |
| | WDHD1 | WD repeat and HMG-box DNA binding protein 1. (1129 aa) |
| | TLE3 | TLE family member 3, transcriptional corepressor. (808 aa) |
| | CORO2B | Coronin; Belongs to the WD repeat coronin family. (554 aa) |
| | MAPKBP1 | Mitogen-activated protein kinase binding protein 1. (1502 aa) |
| | SEMA6D | Semaphorin 6D; Belongs to the semaphorin family. (1086 aa) |
| | DMXL2 | Dmx like 2. (3057 aa) |
| | CDC20 | Cell division cycle protein 20 homolog; Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentia [...] (499 aa) |
| | EIF3I | Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (277 aa) |
| | SNRNP40 | Small nuclear ribonucleoprotein U5 subunit 40. (355 aa) |
| | KCTD3 | Potassium channel tetramerization domain containing 3. (774 aa) |
| | WDR26 | WD repeat domain 26. (664 aa) |
| | SMU1 | Uncharacterized protein. (511 aa) |
| | PLXNB1 | Plexin B1. (2133 aa) |
| | SEMA3F | Semaphorin 3F; Belongs to the semaphorin family. (777 aa) |
| | WDR82 | WD repeat domain 82. (313 aa) |
| | SEMA3G | Semaphorin-3G; Belongs to the semaphorin family. (771 aa) |
| | IFT122 | Intraflagellar transport 122. (1215 aa) |
| | WDR49 | WD repeat domain 49. (1051 aa) |
| | CHAF1B | Chromatin assembly factor 1 subunit B. (555 aa) |
| | F1SPW0_PIG | WD_REPEATS_REGION domain-containing protein. (604 aa) |
| | WDR45 | WD repeat domain 45. (360 aa) |
| | DCAF12L2 | DDB1 and CUL4 associated factor 12 like 2. (464 aa) |
| | PLXNB3 | Plexin B3. (1894 aa) |
| | DDB1 | Damage specific DNA binding protein 1. (1139 aa) |
| | PRPF19 | Pre-mRNA-processing factor 19. (504 aa) |
| | AMBRA1 | Activating molecule in BECN1-regulated autophagy protein 1 isoform X1. (1296 aa) |
| | MED16 | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (837 aa) |
| | WDR18 | WD repeat-containing protein 18. (432 aa) |
| | WDR83 | WD repeat domain-containing protein 83. (311 aa) |
| | FBXW9 | F-box and WD repeat domain containing 9. (458 aa) |
| | UTP15 | Uncharacterized protein. (518 aa) |
| | FSTL4 | Follistatin like 4. (848 aa) |
| | WDR55 | WD repeat-containing protein 55; Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis. Belongs to the WD repeat WDR55 family. (384 aa) |
| | ATG16L2 | Autophagy related 16 like 2. (647 aa) |
| | WDR70 | WD repeat domain 70. (661 aa) |
| | MET | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1381 aa) |
| | WDR91 | WD repeat-containing protein 91. (746 aa) |
| | AAMP | Angio associated migratory cell protein. (388 aa) |
| | WDR12 | Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (423 aa) |
| | WDR75 | WD repeat-containing protein 75 isoform 1. (831 aa) |
| | WDR17 | WD repeat domain 17. (1322 aa) |
| | DTL | Denticleless E3 ubiquitin protein ligase homolog. (729 aa) |
| | COP1 | E3 ubiquitin-protein ligase RFWD2 isoform a. (730 aa) |
| | SEMA3E | Semaphorin-3E isoform 1; Belongs to the semaphorin family. (775 aa) |
| | RBBP5 | RB binding protein 5, histone lysine methyltransferase complex subunit. (517 aa) |
| | VPS11 | Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (941 aa) |
| | EED | Embryonic ectoderm development. (466 aa) |
| | PAAF1 | Proteasomal ATPase-associated factor 1 isoform 2. (415 aa) |
| | ARHGEF17 | DH domain-containing protein. (1043 aa) |
| | CORO1C | Coronin; Belongs to the WD repeat coronin family. (511 aa) |
| | RBBP7 | RB binding protein 7, chromatin remodeling factor. (469 aa) |
| | EIF2A | Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (591 aa) |
| | KIF21A | Kinesin family member 21A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1673 aa) |
| | WDFY4 | WDFY family member 4. (1979 aa) |
| | TLE7 | TLE family member 7. (433 aa) |
| | VPS41 | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (953 aa) |
| | COPA | Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1241 aa) |
| | BTRC | Beta-transducin repeat containing E3 ubiquitin protein ligase. (603 aa) |
| | AAAS | Aladin WD repeat nucleoporin. (554 aa) |
| | WDR47 | WD repeat domain 47. (928 aa) |
| | STRAP | Serine-threonine kinase receptor-associated protein. (350 aa) |
| | A0A5G2QKX6_PIG | CPSF_A domain-containing protein. (200 aa) |
| | WDR11 | WD repeat domain 11. (1223 aa) |
