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PWP1 PWP1 GNB3 GNB3 POC1B POC1B WDR61 WDR61 WDR88 WDR88 GRWD1 GRWD1 SNRNP40 SNRNP40 CORO2B CORO2B TLE3 TLE3 WDHD1 WDHD1 WDR38 WDR38 DCAF13 DCAF13 WDR3 WDR3 WDR77 WDR77 GNB2 GNB2 LRWD1 LRWD1 WDR24 WDR24 MLST8 MLST8 CIAO1 CIAO1 STRN STRN WDFY3 WDFY3 WSB2 WSB2 TAF5 TAF5 SMU1 SMU1 WDR49 WDR49 CHAF1B CHAF1B PRPF19 PRPF19 AMBRA1 AMBRA1 WDR18 WDR18 WDR83 WDR83 FBXW9 FBXW9 UTP15 UTP15 WDR55 WDR55 ATG16L2 ATG16L2 EED EED COP1 COP1 DTL DTL WDR17 WDR17 WDR12 WDR12 AAMP AAMP UTP18 UTP18 CFAP52 CFAP52 DCAF12 DCAF12 CORO1C CORO1C CORO6 CORO6 WDFY1 WDFY1 PRPF4 PRPF4 FBXW7 FBXW7 CFAP44 CFAP44 EIPR1 EIPR1 RACK1 RACK1 WDR72 WDR72 SCAP SCAP RRP9 RRP9 RAE1 RAE1 TBL1X TBL1X GNB5 GNB5 PEX7 PEX7 BRWD3 BRWD3 TLE4 TLE4 FBXW2 FBXW2 BRWD1 BRWD1 GTF3C2 GTF3C2 PAFAH1B1 PAFAH1B1 WDR1 WDR1 LOC100624648 LOC100624648 WSB1 WSB1 CORO1A CORO1A WDR53 WDR53 CDC40 CDC40 GEMIN5 GEMIN5 TBL2 TBL2 WDR37 WDR37 GNB4 GNB4 STRN4 STRN4 ATG16L1 ATG16L1 WDR59 WDR59 DDB2 DDB2 NLE1 NLE1 STXBP5L STXBP5L APAF1 APAF1 DENND3 DENND3 WDR97 WDR97 TBL1XR1 TBL1XR1 RBBP4 RBBP4 TLE1 TLE1 RBBP7 RBBP7 KIF21A KIF21A WDFY4 WDFY4 EML5 EML5 CDC20B CDC20B SEC31B SEC31B ERCC8 ERCC8 WDR41 WDR41 PHIP PHIP WDR48 WDR48 TLE2 TLE2 WDR11 WDR11 WDR47 WDR47 AAAS AAAS BTRC BTRC COPA COPA KATNB1 KATNB1 WDR86 WDR86 WDR31 WDR31 NEDD1 NEDD1 WDSUB1 WDSUB1 NUP43 NUP43 KIF21B KIF21B NUP37 NUP37 DCAF7 DCAF7 CORO2A CORO2A CSTF1 CSTF1 DPH7 DPH7 WDR7 WDR7 TBL3 TBL3 CORO1B CORO1B THOC6 THOC6 FZR1 FZR1 STRN3 STRN3 GNB1 GNB1 FBXW11 FBXW11 SPAG16 SPAG16
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PWP1PWP1 homolog, endonuclein. (499 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform 1. (340 aa)
POC1BPOC1 centriolar protein B. (478 aa)
WDR61WD repeat-containing protein 61 isoform a. (305 aa)
WDR88WD_REPEATS_REGION domain-containing protein. (241 aa)
GRWD1Glutamate rich WD repeat containing 1. (445 aa)
SNRNP40Small nuclear ribonucleoprotein U5 subunit 40. (355 aa)
CORO2BCoronin; Belongs to the WD repeat coronin family. (554 aa)
TLE3TLE family member 3, transcriptional corepressor. (808 aa)
WDHD1WD repeat and HMG-box DNA binding protein 1. (1129 aa)
WDR38WD repeat domain 38. (310 aa)
DCAF13DDB1 and CUL4 associated factor 13. (444 aa)
WDR3WD repeat domain 3. (943 aa)
WDR77WD repeat domain 77. (342 aa)
GNB2G protein subunit beta 2. (340 aa)
LRWD1Leucine rich repeats and WD repeat domain containing 1. (739 aa)
WDR24GATOR complex protein WDR24. (790 aa)
MLST8MTOR associated protein, LST8 homolog. (455 aa)
CIAO1Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. (339 aa)
STRNStriatin isoform X1. (809 aa)
WDFY3WD repeat and FYVE domain containing 3. (3526 aa)
WSB2WD repeat and SOCS box containing 2. (448 aa)
TAF5Transcription initiation factor TFIID subunit 5 isoform 1. (800 aa)
SMU1Uncharacterized protein. (511 aa)
WDR49WD repeat domain 49. (1051 aa)
CHAF1BChromatin assembly factor 1 subunit B. (555 aa)
PRPF19Pre-mRNA-processing factor 19. (504 aa)
AMBRA1Activating molecule in BECN1-regulated autophagy protein 1 isoform X1. (1296 aa)
WDR18WD repeat-containing protein 18. (432 aa)
WDR83WD repeat domain-containing protein 83. (311 aa)
FBXW9F-box and WD repeat domain containing 9. (458 aa)
UTP15Uncharacterized protein. (518 aa)
WDR55WD repeat-containing protein 55; Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis. Belongs to the WD repeat WDR55 family. (384 aa)
ATG16L2Autophagy related 16 like 2. (647 aa)
EEDEmbryonic ectoderm development. (466 aa)
COP1E3 ubiquitin-protein ligase RFWD2 isoform a. (730 aa)
DTLDenticleless E3 ubiquitin protein ligase homolog. (729 aa)
WDR17WD repeat domain 17. (1322 aa)
WDR12Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (423 aa)
AAMPAngio associated migratory cell protein. (388 aa)
UTP18U3 small nucleolar RNA-associated protein 18 homolog. (572 aa)
CFAP52Cilia-and flagella-associated protein 52 isoform X1. (620 aa)
DCAF12DDB1 and CUL4 associated factor 12. (458 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (511 aa)
CORO6Coronin; Belongs to the WD repeat coronin family. (470 aa)
WDFY1Uncharacterized protein. (415 aa)
PRPF4U4/U6 small nuclear ribonucleoprotein Prp4 isoform X1. (521 aa)
FBXW7F-box and WD repeat domain containing 7. (779 aa)
CFAP44Cilia and flagella associated protein 44. (1846 aa)
EIPR1EARP complex and GARP complex interacting protein 1. (387 aa)
RACK1Receptor of activated protein C kinase 1, N-terminally processed; Scaffolding protein involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes. Component of the 40S ribosomal subunit involved in translational repression (By similarity). Involved in the initiation of the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation, by promoting ubiquitination of a subset of 40S ribosomal subunits (By similarity). Binds to [...] (317 aa)
WDR72WD repeat domain 72. (1113 aa)
SCAPSterol regulatory element-binding protein cleavage-activating protein; Escort protein required for cholesterol as well as lipid homeostasis. Regulates export of the SCAP/SREBF complex from the ER upon low cholesterol. Formation of a ternary complex with INSIG at high sterol concentrations leads to masking of an ER-export signal in SCAP and retention of the complex in the ER. Low sterol concentrations trigger release of INSIG, a conformational change in the SSC domain of SCAP, unmasking of the ER export signal, recruitment into COPII-coated vesicles, transport to the Golgi complex, prot [...] (1280 aa)
RRP9Ribosomal RNA processing 9, U3 small nucleolar RNA binding protein. (475 aa)
RAE1mRNA export factor; Plays a role in mitotic bipolar spindle formation. Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. (368 aa)
TBL1XUncharacterized protein. (615 aa)
GNB5G protein subunit beta 5. (420 aa)
PEX7Peroxisomal biogenesis factor 7. (308 aa)
BRWD3Bromodomain and WD repeat domain containing 3. (1799 aa)
TLE4TLE family member 4, transcriptional corepressor. (774 aa)
FBXW2F-box domain-containing protein. (234 aa)
BRWD1Bromodomain and WD repeat domain containing 1. (2325 aa)
GTF3C2General transcription factor IIIC subunit 2. (892 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
WDR1WD repeat-containing protein 1 isoform 1. (606 aa)
LOC100624648F-box-like/WD repeat-containing protein TBL1X isoform a. (529 aa)
WSB1WD repeat and SOCS box-containing protein 1 isoform 1. (421 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (492 aa)
WDR53WD repeat-containing protein 53 isoform a. (358 aa)
CDC40Pre-mRNA-processing factor 17. (579 aa)
GEMIN5Gem nuclear organelle associated protein 5. (1511 aa)
TBL2Transducin beta like 2. (465 aa)
WDR37WD repeat domain 37. (681 aa)
GNB4G protein subunit beta 4. (340 aa)
STRN4Striatin-4 isoform 2. (891 aa)
ATG16L1Autophagy-related protein 16-1 isoform X1. (623 aa)
WDR59WD repeat domain 59. (938 aa)
DDB2DNA damage-binding protein 2 isoform WT. (448 aa)
NLE1Notchless homolog 1. (487 aa)
STXBP5LSyntaxin binding protein 5 like. (1234 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1249 aa)
DENND3DENN domain containing 3. (1277 aa)
WDR97WD_REPEATS_REGION domain-containing protein. (795 aa)
TBL1XR1Transducin beta like 1 X-linked receptor 1. (526 aa)
RBBP4WD_REPEATS_REGION domain-containing protein. (427 aa)
TLE1TLE family member 1, transcriptional corepressor. (770 aa)
RBBP7RB binding protein 7, chromatin remodeling factor. (469 aa)
KIF21AKinesin family member 21A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1673 aa)
WDFY4WDFY family member 4. (1979 aa)
EML5EMAP like 5. (1969 aa)
CDC20BCell division cycle 20B. (516 aa)
SEC31BSEC31 homolog B, COPII coat complex component. (1210 aa)
ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (396 aa)
WDR41WD repeat-containing protein 41 isoform X1. (459 aa)
PHIPPleckstrin homology domain interacting protein. (1825 aa)
WDR48WD repeat domain 48. (740 aa)
TLE2TLE family member 2, transcriptional corepressor. (750 aa)
WDR11WD repeat domain 11. (1223 aa)
WDR47WD repeat domain 47. (928 aa)
AAASAladin WD repeat nucleoporin. (554 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (603 aa)
COPACoatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1241 aa)
KATNB1Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...] (690 aa)
WDR86WD_REPEATS_REGION domain-containing protein. (557 aa)
WDR31WD repeat domain 31. (376 aa)
NEDD1NEDD1 gamma-tubulin ring complex targeting factor. (654 aa)
WDSUB1WD repeat, sterile alpha motif and U-box domain containing 1. (476 aa)
NUP43Nucleoporin Nup43 isoform X2. (380 aa)
KIF21BKinesin family member 21B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1379 aa)
NUP37Nucleoporin Nup37. (333 aa)
DCAF7DDB1 and CUL4 associated factor 7. (340 aa)
CORO2ACoronin; Belongs to the WD repeat coronin family. (505 aa)
CSTF1Cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa. (431 aa)
DPH7Diphthamide biosynthesis 7. (471 aa)
WDR7WD repeat domain 7. (1487 aa)
TBL3Transducin beta like 3. (889 aa)
CORO1BCoronin; Belongs to the WD repeat coronin family. (496 aa)
THOC6THO complex subunit 6 homolog isoform 1. (406 aa)
FZR1Fizzy and cell division cycle 20 related 1. (493 aa)
STRN3Striatin 3. (797 aa)
GNB1G protein subunit beta 1. (395 aa)
FBXW11F-box and WD repeat domain containing 11. (542 aa)
SPAG16Sperm associated antigen 16. (628 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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