13 items (Sus scrofa) - STRING interaction network

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Your Input:
	KLRK1	NKG2-D type II integral membrane protein; Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress- inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-exp [...] (221 aa)
	PSMB8	Proteasome subunit beta type-8; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. May participate in the generation of spliced peptides resulting from the ligation of two separate proteasomal cleavage products that are not contiguous in the parental protein (By similarity). Required for adip [...] (295 aa)
	NCR3	Uncharacterized protein. (136 aa)
	PSMB10	Proteasome subunit beta. (296 aa)
	TRIM39	E3 ubiquitin-protein ligase TRIM39 isoform 2. (488 aa)
	PPP1R11	Protein phosphatase 1 regulatory inhibitor subunit 11. (126 aa)
	POU5F1	POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. Belongs to the POU transcription factor family. Class-5 subfamily. (361 aa)
	HLA-DRA	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (252 aa)
	HLA-DOB	HLA class II histocompatibility antigen, DO beta chain. (277 aa)
	SLA-DMB	Major histocompatibility complex, class II, DM beta. (272 aa)
	CD4	CD4 molecule. (494 aa)
	HTATSF1	HIV-1 Tat specific factor 1. (684 aa)
	TRIM26	Tripartite motif-containing protein 26; E3 ubiquitin-protein ligase which regulates the IFN-beta production and antiviral response downstream of various DNA-encoded pattern-recognition receptors (PRRs). Promotes nuclear IRF3 ubiquitination and proteasomal degradation. Bridges together TBK1 and NEMO during the innate response to viral infection leading to the activation of TBK1. (538 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD4	HLA-DOB	ENSSSCP00000019155	ENSSSCP00000001577	CD4 molecule.	HLA class II histocompatibility antigen, DO beta chain.	0.510
CD4	HLA-DRA	ENSSSCP00000019155	ENSSSCP00000001567	CD4 molecule.	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.	0.936
CD4	KLRK1	ENSSSCP00000019155	ENSSSCP00000034632	CD4 molecule.	NKG2-D type II integral membrane protein; Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress- inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-exp [...]	0.693
HLA-DOB	CD4	ENSSSCP00000001577	ENSSSCP00000019155	HLA class II histocompatibility antigen, DO beta chain.	CD4 molecule.	0.510
HLA-DOB	HLA-DRA	ENSSSCP00000001577	ENSSSCP00000001567	HLA class II histocompatibility antigen, DO beta chain.	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.	0.926
HLA-DOB	PSMB8	ENSSSCP00000001577	ENSSSCP00000037739	HLA class II histocompatibility antigen, DO beta chain.	Proteasome subunit beta type-8; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. May participate in the generation of spliced peptides resulting from the ligation of two separate proteasomal cleavage products that are not contiguous in the parental protein (By similarity). Required for adip [...]	0.417
HLA-DOB	SLA-DMB	ENSSSCP00000001577	ENSSSCP00000001591	HLA class II histocompatibility antigen, DO beta chain.	Major histocompatibility complex, class II, DM beta.	0.887
HLA-DRA	CD4	ENSSSCP00000001567	ENSSSCP00000019155	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.	CD4 molecule.	0.936
HLA-DRA	HLA-DOB	ENSSSCP00000001567	ENSSSCP00000001577	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.	HLA class II histocompatibility antigen, DO beta chain.	0.926
HLA-DRA	KLRK1	ENSSSCP00000001567	ENSSSCP00000034632	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.	NKG2-D type II integral membrane protein; Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress- inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-exp [...]	0.447
HLA-DRA	PSMB8	ENSSSCP00000001567	ENSSSCP00000037739	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.	Proteasome subunit beta type-8; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. May participate in the generation of spliced peptides resulting from the ligation of two separate proteasomal cleavage products that are not contiguous in the parental protein (By similarity). Required for adip [...]	0.601
HLA-DRA	SLA-DMB	ENSSSCP00000001567	ENSSSCP00000001591	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.	Major histocompatibility complex, class II, DM beta.	0.990
HTATSF1	NCR3	ENSSSCP00000021619	ENSSSCP00000051317	HIV-1 Tat specific factor 1.	Uncharacterized protein.	0.764
HTATSF1	PSMB10	ENSSSCP00000021619	ENSSSCP00000058852	HIV-1 Tat specific factor 1.	Proteasome subunit beta.	0.539
KLRK1	CD4	ENSSSCP00000034632	ENSSSCP00000019155	NKG2-D type II integral membrane protein; Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress- inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-exp [...]	CD4 molecule.	0.693
KLRK1	HLA-DRA	ENSSSCP00000034632	ENSSSCP00000001567	NKG2-D type II integral membrane protein; Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress- inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-exp [...]	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.	0.447
KLRK1	NCR3	ENSSSCP00000034632	ENSSSCP00000051317	NKG2-D type II integral membrane protein; Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress- inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-exp [...]	Uncharacterized protein.	0.465
NCR3	HTATSF1	ENSSSCP00000051317	ENSSSCP00000021619	Uncharacterized protein.	HIV-1 Tat specific factor 1.	0.764
NCR3	KLRK1	ENSSSCP00000051317	ENSSSCP00000034632	Uncharacterized protein.	NKG2-D type II integral membrane protein; Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress- inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-exp [...]	0.465
NCR3	PSMB10	ENSSSCP00000051317	ENSSSCP00000058852	Uncharacterized protein.	Proteasome subunit beta.	0.454