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ATP2C1 ATP2C1 NT5M NT5M PMM1 PMM1 HDHD5 HDHD5 ATP8B4 ATP8B4 ATP9B ATP9B ATP8B1 ATP8B1 LOC100156421 LOC100156421 CTDP1 CTDP1 ATP1A1 ATP1A1 LPIN3 LPIN3 NT5DC4 NT5DC4 ATP10D ATP10D ENOPH1 ENOPH1 ACAD10 ACAD10 NT5DC2 NT5DC2 ATP2B2 ATP2B2 ATP13A4 ATP13A4 PMM2 PMM2 NT5DC1 NT5DC1 ATP2B3 ATP2B3 ATP13A5 ATP13A5 ATP8B3 ATP8B3 PUDP PUDP CTDNEP1 CTDNEP1 NT5C NT5C ATP12A ATP12A ATP8B2 ATP8B2 LOC100625134 LOC100625134 NT5C3A NT5C3A ATP1A4 ATP1A4 ATP11C ATP11C PSPH PSPH ATP2A3 ATP2A3 ATP1A3 ATP1A3 NT5C3B NT5C3B PITPNM1 PITPNM1 ATP13A3 ATP13A3 CTDSPL2 CTDSPL2 ATP2A2 ATP2A2 ATP10B ATP10B ATP2B1 ATP2B1 PITPNM2 PITPNM2 HDHD3 HDHD3 ATP7B ATP7B EPHX2 EPHX2 ATP8A2 ATP8A2 CTDSP1 CTDSP1 HDHD2 HDHD2 A0A287AHT6_PIG A0A287AHT6_PIG ATP2A1 ATP2A1 LHPP LHPP ATP2B4 ATP2B4 CTDSP2 CTDSP2 A0A287AXH2_PIG A0A287AXH2_PIG PDXP PDXP MDP1 MDP1 ATP11B ATP11B ATP11A ATP11A NT5C2 NT5C2 PGP PGP ATP10A ATP10A PUDP-2 PUDP-2 UBLCP1 UBLCP1 CMAS CMAS ATP13A1 ATP13A1 NT5DC3 NT5DC3 PITPNM3 PITPNM3 ATP4A ATP4A PHOSPHO2 PHOSPHO2 ATP2C2 ATP2C2 CTDSPL CTDSPL TIMM50 TIMM50
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATP2C1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (949 aa)
NT5M5',3'-nucleotidase, mitochondrial. (228 aa)
PMM1Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (262 aa)
HDHD5Haloacid dehalogenase like hydrolase domain containing 5. (413 aa)
ATP8B4Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1199 aa)
ATP9BPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1140 aa)
ATP8B1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1256 aa)
LOC100156421Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1143 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (929 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha-1; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. (1028 aa)
LPIN3LNS2 domain-containing protein. (826 aa)
NT5DC45'-nucleotidase domain containing 4. (421 aa)
ATP10DPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1423 aa)
ENOPH1Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (312 aa)
ACAD10Acyl-CoA dehydrogenase family member 10. (1036 aa)
NT5DC25'-nucleotidase domain containing 2. (557 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1235 aa)
ATP13A4Uncharacterized protein. (212 aa)
PMM2Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (310 aa)
NT5DC15'-nucleotidase domain containing 1. (452 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1193 aa)
ATP13A5Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1219 aa)
ATP8B3Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1441 aa)
PUDPPseudouridine-5'-phosphatase isoform b. (231 aa)
CTDNEP1CTD nuclear envelope phosphatase 1. (244 aa)
NT5C5', 3'-nucleotidase, cytosolic. (255 aa)
ATP12ASodium/potassium-transporting ATPase subunit alpha. (1044 aa)
ATP8B2Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1209 aa)
LOC100625134Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1119 aa)
NT5C3A5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (313 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1030 aa)
ATP11CPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1132 aa)
PSPHPhosphoserine phosphatase isoform X1. (225 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1020 aa)
ATP1A3Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1287 aa)
NT5C3B5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (300 aa)
PITPNM1Phosphatidylinositol transfer protein membrane associated 1. (1243 aa)
ATP13A3Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1312 aa)
CTDSPL2CTD small phosphatase like 2. (437 aa)
ATP2A2Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Isoform SERCA2A is involved in the regulation of the contraction/relaxation cycle. Acts as a regulator of TNFSF11-mediated Ca(2+) signaling pathways via its interaction with TMEM64 which is critical for the TNFSF11-induced CREB1 activation and mitochondrial ROS generation necessary for proper osteoclast generation. Association between TMEM64 and SERCA2 in the ER leads to cytos [...] (1042 aa)
ATP10BPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1464 aa)
ATP2B1Plasma membrane calcium-transporting ATPase 1; Catalyzes the hydrolysis of ATP coupled with the transport of calcium from the cytoplasm to the extracellular space thereby maintaining intracellular calcium homeostasis. Plays a role in blood pressure regulation through regulation of intracellular calcium concentration and nitric oxide production leading to regulation of vascular smooth muscle cells vasoconstriction. Positively regulates bone mineralization through absorption of calcium from the intestine. Plays dual roles in osteoclast differentiation and survival by regulating RANKL-ind [...] (1249 aa)
PITPNM2Phosphatidylinositol transfer protein membrane associated 2. (1326 aa)
HDHD3Haloacid dehalogenase like hydrolase domain containing 3. (251 aa)
ATP7BUncharacterized protein. (275 aa)
EPHX2Bifunctional epoxide hydrolase 2; Bifunctional enzyme. The C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides (By similarity). Also determines steady- state levels of physiological mediators. The N- terminal domain has lipid phosphatase activity, with the highest activity towards threo-9,10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro-9,10-phosphonooxy-hydroxy-octadecanoic acid, 12- phosphonooxy-octadec-9Z-enoic acid and 12-phosphon [...] (575 aa)
ATP8A2Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1188 aa)
CTDSP1CTD small phosphatase 1. (261 aa)
HDHD2Haloacid dehalogenase like hydrolase domain containing 2. (259 aa)
A0A287AHT6_PIGPhosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (226 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1021 aa)
LHPPPhospholysine phosphohistidine inorganic pyrophosphate phosphatase. (273 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1171 aa)
CTDSP2FCP1 homology domain-containing protein. (324 aa)
A0A287AXH2_PIGUncharacterized protein. (284 aa)
PDXPPyridoxal phosphatase; Belongs to the HAD-like hydrolase superfamily. (296 aa)
MDP1Magnesium-dependent phosphatase 1 isoform 1. (164 aa)
ATP11BPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1232 aa)
ATP11APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1141 aa)
NT5C25'-nucleotidase, cytosolic II. (570 aa)
PGPPhosphoglycolate phosphatase; Belongs to the HAD-like hydrolase superfamily. (321 aa)
ATP10APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (974 aa)
PUDP-2Uncharacterized protein. (219 aa)
UBLCP1Ubiquitin-like domain-containing CTD phosphatase 1. (318 aa)
CMASCytidine monophosphate N-acetylneuraminic acid synthetase. (542 aa)
ATP13A1Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1252 aa)
NT5DC35'-nucleotidase domain containing 3. (518 aa)
PITPNM3PITPNM family member 3. (1730 aa)
ATP4APotassium-transporting ATPase alpha chain 1; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach. (1041 aa)
PHOSPHO2Pyridoxal phosphate phosphatase PHOSPHO2. (241 aa)
ATP2C2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (947 aa)
CTDSPLCTD small phosphatase like. (284 aa)
TIMM50Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (355 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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