(52 nodes) 7 transmembrane receptor (Secretin family) network (Sus scrofa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CRHR2	Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (482 aa)
	LOC100522787	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (700 aa)
	ADGRF4	Adhesion G protein-coupled receptor F4; Belongs to the G-protein coupled receptor 2 family. (691 aa)
	ADGRE3	Adhesion G protein-coupled receptor E3; Belongs to the G-protein coupled receptor 2 family. (642 aa)
	CRHR1	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (415 aa)
	GHRHR	Growth hormone-releasing hormone receptor; Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion. (451 aa)
	PTH2R	Parathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family. (550 aa)
	CELSR3	Cadherin EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family. (3309 aa)
	GPR143	Uncharacterized protein. (405 aa)
	ADGRD1	Adhesion G-protein coupled receptor D1 isoform 2; Belongs to the G-protein coupled receptor 2 family. (906 aa)
	ADGRD2	Adhesion G protein-coupled receptor D2; Belongs to the G-protein coupled receptor 2 family. (870 aa)
	SCTR	Secretin receptor; Belongs to the G-protein coupled receptor 2 family. (443 aa)
	ADGRG3	Adhesion G protein-coupled receptor G3; Belongs to the G-protein coupled receptor 2 family. (550 aa)
	ADGRF1	Adhesion G-protein coupled receptor F1 isoform 1; Belongs to the G-protein coupled receptor 2 family. (927 aa)
	ADGRF5	Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1340 aa)
	ADGRF3	Adhesion G protein-coupled receptor F3; Belongs to the G-protein coupled receptor 2 family. (998 aa)
	ADGRE5	Adhesion G protein-coupled receptor E5; Belongs to the G-protein coupled receptor 2 family. (828 aa)
	LOC100516420	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (674 aa)
	ADGRG7	Adhesion G protein-coupled receptor G7; Belongs to the G-protein coupled receptor 2 family. (797 aa)
	LOC110259331	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (788 aa)
	GLP2R	Glucagon like peptide 2 receptor; Belongs to the G-protein coupled receptor 2 family. (556 aa)
	ADGRE1	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (1474 aa)
	ADGRG1	Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (740 aa)
	ADGRA1	Adhesion G protein-coupled receptor A1; Belongs to the G-protein coupled receptor 2 family. (572 aa)
	GPR143-2	Uncharacterized protein. (412 aa)
	ADGRL1	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family. (1473 aa)
	CALCRL	Calcitonin gene-related peptide type 1 receptor; Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity). (463 aa)
	ADGRB2	Adhesion G protein-coupled receptor B2; Belongs to the G-protein coupled receptor 2 family. (1581 aa)
	VIPR2	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (465 aa)
	GPR157	G protein-coupled receptor 157. (334 aa)
	CELSR2	Cadherin EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family. (2917 aa)
	ADCYAP1R1	Pituitary adenylate cyclase-activating polypeptide type I receptor short form; Belongs to the G-protein coupled receptor 2 family. (468 aa)
	ADGRV1	Adhesion G protein-coupled receptor V1. (6313 aa)
	ADGRA3	Adhesion G protein-coupled receptor A3; Belongs to the G-protein coupled receptor 2 family. (1317 aa)
	ADGRL4	Adhesion G protein-coupled receptor L4; Belongs to the G-protein coupled receptor 2 family. (741 aa)
	ADGRL2	Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family. (1479 aa)
	ADGRG6	Adhesion G protein-coupled receptor G6; Belongs to the G-protein coupled receptor 2 family. (1247 aa)
	ADGRB1	Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1550 aa)
	ADGRG5	Adhesion G protein-coupled receptor G5; Belongs to the G-protein coupled receptor 2 family. (557 aa)
	LOC100516957	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (955 aa)
	ADGRB3	Adhesion G protein-coupled receptor B3; Belongs to the G-protein coupled receptor 2 family. (1522 aa)
	CALCR	Calcitonin receptor; This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin. The receptor can also couple to an additional signaling pathway via a pertussis toxin-sensitive g protein in isolated osteoclasts and in LLC-PK1 cells; Belongs to the G-protein coupled receptor 2 family. (490 aa)
	CELSR1	Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (3320 aa)
	VIPR1	Vasoactive intestinal polypeptide receptor 1; This is a receptor for VIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity). Belongs to the G-protein coupled receptor 2 family. (458 aa)
	LOC100518417	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (834 aa)
	EMR4	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (723 aa)
	ADGRA2	Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1336 aa)
	GIPR	Gastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. (466 aa)
	ADGRG2	Adhesion G protein-coupled receptor G2; Belongs to the G-protein coupled receptor 2 family. (1021 aa)
	GLP1R	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (468 aa)
	GCGR	G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family. (602 aa)
	PTH1R	Parathyroid hormone/parathyroid hormone-related peptide receptor; Receptor for parathyroid hormone and for parathyroid hormone- related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 2 family. (641 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADGRA1	ADGRG1	ENSSSCP00000036686	ENSSSCP00000035142	Adhesion G protein-coupled receptor A1; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family.	0.685
ADGRA1	ADGRL1	ENSSSCP00000036686	ENSSSCP00000037086	Adhesion G protein-coupled receptor A1; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	0.701
ADGRA1	ADGRL2	ENSSSCP00000036686	ENSSSCP00000052051	Adhesion G protein-coupled receptor A1; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family.	0.683
ADGRA2	ADGRF1	ENSSSCP00000064812	ENSSSCP00000001883	Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family.	Adhesion G-protein coupled receptor F1 isoform 1; Belongs to the G-protein coupled receptor 2 family.	0.678
ADGRA2	ADGRF3	ENSSSCP00000064812	ENSSSCP00000025251	Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor F3; Belongs to the G-protein coupled receptor 2 family.	0.518
ADGRA2	ADGRF4	ENSSSCP00000064812	ENSSSCP00000021241	Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor F4; Belongs to the G-protein coupled receptor 2 family.	0.625
ADGRA2	ADGRF5	ENSSSCP00000064812	ENSSSCP00000001882	Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family.	0.451
ADGRA2	ADGRG1	ENSSSCP00000064812	ENSSSCP00000035142	Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family.	0.407
ADGRA2	ADGRG3	ENSSSCP00000064812	ENSSSCP00000003033	Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor G3; Belongs to the G-protein coupled receptor 2 family.	0.592
ADGRA2	ADGRL1	ENSSSCP00000064812	ENSSSCP00000037086	Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	0.843
ADGRA2	ADGRL2	ENSSSCP00000064812	ENSSSCP00000052051	Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family.	0.759
ADGRA3	ADGRF3	ENSSSCP00000047176	ENSSSCP00000025251	Adhesion G protein-coupled receptor A3; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor F3; Belongs to the G-protein coupled receptor 2 family.	0.516
ADGRA3	ADGRF4	ENSSSCP00000047176	ENSSSCP00000021241	Adhesion G protein-coupled receptor A3; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor F4; Belongs to the G-protein coupled receptor 2 family.	0.622
ADGRA3	ADGRG3	ENSSSCP00000047176	ENSSSCP00000003033	Adhesion G protein-coupled receptor A3; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor G3; Belongs to the G-protein coupled receptor 2 family.	0.554
ADGRA3	ADGRG5	ENSSSCP00000047176	ENSSSCP00000056523	Adhesion G protein-coupled receptor A3; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor G5; Belongs to the G-protein coupled receptor 2 family.	0.615
ADGRA3	ADGRL1	ENSSSCP00000047176	ENSSSCP00000037086	Adhesion G protein-coupled receptor A3; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	0.732
ADGRA3	ADGRL2	ENSSSCP00000047176	ENSSSCP00000052051	Adhesion G protein-coupled receptor A3; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family.	0.779
ADGRB1	ADGRL1	ENSSSCP00000054635	ENSSSCP00000037086	Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	0.471
ADGRF1	ADGRA2	ENSSSCP00000001883	ENSSSCP00000064812	Adhesion G-protein coupled receptor F1 isoform 1; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family.	0.678
ADGRF1	ADGRG5	ENSSSCP00000001883	ENSSSCP00000056523	Adhesion G-protein coupled receptor F1 isoform 1; Belongs to the G-protein coupled receptor 2 family.	Adhesion G protein-coupled receptor G5; Belongs to the G-protein coupled receptor 2 family.	0.530