9 items (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RUBCN	KIAA0226 protein transcript variant 2. (971 aa)
	LMLN	Leishmanolysin-like peptidase. (694 aa)
	MUC13	Uncharacterized protein. (537 aa)
	TFRC	Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity). (794 aa)
	MUC20	Uncharacterized protein. (599 aa)
	TBP	Uncharacterized protein. (153 aa)
	MUC4	Uncharacterized protein. (1173 aa)
	HMBS	Porphobilinogen deaminase isoform 1. (361 aa)
	RPL4	60S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family. (449 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HMBS	RPL4	ENSSSCP00000053595	ENSSSCP00000061269	Porphobilinogen deaminase isoform 1.	60S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family.	0.814
HMBS	TBP	ENSSSCP00000053595	ENSSSCP00000040424	Porphobilinogen deaminase isoform 1.	Uncharacterized protein.	0.867
HMBS	TFRC	ENSSSCP00000053595	ENSSSCP00000029501	Porphobilinogen deaminase isoform 1.	Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity).	0.414
MUC13	MUC20	ENSSSCP00000012633	ENSSSCP00000033626	Uncharacterized protein.	Uncharacterized protein.	0.952
MUC13	MUC4	ENSSSCP00000012633	ENSSSCP00000051590	Uncharacterized protein.	Uncharacterized protein.	0.956
MUC13	TFRC	ENSSSCP00000012633	ENSSSCP00000029501	Uncharacterized protein.	Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity).	0.431
MUC20	MUC13	ENSSSCP00000033626	ENSSSCP00000012633	Uncharacterized protein.	Uncharacterized protein.	0.952
MUC20	MUC4	ENSSSCP00000033626	ENSSSCP00000051590	Uncharacterized protein.	Uncharacterized protein.	0.968
MUC20	RUBCN	ENSSSCP00000033626	ENSSSCP00000012624	Uncharacterized protein.	KIAA0226 protein transcript variant 2.	0.404
MUC20	TFRC	ENSSSCP00000033626	ENSSSCP00000029501	Uncharacterized protein.	Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity).	0.454
MUC4	MUC13	ENSSSCP00000051590	ENSSSCP00000012633	Uncharacterized protein.	Uncharacterized protein.	0.956
MUC4	MUC20	ENSSSCP00000051590	ENSSSCP00000033626	Uncharacterized protein.	Uncharacterized protein.	0.968
MUC4	TFRC	ENSSSCP00000051590	ENSSSCP00000029501	Uncharacterized protein.	Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity).	0.405
RPL4	HMBS	ENSSSCP00000061269	ENSSSCP00000053595	60S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family.	Porphobilinogen deaminase isoform 1.	0.814
RPL4	TBP	ENSSSCP00000061269	ENSSSCP00000040424	60S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family.	Uncharacterized protein.	0.797
RPL4	TFRC	ENSSSCP00000061269	ENSSSCP00000029501	60S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family.	Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity).	0.585
RUBCN	MUC20	ENSSSCP00000012624	ENSSSCP00000033626	KIAA0226 protein transcript variant 2.	Uncharacterized protein.	0.404
TBP	HMBS	ENSSSCP00000040424	ENSSSCP00000053595	Uncharacterized protein.	Porphobilinogen deaminase isoform 1.	0.867
TBP	RPL4	ENSSSCP00000040424	ENSSSCP00000061269	Uncharacterized protein.	60S ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family.	0.797
TBP	TFRC	ENSSSCP00000040424	ENSSSCP00000029501	Uncharacterized protein.	Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity).	0.455