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KCNQ1 KCNQ1 SCN10A SCN10A PKD2L1 PKD2L1 PKD2 PKD2 HCN3 HCN3 TRPA1 TRPA1 TRPM6 TRPM6 TRPM1 TRPM1 TRPM7 TRPM7 CNGB1 CNGB1 HCN4 HCN4 CACNA1I CACNA1I TRPC5 TRPC5 CNGA2 CNGA2 CNGA4 CNGA4 CACNA1E CACNA1E SCN3A SCN3A TRPM8 TRPM8 SCN4A SCN4A CACNA1G CACNA1G TRPV3 TRPV3 TRPM2 TRPM2 HCN1 HCN1 CNGA3 CNGA3 SCN7A SCN7A PKD2L2 PKD2L2 SCN11A SCN11A ITPR2 ITPR2 CATSPER4 CATSPER4 CACNA1H CACNA1H SCN2A SCN2A NALCN NALCN TRPV2 TRPV2 CACNA1A CACNA1A LOC100620627 LOC100620627 CACNA1C CACNA1C CACNA1B CACNA1B HCN2 HCN2 SCN9A SCN9A TRPM4 TRPM4 CACNA1D CACNA1D CACNA1F CACNA1F TRPV5 TRPV5 TPCN1 TPCN1 ITPR3 ITPR3 CATSPER2 CATSPER2 SLC9C1 SLC9C1 SCN1A SCN1A TRPC1 TRPC1 TRPV1 TRPV1 SCN8A SCN8A HVCN1 HVCN1 A0A5G2Q7N9_PIG A0A5G2Q7N9_PIG CACNA1S CACNA1S TRPV4 TRPV4 ITPR1 ITPR1 TRPM3 TRPM3 TRPC4 TRPC4 CNGA1 CNGA1 RYR3 RYR3 TPCN2 TPCN2 RYR2 RYR2 SCN5A SCN5A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (771 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1950 aa)
PKD2L1Polycystin 2 like 1, transient receptor potential cation channel. (791 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (970 aa)
HCN3Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3. (784 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1145 aa)
TRPM6Transient receptor potential cation channel subfamily M member 6. (2027 aa)
TRPM1Transient receptor potential cation channel subfamily M member 1. (1641 aa)
TRPM7Transient receptor potential cation channel subfamily M member 7. (1886 aa)
CNGB1Cyclic nucleotide-binding domain-containing protein. (1165 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1199 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2118 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
CNGA2Cyclic nucleotide gated channel subunit alpha 2. (663 aa)
CNGA4Cyclic nucleotide gated channel subunit alpha 4. (591 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2447 aa)
SCN3ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1982 aa)
TRPM8Transient receptor potential cation channel subfamily M member 8. (1104 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1830 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2381 aa)
TRPV3Transient receptor potential cation channel subfamily V member 3; Belongs to the transient receptor (TC 1.A.4) family. (790 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1538 aa)
HCN1Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1. (885 aa)
CNGA3Cyclic nucleotide gated channel subunit alpha 3. (675 aa)
SCN7ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1677 aa)
PKD2L2Polycystin 2 like 2, transient receptor potential cation channel. (625 aa)
SCN11ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1785 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2702 aa)
CATSPER4Cation channel sperm associated 4. (471 aa)
CACNA1HVoltage-dependent T-type calcium channel subunit alpha-1H isoform a. (2328 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2006 aa)
NALCNSodium leak channel non-selective protein isoform X1. (1738 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (854 aa)
CACNA1AUncharacterized protein. (434 aa)
LOC100620627Uncharacterized protein. (780 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1291 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2329 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (897 aa)
SCN9ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1987 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4 isoform X1. (1213 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2211 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1977 aa)
TRPV5Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family. (792 aa)
TPCN1Two pore calcium channel protein 1 isoform X1. (817 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2680 aa)
CATSPER2Cation channel sperm associated 2. (538 aa)
SLC9C1Solute carrier family 9 member C1. (1141 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2009 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (832 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1980 aa)
HVCN1Hydrogen voltage gated channel 1. (346 aa)
A0A5G2Q7N9_PIGIon_trans domain-containing protein. (292 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (924 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2759 aa)
TRPM3Transient receptor potential cation channel subfamily M member 3. (1710 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (982 aa)
CNGA1Cyclic nucleotide gated channel subunit alpha 1. (737 aa)
RYR3Ryanodine receptor 3. (4871 aa)
TPCN2Uncharacterized protein. (765 aa)
RYR2Ryanodine receptor 2. (4966 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1887 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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