STRINGSTRING
ITGB7 ITGB7 SEMA7A SEMA7A SEMA3B SEMA3B PLXNA1 PLXNA1 PLXNA4 PLXNA4 ITGB1 ITGB1 SEMA4D SEMA4D ATRN ATRN PLXNA3 PLXNA3 MST1R MST1R PLXNA2 PLXNA2 SEMA3C SEMA3C SEMA6D SEMA6D ATRNL1 ATRNL1 PLXNB1 PLXNB1 SEMA3F SEMA3F SEMA3G SEMA3G PLXNB3 PLXNB3 SEMA3E SEMA3E MET MET SEMA3D SEMA3D ITGB3 ITGB3 PLXND1 PLXND1 SEMA5A SEMA5A SEMA4F SEMA4F PLXDC2 PLXDC2 SEMA4G SEMA4G ITGB5 ITGB5 ITGB8 ITGB8 SEMA4A SEMA4A SEMA4B SEMA4B ITGB2 ITGB2 ITGB6 ITGB6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITGB7Integrin beta; Belongs to the integrin beta chain family. (882 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (615 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (747 aa)
PLXNA1Plexin A1. (1909 aa)
PLXNA4Plexin-A4 isoform X1. (1893 aa)
ITGB1Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] (853 aa)
SEMA4DSemaphorin-4D isoform X1; Belongs to the semaphorin family. (865 aa)
ATRNAttractin. (1416 aa)
PLXNA3Plexin A3. (1871 aa)
MST1RMacrophage stimulating 1 receptor. (1398 aa)
PLXNA2Plexin A2. (1937 aa)
SEMA3CSemaphorin-3C isoform 2; Belongs to the semaphorin family. (751 aa)
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1086 aa)
ATRNL1Attractin like 1. (1382 aa)
PLXNB1Plexin B1. (2133 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (777 aa)
SEMA3GSemaphorin-3G; Belongs to the semaphorin family. (771 aa)
PLXNB3Plexin B3. (1894 aa)
SEMA3ESemaphorin-3E isoform 1; Belongs to the semaphorin family. (775 aa)
METHepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1381 aa)
SEMA3DSemaphorin-3D isoform X1; Belongs to the semaphorin family. (777 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (835 aa)
PLXND1Plexin D1. (1926 aa)
SEMA5ASemaphorin 5A. (1072 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (771 aa)
PLXDC2Plexin domain containing 2. (558 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (838 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (800 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (722 aa)
SEMA4ASemaphorin-4A isoform X2; Belongs to the semaphorin family. (791 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (835 aa)
ITGB2Integrin beta-2; Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor [...] (903 aa)
ITGB6Integrin beta-6; Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity). It recognizes the sequence R-G-D in its ligands (By similarity). ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R- G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (By similarity). (854 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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